Ramipril prevents extracellular matrix accumulation in cerebral microvessels.

abstract：:Fifteen patients with symptoms of cerebral ischaemia and angiographically confirmed unilateral stenoses or occlusions of the extracranial internal carotid artery (ICA) and 20 controls were studied by a 2 MHz transcranial Doppler (TCD) at rest and after stimulation with 1 g acetazolamide i.v., a cerebral vasodilator. I...

journal_title：Neurological research

authors： Rosenkranz K,Hierholzer J,Langer R,Hepp W,Palenker J,Felix R

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:This review will describe the novel contributions to the field of nerve repair from the emerging disciplines of microtechnology and nanotechnology. METHOD:This broad review will cover the advances described in the literature of the medical and biological fields and the engineering and physical sciences. The ...

journal_title：Neurological research

authors： Chang WC,Kliot M,Sretavan DW

更新日期：2008-12-01 00:00:00

abstract：:The influence of acidic fibroblast growth factor (aFGF) on sleep was studied in conscious rabbits. An intravenous (i.v.) bolus injection of aFGF induced a significant increase in sleep duration in comparison with animals that received vehicle solution. Somnogenic effects were obtained 30 min following i.v. aFGF admini...

journal_title：Neurological research

authors： Galan JM,Cuevas B,Dujovny N,Giménez-Gallego G,Cuevas P

更新日期：1996-12-01 00:00:00

abstract：OBJECTIVES:4-N-trimethylammonium-3-hydroxybutyric acid (L-carnitine) is an endogenous mitochondrial membrane compound and some studies have reported that L-carnitine could effectively protect various cells against oxidative injury both in vitro and in vivo. In the present study, we used the human neuroblastoma SH-SY5Y ...

journal_title：Neurological research

authors： Yu J,Ye J,Liu X,Han Y,Wang C

更新日期：2011-09-01 00:00:00

abstract：:Thromboxane A2 (TXA2) is a proaggregatory vasoconstrictor that is synthesized and released during reperfusion of ischaemic brain. We administered a TXA2 receptor antagonist, SQ29,548, and a thromboxane A synthase inhibitor, 1-benzylimidazole (1-BI), to rats subjected to 30 min of reversible forebrain ischaemia. Cerebr...

journal_title：Neurological research

authors： Pettigrew LC,Hazle JD,Gutierrez G,Smith CD,Ogletree ML

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:High blood pressure (BP) is a major risk factor for stroke and all of its pathological subtypes including subarachnoid hemorrhage (SAH). However, there is little evidence demonstrating whether failure to have regular BP measured could result in underestimation of people at risk for SAH. Therefore, we aimed ...

journal_title：Neurological research

authors： Shiue I,Hankey GJ,Arima H,Anderson CS

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVES:The syntheses of endothelin receptors A and B were previously shown to be upregulated in rat dorsal hippocampus after traumatic brain injury. Here we characterize endothelin receptor A and endothelin receptor B cellular distribution in hippocampus after permanent global brain ischemia and their possible asso...

journal_title：Neurological research

authors： Kreipke CW,Reynolds CA,Schafer PC,Schafer S,Pirooz R,Rafols JA

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVES:The presence of beta-amyloid (betaA) deposition, induction of reactive gliosis and dystrophic neurites, is a characteristic feature of neuritic plaques in Alzheimer's disease. In vitro, betaA-exposed astrocytes become reactive, similar to astrocytes in contact with betaA plaques in vivo. How betaA-exposed re...

journal_title：Neurological research

authors： Monnerie H,Esquenazi S,Shashidhara S,Le Roux PD

更新日期：2005-07-01 00:00:00

abstract：:In order to investigate the role of the endothelium in the regulation of cerebrovascular tone, we studied selective intraluminal and extraluminal vasoactive mechanisms of acetylcholine, potassium and serotonin. We also examined the effects of removal of the endothelium on these vasoactive responses. With 0.75 g of ten...

journal_title：Neurological research

authors： Ogawa R,Ohta T,Tsuji M,Mori M

更新日期：1993-06-01 00:00:00

abstract：INTRODUCTION:Here, we investigated inflammatory signs of peripheral nerves in leptin-deficient obese ob/ob mice and the modulating effects of the exogenous iron load. METHODS:Ob/ob and ob/+ control mice were fed with high, standard, or low iron diet for four months. RESULTS:We found intraepidermal nerve fiber degener...

