Abstract:
OBJECTIVE:To study the relationship between consumption of milk and milk products, calcium, lactose and vitamin D and occurrence of colorectal cancers. DESIGN:Prospective cohort study. SUBJECTS:A total of 9959 men and women aged 15 y or older without history of cancer at baseline. During a 24 y follow-up, 72 new cancers of the large bowel (38 in the colon and 34 in the rectum) were detected. RESULTS:Consumption of milk and total milk products was suggested to be inversely related to colon cancer incidence, whereas no similar association was seen for rectal cancer. The relative risk between the highest and lowest quartiles of intake adjusted for potential confounding factors was 0.46 (95% confidence interval 0.14-1.46, P for trend 0.09) for milk and 0.37 (95% CI=0.12-1.39, P for trend 0.06) for total milk products. Lactose intake showed a similar inverse relationship with colon cancer: the relative risk was 0.31 (95% CI=0.08-1.15, P for trend 0.03). Intake of vitamin D or total dietary calcium was not significantly related to colorectal cancer risk, whereas calcium provided by fermented milk products was associated with increased colorectal cancer incidence; in the highest quartile the multivariate adjusted relative risk for colorectal cancer was 2.07 (95% CI=1.00-4.28). CONCLUSIONS:Our results indicate that individuals showing high consumption of milk have a potentially reduced risk of colon cancer; however, the association does not appear to be due to intake of calcium, vitamin D, or to specific effects of fermented milk. SPONSORSHIP:This study was supported by a grant from the Swedish Cancer Foundation.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Järvinen R,Knekt P,Hakulinen T,Aromaa Adoi
10.1038/sj.ejcn.1601260subject
Has Abstractpub_date
2001-11-01 00:00:00pages
1000-7issue
11eissn
0954-3007issn
1476-5640journal_volume
55pub_type
杂志文章abstract:BACKGROUND/OBJECTIVES:We investigated whether C-reactive protein (CRP) as indicator of acute inflammation is associated with maximal isometric handgrip strength in non-critically ill patients. SUBJECTS/METHODS:Handgrip strength was measured with Jamar dynamometer in 620 hospitalized patients (56.4±15.9 years old, 52.3...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2013.261
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:To investigate the extent to which breast milk is replaced by intake of other liquids or foods, and to estimate energy intake of infants defined as exclusively (EBF), predominantly (PBF) and partially breast-fed (PartBF). DESIGN:Cross-sectional. SETTING:Community-based study in urban Pelotas, Southern Brazi...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601735
更新日期:2003-12-01 00:00:00
abstract::This study examined whether the association of household income with fresh fruit and vegetable consumption varies by the level of education. Data were derived from mail surveys carried out during 2000-2002 among 40- to 60-year-old employees of the City of Helsinki (n=8960, response rate 67%). Education was categorized...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2009.155
更新日期:2010-03-01 00:00:00
abstract::The present study tested the hypotheses that: (a) individual body composition estimates obtained with the Durnin-Womersley (D-W) equations have low validity in certain populations in developing countries; (b) there exists a poor relationship between the body mass index (BMI) and body composition estimates (fat mass (B...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1992-06-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to assess the major dietary patterns of two age cohorts of women, to determine to the extent to which the dietary patterns differ between the cohorts and to assess whether they vary according to sociodemographic and behavioural characteristics and patterns of nutrient intake. METHOD...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2010.121
更新日期:2010-10-01 00:00:00
abstract::Urea kinetics was measured in a single woman on five occasions over four years by the prime/intermittent oral-dose method with [15N15N]-urea. On a nitrogen intake of 231 +/- 24 mg/kg/day, urea production was 198 +/- 22 mg/kg/day, with the urinary excretion of urea being 143 +/- 25 mg/kg/day. Urea hydrolysis and salvag...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1991-07-01 00:00:00
abstract:OBJECTIVE:To investigate whether iron supplementation can improve thyroid hormone function in iron-deficient adolescent girls. DESIGN:A double-blind randomized intervention study. SETTING:The study was performed from 2002 through 2003 in the Islamic Republic of Iran. SUBJECTS:103 iron-deficient non-anaemic girls who...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1602349
更新日期:2006-04-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Prospective cohort studies have indicated that serum vitamin D levels are inversely related to risk of type 2 diabetes. However, such studies cannot determine the source of vitamin D. Therefore, we examined the association of dietary vitamin D intake with incident type 2 diabetes within the Europe...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,多中心研究
doi:10.1038/ejcn.2013.235
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the bifidogenic efficacy of two inulin doses in healthy human adults. DESIGN:A double-blind, placebo-controlled, crossover human study. SETTING:Food Microbial Sciences Unit, The University of Reading, Reading, UK. SUBJECTS:Thirty healthy volunteers, 15 men, 15 women (age range 19-35). INTERVEN...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1602636
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Additional strategies should be applied to optimize hospital food services, in order to increase the number of patients with adequate protein intake at mealtimes. Therefore, we aim to specify the differences in protein intake per mealtime between the traditional three meals a day food service (TMS...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-018-0288-6
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Food composition data (FCD) can provide important information in relation to diet and health; therefore, data on food composition have broad applications in health care. The objective of this study was to provide an overview of added-value eHealth systems that use modern information and communicat...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2010.222
更新日期:2010-11-01 00:00:00
abstract:OBJECTIVE:To assess the validity of two diet quality indexes-food variety score (FVS) and diet diversity score (DDS) in Western Mali. DESIGN:In two separate studies (A and B), FVS and DDS were derived from a food frequency questionnaire (FFQ) and were compared with the same scores and with measures of nutrient adequac...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601686
更新日期:2003-10-01 00:00:00
abstract:OBJECTIVES:To study the effect of supplementation with an association of small physiological amounts of antioxidant nutrients upon biochemical parameters and indicators of oxidative stress and antioxidant enzymes. DESIGN:The study included a double-blind placebo-controlled design. SETTING:Nursing homes in different a...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:1996-07-01 00:00:00
