Magnetic resonance jet velocity mapping in mitral and aortic valve stenosis.

abstract：BACKGROUND:Angina symptoms have been reported to predict mortality in men. The aim of this study was to investigate the association between angina symptoms and mortality in women. METHODS AND RESULTS:In 2004, 873 older participants in the Australian Longitudinal Study on Women's Health with self-reported ischemic hear...

journal_title：Circulation

authors： Berecki-Gisolf J,Humphreyes-Reid L,Wilson A,Dobson A

更新日期：2009-12-08 00:00:00

abstract：BACKGROUND:Serotonin (5-hydroxytryptamine; 5-HT) overproduction is responsible for cardiac valvular disease in patients with carcinoid tumors. Reduced 5-HT inactivation is one proposed mechanism of the valvulopathy observed in individuals treated with the appetite suppressants fenfluramine and phentermine. One key prot...

journal_title：Circulation

authors： Mekontso-Dessap A,Brouri F,Pascal O,Lechat P,Hanoun N,Lanfumey L,Seif I,Benhaiem-Sigaux N,Kirsch M,Hamon M,Adnot S,Eddahibi S

更新日期：2006-01-03 00:00:00

abstract：BACKGROUND:Exercise stimulates the vascular response in pathological conditions, including ischemia; however, the molecular mechanisms by which exercise improves the impaired hypoxia-induced factor (HIF)-1 alpha-mediated response to hypoxia associated with aging are poorly understood. Here, we report that swimming trai...

journal_title：Circulation

authors： Cheng XW,Kuzuya M,Kim W,Song H,Hu L,Inoue A,Nakamura K,Di Q,Sasaki T,Tsuzuki M,Shi GP,Okumura K,Murohara T

更新日期：2010-08-17 00:00:00

abstract：BACKGROUND:Factor Xa plays a central role in the generation of thrombin, making it a novel target for treatment of arterial thrombosis. Fondaparinux is a synthetic factor Xa inhibitor that has been shown to be superior to standard therapies for the prevention of venous thrombosis. We performed a randomized trial to det...

journal_title：Circulation

authors： Mehta SR,Steg PG,Granger CB,Bassand JP,Faxon DP,Weitz JI,Afzal R,Rush B,Peters RJ,Natarajan MK,Velianou JL,Goodhart DM,Labinaz M,Tanguay JF,Fox KA,Yusuf S,ASPIRE Investigators.

更新日期：2005-03-22 00:00:00

abstract：BACKGROUND:Ventricular tachyarrhythmias are the major clinical manifestation of arrhythmogenic right ventricular disease. Although antiarrhythmic therapy has been widely advocated, there is only limited information available on the efficacy of antiarrhythmic drugs in these patients. METHODS AND RESULTS:The short- and ...

journal_title：Circulation

authors： Wichter T,Borggrefe M,Haverkamp W,Chen X,Breithardt G

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:Current guidelines recommend mitral valve surgery for asymptomatic patients with severe degenerative mitral regurgitation and preserved left ventricular systolic function when exercise pulmonary hypertension (PHT) is present. However, the determinants of exercise PHT have not been evaluated. The aim of this ...

journal_title：Circulation

authors： Magne J,Lancellotti P,Piérard LA

更新日期：2010-07-06 00:00:00

abstract：:We have shown previously that the physical properties of myocardium in dogs can be characterized with quantitative ultrasonic integrated backscatter and that interrogation of the tissue with ultrasound can delineate cardiac cycle-dependent changes in ultrasonic backscatter in normal tissue that disappear with ischemia...

journal_title：Circulation

authors： Vered Z,Barzilai B,Mohr GA,Thomas LJ 3rd,Genton R,Sobel BE,Shoup TA,Melton HE,Miller JG,Pérez JE

更新日期：1987-11-01 00:00:00

abstract：:In our approach to dynamic cardiomyoplasty, which consists of wrapping a skeletal muscle around the heart and stimulating the former in synchrony with heart contractions to augment ventricular contractility, we have transferred a latissimus dorsi muscle flap to the heart by way of a partial resection of the second rib...

journal_title：Circulation

authors： Chachques JC,Grandjean P,Schwartz K,Mihaileanu S,Fardeau M,Swynghedauw B,Fontaliran F,Romero N,Wisnewsky C,Perier P

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Vasoactive drugs could alter the fluid restitution from the tissue and redistribute blood volume between the macrocirculation and microcirculation. METHODS AND RESULTS:With bolus injections of vasoactive drugs in anesthetized rabbits, we measured the changes in blood and plasma density for the determination...

journal_title：Circulation

authors： Anderson SM,Rich GF,Roos C,Lee LP,Lee JS

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:In essential hypertension, endothelium-dependent vasodilation is impaired because of reduced nitric oxide (NO) availability, which is mainly caused by oxidative stress. The present study was designed to identify the mechanism(s) responsible for NO-independent vasodilation to bradykinin in patients with essen...

