Cerebrospinal fluid flow through an implanted shunt.

abstract：:We describe the use of optical spectroscopy in the near infra-red light range to non-invasively measure regional cerebral haemoglobin oxygen saturation (rSHbO2) in cats during progressive cerebral hypoxia. This technique differs from spectroscopic techniques previously described in that the concentration ratio--percen...

journal_title：Neurological research

authors： McCormick PW,Stewart M,Ray P,Lewis G,Dujovny M,Ausman JI

更新日期：1991-03-01 00:00:00

abstract：:Basic fibroblast growth factor (bFGF) possesses neuroprotective effects on a variety of neurons. Here we report that it delays progression of motor neuron disease (MND) in the wobbler mouse. After initial diagnosis of MND at post-natal age 3-4 weeks, wobbler mice receive either recombinant human bFGF (1 mg kg-1, n = 1...

journal_title：Neurological research

authors： Ikeda K,Iwasaki Y,Tagaya N,Shiojima T,Kobayashi T,Kinoshita M

更新日期：1995-12-01 00:00:00

abstract：:The application of optical spectroscopy for intra-operatively delineating brain tumors has been studied in this paper. The classification of tissue as normal, tumor and boundary is done using the LAMSTAR neural network (NN). The objective is to combine both fluorescence and reflectance as attributes to be used for the...

journal_title：Neurological research

authors： Sivaramakrishnan A,Graupe D

更新日期：2004-09-01 00:00:00

abstract：:In addition to its possible role as a replacement source in CNS degenerative diseases, neural transplantation may be used to augment the normal production of neuroactive substances. Our laboratory at the University of Illinois at Chicago has shown, in both acute and chronic pain models, that transplantation of adrenal...

journal_title：Neurological research

authors： Pappas GD,Lazorthes Y,Bès JC,Tafani M,Winnie AP

更新日期：1997-02-01 00:00:00

abstract：:Microsurgical anatomy for the pterional approach was studied regarding the origin and the course of the ophthalmic artery and the distal dural ring using human cadaveric specimens, with special reference to the surrounding bony structures. In 50 human adult formalin-fixed cadaveric cerebral hemispheres and 10 block sp...

journal_title：Neurological research

authors： Hokama M,Hongo K,Gibo H,Kyoshima K,Kobayashi S

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVES:The stroke-prone spontaneously hypertensive rat is a genetic model of severe hypertension with secondary vascular alterations. The aim of this study was to determine the influence of chronic hypertension and ramipril treatment on the extracellular matrix in the cerebral microvasculature. METHODS:The study c...

journal_title：Neurological research

authors： Liebetrau M,Burggraf D,Büscher C,Linz W,Hamann GF

更新日期：2005-07-01 00:00:00

abstract：INTRODUCTION:Neurotoxic homocysteine (Hcy) is thought to be an independent risk factor for neurodegenerative diseases, including Alzheimer's disease. This study is to determine whether HT22 cells, a murine hippocampal neuronal model, can be used as an in vitro model, besides the primary neuronal cultures, to investiga...

journal_title：Neurological research

authors： Zhao Z,Lu R,Zhang B,Shen J,Yang L,Xiao S,Liu J,Suo WZ

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVES:Susceptibility-weighted (SW) magnetic resonance (MR) imaging is a sensitive test to detect intravenous deoxygenated blood. On SW images, dilated appearing draining veins in tissue with perfusion impairment occur due to an increase in intravenous deoxyhemoglobin levels, and could indicate poor perfusion areas...

journal_title：Neurological research

authors： Sorimachi T,Morita K,Sasaki O,Koike T,Fujii Y

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:To assess the effect of sensory nerve stimulation in older people with peripheral neuropathy associated with diabetes (DPN). MATERIALS AND METHODS:A randomized, placebo controlled, double blind trial was used to assess the effect of 12 weeks of low frequency sensory nerve stimulation (LF-SNS) in the lower li...

journal_title：Neurological research

authors： Khalil Z,Ogrin R,Darzins PJ

更新日期：2007-10-01 00:00:00

abstract：:The possible role of nitric oxide (NO) on vibrissa-stimulated increase of regional cerebral cerebral blood flow (rCBF) and cerebral metabolic rate of glucose (rCMRglu) was investigated in conscious Wistar rats by using an inhibitor of NO synthase, NG-nitro-L-arginine (NOLAG) at a concentration of 30 mg/kg. In vivo aut...

