Hemodynamic alterations in focal cerebral ischemia: temporal correlation analysis for functional imaging.

abstract：:Cyclic GMP (cGMP) mediates smooth muscle relaxation in the central nervous system. In subarachnoid hemorrhage (SAH), decreases in intrinsic nitric oxide (NO) cause cerebral vasospasms due to the regulation of cGMP formation by NO-mediated pathways. As phosphodiesterase type V (PDE V) selectively hydrolyzes cGMP, we hy...

journal_title：Neurological research

authors： Inoha S,Inamura T,Ikezaki K,Nakamizo A,Amano T,Fukui M

更新日期：2002-09-01 00:00:00

abstract：:In order to evaluate the relationship between brain oxygen supply and demand (O2 balance) in real time, it is necessary to use a multiparametric monitoring approach. Cerebral blood flow (CBF) is a representative parameter of O2 supply. The extracellular level of K+ is a reliable indicator of O2 demand since more than ...

journal_title：Neurological research

authors： Mayevsky A,Meilin S,Manor T,Ornstein E,Zarchin N,Sonn J

更新日期：1998-01-01 00:00:00

abstract：:Cerebral blood flow (CBF), 113mIndium-DPTA, and 14C-glucose extraction were measured simultaneously in rat brain from 2 to 58 days following a thermal insult. In the early stage of a cold induced lesion (2 days), the blood-brain barrier (BBB) was disrupted with resulting leakage and diffusionary loss of both glucose a...

journal_title：Neurological research

authors： Pollay M,Stevens FA

更新日期：1980-01-01 00:00:00

abstract：:Synthesized Mn-TPPS, a paramagnetic metalloporphyrin, is expected to be a tumour specific contrast media for magnetic resonance (MR) imaging. We investigated the enhancing characteristics of Mn-TPPS using a transplanted rat C6 glioma model with peripheral type benzodiazepine (PBD) receptors since porphyrins are though...

journal_title：Neurological research

authors： Ikezaki K,Nomura T,Takahashi M,Fritz-Zieroth B,Inamura T,Fukui M

更新日期：1994-10-01 00:00:00

abstract：:Intracerebral hemorrhage (ICH) remains a major medical problem, for which there is no effective treatment. However, extensive experimental and clinical research carried out in recent years has brought to light new exciting ideas for novel potential treatments. First, it was well documented that the management of hyper...

journal_title：Neurological research

authors： Aronowski J,Hall CE

更新日期：2005-04-01 00:00:00

abstract：:Recent evidence indicates that different vascular risk factors are present in Alzheimer's disease (AD) and other prevalent dementia types probably contributing to deterioration of cerebrovascular function, thus enhancing neurodegeneration and premature neuronal death due to a reduction in brain perfusion. Brain blood ...

journal_title：Neurological research

authors： Cacabelos R,Fernández-Novoa L,Lombardi V,Corzo L,Pichel V,Kubota Y

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVE:The unified Parkinson's disease rating scale (UPDRS) is the most widely used tool to rate the severity and the stage of Parkinson's disease (PD). However, the mentation, behavior and mood (MBM) subscale of the UPDRS has received little investigation regarding its validity and sensitivity. Three items of this ...

journal_title：Neurological research

authors： Holroyd S,Currie LJ,Wooten GF

更新日期：2008-06-01 00:00:00

abstract：:We studied brain temperature and the effect of mild hypothermia in 58 patients after severe head injury (SHI). Brain tissue oxygen tension (ptiO2), carbon dioxide tension (ptiCO2), tissuie pH (pHti) and temperature (T.br) were measured using a multiparameter probe. Microdialysis was performed to measure glucose, lacta...

journal_title：Neurological research

authors： Soukup J,Zauner A,Doppenberg EM,Menzel M,Gilman C,Bullock R,Young HF

更新日期：2002-03-01 00:00:00

abstract：:Although rat models implanted with C6 glioma cells have been widely utilized for the assessment of new therapeutic modalities, a convenient in vivo model is still required. We implanted C6 glioma cells into the brains and the abdominal subcutaneous regions of Wistar rats, and evaluated the volumes of the growing tumor...

journal_title：Neurological research

authors： Watanabe K,Sakamoto M,Somiya M,Amin MR,Kamitani H,Watanabe T

更新日期：2002-07-01 00:00:00

abstract：:Recent publications have suggested that intra-ocular pressure (IOP) may be an indirect assessment of intra-cranial pressure (ICP). Both IOP and ICP have similar physiologic pressure ranges and similar responses to changes in intra-abdominal, intra-thoracic and aortic pressure. Previous studies have demonstrated the re...

