Abstract：
:The principal metabolic function of vitamin B6 is in amino acid metabolism, although the greater part of the body's vitamin B6 is in muscle, associated with glycogen phosphorylase, and the vitamin also has an important role in the actions of steroid hormones. It is usual to calculate vitamin B6 requirements relative to protein intake. An adequate intake to meet the requirements of virtually the whole population is generally considered to be 15 micrograms/g dietary protein. This is the basis of RDAs in most countries, although differences of interpretation and application of the experimental data result in widely differing recommendations from different authorities. Current RDAs range between 1.5 and 2.2 mg/d. A minimum safe intake, below which an individual would have a high probability of deficiency, is 11 micrograms/g dietary protein. Higher intakes are required in pregnancy and lactation (although there are problems in determining the requirement of the infant), and possibly also in the elderly. Average intakes of vitamin B6 in developed countries meet the target of 15 micrograms/g dietary protein, although there is biochemical evidence of inadequate vitamin B6 nutritional status in 10-25 per cent of the population. It is not know whether this has any clinical significance; it is unlikely that normal patterns of food intake would permit a significantly greater average intake of the vitamins without fortification or the use of supplements. There is little evidence that pharmacological doses of vitamin B6 have any beneficial effect. Neurological damage has been reported at extremely high intakes (in excess of 500 mg/d), and even more modest doses (50-100 mg/d) cannot be regarded as being without hazard.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Bender DAsubject
Has Abstractpub_date
1989-05-01 00:00:00pages
289-309issue
5eissn
0954-3007issn
1476-5640journal_volume
43pub_type
杂志文章,评审abstract：:Effects of dietary intervention on dietary habits and nutrient levels were studied in 240 women aged 50-65 years who had been operated for a stage I-II breast cancer. Following surgery the women who had participated in a dietary history interview were randomly assigned to one of two groups. The intervention group (n =...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1990-09-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:To facilitate the development of practical public health advice targeted at childhood obesity (OB) prevention and make the intervention programs more effective, one has to promote the most protective habits and limit or modify the risk factors. The objective of the present study was to recognize t...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2014.89
更新日期：2014-10-01 00:00:00
abstract：OBJECTIVE:To assess whether consumption of 100 ml of whisky or red wine by healthy male subjects increased plasma total phenol content and antioxidant capacity. DESIGN:A Latin square arrangement to eliminate ordering effects whereby, after an overnight fast, nine volunteers consumed 100 ml of red wine, malt whisky or ...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章
doi：10.1038/sj.ejcn.1600635
更新日期：1998-10-01 00:00:00
abstract：BACKGROUND:There is a need for objective and universally applicable biomarkers for the intake of foods believed to affect human health. OBJECTIVE:The purpose of this feeding study was to test whether plasma concentrations of carotenoids could be used to distinguish recommended consumption of mixed fruits and vegetable...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1038/sj.ejcn.1601945
更新日期：2004-08-01 00:00:00
abstract：OBJECTIVE:To ascertain whether body mass index (BMI) cutoffs calculated according to age and pubertal stage are superior to BMI cutoffs calculated on the basis of age alone at correctly identifying children and adolescents with high levels of adiposity. DESIGN:Cross-sectional study. SETTING:Dunedin, a university city...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601608
更新日期：2003-06-01 00:00:00
abstract：OBJECTIVE:To assess the effects in humans of regular ingestion of black tea on haemostasis-related variables and cell adhesion molecules. DESIGN:Twenty-two subjects were recruited from the general population to a randomised-controlled crossover study. Subjects stopped drinking tea, apart from that provided, for the du...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1038/sj.ejcn.1601231
更新日期：2001-10-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Hypoglycemic effect of camel milk supplementation in experimental rat model and significant reduction in doses of insulin in type 1 diabetic patients have been observed in our previous studies. This long-term study was undertaken to assess the efficacy, safety and acceptability of camel milk as an...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1038/ejcn.2011.98
