Abstract:
:An activity-guided separation for inhibitors of rat platelet 12-lipoxygenase led to the isolation of two compounds, 4-O-feruloyl-5-O-caffeoylquinic acid (IC50; 5.5 microM) and methyl 4-O-feruloyl-5-O-caffeoylquinate (IC50; 1.9 microM) from the peel of Ponkan fruit (Citrus reticulata). The complete structure of each phenolic ester was determined by NMR spectroscopy [1H and 13C NMR spectra, 1H-1H correlation spectroscopy (COSY), 1H-detected heteronuclear multiple quantum coherence (HMQC), and heteronuclear multiple bond connectivity (HMBC) spectroscopies] and other spectral methods.
journal_name
Phytochemistryjournal_title
Phytochemistryauthors
Nogata Y,Sekiya K,Ohta H,Kusumoto K,Ishizu Tdoi
10.1016/s0031-9422(00)00462-3subject
Has Abstractpub_date
2001-04-01 00:00:00pages
729-32issue
7eissn
0031-9422issn
1873-3700pii
S0031942200004623journal_volume
56pub_type
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