Modulation of diaspirin crosslinked hemoglobin induced systemic and regional hemodynamic response by ethanol in normal rats.

abstract：:The role of FSH in inducing folliculogenesis is well established. Recently, the availability of pure FSH has led to a reevaluation of its role in the process of ovulation. Previously, these functions have been examined separately, usually with pregnant mares' serum gonadotropin (PMSG) followed by FSH for ovulation or ...

journal_title：Life sciences

authors： Rice VC,Zusmanis K,Malter H,Mitchell-Leef D

更新日期：1993-01-01 00:00:00

abstract：:Recently, 4.4'-bis(1-p-carboxyphenyl-3-methyl-5-dydroxyl)-pyrazol (DRD156) has been developed as a new sensitive reagent that reacts specifically with singlet oxygen. The specificity of DRD156 for singlet oxygen in a biomimetic solution (micellar solution) and the effects of its coexistence with other reagent were exa...

journal_title：Life sciences

authors： Nishide N,Miyoshi N

更新日期：2002-12-06 00:00:00

abstract：:The impact of low level lead exposure on human central nervous system function is a major public health concern. This study addresses the inhibition of the cation pump enzyme Na, K-ATPase by low level lead. Human brain tissue was obtained at autopsy and frozen until use. Brain homogenates were preincubated with PbCl2 ...

journal_title：Life sciences

authors： Bertoni JM,Sprenkle PM

更新日期：1991-01-01 00:00:00

abstract：:To evaluate the relative contributions of the ovarian inhibin and estradiol-17 beta (E) on the regulation of FSH secretion, inhibin and E in ovarian venous plasma (OVP) and FSH and LH in peripheral plasma were simultaneously measured using superovulating rats with special reference to follicular maturation. By the tra...

journal_title：Life sciences

authors： Tsukamoto I,Taya K,Watanabe G,Sasamoto S

更新日期：1986-07-14 00:00:00

abstract：:Striatal D-2 dopamine (DA) antagonist and agonist binding sites were measured during the rat estrous cycle and compared to ovariectomized (OVX) rats. Dopaminergic D-2 antagonist binding sites were constant during the estrous cycle while agonist binding sites show a rapid and significant decrease of the ratio of high t...

journal_title：Life sciences

authors： Di Paolo T,Falardeau P,Morissette M

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Sepsis is a life-threatening organ dysfunction syndrome arising from uncontrolled inflammatory responses. Liver injury is a crucial factor for the prognosis of sepsis. Camptothecins (CPTs) have been reported to suppress the inflammatory response induced by sepsis. G2, a CPT-bile acid conjugate...

journal_title：Life sciences

authors： Xiao LX,Qi L,Zhang XL,Zhou YQ,Yue HL,Yu ED,Li QY

更新日期：2020-09-15 00:00:00

abstract：:Brown adipose tissue (BAT) has multiple functions in the human body, including the production of heat and increasing energy consumption. However, BAT is also related to many kinds of diseases, such as obesity and metabolic disorders. The progression of such diseases occurs at the cellular level, and thus, imaging tech...

journal_title：Life sciences

authors： Gu J,Wang X,Yang H,Li H,Wang J

更新日期：2020-05-15 00:00:00

abstract：:The Sertoli cells play an essential role in the maintenance and control of spermatogenesis. The ecto-nucleoside triphosphate diphosphohydrolase (E-NTPDase) and 5'-nucleotidase activities can modulate the extracellular adenine nucleotide levels, controlling nucleotide-mediated signaling events in Sertoli cells. Since t...

journal_title：Life sciences

authors： Zamoner A,Bruno AN,Casali EA,Corbelini PF,Diniz GP,Barreto-Chaves ML,Silva FR,Sarkis JJ,Pessoa-Pureur R

更新日期：2006-12-03 00:00:00

abstract：:Bromopride (BRO) and domperidone (DOMP) are dopamine D2 blocking agents used in gastroenterology clinics because of their anti emetic effect as well as their central and peripheral actions of increasing gastrointestinal motor activity. The rationale for these experiments was to compare BRO- and DOMP-effects on plasma,...

journal_title：Life sciences

authors： Nasello AG,Gidali D,de Sá-Rocha LC,Felicio LF

更新日期：1995-01-01 00:00:00

abstract：:The anti-secretory activity of the competitive H2-antagonist HUK 978 was determined in rat, guinea-pig and dog. In all systems examined, HUK 978 was more potent than cimetidine and ranitidine both intravenously and orally. In addition, the compound at approximately equipotent doses as these established H2-antagonists ...

