Abstract：
OBJECTIVE:To investigate the possible differential role of refined and whole grain cereals on the risk of upper digestive and respiratory tract neoplasms. DESIGN:Hospital-based case-control study. SETTING:University Hospital of Lausanne, Switzerland. SUBJECTS:A total of 156 incident cases of cancers of the oral cavity and pharynx, 101 of the oesophagus, 40 of the larynx, and 349 control subjects admitted for a wide spectrum of acute non-neoplastic conditions. INTERVENTION:Trained interviewers collected information using a structured and validated questionnaire. Odds ratios (OR) of various cancers for a tertile increment of intake of refined and whole grains were estimated using unconditional multiple logistic regression. RESULTS:Refined grains were directly related to the risk of cancer of the oral cavity and pharynx (OR=1.9 for the highest tertile), oesophagus (OR=3.7) and larynx (OR=4.0). In contrast, whole grain cereals were protective, with OR of 0.6 for oral cavity and pharynx, 0.3 for oesophagus, and 0.7 for larynx. For the three sites combined, the OR for the highest tertile was 5.7 for refined grains and 0.5 for wholegrains. The trends in risk for refined grains were significant for all sites and their combination, and for wholegrain for oesophageal cancer and all sites. CONCLUSIONS:Even if inference on causality and the biological interpretation remain open to discussion, the present data indicate and further quantify that refined cereals are an unfavourable, but whole grain ones a favourable indicator of the risk of upper aerodigestive and respiratory tract neoplasms.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Levi F,Pasche C,Lucchini F,Chatenoud L,Jacobs DR Jr,La Vecchia Cdoi
10.1038/sj.ejcn.1601043subject
Has Abstractpub_date
2000-06-01 00:00:00pages
487-9issue
6eissn
0954-3007issn
1476-5640journal_volume
54pub_type
杂志文章abstract：OBJECTIVE:The aim of this study was to assess the effects of fish oil supplementation in pregnancy on maternal erythrocyte fatty acid composition at different stages of pregnancy and in the post-partum period, and on neonatal erythrocyte fatty acid composition. DESIGN:A double-blind, randomised, placebo-controlled stu...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1038/sj.ejcn.1601825
更新日期：2004-03-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:There is a lack of detailed data on fish consumption in European children and adolescents. We therefore investigated fish consumption patterns, portion sizes and estimated intakes of long-chain n-3 polyunsaturated fatty acids (PUFA; eicosapentaenoic acid, docosahexaenoic acid). SUBJECTS/METHODS:F...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2009.40
更新日期：2009-09-01 00:00:00
abstract：OBJECTIVES:To evaluate body fatness in subjects complying with common public health guidelines for lipid and alcohol intake as well as physical activity participation. SUBJECTS:A sample of 358 male subjects who participated in phase 1 of the Quebec Family Study. DESIGN:The association between adiposity, lipid and alc...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1995-11-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Depression can decrease quality of life and affect health outcomes in older population. We investigated whether different intake levels of folate, vitamin B6 and B12 were associated with a 3-year depression incidence among generally healthy, community-dwelling older men and women. SUBJECTS/METHOD...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2015.202
更新日期：2016-03-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:To compare body fat mass at the same stage of pubertal maturation, genital stage 2 (G2), in a Spanish and in a Mexican sample of boys. SUBJECTS/METHODS:Data from Spain (n=177) were from a previous longitudinal clinical follow-up and data from Mexico (n=91) from a cross-sectional study. Subjects w...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2008.37
更新日期：2009-06-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:The European Food Safety Authority approved a health claim (ID558) relating to lowered postprandial glycaemia when fructose replaces 30% of sucrose in foods and beverages. We assessed the effects of partial replacement of sucrose with fructose on serum glucose, uric acid and blood pressure. SUBJE...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1038/s41430-018-0134-x
更新日期：2018-12-01 00:00:00
abstract：:We previously detected that ~50% of kidney transplant patients (KTPs) present sarcopenia using the first European Working Group on Sarcopenia in Older People (EWGSOP1) consensus. Our aim was to evaluate the agreement between the sarcopenia diagnosis using EWGSOP1 and the new consensus (EWGSOP2) in KTPs. A cross-sectio...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/s41430-019-0535-5