journal_title：Neurological research

authors： Kosacka J,Woidt K,Toyka KV,Paeschke S,Klöting N,Bechmann I,Blüher M,Thiery J,Ossmann S,Baum P,Nowicki M

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:Repetitive magnetic stimulation (rMS) is mainly used in transcranial applications. Only a few works have described its potential peripheral use. The aim of this investigation was to determine if conditioning peripheral (paravertebral) rMS of the cervical nerve roots in a group of healthy subjects induces chan...

journal_title：Neurological research

authors： Krause P,Straube A

更新日期：2008-09-01 00:00:00

abstract：:At present, no practical method exists for monitoring the progression and severity of cerebral oedema in a clinical setting on a continuous basis. In search for such a method, we investigated the electrical characteristics of cerebral tissue at microwave frequencies to quantify cerebral oedema. The dielectric constant...

journal_title：Neurological research

authors： Kramer GG,Cardoso ER,Shwedyk E

更新日期：1992-06-01 00:00:00

abstract：OBJECTIVES:To estimate the incidence of cognitive impairment (CI) among cognitively healthy, Mexican subjects, and to evaluate the impact of demographic and vascular factors on the conversion to CI and mortality. METHODS:734 eligible subjects (aged 55 to >90 years) from a population-based sample were examined. The cog...

journal_title：Neurological research

authors： Arauz A,Alonso E,Rodríguez-Saldaña J,Reynoso-Marenco M,Benitez IT,Mayorga AM,Rodríguez-Agudelo Y,Romero AV,Cantú C

更新日期：2005-12-01 00:00:00

abstract：:Regional glucose utilization was measured in the rat brain after occlusion of the middle cerebral artery. Normoglycaemic rat had increased glucose use in the cerebral cortex adjacent to the infarct. A fraction of the nerve cells were irreversibly injured in this region. In hyperglycaemic rats, the glucose metabolism r...

journal_title：Neurological research

authors： Nedergaard M,Gjedde A,Diemer NH

更新日期：1987-12-01 00:00:00

abstract：:Decreased metabolic rate may precede cognitive impairment in Alzheimer's disease (AD) and is thus an early occurring hallmark. Several observations in post-mortem brain indicate that activated neurons are better able to withstand aging and AD, a phenomenon paraphrased by us as 'use it or lose it'. Moreover, a number o...

journal_title：Neurological research

authors： Swaab DF

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:It is necessary to understand the mechanism of trigeminal neuralgia (TN) and hemifacial spasm (HFS) in order to seek for an effective noninvasive remedy. As previous studies implied that inflammatory cytokines induced by demyelination following the nerve injury may be the initiated factor causing neuropathic...

journal_title：Neurological research

authors： Liu MX,Zhong J,Xia L,Dou NN,Li ST

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:Diabetes is one of the major risk factors for ischemic stroke and is reported to aggravate the ischemic brain damage in different experimental models as well as clinical situations. However, the mechanisms underlying the exacerbated ischemia/reperfusion (I/R) brain injury associated with comorbid diabetes ar...

journal_title：Neurological research

authors： Srinivasan K,Sharma SS

更新日期：2011-10-01 00:00:00

abstract：INTRODUCTION:Numerous studies have demonstrated a protective effect of hyperbaric oxygen therapy in experimental ischemic brain injury, and many physiological and molecular mechanisms of hyperbaric oxygen therapy-related neuroprotection have been identified. METHODS:Review of articles pertaining to hyperbaric oxygen t...

journal_title：Neurological research

authors： Matchett GA,Martin RD,Zhang JH

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVES:To describe the role of neurosurgical techniques in treatment of symptoms of multiple sclerosis (MS). METHODS:A review of the existing world literature searching (using PubMed, August 22, 2005) for key words 'multiple sclerosis' and multiple symptoms associated with MS including trigeminal neuralgia, pain (...

journal_title：Neurological research

authors： Patwardhan RV,Minagar A,Kelley RE,Nanda A

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVE:Music-supported therapy (MST) is a new approach for motor rehabilitation of stroke patients. Recently, many studies have demonstrated that MST improved the motor functions of post-stroke patients. However, the underlying mechanism for this effect is still unclear. It may result from repeated practice or repea...