journal_title：Life sciences

authors： Coombes JD,Norris DB,Rising TJ,Ross BC,Steward A

更新日期：1985-11-04 00:00:00

abstract：:Administration of a high dose of hydrocortisone hemisuccinate sodium (0.25 mumol/egg) to 15-day-old fertilized hen's eggs caused accumulation of biliverdin in the embryonic liver. The responses were 10 to 20-fold higher than controls within 48 hr as a result of stimulation of biliverdin synthesis in the liver and the ...

journal_title：Life sciences

authors： Nishigori H,Ishida O,Ogihara-Umeda I

更新日期：1993-01-01 00:00:00

abstract：:Acute and chronic opiate exposure impairs the emptying of bile from the gallbladder. In this study, the effects of a 4-day morphine regimen on bile composition were examined. Bile acids and phospholipids concentration of bile obtained from the gallbladder of female morphine-treated (MT) guinea pigs were reduced by 60%...

journal_title：Life sciences

authors： Malave A,Kuta C,Yim GW

更新日期：1993-01-01 00:00:00

abstract：:The influence of stressful experiences on the development of vacuous chewing movements (VCM) was investigated in non-medicated rats. After an initial baseline period one group of rats was housed in a noisy environment while another group was housed in quiet surroundings. The development of VCM was recorded during a 16...

journal_title：Life sciences

authors： Glenthøj B,Hemmingsen R

更新日期：1991-01-01 00:00:00

abstract：:Using a ligation method, rat rectal epithelium was exposed to 2% sodium salicylate, and light and electron microscopic methods were used to assay for: 1) permeability of the epithelium to a marker dye, trypan blue, and 2) damage expressed in terms of disruption of the epithelial surface. Rectal mucosa was exposed to s...

journal_title：Life sciences

authors： Sithigorngul P,Burton P,Nishihata T,Caldwell L

更新日期：1983-09-12 00:00:00

abstract：AIMS:Cancer Stem Cells (CSCs) refers to heterogeneous tumor cells retaining the abilities of self-renewal and differentiation. This study used mRNAsi, which is an index to describe the similarity between tumor cells and CSCs, to define genes involved in endometrial carcinoma. MATERIALS AND METHODS:The mRNA expression ...

journal_title：Life sciences

authors： Liu J,Wu Z,Sun R,Nie S,Meng H,Zhong Y,Nie X,Cheng W

更新日期：2020-10-01 00:00:00

abstract：:We had previously hypothesized that linoleic acid (LA) was essential for development of alcoholic induced liver injury in our rat model. Male Wistar rats were fed a nutritionally adequate diet (25% calories as fat) with ethanol (8-17 g/kg/day). The source of fat was tallow (0.7% LA), lard (2.5% LA) or tallow supplemen...

journal_title：Life sciences

authors： Nanji AA,French SW

更新日期：1989-01-01 00:00:00

abstract：AIMS:Head and neck squamous cell carcinoma (HNSCC) is an highly aggressive tumor with heterogeneous prognosis. We here report that immune-related genes (IRGs) could effectively distinguish prognostically different HNSCC patients. MATERIALS AND METHODS:MRNA levels of 1333 IRGs that from ImmPort database in HNSCC sample...

journal_title：Life sciences

authors： Yang J,Xie K,Li C

更新日期：2020-09-01 00:00:00

abstract：AIMS:Ganoderma lucidum, a traditional Chinese medicine, is well known as a modulator of functions of the immune system as well as an anti-tumour agent. However, its active compounds and their molecular mechanisms of action are not well established. GLIS, a proteoglycan isolated from the fruiting body of G. lucidum, sti...

journal_title：Life sciences

authors： Zhang J,Tang Q,Zhou C,Jia W,Da Silva L,Nguyen LD,Reutter W,Fan H

更新日期：2010-11-20 00:00:00

abstract：:We developed an experimental model to study the effect of daily cocaine administration on the mucosal immune system during murine acquired immune deficiency syndrome (MAIDS). Mice were infected with LP-BM5 murine leukemia virus, a retrovirus which causes immunosuppression with development of functional murine AIDS. Mi...

journal_title：Life sciences

authors： Lopez MC,Watson RR

更新日期：1994-01-01 00:00:00

abstract：:Aluminum (Al) is thought to be a risk factor for neurodegenerative disorders, but the molecular mechanism has been not clarified yet. In this study, we examined how a transport system handled transport of Al citrate, the major Al species in brain, and effect of Al citrate treatment on expression of the transporter and...