更新日期：2020-07-01 00:00:00
abstract：OBJECTIVES:Human colostrum is known to be important for the protection of infants against infection by pathogenic microorganisms. This protection is thought to be due, partially, to various neutral and acidic oligosaccharides that are present in colostrum and milk. However, the concentrations of each of the oligosaccha...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1602738
更新日期：2008-04-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:There is little objective information regarding nutrition transition in African countries. We assessed trends in nutrition patterns in the Seychelles between 1989 and 2011. SUBJECTS/METHODS:Population-based samples were obtained in 1989, 1994 and 2011 and participants aged 25-44 are considered in...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2012.199
更新日期：2013-02-01 00:00:00
abstract：OBJECTIVE:In term infants the relationship between visual acuity and dietary fatty acid composition is not consistent, possibly due to confounders, which were mostly neglected in the studies concerned. In the current study, therefore, the influence of the essential fatty acid status and potential confounders on the vis...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1600868
更新日期：1999-11-01 00:00:00
abstract：:Over the past three decades, undernutrition in Thailand has drastically reduced by over seven times. However, since 1995 the number of patients afflicted with non-communicable diseases, such as diabetes mellitus, has rapidly increased, even among the young. Unhealthy life styles due to urbanization are a major reason ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,评审
doi：10.1038/ejcn.2017.52
更新日期：2017-07-01 00:00:00
abstract：:Recent recognition of the early onset and high prevalence of wasting (30%) and stunting (20%) among infants 0-5 months in India draws attention to the need to understand the causes and develop prevention strategies. Such growth failure has dire consequences in the short (increased mortality) and long-term (loss of hum...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,评审
doi：10.1038/ejcn.2013.18
更新日期：2013-05-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:It is well established that combining a reduced calorie, low-fat diet with the lipase inhibitor orlistat results in significantly greater weight loss than placebo plus diet. This weight loss is accompanied by changes in adipose tissue (AT) distribution. As 60 mg orlistat is now available as an ove...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章
doi：10.1038/ejcn.2011.108
更新日期：2011-11-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Cross-sectionally, educational attainment is strongly associated with the prevalence of obesity, but this association is less clear for weight change during adult life. The objective of this study is to examine the association between educational attainment and weight change during adult life in t...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2012.55
更新日期：2012-08-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:To conduct an analysis of associations between eating behaviours and weight status in 2-year-old children. SUBJECTS/METHODS:Data were collected prospectively in the maternal-infant dyad Cork BASELINE Birth Cohort Study. The weight status of children aged 2 years (n=1189) was assigned using the In...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2015.130
更新日期：2015-12-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Children born to human immunodeficiency virus (HIV)-infected women are susceptible to undernutrition, but modifiable risk factors and the time course of the development of undernutrition have not been well characterized. The objective of this study was to identify maternal, socioeconomic and child...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1038/ejcn.2012.136
更新日期：2012-11-01 00:00:00
abstract：:Obesity is a multifactorial and complex affectation that is characterized by a long-term excess energy intake (EI) above energy expenditure (EE). Since fat oxidation seems to be dependent on SNS activation and also seems to remain acutely unaffected by fat intake, this macronutrient is certainly partly responsible for...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,评审
doi：10.1038/sj.ejcn.1600497
更新日期：1997-12-01 00:00:00
abstract：BACKGROUND:Older people are becoming an increasingly important proportion of the populations of developing countries, yet little information exists on their nutritional status or social conditions. OBJECTIVE:To assess the nutritional status of older people in rural Malawi. DESIGN:Cross-sectional study. SETTING:Lilon...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1600617
更新日期：1998-09-01 00:00:00
