Abstract:
:Malignant diseases of the orbit are multifaceted and require in the majority of the cases an interdisciplinary treatment. Advances in radiotherapy, surgery and chemotherapy make a high cure rate possible, especially in children's tumors. In adults these tumors reach a tumor control rate of nearly 90 %, even with preservation of the eye in most of the cases. There are only two curative therapy options for tumors in this region: radiotherapy and surgery. The therapy for tumors of the eye and the orbit require the total spectrum of the radiotherapeutic techniques depending on the tumor entity, its spread and localization. In a prevailing number of malignant tumors (tumors of the eyelids, tear glands, orbit, metastases) the application of the radiotherapy as an external, fractionated radiotherapy is standard practice, if necessary in combination with operation and/or chemotherapy. Particularly in the therapy for ocular tumors brachytherapy with radionuclides (e. g., ruthenium) is possible and in a few centers world-wide proton therapy is available. As an alternative procedure in special modalities, stereotactic radiotherapy may be considered. Altogether the new radiotherapy techniques permit a dose increase in the tumor region and/or a reduction of the doses to healthy tissues and lead so to a better local tumor control rate and a decrease in acute and chronic side effects.
journal_name
Klin Monbl Augenheilkdjournal_title
Klinische Monatsblatter fur Augenheilkundeauthors
Kuhnt T,Müller AC,Werschnik C,Janich M,Gerlach R,Dunst Jdoi
10.1055/s-2004-813821subject
Has Abstractpub_date
2004-12-01 00:00:00pages
1033-45issue
12eissn
0023-2165issn
1439-3999journal_volume
221pub_type
杂志文章,评审abstract::The effect of topical administration of Buphenine was studied in a group of aphakic patients (53 eyes). The action of the drug was paradoxical: it induced an increase, often remarkable, in intraocular pressure in more than 70% of the eyes thus treated. The cause of the elevated IOP is discussed. ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1057566
更新日期:1980-05-01 00:00:00
abstract:BACKGROUND:For an implemented ophthalmological screening within a German long-term cohort study (National Cohort) simple and effective methods for an examination of visual acuity and for non-mydriatic retina photografies should be evaluated. Furthermore standard operating-procedures (SOP) should be developed. METHODS:...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,多中心研究
doi:10.1055/s-0033-1350685
更新日期:2013-12-01 00:00:00
abstract::In 40.8% of 169 eyes affected with diabetic preretinopathy (verified by fluorescein angiography) arteriovenous shunt vessels were found. These vessels occur with significant prevalence in eyes with areas of retinal capillary occlusions, and in cases with diabetes of long duration. There is strong evidence that AV shun...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1057587
更新日期:1980-06-01 00:00:00
abstract::Visual evoked potentials (VEP) with checkerboard stimulation are good reference for the function of the visual pathways. Normal VEP are registered from simulants and better than expected VEP are noted from aggravants. However an exact objective determination of the visual acuity is limited, due to the low correlation ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1057538
更新日期:1980-04-01 00:00:00
abstract::A new type of eye speculum is described. It has the following advantages: it does not hamper the surgeon in his work, it has no projecting parts on which sutures may get caught, and it enables spreading of the eyelids to be controlled. ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1975-06-01 00:00:00
abstract::The microioptophoretic injection of PGE1 close to the retinal arterioles procedures a segmental vasodilatation of 40%. The inhibition of prostaglandin synthesis with indomethacin or aspirin blocks the vasodilatatory effect of hypercapnia and, to a lesser extent, of hypoxia. These results suggest that prostaglandins pl...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1978-04-01 00:00:00
abstract:BACKGROUND:The aim of this study was to evaluate retrospectively the clinical outcome of retinal photocoagulation of age-related juxtapapillary choroidal neovascularisation (CNV) with macular oedema. Juxtapapillary CNV represents a rare form of extrafoveal CNV in age-related macular degeneration (AMD). PATIENTS AND ME...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0031-1273430
更新日期:2011-11-01 00:00:00
