Abstract:
OBJECTIVE:Adverse childhood experiences (ACEs) may have long-term consequences on at-risk behaviors that lead to an increased risk of sexually transmitted diseases (STDs) during adulthood. Therefore, we examined the relationship between ACEs and subsequent STDs for both men and women. METHODS:A total of 9323 (4263 men and 5060 women) adults >/=18 years of age participated in a retrospective cohort study evaluating the association between ACEs and self-reported STDs. Participants were adult members of a managed care organization who underwent routine medical evaluations and completed standardized questionnaires about 7 categories of ACEs, including emotional, physical, or sexual abuse; living with a battered mother; and living with a substance-abusing, mentally ill, or criminal household member. Logistic regression was used to model the association between the cumulative categories of ACEs (range: 0-7) and a history of STDs. RESULTS:We found that 59% (2986) of women and 57% (2464) of men reported 1 or more categories of adverse experiences during childhood. Among those with 0, 1, 2, 3, 4 to 5, and 6 to 7 ACEs, the proportion with STDs was 4.1%, 6.9%, 8.0%, 11.6%, 13.5%, and 20.7% for women and 7.3%, 10.9%, 12.9%, 17.1%, 17.1%, and 39.1% for men. After adjustment for age and race, all odds ratios for reporting an STD had confidence intervals that excluded 1. Among those with 1, 2, 3, 4 to 5, and 6 to 7 ACEs, the odds ratios were 1.45, 1.54, 2.22, 2. 48, and 3.40 for women and 1.46, 1.67, 2.16, 2.07, and 5.3 for men. CONCLUSIONS:We observed a strong graded relationship between ACEs and a self-reported history of STDs among adults.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Hillis SD,Anda RF,Felitti VJ,Nordenberg D,Marchbanks PAdoi
10.1542/peds.106.1.e11subject
Has Abstractpub_date
2000-07-01 00:00:00pages
E11issue
1eissn
0031-4005issn
1098-4275journal_volume
106pub_type
杂志文章相关文献
PEDIATRICS文献大全abstract:OBJECTIVES:We sought to determine the prevalence of corneal abrasions and possible associations with fingernail length, demographic information, sleeping, and crying among young infants. METHODS:Parents of 1- to 12-week-old infants without symptoms who were presenting for well-child visits completed a brief questionna...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2008-2023
更新日期:2010-03-01 00:00:00
abstract:OBJECTIVES:It has been shown that maternal prenatal exposure to selective serotonin reuptake inhibitors (SSRIs) may be a risk factor for attention-deficit/hyperactivity disorder (ADHD) in offspring. Our goal was to examine whether paternal SSRI use before conception increases the risk of ADHD in offspring. METHODS:On ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2017-1081
更新日期:2018-01-01 00:00:00
abstract::Two different tetravalent polysaccharide vaccines against group A, C, Y, and W135 meningococci were given to 118 infants aged 6 to 23 months; the same vaccines were administered in a second dose 12 months later to those infants aged 6 to 11 months at first vaccination. Forty of the infants received vaccine containing ...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1985-07-01 00:00:00
abstract:OBJECTIVE:To explore children's and parents' assessment of children's asthma. DESIGN:Prospective 2-month cohort study in which children and parents were reviewed at baseline and 1-month intervals. SETTING:Mid-sized, English-speaking, industrial community serving an urban and regional rural population. PATIENTS OR PA...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.99.2.165
更新日期:1997-02-01 00:00:00
abstract::Here we report an infant who had herpes simplex virus (HSV) encephalitis and sustained severe bilateral damage to the posterior frontal lobes, postcentral gyri, and the thalami despite intravenous acyclovir treatment. At 7 months of age, the patient developed infantile spasms and was treated with corticotropin injecti...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2005-1867
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:Stevens-Johnson syndrome (SJS) is an uncommon, sporadic disease and outbreaks are rare. In November 2013, an outbreak of SJS was identified at Children's Hospital Colorado. METHODS:Outbreak cases were children aged 5-21 with a discharge diagnosis of SJS admitted from September 1 to November 30, 2013. Medica...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2015-0278
