Abstract:
:The panel of therapeutic options available for the treatment of retroviral disorders has expanded explosively in recent years with the result that it has now become possible to reconstitute the immune function of individuals with advanced HIV-disease to a remarkable degree. The ophthalmologist is thus confronted with completely new clinical situations, courses of treatment and decisions. For example, a CMV-retinitis developing within six weeks of the onset of HAART does not necessarily require specific treatment, and reactivation of a retinitis within the same time span is often barely distinguishable from an inflammatory reaction induced by the reconstituted lymphocytes. Marked cellular infiltration of the vitreous--in the absence of an active retinal or chorioretinal lesion--is the hallmark of this immune-recovery vitreitis and responds nicely to systemic steroid treatment. In the course of retinitis, macular edema and epiretinal membrane formation are not uncommonly responsible for visual impairment. If, on the other hand, immunological parameters remain stable during the course of three months, i.e., if the CD4 cell count is more than 150-250 microliters and the plasma load of HIV-1 is less than 5-10,000 copies/microliter, then what has until now been deemed to be a lifelong therapy for CMV-retinitis may be interrupted, provided the clinical (i.e., retinal) situation can be controlled on a regular basis. In this article, an attempt is made to discuss and interpret clinical findings pertaining to posterior segment involvement in ocular HIV disease, with a view to guiding the clinical practitioner in his/her course of action.
journal_name
Klin Monbl Augenheilkdjournal_title
Klinische Monatsblatter fur Augenheilkundeauthors
Garweg JGdoi
10.1055/s-2000-10520subject
Has Abstractpub_date
2000-02-01 00:00:00pages
68-74issue
2eissn
0023-2165issn
1439-3999journal_volume
216pub_type
杂志文章,评审abstract::Serious eye injuries occur mostly in the spheres of traffic, work and play. There is an inverse relationship between the length of the wound and the visual acuity. Various authors' groupings according to the type of injury, and the relationship between severity and acuity obtained are given and comprehensively describ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1976-09-01 00:00:00
abstract:BACKGROUND:We investigated the presence of Nicotinamid-adenin-dinucleotid-phosphat (NADPH)-diaphorase activity in endothelial cells of the human uveal vessels, using a histochemical procedure which presumably localizes the reaction product nitric oxide. MATERIAL AND METHODS:11 donor eyes destined for corneal transplan...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035414
更新日期:1995-02-01 00:00:00
abstract::Ovid's "De medicamine faciei feminae" contains the astonishing sentence "Culta placent - all that is artificial is beautiful". In his "Éloge du maquillage" Baudelaire, buidling on Ovid's argument, states that first culture as picture and construction of beauty brings forth the truth of Nature and claims that cosmetics...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0032-1328108
更新日期:2013-01-01 00:00:00
abstract::In the presence of leukokoria the diagnosis of retinoblastoma is usually easy when the mediae are transparent. If they are not, however, one is frequently obliged to enucleate a painful or useless eye in order to rule out this diagnosis. In a series of eight cases having undergone enucleation for this reason at the La...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1057514
更新日期:1980-04-01 00:00:00
abstract::The authors report on the techniques of laser treatment of diabetic maculopathy: focal direct laser coagulation of I.R.M.A. in exudative maculopathy; laser grid photocoagulation in edematous maculopathy. ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050820
更新日期:1986-11-01 00:00:00
abstract::The relevance of fungal contamination of soft contact lenses is demonstrated by own clinical observations in 25 cases. It can be shown by surface-microscopical, histological and mycological analysis, that various fungi can not only grow on the surface of HEMA-lenses, but can also invade the material. The efficacy of c...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1978-11-01 00:00:00
abstract:INTRODUCTION:Chronic hepatitis C-therapy is limited to the combined use of PEG-ylated interferons and ribavirin. Side effects of this therapy include retinal changes that manifest with bleeding, cotton wool spots and/or thrombosis. PATIENT:A 51-year-old man presented with a sudden decrease of visual acuity. Chronic he...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2004-813607
更新日期:2004-09-01 00:00:00
abstract::In case of keratoconus the epithelial cells are also participating in the pathological processes. Their activity of producing basal membrane is increased. In the stroma four cell types are found; two of them are normal elements. The origin of the two pathological forms is unknown. They may represent as well vagrant ce...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1979-03-01 00:00:00
abstract::The problems of optical correction of unilateral traumatic aphakia are discussed. The treatment of choice is a combined Cataract-operation with intraocular lens implants. The operation must be done as soon as the eye is free of inflammation. Prescription of bifocal glasses in addition to pseudophakoi is necessary. Wit...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 临床试验,杂志文章
doi:
更新日期:1978-04-01 00:00:00
abstract::A total of 369 ophthalmological practices were asked to report the number of patients seen within one test week who drove their cars but did not satisfy minimum legal requirements for diurnal visual acuity applicable for applicants for a West German Class 3 driver's license. There were 471 such patients. From this num...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1054574
更新日期:1984-08-01 00:00:00
abstract::Glaucoma is the leading cause of irreversible blindness in Germany and in the world. Due to the multifactorial genesis of the disease, there are multiple therapeutic approaches for preventing its progression. The goal of the commonly used topical glaucoma medication is to reduce the intraocular pressure and therefore ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/a-1229-1390
更新日期:2020-10-01 00:00:00
abstract::Sometimes the statistical comparison of diagnostic measurement methods or subsequent measurement series in the same individuals is based on bivariate scattergrams; correlation coefficients and linear regression lines are provided in addition. However, this strategy for data representation must be considered inappropri...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2002-35165
更新日期:2002-09-01 00:00:00
abstract::Malignant diseases of the orbit are multifaceted and require in the majority of the cases an interdisciplinary treatment. Advances in radiotherapy, surgery and chemotherapy make a high cure rate possible, especially in children's tumors. In adults these tumors reach a tumor control rate of nearly 90 %, even with prese...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-2004-813821