journal_title：Neurological research

authors： Dickerman RD,Smith GH,Langham-Roof L,McConathy WJ,East JW,Smith AB

更新日期：1999-04-01 00:00:00

abstract：:Objective: Remote limb ischemic postconditioning (RIPostC) protects the brain from damage induced by transient focal ischemia/reperfusion. However, the underlying mechanism remains unclear. Methods: RIPostC induced by 10 min of occlusion and another 10 min releasing of blood flow for three cycles in the hind limbs was...

journal_title：Neurological research

authors： Liu C,Yang J,Zhang C,Geng X,Zhao H

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVES:In conditions with reduced glucose levels/inability of glucose utilization, ketone bodies, especially beta-hydroxybutyrate (BHB), become a major energy source in the brain. In animal models, BHB infusion shows acute beneficial effects on the hypoxic brain. The present prospective observational study is the f...

journal_title：Neurological research

authors： Pikija S,Trkulja V,Simundic AM,Vrcek E,Boskovic K,Bacani S

更新日期：2013-11-01 00:00:00

abstract：:Predictions from a structured cortical model led us to test the hypothesis that music training enhances young children's spatial-temporal reasoning. Seventy-eight preschool children participated in this study. Thirty-four children received private piano keyboard lessons, 20 children received private computer lessons, ...

journal_title：Neurological research

authors： Rauscher FH,Shaw GL,Levine LJ,Wright EL,Dennis WR,Newcomb RL

更新日期：1997-02-01 00:00:00

abstract：:Analysis of the blood flow velocities in the middle cerebral artery by transcranial Doppler ultrasonography was performed in 158 healthy volunteers (aged 14-70 years; 82 men and 76 women). In a subgroup of 38 men and 21 women the end-tidal [CO2] was also measured. The influence of biological factors such as age, sex, ...

journal_title：Neurological research

authors： Ackerstaff RG,Keunen RW,van Pelt W,Montauban van Swijndregt AD,Stijnen T

更新日期：1990-09-01 00:00:00

abstract：:Acute blood-brain barrier (BBB) opening in cerebral ischemia is an often observed but seldom studied phenomenon. Increased permeability has been implicated with several consequences including exacerbating ischemic injury, leading to hemorrhagic transformation (HT) and also predictive of chronic damage and a way of del...

journal_title：Neurological research

authors： Nagaraja TN,Keenan KA,Brown SL,Fenstermacher JD,Knight RA

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:To explore the primary regularity of cerebral electrical impedance (CEI) change in healthy people, patients with intracerebral hemorrhage (ICH) and patients with cerebral infarction (CI). METHODS:CEI of 200 healthy volunteers, 78 patients with ICH and 51 patients with CI were measured by noninvasive brain-ed...

journal_title：Neurological research

authors： Liu L,Dong W,Ji X,Chen L,Chen L,He W,Jia J

更新日期：2006-01-01 00:00:00

abstract：:This study comprises scientific-theoretic fundamental investigations of laserneedle technology, a new and painless method of acupuncture stimulation. Laserneedles are not inserted in the skin, but are merely placed on the surface of the acupuncture point. The study documents the significant changes in peripheral micro...

journal_title：Neurological research

authors： Litscher G

更新日期：2003-10-01 00:00:00

abstract：:We assessed the effect of a novel calmodulin antagonist, DY-9760e (3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate) in a spontaneously hypertensive rat (SHR) permanent focal cerebral ischemia. In experiment I, the left middle cerebral ...

journal_title：Neurological research

authors： Takagi K,Sato T,Shirasaki Y,Narita K,Tamura A,Sano K

更新日期：2001-09-01 00:00:00

abstract：:We elected to compare the clinical outcomes of carotid endarterectomy (CEA) patients who were thought to be at increased risk for peri-operative complications because of advanced age (> 79 years), medical comorbidities and contralateral internal carotid artery occlusion to patients without these risk factors. A prospe...

journal_title：Neurological research

authors： Harbaugh RE,Magnadottir HB

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:Recurrent lumbar disc herniation (rLDH) is a common issue after primary discectomy and can cause severe pain, morbidity, and reoperation. The purpose of this systematic review was to evaluate the surgical management of recurrent lumbar disc herniation. METHODS:A systematic literature search was conducted usi...

journal_title：Neurological research

authors： Arif S,Brady Z,Enchev Y,Peev N

更新日期：2020-12-01 00:00:00

abstract：:Coupling of neuronal activity to cerebral blood flow (CBF) is widely accepted, but the exact mechanism is still under investigation. We assessed the responses of CBF coupled with electrical activity over the primary somatosensory cortex (S-I) during electrical stimulation of the contralateral forearm in cats. CBF in S...