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVE:To determine whether prenatal exposure to betamethasone for the prevention of neonatal respiratory distress syndrome (RDS) alters blood pressure in childhood. DESIGN:Prospective follow-up study of a randomized, double-blind, placebo-controlled trial. SETTING:National Women's Hospital (Auckland, New Zealand)...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1542/peds.2004-0196
更新日期:2004-09-01 00:00:00
abstract:BACKGROUND:Gestational age (GA) is frequently unknown or inaccurate in pregnancies in low-income countries. Early identification of preterm infants may help link them to potentially life-saving interventions. METHODS:We conducted a validation study in a community-based birth cohort in rural Bangladesh. GA was determin...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2015-3303
更新日期:2016-07-01 00:00:00
abstract::Thirty-two (18%) of 181 children cared for at our institution who were infected with the human immunodeficiency virus type 1 (HIV-1) were first seen, and HIV was diagnosed, when they were 4 years of age and older. Initial complaints or diagnoses for these children included the following: hematologic disorders (5) (3 i...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1992-11-01 00:00:00
abstract:OBJECTIVES:To develop and test an evidence-based model for reducing medication errors and harm in hospitalized children. METHODS:Prospective interrupted time series study evaluating the effectiveness of a multifaceted, staged intervention over 4 years in a major urban pediatric referral hospital. Guidelines for safe p...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2011-1902
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:To evaluate a simple, relatively inexpensive method using the fluid bed to provide high-intensity double-surface (HIDS) phototherapy and to confirm that the method described is more effective than conventional phototherapy (CPT) in the treatment of neonatal hyperbilirubinemia. DESIGN:Prospective controlled s...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章
doi:
更新日期:1995-06-01 00:00:00
abstract::In 1978 in the United States, 38 children aged 5 years or younger were killed when they fell from the passenger compartments of moving motor vehicles not involved in crashes. Twenty-eight children (74%) were boys. Eighteen (47%) were 2 years old; 35 (92%) were aged 1 to 3 years. Thirty-six children fell out through do...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1981-10-01 00:00:00
abstract::A randomized prospective study of the effect of medium-chain triglycerides (MCT) upon the absorption and retention of major minerals and nutrients, as well as upon 25-hydroxy vitamin D levels, was performed in low-birth-weight infants. Ten infants received a high-calcium and vitamin D-containing formula, which contain...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1983-07-01 00:00:00
abstract::In the last 20 years, two thirds of all new vaccines provided worldwide have been produced by a US network of independent industrial, governmental, and academic partners engaged in vaccine research and development. Vaccines are complex products and the science of vaccinology is difficult. To achieve the full promise o...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.100.6.1015
更新日期:1997-12-01 00:00:00
abstract:BACKGROUND:There is an increase in the incidence of type 2 diabetes in children and adolescents. Absence of known diabetes autoimmune markers is sometimes required to confirm the diagnosis. OBJECTIVE:To identify clinical and autoimmune characteristics of type 2 diabetes in a pediatric population. METHOD:We report an ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.107.6.e102
更新日期:2001-06-01 00:00:00
abstract::Early sexual intercourse among American adolescents represents a major public health problem. Although early sexual activity may be caused by a variety of factors, the media are believed to play a significant role. In film, television, and music, sexual messages are becoming more explicit in dialogue, lyrics, and beha...
