[Botulinum Toxin - New Developments in Ophthalmology].


:Botulinum toxin is recognised as the gold standard for the treatment of essential blepharospasm and hemifacial spasm, which is similar in effect in synkinesis after facial nerve palsy. The injection intervals can be adjusted according to the patients' needs and be shortened for up to six weeks in cases of eyelid cramping. Newer indications for the use of botulinum toxin in ophthalmology include eyelid retraction in Graves' disease, induction of protective ptosis and treatment of crocodile tears syndrome after facial nerve palsy. In future, botulinum toxin may be used in depression (facial feedback), facial injuries and for protection of facial glands against irradiation injury. :Botulinumtoxin ist seit Jahren der Goldstandard bei der Behandlung des essenziellen Blepharospasmus und des Hemispasmus facialis, ähnlich wirksam bei Synkinesien nach Fazialisparese. Falls für den individuellen Patienten erforderlich, können die Injektionsintervalle bei Lidkrämpfen auf bis zu 6 Wochen verkürzt werden. Neuere Indikationen in der Augenheilkunde umfassen die Lidretraktion bei endokriner Orbitopathie, die Induktion einer protektiven Ptosis und die Behandlung von Krokodilstränen. Zukünftig kommt Botulinumtoxin evtl. auch zur Behandlung von Depressionen (facial feedback), von Wunden im Gesichtsbereich und zum Schutz von Drüsen vor Bestrahlungsfolgen in Betracht.


Klin Monbl Augenheilkd


Wabbels B




Has Abstract


2018-06-01 00:00:00












  • [Approaches in medical treatment in glaucoma (author's transl)].

    abstract::The developments concern methods of application and therapeutic agents. Regarding drug aplication Ocusert has to be mentioned: inserted in the cul de sac of the eye once a week it releases a low concentration of a substance continuously and with a constant rate. For acetazolamid (Diamox) it has been shown, that in lon...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章


    authors: Merté HJ

    更新日期:1977-02-01 00:00:00

  • [Enlargement of an extraocular eye muscle: a symptom of cysticercosis].

    abstract:BACKGROUND:Cysticercosis is one of the two infections caused by Taenia solium. It is endemic in areas with poor hygienic standards. In western countries the patients history of previous living or travelling in endemic areas is important. Neurocysticercosis is a manifestation with single or multiple ocular, orbital or c...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章


    authors: Schriever S,Hasenfratz G,Hintschich C,Landau K

    更新日期:1999-11-01 00:00:00

  • [Differential diagnosis of leukokoria in opaque media].

    abstract::In the presence of leukokoria the diagnosis of retinoblastoma is usually easy when the mediae are transparent. If they are not, however, one is frequently obliged to enucleate a painful or useless eye in order to rule out this diagnosis. In a series of eight cases having undergone enucleation for this reason at the La...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章


    authors: Balmer A,Uffer S,Gailloud C

    更新日期:1980-04-01 00:00:00

  • Strabismus Surgery of Consecutive Exotropia.

    abstract:PURPOSE:The purpose of this study was to determine the surgical outcome, dose-effect (DE), and degree of binocularity in patients undergoing surgery for consecutive exotropia following initial surgery of esotropia. PATIENTS/METHODS:Twenty-one patients were identified. We analyzed the mean angle of deviation pre- and p...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章


    authors: Janeschitz-Kriegl L,Roulez F,Wipf MM,Palmowski-Wolfe A

    更新日期:2020-04-01 00:00:00

  • [Ophthalmological symptoms as key findings in neurosyphilis--diagnosis and therapy].

    abstract:BACKGROUND:The incidence of neurosyphilis, one of the late manifestations of syphilis, is reemerging. Affection of the eye is often associated with the disease. It may present with various clinical symptoms, leading to diagnostic difficulties. In cases of early diagnosis and adequate treatment the prognosis of the dise...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章


    authors: Prokosch V,Thanos S,Busse H,Stupp T

    更新日期:2009-03-01 00:00:00

  • [Supportive amblyopia treatment by means of computer games with background stimulation; a placebo controlled pilot study of 10 days].