更新日期：2011-09-01 00:00:00
abstract：:Comparison of percent fat mass across different body composition analysis devices is important given variation in technology accuracy and precision, as well as the growing need for cross-validation of devices often applied across longitudinal studies. We compared EchoMRI-AH and Lunar iDXA quantification of percent bod...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2016.236
更新日期：2017-04-01 00:00:00
abstract：OBJECTIVES:Study 1: To establish the validity of scores on Nutrition Screening Tool for Every Preschooler (NutriSTEP), a community-based parent-administered screening tool for assessing nutrition risk, by comparing scores to an expert rating. Study 2: To demonstrate test-retest reliability of NutriSTEP. SUBJECTS/METHO...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1602780
更新日期：2008-06-01 00:00:00
abstract：:Insulin resistance is common and is determined by physiological (aging, physical fitness), pathological (obesity) and genetic factors. The metabolic compensatory response to insulin resistance is hyperinsulinaemia, the primary purpose of which is to maintain normal glucose tolerance. The 'carnivore connection' postula...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,评审
doi：10.1038/sj.ejcn.1601351
更新日期：2002-03-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:There is limited published research examining lipid-soluble vitamins in human immunodeficiency virus (HIV)-infected pregnant women, particularly in resource-limited settings. SUBJECTS/METHODS:This is an observational analysis of 1078 HIV-infected pregnant women enrolled in a trial of vitamin supp...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1038/ejcn.2010.76
更新日期：2010-08-01 00:00:00
abstract：OBJECTIVE:Total body water can be calculated using stable isotopes by two alternative approaches known as the plateau method and the back extrapolation method. These methods treat the isotopic data in different ways and consequently do not necessarily produce identical values for total body water. Total body water was ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1994-07-01 00:00:00
abstract：:A World Health Organization (WHO) Expert Consultation on Waist Circumference (WC) and Waist-Hip Ratio (WHR) was convened in Geneva from 8 to 11 December 2008 to consider approaches to developing international guidelines for indices and action levels in order to characterize health risks associated with these measures ...
journal_title：European journal of clinical nutrition
pub_type：
doi：10.1038/ejcn.2009.139
更新日期：2010-01-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:The purpose of this work was to investigate the association between coffee drinking and diabetes development and potential mediation by oxidative stress and inflammatory biomarkers. SUBJECTS/METHODS:In 2001-2002, a random sample of 1514 men (18-87 years old) and 1528 women (18-89 years old) were ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2015.98
更新日期：2015-11-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Little is known about whether waist circumference (WC) has increased disproportionately relative to body mass index (BMI) around the world. SUBJECTS/METHODS:Data came from the US National Health and Nutrition Examination Survey (1988-1994 and 2007-2010), Health Survey for England (1992-1993 and 2...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2015.71
更新日期：2015-12-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:The use of simple screening tools to measure nutritional adequacy in a public health context in developed countries are currently lacking. We explore the relationship between food variety and nutrient intake of London school children using a simple tool with potential use for screening for inadequ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/s41430-017-0070-1
更新日期：2018-11-01 00:00:00
abstract：OBJECTIVE:To collect (i) baseline data and (ii) execute a large multicentre study examining the effect of trans alpha-linolenic acid on its incorporation into plasma lipids and on risk factors for coronary heart disease. DESIGN:Male volunteers were recruited and the habitual diet assessed by a 4-d weighed record. Fatt...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1038/sj.ejcn.1600903
更新日期：2000-02-01 00:00:00
abstract：:This paper evaluates the safety for humans with regard to consumption of protein hydrolysates and fractions thereof, including bioactive peptides. The available literature on the safety of protein, protein hydrolysates, fractions thereof and free amino acids on relevant food legislation is reviewed and evaluated. A ne...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,评审
doi：10.1038/ejcn.2009.56
更新日期：2009-10-01 00:00:00
