Abstract：
:While putative feedback signals arising from adipose tissue are commonly assumed to provide the molecular links between the body's long-term energy requirements and energy intake, the available evidence suggests that the lean body or fat-free mass (FFM) also plays a role in the drive to eat. A distinction must, however, be made between a 'passive' role of FFM in driving energy intake, which is likely to be mediated by 'energy-sensing' mechanisms that translate FFM-induced energy requirements to energy intake, and a more 'active' role of FFM in the drive to eat through feedback signaling between FFM deficit and energy intake. Consequently, a loss of FFM that results from dieting or sedentarity should be viewed as a risk factor for weight regain and increased fatness not only because of the impact of the FFM deficit in lowering the maintenance energy requirement but also because of the body's attempt to restore FFM by overeating-a phenomenon referred to as 'collateral fattening'. A better understanding of these passive and active roles of FFM in the control of energy intake will necessitate the elucidation of peripheral signals and energy-sensing mechanisms that drive hunger and appetite, with implications for both obesity prevention and its management.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Dulloo AG,Jacquet J,Miles-Chan JL,Schutz Ydoi
10.1038/ejcn.2016.256subject
Has Abstractpub_date
2017-03-01 00:00:00pages
353-357issue
3eissn
0954-3007issn
1476-5640pii
ejcn2016256journal_volume
71pub_type
杂志文章,评审abstract：BACKGROUND/OBJECTIVES:B vitamins and related enzymes involved in one-carbon metabolism are necessary for DNA replication, DNA repair and regulation of gene expression. Disruption of one-carbon mechanism may affect cancer risk. We investigated prospectively the relationship between dietary intakes of methionine, B vitam...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2011.157
更新日期：2012-02-01 00:00:00
abstract：OBJECTIVE:The study was conducted to assess the relative validity of a 170-item semiquantitative food frequency questionnaire (SFFQ) adapted for use in the elderly. DESIGN AND SUBJECTS:The study was carried out in a sample of 80 men and women aged 55-75 y participating in a community based prospective cohort study in ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1600611
更新日期：1998-08-01 00:00:00
abstract：OBJECTIVE:This study describes the prevalence and characteristics of an elevated resting energy expenditure (REE) in patients with chronic obstructive pulmonary disease (COPD). DESIGN AND SETTING:Patients were consecutively admitted to an in-patient pulmonary rehabilitation centre. SUBJECTS:The study group consisted ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1600571
更新日期：1998-06-01 00:00:00
abstract：OBJECTIVES:To determine the resting metabolic rate in a sample of the Italian population, and to evaluate the validity of predictive equations for resting metabolic rate (RMR) from the literature in normal and obese subjects. DESIGN:Cross-sectional observational study. SETTINGS:Department of Human Physiology and Nutr...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601149
更新日期：2001-03-01 00:00:00
abstract：OBJECTIVE:To ascertain whether body mass index (BMI) cutoffs calculated according to age and pubertal stage are superior to BMI cutoffs calculated on the basis of age alone at correctly identifying children and adolescents with high levels of adiposity. DESIGN:Cross-sectional study. SETTING:Dunedin, a university city...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601608
更新日期：2003-06-01 00:00:00
abstract：:Anthropometric data available through National Nutrition Monitoring Bureau surveys/studies conducted by the National Institute for Nutrition were analysed to study body mass index (BMI:kg/m2) profiles of adults and relate them to various parameters such as the nutritional status of preschool children, socio-economic s...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,评审
doi：
更新日期：1994-11-01 00:00:00
abstract：BACKGROUND:Mediterranean diets are felt to be healthful diets linked with reduced mortality from diet-related noncommunicable diseases. OBJECTIVE:To examine trends in diet, activity, obesity and diet-related noncommunicable diseases for Spain and compare these with other European countries, particularly those from the...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601414
更新日期：2002-10-01 00:00:00
abstract：BACKGROUND:Famine exposure is a potential risk factor for adverse cardiometabolic health. However, the relationship between famine exposure during early life and carotid plaque in adulthood remains unclear. Therefore, the aim was to investigate the relationship between famine exposure during early life and the risks fo...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/s41430-020-00756-7
更新日期：2020-09-16 00:00:00
abstract：:Infant feeding pattern was studied longitudinally from birth to 52 weeks among all infants born in the period September 1982-December 1984 in three villages in Madura, East Java (n = 687). Genuine demand breast-feeding was practised but it is the custom to force-feed infants from as early as the third day after birth ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1991-02-01 00:00:00
abstract：:Watching television and playing video game being seated represent sedentary behaviours and increase the risk of weight gain and hypertension. We investigated the acute effects of violent and non-violent video-game playing on blood pressure (BP), appetite perception and food preferences. Forty-eight young, normal-weigh...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1038/ejcn.2013.180
更新日期：2013-12-01 00:00:00
abstract：:The paper reviews the evidence to date on the nutritional links with productivity and then goes on to provide results from a multi-country study on the effects of increasing body mass index (BMI) on productivity. The research relating nutritional status to work capacity is more consistent than the research linking nut...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,多中心研究,评审
doi：
更新日期：1994-11-01 00:00:00
abstract：OBJECTIVE:To analyse the relation between antioxidant vitamins A, E, and malondialdehyde (MDA) lipoperoxidation product plasma concentrations with incident dementia. DESIGN:: A nested case-control within the PAQUID (Personnes Agées QUID) cohort. SETTING:The PAQUID population-based prospective cohort in southwestern F...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601724
更新日期：2003-12-01 00:00:00
abstract：:It has been suggested that energy requirements are either proportional to the BMR (FAO/WHO/UNU, 1985) or to body weight (WHO, 1973). The present analysis sought to distinguish between these two possibilities by determining whether, in rural Gambian women, energy expenditure was more nearly proportional to the BMR or t...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,评审
doi：
更新日期：1988-11-01 00:00:00