journal_title：Neurological research

authors： Wang Q,Kjaer T,Jørgensen MB,Paulson OB,Lassen NA,Diemer NH,Lou HC

更新日期：1993-02-01 00:00:00

abstract：:The possibility of the evaluation of ischemia solely by the momentary values of regional cerebral blood flow (rCBF) was investigated. Ischaemic damage was evaluated histopathologically and by observing albumin extravasation. Unilateral carotid clippings were performed for 1 h and the gerbils evaluated with regard to t...

journal_title：Neurological research

authors： Kadota E

更新日期：1988-12-01 00:00:00

abstract：OBJECTIVE:Meningiomas are benign intracranial tumors growing from the arachnoid cap cells. Although their behavior is usually benign, they tend to recur even after total removal, and their recurrence is dependent on different aspects. METHODS:Between 1991 and 2002, 463 patients with an intracranial meningioma were ope...

journal_title：Neurological research

authors： Strassner C,Buhl R,Mehdorn HM

更新日期：2009-06-01 00:00:00

abstract：:Parkinson's disease (PD) the second most common age-associated progressive neurodegenerative disorder is characterized by loss of dopaminergic neurons, cytoplasmic inclusions of aggregated proteins (Lewy bodies), and neuroinflammation. The inflammation of neurons causes release of various inflammatory mediators (IFNs,...

journal_title：Neurological research

authors： Pal R,Tiwari PC,Nath R,Pant KK

更新日期：2016-12-01 00:00:00

abstract：:Excessive calcium influx has been implicated in the pathophysiology of ischemic cerebral damage. The effects of nimodipine, a calcium antagonist, on the Na(+)-K+/MG+2 ATPase activity, Ca+2/Mg+2 ATPase, lipid peroxidation, and early ultrastructural findings were examined at the acute stage of ischemia in the rat brain....

journal_title：Neurological research

authors： Ildan F,Göçer AI,Tuna M,Polat S,Kaya M,Isbir T,Cetinalp E

更新日期：2001-01-01 00:00:00

abstract：:Phosphorus magnetic resonance spectroscopy (31P-MRS) was made to measure changes in brain high energy phosphate compounds, adenosine triphosphate (ATP) and phosphocreatine (PCr), inorganic phosphorus (Pi) and intracellular pH (pHi) during a prolonged period of incomplete brain ischaemia produced, in anaesthetized dogs...

journal_title：Neurological research

authors： Anderson ML,Smith DS,Nioka S,Subramanian H,Garcia JH,Halsey JH,Chance B

更新日期：1990-12-01 00:00:00

abstract：:Brain tumours were induced by intracerebral inoculation of beagle puppies with Avian sarcoma virus (ASV) suspension. The inoculation produced solitary or multiple sarcomas in three dogs and intraventricular anaplastic gliomas in four dogs. At the time of the first tumour positive CT-control Iodine-125 seeds (activity ...

journal_title：Neurological research

authors： Ostertag CB,Warnke P,Kleihues P,Bigner DD

更新日期：1984-12-01 00:00:00

abstract：OBJECTIVE:We sought to assess the current status of blood pressure control and the use of antihypertensive drugs in patients with ischemic stroke (IS) or transient ischemic attack (TIA) in China. SUBJECTS AND METHODS:A cross-sectional study (across 19 urban outpatient clinics) on secondary stroke prevention measures w...

journal_title：Neurological research

authors： Wang Y,Wu D,Zhou Y,Zhao X,Wang C,Liu L,Liao X,Wang Y

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVES:To find new biomarkers by stimulating acupuncture point GB34 (Yangneungcheon) which has neuroprotective effect on the mouse model of Parkinson's disease, analysis of cDNA microarray on mRNAs of the substantia nigra was performed. METHODS:Male C57BL/6 mice were divided into two groups: 1-methyl-4-phenyl-1,2,...

journal_title：Neurological research

authors： Hong MS,Park HK,Yang JS,Park HJ,Kim ST,Kim SN,Park JY,Song JY,Park HK,Jo DJ,Park SW,HwanYun D,Ban JY,Chung JH

更新日期：2010-02-01 00:00:00

abstract：:To investigate the migration of neural stem cells as well as neural plastic changes in epileptic brain, spaciotemporal expression of immunoreactive highly polysialylated neural cell adhesion molecule (PSA-NCAM) was examined in amygdala kindling development of rat. The neural migration and synaptic remodeling detected ...