journal_title：Circulation

authors： Taddei S,Ghiadoni L,Virdis A,Buralli S,Salvetti A

更新日期：1999-09-28 00:00:00

abstract：BACKGROUND:The use of balloon coarctation angioplasty instead of surgery as treatment for unoperated coarctation of the aorta is controversial. The efficacy and complications of the two procedures have not been studied before in a prospective fashion. METHODS AND RESULTS:Thirty-six patients were prospectively randomiz...

journal_title：Circulation

authors： Shaddy RE,Boucek MM,Sturtevant JE,Ruttenberg HD,Jaffe RB,Tani LY,Judd VE,Veasy LG,McGough EC,Orsmond GS

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:Atrial fibrillation (AF) is the most common sustained arrhythmia; however, little is known about patients in a primary care setting from high-, middle-, and low-income countries. METHODS AND RESULTS:This prospective registry enrolled patients presenting to an emergency department with AF at 164 sites in 46 ...

journal_title：Circulation

authors： Oldgren J,Healey JS,Ezekowitz M,Commerford P,Avezum A,Pais P,Zhu J,Jansky P,Sigamani A,Morillo CA,Liu L,Damasceno A,Grinvalds A,Nakamya J,Reilly PA,Keltai K,Van Gelder IC,Yusufali AH,Watanabe E,Wallentin L,Connoll

更新日期：2014-04-15 00:00:00

abstract：BACKGROUND:Swimming-induced pulmonary edema (SIPE) occurs during swimming or scuba diving, often in young individuals with no predisposing conditions, and its pathophysiology is poorly understood. This study tested the hypothesis that pulmonary artery and pulmonary artery wedge pressures are higher in SIPE-susceptible ...

journal_title：Circulation

authors： Moon RE,Martina SD,Peacher DF,Potter JF,Wester TE,Cherry AD,Natoli MJ,Otteni CE,Kernagis DN,White WD,Freiberger JJ

更新日期：2016-03-08 00:00:00

abstract：BACKGROUND:Human endothelial and vascular smooth muscle cells synthesize prostanoids. Several of these have been implicated in the physiological and pathophysiological regulation of vascular tone; however, there is no direct evidence that human blood vessels synthesize sufficient prostanoid to alter vessel tone. METHO...

journal_title：Circulation

authors： Bhagat K,Collier J,Vallance P

更新日期：1995-10-15 00:00:00

abstract：:Since the discovery that neuregulin-1 (NRG-1)/ErbB signaling is indispensable in cardiac development, evidence has shown that this system also plays a crucial role in the adult heart. In patients, an inhibitory ErbB2 antibody, trastuzumab, used in the treatment of mammary carcinomas, increases the risk for the develop...

journal_title：Circulation

authors： Lemmens K,Doggen K,De Keulenaer GW

更新日期：2007-08-21 00:00:00

abstract：BACKGROUND:Television viewing time, the predominant leisure-time sedentary behavior, is associated with biomarkers of cardiometabolic risk, but its relationship with mortality has not been studied. We examined the associations of prolonged television viewing time with all-cause, cardiovascular disease (CVD), cancer, an...

journal_title：Circulation

authors： Dunstan DW,Barr EL,Healy GN,Salmon J,Shaw JE,Balkau B,Magliano DJ,Cameron AJ,Zimmet PZ,Owen N

更新日期：2010-01-26 00:00:00

abstract：BACKGROUND:The clinical significance and pathophysiological mechanisms of reverse redistribution on stress-redistribution thallium-201 myocardial scintigraphy in patients with chronic coronary artery disease are unclear. Recent studies have shown that thallium-201 reinjection is a useful technique for the detection of ...

journal_title：Circulation

authors： Marin-Neto JA,Dilsizian V,Arrighi JA,Freedman NM,Perrone-Filardi P,Bacharach SL,Bonow RO

更新日期：1993-10-01 00:00:00

abstract：:Over an 8-year period, 20 patients underwent operative repair of ventricular aneurysms during the first 8 weeks after acute myocardial infarction. All patients with multivessel coronary occlusive disease underwent concomitant coronary artery bypass grafting. There was one hospital death, for an early mortality rate o...

journal_title：Circulation

authors： Walker WE,Stoney WS,Alford WC Jr,Burrus GR,Glassford DM,Thomas CS Jr

更新日期：1980-08-01 00:00:00

abstract：:A consecutive series of 17 patients surgically treated for asymptomatic coronary artery disease was surveyed for survival, clinical status, and graft patency after a mean follow-up of 75 months. Documented myocardial infarction (MI), 14 transmural and 3 subendocardial, was the major indication for catheterization. All...

journal_title：Circulation

authors： Thurer RL,Lytle BW,Cosgrove DM,Loop FD

更新日期：1979-08-01 00:00:00

abstract：BACKGROUND:Imaging of the flow convergence region (FCR) proximal to a regurgitant orifice has been shown to provide a method for quantifying the regurgitant flow rate. According to the continuity principle, the FCR is constituted by concentric hemispheric isovelocity surfaces centered at the orifice. The flow rate is c...

journal_title：Circulation

authors： Bargiggia GS,Tronconi L,Sahn DJ,Recusani F,Raisaro A,De Servi S,Valdes-Cruz LM,Montemartini C

