Abstract:
:Liquid chromatography of porcine duodenal extracts, in conjugation with bioassay on guinea-pig ileum myenteric plexus longitudinal muscle preparation, yielded substances which inhibited electrically-evoked twitches of the preparations, but whose actions could not be reversed by naloxone, an opioid antagonist. The substances were determined to be NH2-terminally extended forms of somatostatin, i.e. somatostatin-28, somatostatin-25 and somatostatin-20. This is the first time that somatostatin-20 has been isolated from animal tissues.
journal_name
Life Scijournal_title
Life sciencesauthors
Arakawa Y,Tachibana Sdoi
10.1016/0024-3205(84)90439-9subject
Has Abstractpub_date
1984-12-17 00:00:00pages
2529-36issue
25eissn
0024-3205issn
1879-0631pii
0024-3205(84)90439-9journal_volume
35pub_type
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