Trans fatty acids, insulin resistance and diabetes.

Abstract:

:The possible relationship between consumption of trans fatty acids (TFAs) and risk of insulin resistance or development of diabetes mellitus type II has been considered by a number of human and animal studies over the past decade. This review evaluates the evidence, and concludes that there is limited evidence for a weak association at high TFA intakes, but very little convincing evidence that habitual exposure as part of a standard western diet has a significant contribution to risk of diabetes or insulin resistance. The possibility of increased risk for individuals with particular genotypes (such as the FABP2 Thr54 allele) is of interest, but further work would be required to provide sufficient evidence of any association.

journal_name

Eur J Clin Nutr

authors

Thompson AK,Minihane AM,Williams CM

doi

10.1038/ejcn.2010.240

subject

Has Abstract

pub_date

2011-05-01 00:00:00

pages

553-64

issue

5

eissn

0954-3007

issn

1476-5640

pii

ejcn2010240

journal_volume

65

pub_type

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