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND:The antiarrhythmic drugs quinidine and verapamil are known to block alpha1-adrenoceptors (alpha1ARs). Alpha1ARs are a heterogeneous family of three subtypes (alpha1A, alpha1B, and alpha1D), and little is known about the effects of quinidine and verapamil on the different human alpha1AR subtypes. METHODS AND...

journal_title：Circulation

authors： Shibata K,Hirasawa A,Foglar R,Ogawa S,Tsujimoto G

更新日期：1998-04-07 00:00:00

abstract：:The acute hemodynamic effects of dobutamine and nitroprusside were compared in 19 patients with low output cardiac failure. At dosage levels yielding similar increases in cardiac index (12 patients), nitroprusside resulted in significantly lower arterial systolic and wedge pressures and did not increase heart rate sug...

journal_title：Circulation

authors： Berkowitz C,McKeever L,Croke RP,Jacobs WR,Loeb HS,Gunnar RM

更新日期：1977-12-01 00:00:00

abstract：:Scanning and transmission electron microscopic studies were made of: 1) 15 glutaraldehyde-treated porcine valvular heterografts that had been implanted in patients for periods of time ranging from 2 days to 76 months; 2) unimplanted, commercially processed porcine aortic valves; and 3) unprocessed porcine aortic valve...

journal_title：Circulation

authors： Ferrans VJ,Spray TL,Billingham ME,Roberts WC

更新日期：1978-09-01 00:00:00

abstract：BACKGROUND:Polymorphisms of the beta fibrinogen gene have been shown to affect plasma fibrinogen levels and the risk of peripheral arterial disease. We now present the results of a detailed analysis of the beta fibrinogen gene in relation to plasma fibrinogen and to the severity of coronary artery disease (CAD) in pati...

journal_title：Circulation

authors： Behague I,Poirier O,Nicaud V,Evans A,Arveiler D,Luc G,Cambou JP,Scarabin PY,Bara L,Green F,Cambien F

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:Observational studies have identified an association between body mass index (BMI) and incident atrial fibrillation (AF). Inferring causality from observational studies, however, is subject to residual confounding, reverse causation, and bias. The primary objective of this study was to evaluate the causal as...

journal_title：Circulation

authors： Chatterjee NA,Giulianini F,Geelhoed B,Lunetta KL,Misialek JR,Niemeijer MN,Rienstra M,Rose LM,Smith AV,Arking DE,Ellinor PT,Heeringa J,Lin H,Lubitz SA,Soliman EZ,Verweij N,Alonso A,Benjamin EJ,Gudnason V,Stricker BHC

更新日期：2017-02-21 00:00:00

abstract：BACKGROUND:Emerging studies suggest that early administration of dual antiplatelet therapy may be better than monotherapy for prevention of early recurrent stroke and cardiovascular outcomes in acute ischemic stroke and transient ischemic attack (TIA). We performed a meta-analysis of randomized, controlled trials evalu...

journal_title：Circulation

authors： Wong KS,Wang Y,Leng X,Mao C,Tang J,Bath PM,Markus HS,Gorelick PB,Liu L,Lin W,Wang Y

更新日期：2013-10-08 00:00:00

abstract：BACKGROUND:Cystic medial degeneration (CMD) is a histological abnormality that is common in the aortic diseases associated with Marfan's syndrome (MFS). Although little known about the mechanism underlying CMD, several recent reports have demonstrated that vascular smooth muscle cell (VSMC) apoptosis could play a subst...

journal_title：Circulation

authors： Nagashima H,Sakomura Y,Aoka Y,Uto K,Kameyama Ki,Ogawa M,Aomi S,Koyanagi H,Ishizuka N,Naruse M,Kawana M,Kasanuki H

更新日期：2001-09-18 00:00:00

abstract：BACKGROUND:Repeated brief episodes of myocardial ischemia performed by mechanical clamping of a coronary artery "precondition" the heart and reduce infarct size after a subsequent sustained ischemia. It is not known, however, whether spontaneous episodes of transient ischemia caused by formation of platelet thrombi, wh...

journal_title：Circulation

authors： Ovize M,Kloner RA,Hale SL,Przyklenk K

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:Spontaneous transient outward potassium currents (STOCs) induce myogenic relaxation in small cerebral vessels. We found STOCs in human coronary artery vascular smooth muscle cells (VSMCs) and studied their regulation. METHODS AND RESULTS:K+ currents were recorded in human coronary VSMCs by current- and volt...

journal_title：Circulation

authors： Bychkov R,Gollasch M,Ried C,Luft FC,Haller H

更新日期：1997-01-21 00:00:00

abstract：BACKGROUND:The accumulation of macrophage-derived foam cells in atherosclerotic lesions correlates with increased local release of matrix-degrading metalloproteinases (MMPs) and a thin fibrous cap. The activity of these enzymes is controlled by specific tissue inhibitors of metalloproteinases (TIMPs). METHODS AND RESU...

journal_title：Circulation

authors： Moreau M,Brocheriou I,Petit L,Ninio E,Chapman MJ,Rouis M

更新日期：1999-01-26 00:00:00