abstract：BACKGROUND:The relationship between hydrogen and methane production is a possible confounding factor in the interpretation of H(2) breath tests (HBT), but is usually disregarded for the interpretation of HBT and, in most instances, only H(2) excretion is measured. The present study was designed to evaluate the effect o...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601651
更新日期：2003-09-01 00:00:00
abstract：:Adult (primary) lactose malabsorption is practically universal in Africans of Bantu and San ('Bushmen') stock. Recent environmental changes, especially in rural areas, have exacerbated rates of malnutrition in hospital patients belonging to these groups. In order to assess the advisability of using milk as a nutrition...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1990-07-01 00:00:00
abstract：OBJECTIVE:Research on the impact of maternal physical activity on pregnancy outcomes has often employed subjective measures of physical activity obtained by diary or questionnaire. This study investigates the feasibility of using accelerometry as an objective measure of physical activity of pregnant women compared with...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1602329
更新日期：2006-03-01 00:00:00
abstract：:The growth literature from developing countries is reviewed to assess the extent to which stunting, a phenomenon of early childhood, can be reversed in later childhood and adolescence. The potential for catch-up growth increases as maturation is delayed and the growth period is prolonged. However, maturational delays ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,评审
doi：
更新日期：1994-02-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:The evidence regarding fatty acids and breast cancer risk is inconclusive. Adipose tissue fatty acids can be used as biomarkers of fatty acid intake and of endogenous fatty acid exposure. Fatty acids in adipose tissue are correlated owing to common dietary sources and shared metabolic pathways, wh...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2014.28
更新日期：2014-10-01 00:00:00
abstract：OBJECTIVE:To investigate the association between dietary patterns and risk of a first nonfatal acute myocardial infarction (MI) in Costa Rican adults. DESIGN:Population-based case-control study. SUBJECTS:A total of 496 incident MI cases and 518 population-based randomly selected controls matched to the cases by age (...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1602381
更新日期：2006-06-01 00:00:00
abstract：:Food composition tables were studied from nine European countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC): Denmark, France, Germany, Greece, Great Britain, Italy, The Netherlands, Spain and Sweden. They were compared from the point view of availability, definition, anal...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1600677
更新日期：1999-01-01 00:00:00
abstract：OBJECTIVE:The aim was to examine the concordance of diet with the recommended cholesterol lowering diet in Coronary Heart Disease (CHD) patients receiving usual care. DESIGN:CHD patients were selected for a survey from hospital records at least six months after hospitalization. Four patient groups divided according to...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1600549
更新日期：1998-04-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Exposure to polycyclic aromatic hydrocarbons (PAHs) during pregnancy is known to increase oxidative stress, which may influence pregnancy outcomes and health of the child. SUBJECTS/METHODS:This study investigated whether fruit and vegetable intake modifies the relationship between exposure to PAH...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2011.77
更新日期：2011-10-01 00:00:00
abstract：OBJECTIVES:To assess the influence of a low-fat, low-energy diet on the intake of vitamins and minerals in patients with overweight and hyperlipidemia. SETTING:Outpatient clinic for hyperlipidemia treatment. SUBJECTS:A total of 134 subjects chosen from patients attending Outpatient Clinic of Metabolic Diseases. INTE...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601467
更新日期：2002-12-01 00:00:00
abstract：OBJECTIVE:To determine the origin of the poor digestibility of banana starch granules in the human small intestine. DESIGN:The subjects received the same experimental meal. SETTING:Nutrition Research Unit, Laënnec Hospital, CHU, Nantes. SUBJECTS:Six healthy young subjects. INTERVENTIONS:The digestion of raw green b...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1995-02-01 00:00:00
abstract：OBJECTIVE:To assess the relationship of energy stress during pregnancy and lactation to maternal body stores in marginally nourished rural Bangladeshi women. SUBJECTS AND METHODS:Two-hundred and fifty-two women were followed from 5-7 months of pregnancy until 6 months postpartum. Energy intake was estimated during pre...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601514
更新日期：2003-01-01 00:00:00