abstract::Radioactively labelled microspheres (size 15 micron) were used to determine the regional blood flow in cats before and 15, 30 and 45 minutes after unilateral drug administration. In four experimental groups, each consisting of five animals, two drops of the drug were administered into the conjunctival sac. The blood f...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1978-03-01 00:00:00
abstract::An early diagnosis, differential diagnosis and possible decision about therapeutic interventions has considerable consequences for the personal and social life of patients affected with inherited retinal dystrophies (IRD). For the ophthalmologist, the clinical heterogeneity interferes with a simple diagnostic approach...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/a-1118-3705
更新日期:2020-03-01 00:00:00
abstract::Achromatopsia is an autosomal recessive inherited retinal disease caused by a complete loss of cone photoreceptor function. About 80 % of achromatopsia patients show mutations in the alpha or beta subunit (A3 and B3) of the cGMP controlled cation channel CNG (cyclic nucleotide-gated channel) of cone photoreceptors. Ho...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-0034-1368180
更新日期:2014-03-01 00:00:00
abstract::The authors report on the possibilities for examination of the stereoscopic vision at 2 or 4 meters by the phase-difference-haploscope. Besides a gross-qualitative test, methods of estmating realdepth acuity are described. There is a great variability of test-conditions for special scientific problems. During the rout...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1975-09-01 00:00:00
abstract::Critically ill patients in the intensive care unit (ICU) may develop eye problems, due to impaired ocular protective mechanisms or direct involvement of the eye in severe systemic diseases. If eye infections or ocular surface disorders are not identified in time, endophthalmitis or corneal ulcer may develop and can ca...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0042-121806
更新日期:2017-01-01 00:00:00
abstract::A previous double-blind study carried out for 17 weeks on 50 patients with open-angle glaucoma reported on the results of treatment with Timolol and Pilocarpine eye drops. On completion of a long-term study with Timolol over a two-year period, the remaining findings can now be given. Of the 25 patients treated twice a...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 临床试验,杂志文章
doi:
更新日期:1980-11-01 00:00:00
abstract::Biological, rather then purely technical approach seems to be very essential to ensure better results in alloplasty of the cornea. The diseased corneal tissue (especially, after corneal burns) usually fails to accept a keratoprosthesis permanently. The cornea must, therefore, be biologically reconstructed by transplan...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1976-05-01 00:00:00
abstract:PURPOSE:To establish the prevalence, morphological, and functional characteristics and evolution of advanced cases of birdshot retinochoroiditis (BRC). METHODS:A retrospective review of all BRC cases seen at the Centre for Ophthalmic Specialized Care, Lausanne, Switzerland, with at least 3 years of follow-up since the...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/a-1081-1683
更新日期:2020-04-01 00:00:00
abstract::Biologic disease modifying antirheumatic drugs (bDMARDs) can be highly efficient in the treatment of various non-infectious uveitis entities. Currently, the TNF-α-inhibitor Adalimumab is the only in-label therapeutic option, whereas, all other bDMARDs need to be given as an off-label therapy. bDMARDs are indicated in ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/a-0577-8006
更新日期:2018-05-01 00:00:00
abstract:UNLABELLED:In early stages choroidal peripapillary choroidal melanoma may be confused with a choroidal nevus or melanocytoma. CASE REPORT:A 41-year old female was diagnosed having a choroidal nevus in close proximity to the optic nerve head. Unfortunately the patient did not show up for annual review of this lesion. T...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2000-9576
更新日期:2000-12-01 00:00:00
abstract::In a four-year-old boy a malignant teratoid medulloepithelioma of the ciliary body was removed by means of an 11.0 X 11.0 mm "block excision". Two years later the patients visual acuity was 0.6. The lesion originates in the nonpigmented ciliary epithelium, extending along the lens equator to the pupillary zone and thr...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1051036
更新日期:1985-10-01 00:00:00
abstract::Applanation tonometry has been the gold standard in clinical ophthalmology for more than fifty years. The most popular factor is central corneal thickness that is now routinely considered in glaucoma management. However, other individual features of the cornea can also play a key role for the interpretation of the app...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-0029-1246037