    abstract:BACKGROUND:Computer programmes for visual stimulation may give new impulses to the field of amblyopia treatment by offering an option to shift the apparative visual training into the domestic sphere. Regarding this aspect we report on a placebo controlled study on a newly developed vision training consisting of a backg...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 临床试验,杂志文章


    authors: Kämpf U,Muchamedjarow F,Seiler T

    更新日期:2001-04-01 00:00:00

  • [Experiences with the hand-held autorefractometer "Retinomax" in adults and children].

    abstract:BACKGROUND:A measurement of ametropia with a table-top mounted autorefractor can be difficult or impossible on children--especially when the children are very young or handicapped. A hand-held autorefractor, however, may be successfully applied in some of these problematic cases. METHODS:Results of comparative measure...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章


    authors: Wesemann W,Dick B

    更新日期:1997-12-01 00:00:00

  • [Optic neuritis].

    abstract::Optic neuritis is a frequent neuro-ophthalmological disease in which the diagnosis can be based on just a few symptoms and findings. It is not only important to differentiate from other optic nerve disorders but also to recognise special types of optic neuritis, which is mostly only possible during the course of the d...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审


    authors: Wilhelm H,Heine C,Tonagel F

    更新日期:2014-11-01 00:00:00

  • Follicular conjunctivitis caused by a mantle cell lymphoma.

    abstract:BACKGROUND:Lymphoma of the conjunctiva as part of a systemic disease is rare. The follicular appearance of the lymphocyte hyperplasia may mimic the clinical picture of infectious or allergic conjunctivitis. We report on a case of marked chronic follicular conjunctivitis, finally diagnosed as mantle cell lymphoma. HIST...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章


    authors: Amstutz CA,Michel S,Thiel MA

    更新日期:2004-05-01 00:00:00

  • [Survival after treatment for malignant choroidal melanoma: comparison between conservative therapy (Ru106/Rh106 applicator) and enucleation with and without postoperative irradiation to the orbit; 1960 to 1979].

    abstract::The survival rate was calculated using the life table method in 1,501 patients suffering from choroidal melanomas and treated in 10 eye hospitals in the GDR between 1960 and 1979. The results of treatment by (1) enucleation, (2) enucleation with postoperative irradiation of the orbit and (3) local irradiation with 106...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章


    authors: Kiehl H,Kirsch I,Lommatzsch P

    更新日期:1984-01-01 00:00:00

  • [Erythropsia following exposure to toluene].

    abstract::A patient who had been exposed to toluol for ten years developed acute erythropsia. The examinations leading to the diagnosis and the possible differential diagnosis are discussed. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章


    authors: Prünte-Glowazki A

    更新日期:1990-05-01 00:00:00

  • [Dexamethason implant in the treatment of macular edema in retinal vein occlusion and intraocular inflammatory disease].

    abstract:BACKGROUND:The efficacy of a single dose of Ozurdex® was evaluated over a 6-month period in eyes with macular edema due to retinal vein occlusion and intraocular inflammatory disease. HISTORY AND SIGNS:20 eyes of 20 consecutive patients with macular edema received a single injection of Ozurdex® (intravitreal dexametha...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 临床试验,杂志文章


    authors: Brunner M,Haueter I,Valmaggia C

    更新日期:2013-04-01 00:00:00

  • [Inflammatory glaucomas].

    abstract::The prevalence of glaucoma in patients with intra- or extraocular inflammation is five to twenty percent. The etiopathogenesis is manifold, including classical secondary open and closed angle mechanisms as well as specific inflammatory elements. Diagnosis and follow-up studies of inflammatory glaucomas are often diffi...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审


    authors: Grüb M,Deuter CM,Zierhut M

    更新日期:2005-10-01 00:00:00

  • [Clinical results of intravitreal administration of tissue-type plasminogen activator (tPA) and gas for removal of subretinal hemorrhage in senile macular degeneration].

    abstract:BACKGROUND:Subretinal hemorrhage in age related macular degeneration (AMD) usually causes acute visual loss and is associated with poor visual prognosis. In order to prevent retinal damage and to perform laser treatment of the underlying choroidal neovascularization (CNV) the subretinal hemorrhage has to be removed fro...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章


    authors: Framme C,Toukhy HE,Sachs HG,Spiegel D,Roider J,Gabel VP,Lohmann CP

    更新日期:2000-01-01 00:00:00

  • [Fusion amplitude and aniseikonia. Experimental studies of aniseikonia tolerance in unilateral aphakia].