journal_title：Neurological research

authors： Tong Y,Forreider B,Sun X,Geng X,Zhang W,Du H,Zhang T,Ding Y

更新日期：2015-05-01 00:00:00

abstract：:Thirty outpatients with unruptured cerebral aneurysms screened by computed angiotomography have been analysed and followed up in our clinic since 1979. Seventeen were men and the age range was 41 to 74 years old (mean 57.7 years). Patients had no or only mild neurological symptoms, such as headache, sensorimotor or sp...

journal_title：Neurological research

authors： Yamamoto Y,Asari S,Sunami N,Kunishio K,Fukui K,Sadamoto K

更新日期：1986-06-01 00:00:00

abstract：:The craniocervical regions of seven cadavers (14 sides) injected with silicone rubber were dissected under a Zeiss OPMI surgical microscope. The present study provides a detailed description of the suboccipital segment of the vertebral artery, with particular attention to its loops, branches, supporting osteofibrous s...

journal_title：Neurological research

authors： Castillo C,Viñas FC,Gutikhonda M,Diaz FG

更新日期：1998-04-01 00:00:00

abstract：:Magnetic resonance (MR) is a powerful new imaging modality which has recently become competitive with X-ray computed tomography (CT) for imaging of the central nervous system (CNS). The advantages of MR include lack of ionizing radiation and the necessity to use iodinated contrast. MR is able to image directly in the ...

journal_title：Neurological research

authors： Bradley WG Jr

更新日期：1984-09-01 00:00:00

abstract：OBJECTIVES:Our objective was to characterize the heat shock response (HSR) in a model of traumatic brain injury (TBI) and to determine the association of HSR to cell death. METHODS:We used immunofluorescent detection of HSP-70 to characterize HSR and TUNEL labeling to determine the pattern of cell death. RESULTS:HSP-...

journal_title：Neurological research

authors： DeGracia DJ,Kreipke CW,Kayali FM,Rafols JA

更新日期：2007-06-01 00:00:00

abstract：:Predictions from a structured cortical model led us to test the hypothesis that music training enhances young children's spatial-temporal reasoning. Seventy-eight preschool children participated in this study. Thirty-four children received private piano keyboard lessons, 20 children received private computer lessons, ...

journal_title：Neurological research

authors： Rauscher FH,Shaw GL,Levine LJ,Wright EL,Dennis WR,Newcomb RL

更新日期：1997-02-01 00:00:00

abstract：OBJECTIVES:The purpose of this study is to use diffusion tensor imaging (DTI) parameters to evaluate cerebral ischemia/reperfusion injury in the infarct core (IC) and ischemic penumbra (IP) in a rhesus transient middle cerebral artery occlusion (MCAO) model. METHODS:Seven rhesus monkeys were used to construct the MCAO...

journal_title：Neurological research

authors： Guo J,Zheng HB,Duan JC,He L,Chen N,Gong QY,Tang HH,Li HX,Wang L,Cheng JQ

更新日期：2011-01-01 00:00:00

abstract：:The present study was designed to investigate the beneficial effects of cornel iridoid glycoside (CIG), a main component extract from Cornus officinalis, on neurotrophin expression in mouse experimental autoimmune encephalomyelitis (EAE), a classical model of multiple sclerosis (MS). After EAE initiation, CIG was intr...

journal_title：Neurological research

authors： Qu Z,Zheng N,Zhang Y,Zhang L,Liu J,Wang Q,Yin L

更新日期：2016-09-01 00:00:00

abstract：:Ahead of Print article withdrawn by publisher. ...

journal_title：Neurological research

authors： Ma CX,Yin WN,Cai BW,He M,Wu J,Wang JY,Zeng Y,Ding JL,You C

更新日期：2009-08-21 00:00:00

abstract：INTRODUCTION:Alteration of sensorium or an encephalopathy is a common diagnostic dilemma in critically ill patients and can be caused by a number of conditions. Sepsis associated encephalopathy (SAE) is now the most common encephalopathy encountered among intensive care unit (ICU) patients. DEFINITIONS:SAE is an encep...

journal_title：Neurological research

authors： Maramattom BV

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVES:Amyloid-beta (Aβ) peptide deposition into insoluble plaques is a pathological hallmark of Alzheimer's disease (AD), but soluble oligomeric Aβ is considered to be more potent and has been hypothesized to directly impair learning and memory. Also, evidences from some clinical studies indicated that Aβ oligomer...

journal_title：Neurological research

authors： Sharma S,Verma S,Kapoor M,Saini A,Nehru B

更新日期：2016-09-01 00:00:00