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:Most of the presentations concerning quality assurance following cataract surgery are based upon objective data, as it should be. But the success of an eye-clinic is not limited by such objective data, but on the contentment of the patients and the local colleagues, who direct the patients. Our aim in the fo...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035305
更新日期:1996-10-01 00:00:00
abstract::In 22 open-angle glaucoma patients a total of 39 eyes were treated with Timolol 0.25% twice daily for an average period of 12.6 months. The relative intraocular pressure decrease at the beginning of the study was 47% of the untreated pressure level. This initial response declined to a 23% pressure decrease at the end ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1979-11-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy of an intravitreal dexamethasone implant (Ozurdex®) in patients with cystoid macular oedema (CME) suffering from non-infectious uveitis. METHODS:Monocentric, retrospective, single-arm analysis in 49 patients (59 implanted eyes) with inactive uveitis, in whom CME had been unresponsive t...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0042-102058
更新日期:2016-05-01 00:00:00
abstract::This report covers 310 patients with concomitant convergent strabismus and anomalous retinal correspondence. In 36 cases tenomyotomy alone was responsible for normalization of correspondence. This is best achieved in cases of bilateral converging strabismus without vertical divergence. ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1979-08-01 00:00:00
abstract::An endogenous endophthalmitis is a severe, potentially blinding intraocular infection due to haematogenous spread of germs. In Europe, gram-positive bacteria and Candida albicans are common causative organisms. Compared to post-operative cases of endophthalmitis, endogenous endophthalmitis is relatively rare, accounti...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-2008-1027611
更新日期:2008-11-01 00:00:00
abstract:BACKGROUND:Many new diagnostic instruments have been introduced for imaging in ophthalmology, particularly for retinal diseases and diagnostics in glaucoma. The slit lamp, however, as the most important instrument in practical ophthalmological work, has been largely unchanged for decades. It will be shown that a video ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0031-1281765
更新日期:2011-12-01 00:00:00
abstract:OBJECTIVE:To study the learning risk of a new surgical technique, the deep sclerectomy (DS), which may be complicated with a perforation of the trabeculodescemetic membrane. To do so, we compared the results and the complications of patients who underwent DS transformed in trabeculectomy (DSt) and those of patients who...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035050
更新日期:1997-05-01 00:00:00
abstract:BACKGROUND:In the city of Zurich, vision screening is performed by school medical services as part of the legally compulsory preventive medical examinations. We retrospectively evaluated the results of the 2011-2012 school year. PATIENTS AND METHODS:Preventive medical examinations by the school medical services were p...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0041-111818
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:Dilated episcleral vessels may be observed in patients with orbital tumors, carotid-cavernous-sinus fistula and other orbital obstructive lesions. As an idiopathic phenomenon dilated episcleral vessels may be associated with secondary open-angle glaucoma. PATIENT:We report on a 59-year-old patient with a hi...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035110
更新日期:1997-08-01 00:00:00
abstract:PURPOSE:The purpose of this study was to assess the vasoconstrictor effect of the prostaglandin F2 alpha analog latanoprost in isolated porcine ciliary arteries. MATERIAL AND METHODS:With a myograph system to measure isometric forces, porcine ciliary arteries were exposed, in a cumulative manner, to increasing concent...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2001-15904
更新日期:2001-05-01 00:00:00
abstract:OBJECTIVE:Purpose of these study was the evaluation of a new method for the measurement of haemoglobin oxygenation in retinal vessels. Patients with branch retinal artery occlusion have been measured before and after a rheological therapy. METHODS:The haemoglobin oxygenation in retinal vessels was measured by the "oxy...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0029-1245117
更新日期:2010-12-01 00:00:00