Abstract：
OBJECTIVES:To evaluate the effect of vitamin A supplementation 24 h after delivery on breastmilk retinol concentration. METHODS:Fifty low income women were randomly assigned to a single oral dose of 209 micromol of Vitamin A or none at delivery. Maternal serum and breastmilk retinol levels and infant morbidity and anthropometry were serially assessed. RESULTS:Mean (95% CI) serum retinol levels increased in the supplemented mothers at 2.77 (2.3, 3.2) compared to 1.15 (0.9, 1.4) micromol/l in controls (P < 0.05) and remained at a significantly higher level of 1.59 (1.4, 1.8) micromol/l compared to 1.33 (1.8, 1.5) micromol/l in the control group (P < 0.001) up to a period of three months. Breastmilk retinol concentration was also greater at 24 h after supplementation, mean (CI) 11.34 (9.0, 13.7) micromol/l, compared to 2.95 (2.3, 3.6) micromol/l in the control group (P < 0.0001), and remained higher for the next six months at 1.06 (0.9, , 1.3) micromol/l compared to 0.73 (0.6, 0.8) micromol/l in the control group (P < 0.02). Infants of the supplemented mothers had reduced mean duration of respiratory tract infection of 3.1 (2.7, 3.5) days compared to 3.7 (3.3, 4.2) days (P < 0.03) and mean incidence of febrile illness 0.1 (0.1, 0.1) compared to control infants 0.3 (0.3, 0.3) days, (P < 0.002). CONCLUSION:Vitamin A supplementation of malnourished mothers maintains higher breastmilk retinol concentration for at least six months and reduces the duration of respiratory tract infection and febrile illness in their breastfed infants.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Roy SK,Islam A,Molla A,Akramuzzaman SM,Jahan F,Fuchs Gdoi
10.1038/sj.ejcn.1600398subject
Has Abstractpub_date
1997-05-01 00:00:00pages
302-7issue
5eissn
0954-3007issn
1476-5640journal_volume
51pub_type
临床试验,杂志文章,随机对照试验abstract：BACKGROUND:Changes in lifestyle and increases in sedentary activities during recent decades have been shown to contribute to the prevalence of overweight in adolescents. OBJECTIVES:To determine the inter-individual variability and the day-to-day variations in daily energy expenditure (DEE) and activity pattern, and th...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601395
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abstract：OBJECTIVE:To investigate the possible differential role of refined and whole grain cereals on the risk of upper digestive and respiratory tract neoplasms. DESIGN:Hospital-based case-control study. SETTING:University Hospital of Lausanne, Switzerland. SUBJECTS:A total of 156 incident cases of cancers of the oral cavi...
journal_title：European journal of clinical nutrition
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doi：10.1038/sj.ejcn.1601043
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abstract：:The effect on total serum cholesterol and its lipoprotein fractions of supplementation of the diet with amla (Emblica officinalis, Gaertn., the Indian gooseberry) was studied in normal and hypercholesterolaemic men aged 35-55 years. The supplement was given for a period of 28 d in the raw form. Both normal and hyperch...
journal_title：European journal of clinical nutrition
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更新日期：1988-11-01 00:00:00
abstract：OBJECTIVE:To evaluate the in vivo effects of moderate consumption of red wine, beer and spirits on antioxidants, antioxidant enzymes and antioxidant capacity. DESIGN:Randomized, diet-controlled, cross-over study. SUBJECTS:Twelve apparently healthy, non-smoking middle-aged men were included; 11 of them completed the s...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1038/sj.ejcn.1601061
更新日期：2000-07-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:The cardiovascular benefit of increasing fruit and vegetable (F&V) intake following diagnosis of diabetes remains unknown. We aimed to describe how quantity and variety of F&V intake, and plasma vitamin C, change after diagnosis of type 2 diabetes and examine whether these changes are associated w...
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journal_title：European journal of clinical nutrition
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doi：10.1038/sj.ejcn.1602567
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abstract：BACKGROUND/OBJECTIVES:This study evaluates the feasibility among preschoolers of the 2 × 24-h dietary recalls (24-HDRs) method combined with a food-recording booklet (FRB), using EPIC-Soft pc-program for the 24-HDR (the software developed to conduct 24-HDRs in the European Prospective Investigation into Cancer and Nutr...
journal_title：European journal of clinical nutrition
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abstract：BACKGROUND/OBJECTIVES:Long-term observational cohorts provide the opportunity to investigate the potential impact of dietary patterns on death. We aimed to investigate all-cause death according to the consumption of selected food groups, and then to identify those independently associated with reduced mortality. SUBJE...
journal_title：European journal of clinical nutrition
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更新日期：2016-06-01 00:00:00
abstract：BACKGROUND:Mediterranean diets are felt to be healthful diets linked with reduced mortality from diet-related noncommunicable diseases. OBJECTIVE:To examine trends in diet, activity, obesity and diet-related noncommunicable diseases for Spain and compare these with other European countries, particularly those from the...
journal_title：European journal of clinical nutrition
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更新日期：2002-10-01 00:00:00
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更新日期：2018-04-01 00:00:00
abstract：:The principal metabolic function of vitamin B6 is in amino acid metabolism, although the greater part of the body's vitamin B6 is in muscle, associated with glycogen phosphorylase, and the vitamin also has an important role in the actions of steroid hormones. It is usual to calculate vitamin B6 requirements relative t...
journal_title：European journal of clinical nutrition
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更新日期：1989-05-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Dysphagia is relatively common in patients with Parkinson disease (PD) and can have a negative impact on their quality of life; therefore, it is imperative that its prevalence in PD patients is studied. The aim of this study was to explore the prevalence and clinical correlation of dysphagia in Ch...
journal_title：European journal of clinical nutrition
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更新日期：2018-01-01 00:00:00
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journal_title：European journal of clinical nutrition
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更新日期：2009-11-01 00:00:00
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journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：2002-07-01 00:00:00
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journal_title：European journal of clinical nutrition
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更新日期：2014-01-01 00:00:00
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journal_title：European journal of clinical nutrition
pub_type： 杂志文章
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更新日期：2019-11-01 00:00:00
abstract：:This article was originally published under Nature Research's License to Publish, but has now been made available under a CC BY 4.0 license. The PDF and HTML versions of the article have been modified accordingly. ...
journal_title：European journal of clinical nutrition
pub_type： 已发布勘误
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journal_title：European journal of clinical nutrition
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journal_title：European journal of clinical nutrition
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journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
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journal_title：European journal of clinical nutrition
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journal_title：European journal of clinical nutrition
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更新日期：1998-08-01 00:00:00
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journal_title：European journal of clinical nutrition
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journal_title：European journal of clinical nutrition
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journal_title：European journal of clinical nutrition
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更新日期：2010-11-01 00:00:00
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journal_title：European journal of clinical nutrition
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更新日期：1998-09-01 00:00:00
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journal_title：European journal of clinical nutrition
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更新日期：2011-05-01 00:00:00
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journal_title：European journal of clinical nutrition
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更新日期：2000-07-01 00:00:00
abstract：:Dehydration is a reliable predictor of impaired cognitive status. Objective data, using tests of cortical function, support the deterioration of mental performance in mildly dehydrated younger adults. Dehydration frequently results in delirium as a manifestation of cognitive dysfunction. Although, the occurrence of de...
journal_title：European journal of clinical nutrition
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