更新日期:2004-12-01 00:00:00
abstract::Typical visual field defects were found in 86 acute anterior ischemic optic neuropathies occurring in 71 patients. These field defects suggest a separate vascular supply of the upper and lower half of the disc and of the maculo-papillar bundle. A sub-division into four sectors can be inferred in the upper half of the ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1978-07-01 00:00:00
abstract:PURPOSE:The aim of this study was to compare the different calculation methods in large patient collectives, including eyes with extreme axial lengths. METHOD AND MATERIAL:The prediction errors of the Haigis, SRK/T, Hoffer-Q and Holladay formulae and of the OKULIX ray-tracing are compared in 2888 normal eyes implanted...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1027966
更新日期:2009-02-01 00:00:00
abstract:BACKGROUND:The intravitreal injection of an anti-VEGF compound is the current standard of care in neovascular AMD. The response to this therapy varies greatly. To date it was not possible to determine clear predictive factors in regard to therapy response, thus making it difficult when counselling patients regarding th...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0031-1299250
更新日期:2012-04-01 00:00:00
abstract::We report on a 46-year old white male with Norrie disease. In the right eye he had a keratotorus with non vascularized corneal scars and mature cataract. After penetrating keratoplasty a pseudoglioma with irreversible total retinal detachment was found. The left eye had phthisis bulbi with corneal pannus and band kera...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1046058
更新日期:1991-08-01 00:00:00
abstract:BACKGROUND:The comparison of two or more quantitative measurement procedures applied to the same patient is often carried out by unsuitable statistical methods. An orientation for the choice of methods has been given for such problems. METHODS:Graphical methods, the concordance correlation coefficient and some regress...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2006-927278
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:With the discrepancy between availability and demand for corneal donors, the purpose of our study was to identify significant factors influencing the suitability and affecting the main reasons for discarding organ-cultured corneas. We thus aimed to minimise the percentage of unsuitable corneas in...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/a-1141-3703
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:In the treatment of center-involving diabetic macular edema, despite initial therapy with an anti-VEGF compound, an insufficient response may occur. Further therapy options include a switch of anti-VEGF products or to corticosteroid implants, such as Fluocinolone acetonide or Dexamethasone. OBJECTIVES:First...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0043-125076
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Incomplete removal of the viscoelastic material during cataract surgery may lead to the early postoperative capsular block syndrome. In this retrospective case series, postoperative capsular bag distention after implantation of a foldable acrylic lens is reported and the sequelae are analyzed. PATIENTS AND ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2004-812876
更新日期:2004-05-01 00:00:00
abstract:BACKGROUND:The endothelial cell count after phakoemulsification is a sensitive parameter to compare different phakoemulsification techniques. PATIENTS AND METHOD:In a prospective study 30 patients in each group were operated upon the "Reversed Tip and Snip" and with the "Divide and Conquer"-Technique. The corneal endo...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1055/s-2008-1035021
更新日期:1997-02-01 00:00:00
abstract::Botulinum toxin is recognised as the gold standard for the treatment of essential blepharospasm and hemifacial spasm, which is similar in effect in synkinesis after facial nerve palsy. The injection intervals can be adjusted according to the patients' needs and be shortened for up to six weeks in cases of eyelid cramp...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-0042-122339
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:Measles retinitis is rare in immunocompetent patients and has recently been only sporadically described. This case report reveals the clinical picture, the course of the disease and the prognosis of this entity. HISTORY AND FINDINGS:One month after a diagnosed measles infection, a 12-year-old girl presented...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1045509
更新日期:1994-09-01 00:00:00
abstract::Upon utilization of echography one certainly will not be able to detect retinal defects; however, other parameters of retinal detachment which by means of solely optical examination techniques may remain undiagnosed can be evaluated successfully. This concerns not only the diagnosis of retinal detachment alone but als...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1979-03-01 00:00:00
abstract:BACKGROUND:The treatment of late age-related Macular Degeneration (AMD) according to the results of prospective clinical studies is indicated in classical choroidal neovascularisations (NV), which can be delineated from the center of the fovea. To evaluate the effectiveness of this therapy, the knowledge of the frequen...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035324
更新日期:1996-11-01 00:00:00
abstract::From the results of 628 operations on strabismus convergens, the individual corrections were related to the achieved reduction of the angle of deviation. The evaluation showed that strabismus operations may be well dosed not only with a view to a general improvement of the squint angle but also as a specific influence...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1975-08-01 00:00:00
abstract::A large variety of diseases may cause a subretinal neovascularization originating from choroidal vessels. Four cases of parapillary choroidal neovascularisation are described, including neovascularization caused by senile and myopic degeneration, by drusen of the optic nerve head, and by angioid streaks. Obliteration ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050277
更新日期:1988-10-01 00:00:00
abstract:BACKGROUND:Many new diagnostic instruments have been introduced for imaging in ophthalmology, particularly for retinal diseases and diagnostics in glaucoma. The slit lamp, however, as the most important instrument in practical ophthalmological work, has been largely unchanged for decades. It will be shown that a video ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0031-1281765
更新日期:2011-12-01 00:00:00
abstract::A survey is presented of orthoptic exercises practiced over the last 120 years. An attempt is made to deduce attitudes to the exercises from contemporary sensory theories. The currently prevalent nihilistic attitude toward orthoptic training is discussed. ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 历史文章,杂志文章
doi:10.1055/s-2008-1057189
更新日期:1981-03-01 00:00:00