journal_title：Neurological research

authors： Sato K,Iwai M,Nagano I,Shoji M,Abe K

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To evaluate by MR diffusion weighted image (DWI-MR) the presence of new ischemic cerebral lesions after carotid artery stenting (CAS) and distal cerebral protection, in patients with internal carotid artery (ICA) stenosis >70. METHODS:Sixty-seven CAS were performed under cerebral protection with a distal fil...

journal_title：Neurological research

authors： González A,Piñero P,Martínez E,González-Marcos JR,Rafel E,Mayol A,Gil-Peralta A

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Giant and large intracranial aneurysms represent enormous therapeutic challenges for neurosurgeons as well as for endovascular therapists. Since they may involve entire vessels or be irregular in shape, the rate of complete obliteration with GDCs is low and the incidence of recanalization is very high. So th...

journal_title：Neurological research

authors： Yang X,Wu Z,Mu S,Li Y,Lv M

更新日期：2008-07-01 00:00:00

abstract：:Two hundred and sixty-one neurologically asymptomatic patients were examined by computed tomography (CT) following a variable number of transient ischaemic attacks (TIAs) experienced over different time intervals. Cerebral infarcts were discovered in 101 patients. Dominant hemisphere infarcts were usually small, of re...

journal_title：Neurological research

authors： Turnbull IW,Bannister CM

更新日期：1985-12-01 00:00:00

abstract：OBJECTIVE:Elevated homocysteine level is a risk factor for ischemic stroke and associated with small vessel disease such as confluent leukoaraiosis in white and black population. We investigated the relationship between the total serum homocysteine level and ischemic stroke subtypes in Chinese population. METHODS:Thre...

journal_title：Neurological research

authors： Ma Y,Zhao X,Zhang W,Liu L,Wang Y,Fang R,Wang Y

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Hypothermia has shown promise as a neuroprotective strategy for stroke. The use of whole body hypothermia has limited clinical utility due to many severe side effects. Selective brain cooling, or local brain hypothermia, has been previously proposed as an alternative treatment strategy. This st...

journal_title：Neurological research

authors： Wang B,Wu D,Dornbos Iii D,Shi J,Ma Y,Zhang M,Liu Y,Chen J,Ding Y,Luo Y,Ji X

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVES:Intracranial aneurysms (IAs) of the posterior circulation (PC) rupture more frequently and their morbidity and mortality rates are higher compared to anterior circulation. Morphological parameters such as size ratio (SR), inflow angle and parent artery geometry are believed to contribute significantly in det...

journal_title：Neurological research

authors： Tykocki T,Nauman P,Dow Enko A

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:Vascular endothelial growth factor is a potent stimulator of angiogenesis; activation of hypoxia inducible factor-1alpha and p44/42 mitogen-activated protein kinase pathways has been associated with vascular endothelial growth factor production. The present study examined if thrombin modulates vascular endoth...

journal_title：Neurological research

authors： Xu Y,Gu Y,Keep RF,Heth J,Muraszko KM,Xi G,Hua Y

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVES:In the clinical set, autologus nerve grafts are the current option for reconstruction of nerve tissue losses. The length of the nerve graft has been suggested to affect outcomes. Experiments were performed in the rat in order to test this assumption and to detect a possible mechanism to explain differences i...

journal_title：Neurological research

authors： Bertelli JA,Taleb M,Mira JC,Ghizoni MF

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:High blood pressure (BP) is a major risk factor for stroke and all of its pathological subtypes including subarachnoid hemorrhage (SAH). However, there is little evidence demonstrating whether failure to have regular BP measured could result in underestimation of people at risk for SAH. Therefore, we aimed ...

journal_title：Neurological research

authors： Shiue I,Hankey GJ,Arima H,Anderson CS

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVES:Natalizumab is a drug with documented efficacy in relapsing-remitting multiple sclerosis (RRMS). The mechanism of action of natalizumab has immunosuppressive properties and it is not yet investigated if treatment with natalizumab affects the immunological response to vaccination. This study aims to investig...

journal_title：Neurological research

authors： Vågberg M,Kumlin U,Svenningsson A

更新日期：2012-09-01 00:00:00

abstract：:Acute blood-brain barrier (BBB) opening in cerebral ischemia is an often observed but seldom studied phenomenon. Increased permeability has been implicated with several consequences including exacerbating ischemic injury, leading to hemorrhagic transformation (HT) and also predictive of chronic damage and a way of del...

journal_title：Neurological research

authors： Nagaraja TN,Keenan KA,Brown SL,Fenstermacher JD,Knight RA

更新日期：2007-01-01 00:00:00