    abstract::The fusion amplitude of image pairs with aniseikonia was measured using the synoptophore. Aniseikonia was produced in five subjects by alteration of slide drawings. The subject's right eye was in cycloplegia after paralysis with cycloplegic eye drops. To compare these measurements with aniseikonic pictures to those us...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章


    authors: Pittke EC

    更新日期:1987-12-01 00:00:00

  • [Lysosomal storage diseases - update and new therapeutic options].

    abstract::Lysosomal storage diseases represent a group of about 50 genetic disorders. The deficiencies of lysosomal and non-lysosomal proteins cause an accumulation of compounds which are normally degraded within the lysosome. There are currently no therapeutic options to cure patients suffering from a lysosomal storage disease...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审


    authors: Schöpfer K,Miebach E,Beck M,Pitz S

    更新日期:2011-02-01 00:00:00

  • [Primary therapy of acute angle-block glaucoma].

    abstract::Primary therapeutic measures in 94 eyes suffering from acute angle-closure glaucoma were assessed in a retrospective study. Sixty-eight eyes were treated with acetazolamide, timolol, and pilocarpine. The remaining 26 eyes were treated with acetazolamide and timolol only. The therapy without pilocarpine proved to be si...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章


    authors: Strasser G,Kramsall P

    更新日期:1987-01-01 00:00:00

  • [Assessment of eye damage in private accident insurance in Austria].

    abstract::In Austria, eye damage is assessed by private accident insurance underwriters in accordance with the "General Rules for Private Accident Insurance" (AUVB 1965). According to these rules the degree of invalidity is determined on the basis of three types of findings: 100% in the case of total loss of vision, 30% in the ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章


    authors: Lisch K

    更新日期:1987-05-01 00:00:00

  • [Clinical evaluation of N-acetylaspartylglutamic acid eyedrops in subacute and chronic atopic conjunctivitis].

    abstract::Patients with subacute and chronic atopic conjunctivitis who were treated for at least one year with topically applied 2% sodium cromoglycate 4 times daily were switched to N.A.A.G.A. 6% eye drops for 2 months. A statistically significant gain in treatment effect as assessed objectively (+12.25%) and subjectively (+25...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章


    authors: van Bijsterveld OP,Aalders-Deenstra V

    更新日期:1986-06-01 00:00:00

  • [Biometry of the anterior chamber of the eye in Nd:YAG laser iridectomy].

    abstract::In a prospective clinical study covering 41 eyes (28 patients) with narrow-angle glaucoma the central and peripheral anterior chamber depths were determined biomicroscopically before and after Nd:YAG laser iridectomy. In 29 eyes the central anterior chamber depth was also measured by ultrasonography. In contrast to th...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章


    authors: Schrems W,Hofmann G,Krieglstein GK

    更新日期:1990-03-01 00:00:00

  • [Immunolocalization of fodrin in the retina of vertebrates].

    abstract::Fodrin, a member of the spectrin family, is abundantly found in brain and lens. Based on its often observed peripheral cellular distribution, it is generally believed that fodrin - like other spectrins - participates in the linkage of membrane components to cytoskeletal elements providing their anchorage to distinct, ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章


    authors: Rungger E,Stepanian E,Gilodi N

    更新日期:1991-05-01 00:00:00

  • [The usefulness of echography in retinal surgery (author's transl)].

    abstract::Upon utilization of echography one certainly will not be able to detect retinal defects; however, other parameters of retinal detachment which by means of solely optical examination techniques may remain undiagnosed can be evaluated successfully. This concerns not only the diagnosis of retinal detachment alone but als...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章


    authors: Freyler H

    更新日期:1979-03-01 00:00:00

  • Reattachment of Descemet's membrane using C3F8 gas in an eye with a Baerveldt aqueous shunt.