abstract：OBJECTIVES:To estimate the energy cost of resting (RMR), sitting and standing for urban Indian adults and compare these estimates with the reported values. DESIGN:Energy costs were measured using oxylog while body fat was estimated using equipment (HBF300, OMRON Corporation, Japan) that works on the principle of bioel...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601211
更新日期：2001-08-01 00:00:00
abstract：OBJECTIVE:Twins in developing countries may be disadvantaged due to their small size at birth, compromised nutrition and high infection risk. Although twinning is common in Africa, there are few longitudinal studies of growth and morbidity in this high-risk group. The aim of the present paper was to describe growth and...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1602356
更新日期：2006-05-01 00:00:00
abstract：OBJECTIVE:To assess four-year changes in different measures of health, functional limitations and activities of daily living occurring in elderly Europeans who participated in the SENECA surveys of 1988/89 and 1993. METHODS:Similar questions on self-perceived health, chronic diseases, drug intake and activities of dai...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1996-07-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Previous research has shown, in predominantly European populations, that dietary patterns are evident early in life. However, little is known about early-life dietary patterns in Australian children. We aimed to describe dietary patterns of Australian toddlers and their associations with socio-dem...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1038/ejcn.2013.23
更新日期：2013-06-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Cold exposure increases thermogenesis and could improve insulin sensitivity. We hypothesized a blunted response in the metabolic syndrome (MetS). SUBJECTS/METHODS:Twenty older adults 59 ± 10.4 years (with MetS, MetS+, n = 9; without MetS, MetS-, n = 11) completed a randomized crossover design of ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1038/s41430-017-0058-x
更新日期：2018-10-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Obese infants are more susceptible to develop adulthood obesity and its related comorbidities. Previous studies have shown the presence of hormones and growth factors in maternal breast milk that may influence infant adiposity. The aim of this study was to investigate differences in concentrations...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2014.205
更新日期：2015-05-01 00:00:00
abstract：OBJECTIVE:To determine whether dual-energy X-ray absorptiometry (DXA) is a valid method for body composition assessment of obese and non-obese subjects. DESIGN:Cross-sectional study. SUBJECTS:Chinese women living in Hong Kong; 66 of 91 subjects had body mass index (BMI) of >25 kg/m2. MEASUREMENTS:Anthropometrics, in...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1600875
更新日期：1999-12-01 00:00:00
abstract：BACKGROUND:Current lifestyles and the choice and availability of foods may influence the eating patterns of children. The aim of this study was to investigate the meal and snacking patterns of school-aged children in Scotland. METHODS:A sub-sample of 156 children (5-17 years) from the national Survey of Sugar Intake a...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2009.87
更新日期：2009-11-01 00:00:00
abstract：BACKGROUND/OBJECTIVE:To study whether a free supply of vitamin D(2) drops to 6-week-old infants together with tailor-made information handouts improves the vitamin D status after 7 weeks in the intervention group compared to a control group. SUBJECTS/METHODS:In this cluster randomized controlled trial in eight child h...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1038/sj.ejcn.1602982
更新日期：2009-04-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:In international surveys of food consumption and nutrient intake, it is essential that the dietary data are comparable when different databases and calculation programs are used. The aim of the present analysis was to examine the comparability of nutrient intake data calculated on the basis of ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601639
更新日期：2003-09-01 00:00:00
abstract：OBJECTIVES:To examine the effects of physical activity (PA) in adults with or without prehypertension at baseline on systolic blood pressure (SBP), diastolic blood pressure (DBP), and hypertension risk by gender. METHODS:A total of 5986 men and 6525 women (≥18 years old) without hypertension-related disease at baselin...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/s41430-020-0653-0
更新日期：2020-05-13 00:00:00
abstract：OBJECTIVE:The aims of this study were to validate BOD POD in a wide sample of healthy and independent Mexican elderly men and women subjects using the 4 compartment (4C) model as the reference method, and to evaluate the assumptions of the densitometric two-compartment (2C) model. DESIGN:Cross-sectional study designed...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1602597
更新日期：2007-07-01 00:00:00