journal_title：Life sciences

authors： Nagasawa K,Akagi J,Koma M,Kakuda T,Nagai K,Shimohama S,Fujimoto S

更新日期：2006-05-30 00:00:00

abstract：:There is now some evidence that i) the availability of plasma tryptophan, the precursor of serotonin, is significantly lower in pregnant women at the end of term and the first few days after delivery than in nonpregnant women; and ii) both pregnancy and the early puerperium are accompanied by activation of the inflamm...

journal_title：Life sciences

authors： Maes M,Verkerk R,Bonaccorso S,Ombelet W,Bosmans E,Scharpé S

更新日期：2002-09-06 00:00:00

abstract：:Nitric oxide (NO) is present in the exhaled breath of humans and experimental animals, but its physiologic role and cellular source(s) remain to be determined. Possible sites of origin are pulmonary endothelial cells and/or resident macrophages. Here we have tested the hypothesis that changes in cardiovascular status ...

journal_title：Life sciences

authors： Bauer JA,Wald JA,Doran S,Soda D

更新日期：1994-01-01 00:00:00

abstract：:Vascular endothelial cells have been found to produce a relaxant mediator, identified as nitric oxide (NO) and implicated in numerous physiological functions. Subsequently, there has been an intensive search for accurate and specific detection methods to measure biological NO production. In the present study, we compa...

journal_title：Life sciences

authors： Privat C,Lantoine F,Bedioui F,Millanvoye van Brussel E,Devynck J,Devynck MA

更新日期：1997-01-01 00:00:00

abstract：:The concept of food has expanded beyond its traditional role of survival and hunger satisfaction, to include a role in the prevention and treatment of disease. Polyphenols are classes of compounds that are synthesized by plants to serve a wide variety of functions including growth pollination and defense. These compou...

journal_title：Life sciences

authors： Raj P,Louis XL,Thandapilly SJ,Movahed A,Zieroth S,Netticadan T

更新日期：2014-01-30 00:00:00

abstract：:Autophagy is considered as an important intracellular mechanism that degrades cytoplasmic components to furnish additional energy. It has cytoprotective effects through the degradation of intracellular pathogens, damaged organelles, and protein aggregates. On the other hand, there are reports of an association between...

journal_title：Life sciences

authors： Karami J,Masoumi M,Khorramdelazad H,Bashiri H,Darvishi P,Sereshki HA,Shekarabi M,Sahebkar A

更新日期：2020-08-01 00:00:00

abstract：AIMS:A growing body of evidence shows the cardiovascular benefits of fish oil ingredients, including eicosapentaenoic acid (EPA), in humans and experimental animals. However, the effects of EPA on endothelin (ET)-1-induced cardiomyocyte hypertrophy and the involved signaling cascade are largely unknown. A previous stud...

journal_title：Life sciences

authors： Shimojo N,Jesmin S,Sakai S,Maeda S,Miyauchi T,Mizutani T,Aonuma K,Kawano S

更新日期：2014-11-24 00:00:00

abstract：:The effects of the cannabinoid receptor agonist Win 55,212-2 and of the competitive cannabinoid receptor antagonist SR 141716A on the electrically-evoked peristalsis of isolated distal colon of mouse were studied. Intraluminal pressure, longitudinal displacement, ejected fluid volume and changes in morphology of exter...

journal_title：Life sciences

authors： Mancinelli R,Fabrizi A,Del Monaco S,Azzena GB,Vargiu R,Colombo GC,Gessa GL

更新日期：2001-05-25 00:00:00

abstract：:Liquid chromatography of porcine duodenal extracts, in conjugation with bioassay on guinea-pig ileum myenteric plexus longitudinal muscle preparation, yielded substances which inhibited electrically-evoked twitches of the preparations, but whose actions could not be reversed by naloxone, an opioid antagonist. The subs...

journal_title：Life sciences

authors： Arakawa Y,Tachibana S

更新日期：1984-12-17 00:00:00

abstract：:We examined the effects of estrogen, 12-O-tetradecanoylphorbol 13 acetate (TPA), and lipopolysaccharide (LPS) on the gene expression of platelet-derived growth factor (PDGF) by the monocyte/macrophage cell line, THP-1. THP-1 cells were exposed to TPA for 48 or 96 hours to induce differentiation. Some were treated with...

journal_title：Life sciences

authors： Shanker G,Sorci-Thomas M,Adams MR

更新日期：1995-01-01 00:00:00

abstract：:Further confirmation that the LHRH/LHRH agonist-induced ovulation in the hypophysectomized (hypx) rat is due to a direct ovarian effect and not mediated by LH release from residual pituitary tissue or other CNS sites is provided by the persistence of this effect despite concomitant median eminence lesion or passive im...

journal_title：Life sciences

authors： Bex FJ,Corbin A

更新日期：1984-08-27 00:00:00