journal_title:Pediatrics
pub_type: 指南,杂志文章
doi:10.1542/peds.107.1.191
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:Safety concerns for fluoroquinolones exist from animal studies demonstrating cartilage injury in weight-bearing joints, dependent on dose and duration of therapy. For children treated with levofloxacin or comparator in randomized, prospective, comparative studies for acute otitis media and community-acquired...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章
doi:10.1542/peds.2013-3636
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVES:Medication reconciliation errors on hospital admission can lead to significant patient harm. A pediatric intermediate care unit initiated a quality improvement project and aimed to reduce errors in admission medication reconciliation by 50% in 12 months. METHODS:From August 2017 to December 2018, a multidis...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2019-2464
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVES:We tested the hypotheses that apolipoprotein E genotype, in particular carriage of the epsilon4 allele, is more likely to be associated with cerebral palsy and that children with more severe neurologic impairment are more likely to carry this allele. METHODS:In this cross-sectional study, 209 children with ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2006-1083
更新日期:2007-02-01 00:00:00
abstract::Physicians who prescribe a new drug that has not been approved for a specific indication or a specific age group frequently find themselves in a quandary. Physicians who prescribe "old," time-honored drugs usually do not consult the package insert or search for US Food and Drug Administration (FDA) approval. This stat...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:1996-07-01 00:00:00
abstract::Clinicians have long recognized and attorneys have disputed that physical evidence of injury, sexually transmitted diseases, and seminal fluid are often absent in cases of child sexual abuse. To determine the frequency and significance of physical evidence in legally "proven" felony cases with penetration, a retrospec...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1989-12-01 00:00:00
abstract::An explicit goal of child health supervision visits is to gather information and provide guidance about the psychosocial problems of children and families. The purpose of this study was to determine the extent to which parents had opportunities to express psychosocial concerns and the nature of physicians' responses t...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1992-04-01 00:00:00
abstract::The recognition of fabricated illness (FI) in a child represents a diagnostic challenge. The suspicion of FI often arises from the discrepancy between laboratory tests and clinical history. For instance, (unnecessary) insulin injections by caregivers has been widely described as a common cause of factitious hypoglycem...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2014-4165
更新日期:2015-11-01 00:00:00
abstract:OBJECTIVE:Using an evidence-based approach, a Vermont Oxford Network focus group whose goal was to reduce brain injury developed and implemented a number of potentially better practices. Each center approached implementation of the practices differently. Reducing the incidence of intraventricular hemorrhage and periven...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:2003-04-01 00:00:00
abstract:OBJECTIVES:This is an investigation into the longitudinal patterns of bed sharing, the characteristics associated with those patterns, and the relationship with breastfeeding. METHODS:The study used prospective, population-based data from the United Kingdom to investigate nocturnal bed sharing at 5 time points from bi...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2010-1277
更新日期:2010-11-01 00:00:00
abstract::The fluorescence polarization of 116 amniotic fluid specimens obtained from 22 isoimmunized pregnant women was determined. The degree of fluorescence polarization of amniotic fluid provides an index of microvisocity in lipid aggregates that is dependent on the lecithin-to-sphingomyelin ratio and the degree of saturati...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1979-02-01 00:00:00
abstract:BACKGROUND:Overuse of antibiotics for children's upper respiratory infections is widespread and contributes to the emergence of antibiotic-resistant bacteria. OBJECTIVE:To assess changes in knowledge and awareness regarding antibiotic resistance and appropriate antibiotic use after community-wide educational intervent...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.107.1.e6
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVES:Postnatal survival rates of very low birth weight (VLBW) infants are well established for each birth weight or gestational age category. These figures do not differentiate viable infants who survive the first few days of life from extremely immature ones who die shortly after birth. This study aimed to devel...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2009-2810
更新日期:2010-08-01 00:00:00
abstract::Most family members who are evaluated as kidney donors for children have high reactivity in a mixed lymphocyte culture test and are thus excluded from donation. Fifty children, most of whom had highly reactive mixed lymphocyte cultures with their donors, were challenged with three blood transfusions from their donors ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1985-09-01 00:00:00
abstract:STUDY OBJECTIVES:To identify the sociodemographic and Health Belief Model predictors of follow-up appointment-keeping behavior. DESIGN:Prospective observational study. SETTINGS:General adolescent medical clinic. PATIENTS AND MEASUREMENTS:Sequential sample of 166 adolescents (aged 12 to 20 years, mean = 15.9 years) e...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1993-07-01 00:00:00