abstract::Dehydration is a reliable predictor of impaired cognitive status. Objective data, using tests of cortical function, support the deterioration of mental performance in mildly dehydrated younger adults. Dehydration frequently results in delirium as a manifestation of cognitive dysfunction. Although, the occurrence of de...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/sj.ejcn.1601898
更新日期:2003-12-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:The prolongation of healthy life expectancy (HALE) is a core issue of health policy in many countries. The purpose of this study is to clarify the relationship between dietary diversity and HALE using international databases. MATERIALS/METHODS:HALE data by country were derived from the Global Bur...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-018-0270-3
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVE:To examine the effect of acute fluid consumption on measures of impedance and percent body fat (%BF) using a common leg-to-leg bioelectrical impedance analyzer system. DESIGN:Cross-sectional design with treatment order determined using a counterbalanced assignment. SETTING:University laboratory. SUBJECTS:I...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1602282
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Longitudinal studies investigating dietary patterns (DPs) and their association with childhood overweight/obesity are lacking in Europe. We identified DPs and investigated their association with overweight/obesity and changes in body mass index (BMI) in a cohort of European children. SUBJECTS/MET...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,多中心研究
doi:10.1038/ejcn.2013.145
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Body composition assessment by computed tomography (CT) is increasingly used for diagnostic and prognostic purposes in various patient groups. This study aimed to compare the reliability and validity of a newly in-house developed segmentation software VikingSlice against a commercial software (Sli...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-018-0110-5
更新日期:2019-01-01 00:00:00
abstract::The fundamental principles of energy physiology were used to evaluate the validity of reported energy intake (EI) in 37 published dietary studies of adults providing 68 subgroups when classified according to sex and dietary method. EI was expressed as a multiple of BMR estimated using the reported heights and weights ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:
更新日期:1991-12-01 00:00:00
abstract:OBJECTIVE:To determine the effects of dietary consumption of Bifidobacterium lactis (strain HN019, DR10TM) on natural immunity. DESIGN:A randomized, double blind, placebo-controlled clinical trial. SETTING:Janeway Medical Centre, Memorial University, St Johns, Newfoundland. SUBJECTS:Twenty-five healthy elderly volun...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1600938
更新日期:2000-03-01 00:00:00
abstract::This paper was based on collaborative research efforts from Wageningen University and the University Medical Centre St Radboud in The Netherlands and describes the rationale for web-based nutrition counselling applications in general practice as well as some of the frequently used models and theories (predominantly th...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602185
更新日期:2005-08-01 00:00:00
abstract:OBJECTIVES:The content of n-3 (omega-3) polyunsaturated fatty acids in fat tissue is a valid indicator of their long-term consumption. We studied the stability of n-3 fatty acids in human subcutaneous fat microbiopsies after 6 and 11 y of storage. DESIGN:Microbiopsies were taken from a lump of human adipose tissue and...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601614
更新日期:2003-07-01 00:00:00
abstract:BACKGROUND:The prevalence of overweight and obesity in Mexican schoolchildren has increased in the past three decades. Dietary pattern approaches to assess diet have been used to study the relation between nutrition and chronic conditions. OBJECTIVE:The objective of this study is to analyze the association between die...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-020-0598-3
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Infant and young child feeding (IYCF) has not been documented in central and western China, where anaemia is prevalent. To support policy advocacy, we assessed IYCF and anaemia there using standardized methods. SUBJECTS/METHODS:A community-based, cross-sectional survey of 2244 children aged 6-23 ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2014.98
更新日期:2014-08-01 00:00:00
abstract:OBJECTIVE:We hypothesized that very low birth weight (VLBW) infants have reduced serum and red blood cell (RBC) selenium (Se) at birth, which decrease further with current nutrition and are associated with chronic lung disease and septicaemia. DESIGN:We studied Se intake, concentration in serum and RBCs and glutathion...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602715
更新日期:2008-03-01 00:00:00
abstract::The purpose of this paper is to assess the food habits of the Spanish population and the composition of the fat consumed. The national food survey data have been used. This survey was carried out during one week in a representative sample of households by means of recorded weighing or the household measures method. Th...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Recently, the role of a low-carbohydrate diet in diabetes management has generated interest with claims being made regarding its superiority over the traditional high-carbohydrate, low-fat dietary approach. This systematic review and meta-analysis evaluated the interpretation and effect of a low-c...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,meta分析
doi:10.1038/s41430-017-0019-4
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVES:This study aimed to examine the relationship between total pregnancy weight gain, maternal educational level, working status and infant birth weight among mothers and infants in urban health centers in Rasht, Iran. DESIGN:Pregnant women from six different public health centers in urban areas were studied in...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602239
更新日期:2005-10-01 00:00:00
abstract:OBJECTIVE:To investigate the possible differential role of refined and whole grain cereals on the risk of upper digestive and respiratory tract neoplasms. DESIGN:Hospital-based case-control study. SETTING:University Hospital of Lausanne, Switzerland. SUBJECTS:A total of 156 incident cases of cancers of the oral cavi...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601043
更新日期:2000-06-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to examine the variation of enterolactone from fasting and non-fasting blood of middle-aged healthy women eating a normal diet to determine the usefulness of a single sample in epidemiological studies. SUBJECTS AND METHODS:Twenty-six women born between 1940 and 1950 were recruited ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602811
更新日期:2008-08-01 00:00:00