abstract：OBJECTIVE:To estimate the current burden of mortality attributable to excess weight in the European Union (EU). METHODS:Prevalence of overweight (body mass index, BMI 25-29.9 kg/m(2)) and obesity (BMI >or=30 kg/m(2)) were based on self-reported data from a survey with samples representative of the 15 EU Member States ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601538
更新日期：2003-02-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Dysphagia is relatively common in patients with Parkinson disease (PD) and can have a negative impact on their quality of life; therefore, it is imperative that its prevalence in PD patients is studied. The aim of this study was to explore the prevalence and clinical correlation of dysphagia in Ch...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2017.100
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Recently, the role of a low-carbohydrate diet in diabetes management has generated interest with claims being made regarding its superiority over the traditional high-carbohydrate, low-fat dietary approach. This systematic review and meta-analysis evaluated the interpretation and effect of a low-c...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,meta分析
doi：10.1038/s41430-017-0019-4
更新日期：2018-03-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Anthropometric measurement is a noninvasive and cost-efficient method for nutritional assessment. The study aims to present age- and gender-specific anthropometric reference data for Swedish elderly in relation to common medical conditions, and also formulate prediction equations for such anthropo...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2015.73
更新日期：2015-09-01 00:00:00
abstract：OBJECTIVE:To assess if alcohol drinking is a risk factor for small for gestational age (SGA) birth. METHODS:Case-control study. Cases were 555 women (mean age 31 years, range 16-43) who delivered SGA babies at the Clinica Luigi Mangiagalli and the Obstetric and Gynecology Clinic of the University of Verona. The contro...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1602419
更新日期：2006-09-01 00:00:00
abstract：BACKGROUND:The relationship between hydrogen and methane production is a possible confounding factor in the interpretation of H(2) breath tests (HBT), but is usually disregarded for the interpretation of HBT and, in most instances, only H(2) excretion is measured. The present study was designed to evaluate the effect o...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601651
更新日期：2003-09-01 00:00:00
abstract：OBJECTIVE:To determine whether dual-energy X-ray absorptiometry (DXA) is a valid method for body composition assessment of obese and non-obese subjects. DESIGN:Cross-sectional study. SUBJECTS:Chinese women living in Hong Kong; 66 of 91 subjects had body mass index (BMI) of >25 kg/m2. MEASUREMENTS:Anthropometrics, in...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1600875
更新日期：1999-12-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:To clarify the association of serum docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) levels with cognitive decline over 10 years. SUBJECTS/METHODS:This study was part of the National Institute for Longevity Sciences - Longitudinal Study of Aging, and was conducted with 232 male and 198 ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2013.264
更新日期：2014-04-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:The term 'beer belly' expresses the common belief that beer consumption is a major determinant of waist circumference (WC). We studied the gender-specific associations between beer consumption and WC (partially in relation to body weight and hip circumference (HC) change). PARTICIPANTS/METHODS:Wi...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2009.39
更新日期：2009-09-01 00:00:00
abstract：OBJECTIVE:To assess the effects of supplementation with the carotenoids, beta-carotene or lycopene, at levels achievable within a diet rich in fruit and vegetables, on immune function in a group of free-living healthy elderly. DESIGN:A double-blind randomized placebo-controlled trial. T cell subsets and the expression...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1038/sj.ejcn.1601187
更新日期：2001-08-01 00:00:00
abstract：BACKGROUND:Children in China with Autism Spectrum Disorders (ASD) are prone to vitamin A deficiency (VAD). The present study compared two vitamin A supplements (VAS) in two groups of children with ASD and VAD to explore a better VAS program for children with ASD. METHOD:A total of 138 3-8-year-old children with ASD (1...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/s41430-020-00827-9
更新日期：2020-12-16 00:00:00
abstract：:Seven West African infants were studied prospectively from birth to 1 year to investigate factors affecting sleeping metabolic rate (SMR), particularly acute infection. There was no rise in SMR associated with acute infection, after adjustment for the effects of changes in body weight and body temperature. In the case...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1989-07-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Globally, fruit and vegetable intakes are well below recommendations despite ample evidence to link insufficient intake with increased risk of overweight and obesity. Intakes of fruits and vegetables in the general population differ between males and females, and although there is growing evidence...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1038/ejcn.2015.123
更新日期：2016-01-01 00:00:00
abstract：OBJECTIVE:To determine the origin of the poor digestibility of banana starch granules in the human small intestine. DESIGN:The subjects received the same experimental meal. SETTING:Nutrition Research Unit, Laënnec Hospital, CHU, Nantes. SUBJECTS:Six healthy young subjects. INTERVENTIONS:The digestion of raw green b...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1995-02-01 00:00:00
abstract：OBJECTIVE:This paper examines whether diet had changed at platforms in the Norwegian sector of the North Sea between 1985 and 1993 and if this was caused by nutrition promotive activities, including the use of a health handbook (HHB). DESIGN:The report is based on two cross-sectional surveys, one in 1985 and one in 19...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1995-12-01 00:00:00
abstract：OBJECTIVE:Reproducible and valid methods for measuring fruit and vegetable consumption among young school children are urgently needed. The aim of this study was to test the reproducibility and the validity of a newly developed questionnaire on the intake of fruit and vegetable among Norwegian 6th graders. The question...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601875
更新日期：2004-05-01 00:00:00
abstract：OBJECTIVE:To evaluate the effect of dosage on the metabolic response to vegetables added to a mixed lunch meal, and to relate the amounts to the tripartite plate model. Carrots were chosen as an example, and the carrots were blanched, frozen and boiled to include possible effects of processing and cooking. The effects ...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1994-06-01 00:00:00