journal_title：Neurological research

authors： Ichimi K,Kuchiwaki H,Inao S,Shibayama M,Yoshida J

更新日期：1999-09-01 00:00:00

abstract：:Although the circulation of cerebrospinal fluid enjoys an apparent simplicity, its underlying basis is amazingly complex. Many factors influence how CSF flows through the human central nervous system. In the presence of hydrocephalus and subsequent shunt placement, this system is further complicated. The challenge bef...

journal_title：Neurological research

authors： Magram G,Liakos AM

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:Surgical resection of complex glomus vagale tumors can be complicated by extensive blood loss and might require surgical sacrifice of an encased internal carotid artery. METHODS:A young patient presented with mass effect from glomus valage tumor. Computerized tomography angiography showed an encased interna...

journal_title：Neurological research

authors： Alaraj A,Pytynia K,Carlson AP,Krishna PH,Charbel FT,Amin-Hanjani S,Aletich V

更新日期：2012-07-01 00:00:00

abstract：:Despite the accumulation of intraoperative data on arteriovenous malformations (AVMs), details of the haemodynamics have not yet been elucidated. A hydraulic model was constructed from silicone and glass tubes to simulate a high-flow AVM. During stepwise obliteration of the nidus, haemodynamic changes were continuousl...

journal_title：Neurological research

authors： Nagasawa S,Kawanishi M,Tanaka H,Ohta T,Nagayasu S,Kikuchi H

更新日期：1993-12-01 00:00:00

abstract：:The relationship between the states of spinal impact injuries and magnetically evoked electromyograms (EMGs) were studied in rats. Impact injuries to the spinal cord were induced at a depth of 0.25-2.0 mm by insertion of a cylinder tip measuring 2 mm in diameter into the lumbar vertebrae L1-L2. Magnetically induced el...

journal_title：Neurological research

authors： Chiba A,Hiruma S,Hashimoto S,Inase M

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVES:Transient ischemic attack (TIA) with carotid artery disease (CAD) can increase the risk of cognitive decline. However, the neural mechanisms of the disorder remain unclear. The aim of this study was, using diffusion tensor imaging (DTI), to detect microstructural changes in patients with symptomatic CAD pres...

journal_title：Neurological research

authors： Guo J,Wang S,Li R,Chen N,Zhou M,Chen H,Gong Q,He L

更新日期：2014-01-01 00:00:00

abstract：:The possible role of nitric oxide (NO) on vibrissa-stimulated increase of regional cerebral cerebral blood flow (rCBF) and cerebral metabolic rate of glucose (rCMRglu) was investigated in conscious Wistar rats by using an inhibitor of NO synthase, NG-nitro-L-arginine (NOLAG) at a concentration of 30 mg/kg. In vivo aut...

journal_title：Neurological research

authors： Wang Q,Kjaer T,Jørgensen MB,Paulson OB,Lassen NA,Diemer NH,Lou HC

更新日期：1993-02-01 00:00:00

abstract：OBJECTIVES:The stroke-prone spontaneously hypertensive rat is a genetic model of severe hypertension with secondary vascular alterations. The aim of this study was to determine the influence of chronic hypertension and ramipril treatment on the extracellular matrix in the cerebral microvasculature. METHODS:The study c...

journal_title：Neurological research

authors： Liebetrau M,Burggraf D,Büscher C,Linz W,Hamann GF

更新日期：2005-07-01 00:00:00

abstract：:Background Transtemporal Doppler (TTD) with middle cerebral artery (MCA) is widely used for right-to-left shunt (RLS) detection. However, an alternative method for patients without suitable temporal bone windows should be established. The present study prospectively evaluated the effectiveness of transorbital Doppler ...

journal_title：Neurological research

authors： Duan Z,Yang Z,Song B,Ma C,Li Y,Du Y,Shang D,Li S,Lou J

更新日期：2018-03-01 00:00:00

abstract：:The frequency of skull metastasis from hepatocellular carcinoma (HCC) is increasing together with the recent progress in the management of the primary lesion. Cases are often complicated with poor general conditions or metastasis to the other organs, and not readily indicated for surgery. A direct injection of ethanol...

journal_title：Neurological research

authors： Isaka T,Yoshimine T,Fujimoto K,Masuzawa M,Maruno M,Hayakawa T,Nakatani S

更新日期：1998-12-01 00:00:00