    abstract::Descemetʼs membrane detachment (DMD) is a rare complication following cataract and glaucoma surgery as well as lamellar graft procedures. DMD can lead to blurry vision, halos and severe visual loss. Clinically, when there is a large central detachment, a double anterior chamber is seen to form. In this scenario, surgi...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章


    authors: Wimmersberger Y,Bergin C,Sharkawi E

    更新日期:2013-04-01 00:00:00

  • ["White dot syndromes" in childhood].

    abstract:BACKGROUND:The term "white dot syndromes" describes a group of heterogeneous inflammatory disorders of the choriocapillaris. They were first described a few decades ago and our knowledge about these variable diseases is very limited, especially in regard to their overall incidence and their differential diagnostic rele...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审


    authors: Spital G,Heiligenhaus A,Scheider A,Pauleikhoff D,Herbort CP

    更新日期:2007-06-01 00:00:00

  • [Use of a new optoelectronic vision aid for highly visually handicapped patients].

    abstract:UNLABELLED:A new low vision aid (LVA)-the Low Vision Enhancement System or LVES, which were as developed at the Johns Hopkins University in Baltimore, is now commercially available. This instrument allows a magnification up to 10 times with control of contrast and luminance while the field of view is very large: 60 x 4...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章


    authors: Rohrschneider K,Bruder I,Aust R,Blankenagel A

    更新日期:1997-02-01 00:00:00

  • [Development and first results of fast and cost-effective examination methods for an ophthalmological screening within the National Cohort].

    abstract:BACKGROUND:For an implemented ophthalmological screening within a German long-term cohort study (National Cohort) simple and effective methods for an examination of visual acuity and for non-mydriatic retina photografies should be evaluated. Furthermore standard operating-procedures (SOP) should be developed. METHODS:...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,多中心研究


    authors: Leitritz MA,Hense HW,Schiefer U,Nagel M,Greiser H,Linseisen J,Heid I,Fischer B,Thierry S,Bartz-Schmidt KU,Ueffing M

    更新日期:2013-12-01 00:00:00

  • [Treatment of herpes simplex keratitis with Vidarabin ointment (author's transl)].

    abstract::In 20 cases of herpes simplex keratitis the efficacy of Vidarabin ointment has been tested, in 19 cases after corneal abrasion. The eyes were treated once a day and padded until the epithelial defects had closed. Thereafter the ointment was applied 4 times per day for about one week more. On the average epithelial clo...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 临床试验,杂志文章


    authors: Egerer I,Drobec P

    更新日期:1978-02-01 00:00:00

  • [Haemoglobin oxygenation of retinal vessels in branch retinal artery occlusions over time and correlation with clinical outcome].

    abstract:OBJECTIVE:Purpose of these study was the evaluation of a new method for the measurement of haemoglobin oxygenation in retinal vessels. Patients with branch retinal artery occlusion have been measured before and after a rheological therapy. METHODS:The haemoglobin oxygenation in retinal vessels was measured by the "oxy...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章


    authors: Gehlert S,Dawczynski J,Hammer M,Strobel J

    更新日期:2010-12-01 00:00:00

  • [Inflammatory and regressive changes of the posterior surface of the cornea].

    abstract::A 52-year-old woman contracted a serious influenza; three weeks later a dropshaped patch, whitish-yellow in color and deeply vascularized, was seen on the posterior upper surface of the cornea of one eye. It was accompanied by an anterior uveitis. The Tyndall phenomenon was positive. The sensibility of the upper quadr...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章


    authors: Welge-Lüssen L,Welt R,Remler B,Demmer HJ

    更新日期:1984-03-01 00:00:00

  • The Distribution of Retinal Venous Pressure and Intraocular Pressure Differs Significantly in Patients with Primary Open-Angle Glaucoma.

    abstract:INTRODUCTION:Until now, venous pressure within the eye has widely been equated with intraocular pressure (IOP). Measurements with dynamometers calibrated in instrument units or in force showed that the retinal venous pressure (RVP) may be higher than the IOP in glaucoma patients. In this study, the RVP was measured wit...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章


    authors: Stodtmeister R,Koch W,Georgii S,Pillunat KR,Spörl E,Pillunat LE

    更新日期:2021-01-12 00:00:00