Diabetes with the 3243 mitochondrial tRNALeu(UUR) mutation. Characteristic neuroimaging findings.

abstract：OBJECTIVE:To investigate the association of carotid atherosclerosis and serum lipoprotein(a) [Lp(a)] concentrations in subjects with NIDDM. RESEARCH DESIGN AND METHODS:We measured carotid intima-media thickness (IMT) and Lp(a) concentrations in 117 NIDDM subjects. Subjects were divided into tertiles according to IMT v...

journal_title：Diabetes care

authors： Yamamoto M,Egusa G,Yamakido M

更新日期：1997-05-01 00:00:00

abstract：OBJECTIVE:To estimate the prevalence of severe diabetic complications. RESEARCH DESIGN AND METHODS:We surveyed the data systems of the IHS and local care providers to identify all AI/AN people with any of three diabetic complications: retinopathy needing one or more laser treatments, ESRD needing dialysis, and one or ...

journal_title：Diabetes care

authors： Freeman WL,Hosey GM

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:To examine the hypothesis that hyperinsulinemia among relatives of NIDDM probands will increase the prevalence of DLPs, we measured insulin levels and examined the frequency of DLPs among NIDDM pedigree members. RESEARCH DESIGN AND METHODS:We performed 2-h 75-g OGTTs and measured lipid and insulin levels of ...

journal_title：Diabetes care

authors： Schumacher MC,Maxwell TM,Wu LL,Hunt SC,Williams RR,Elbein SC

更新日期：1992-10-01 00:00:00

abstract：:Since little is known regarding the appropriate time for preprandial insulin administration, we compared the effects of 30-min subcutaneous insulin infusions started 60 min, 30 min, and immediately before meal ingestion on postprandial plasma glucose and insulin profiles in eight subjects with insulin-dependent diabet...

journal_title：Diabetes care

authors： Dimitriadis GD,Gerich JE

更新日期：1983-07-01 00:00:00

abstract：OBJECTIVE:Large subcutaneous fat cells associate with insulin resistance and high risk of developing type 2 diabetes. We investigated if changes in fat cell volume and fat mass correlate with improvements in the metabolic risk profile after bariatric surgery in obese patients. RESEARCH DESIGN AND METHODS:Fat cell volu...

journal_title：Diabetes care

authors： Andersson DP,Eriksson Hogling D,Thorell A,Toft E,Qvisth V,Näslund E,Thörne A,Wirén M,Löfgren P,Hoffstedt J,Dahlman I,Mejhert N,Rydén M,Arner E,Arner P

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:To investigate whether microalbuminuria is associated with markers of the acute-phase response in NIDDM and whether there are ethnic differences in this association among the three main racial groups in Malaysia. RESEARCH DESIGN AND METHODS:NIDDM patients of Chinese, Indian, and Malay origin attending a diab...

journal_title：Diabetes care

authors： Islam N,Kazmi F,Chusney GD,Mattock MB,Zaini A,Pickup JC

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVE:To determine the association between triglyceride levels and lower-extremity amputation (LEA) risk in a large diabetic cohort. RESEARCH DESIGN AND METHODS:This is a 10-year survey follow-up study (from 1995-2006) of 28,701 diabetic patients with a baseline triglyceride measure. All patients were fully insure...

journal_title：Diabetes care

authors： Callaghan BC,Feldman E,Liu J,Kerber K,Pop-Busui R,Moffet H,Karter AJ

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:This study uses novel methods to examine the frequency of diagnosis and treatment of prediabetes in real-world clinical settings using electronic health record (EHR) data. RESEARCH DESIGN AND METHODS:We identified a cohort of 358,120 adults with incident prediabetes (fasting plasma glucose [FPG] 100-125 mg/d...

journal_title：Diabetes care

authors： Schmittdiel JA,Adams SR,Segal J,Griffin MR,Roumie CL,Ohnsorg K,Grant RW,O'Connor PJ

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:There is suggestive evidence linking hypoglycemia with cardiovascular disease, but few data have been collected in a community-based setting. Information is lacking on individual cardiovascular outcomes and cause-specific mortality. RESEARCH DESIGN AND METHODS:We conducted a prospective cohort analysis of 1,...

journal_title：Diabetes care

authors： Lee AK,Warren B,Lee CJ,McEvoy JW,Matsushita K,Huang ES,Sharrett AR,Coresh J,Selvin E

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:PANORAMA, a nine-country cross-sectional type 2 diabetes study, investigated factors associated with quality of life (QoL), health status, and other patient-reported outcome measures (PROMs). RESEARCH DESIGN AND METHODS:Patients were randomly or consecutively selected from primary/secondary care. PROMs inclu...

journal_title：Diabetes care

authors： Bradley C,Eschwège E,de Pablos-Velasco P,Parhofer KG,Simon D,Vandenberghe H,Gönder-Frederick L

更新日期：2018-02-01 00:00:00

abstract：:This study describes and characterizes a putative sulfonylurea receptor. The radioligand used was [3H]glipizide (9 Ci/mmol). The beta-cell plasma membranes were derived from a transplantable rat insulinoma generated by subcutaneous injection of RINm5F cells and purified by ultracentrifugation on a 15-55% sucrose gradi...

journal_title：Diabetes care

authors： Siconolfi-Baez L,Banerji MA,Lebovitz HE

更新日期：1990-08-01 00:00:00

abstract：OBJECTIVE:Diabetes eliminates the protective effect of female sex on the risk of coronary heart disease (CHD). We assessed sex differences in the treatment of CHD risk factors among patients with diabetes. RESEARCH DESIGN AND METHODS:A cross-sectional analysis included 3,849 patients with diabetes treated in five acad...

journal_title：Diabetes care

authors： Wexler DJ,Grant RW,Meigs JB,Nathan DM,Cagliero E

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:Bimodality in the distribution of glucose has been used to define the cut point for the diagnosis of diabetes. Previous studies on bimodality have primarily been in populations with a high prevalence of type 2 diabetes, including one study in a white Caucasian population. All studies included participants wit...

journal_title：Diabetes care

authors： Vistisen D,Colagiuri S,Borch-Johnsen K,DETECT-2 Collaboration.

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:To characterize metabolic effects of troglitazone in type 2 diabetic, obese, and lean subjects, and examine the effects of troglitazone 2-3 weeks after discontinuation. RESEARCH DESIGN AND METHODS:Nine type 2 diabetic, nine obese, and nine lean subjects underwent baseline metabolic studies including an 8-h m...

journal_title：Diabetes care

authors： Frias JP,Yu JG,Kruszynska YT,Olefsky JM

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:Patients with diabetes have a higher case fatality rate in myocardial infarction (MI) or stroke than those without diabetes: that is, MI and stroke are more often fatal if diabetes is present. We investigated whether the risk of MI or stroke being fatal in type 2 diabetes can be estimated using information av...

journal_title：Diabetes care

authors： Stevens RJ,Coleman RL,Adler AI,Stratton IM,Matthews DR,Holman RR

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:Endothelial markers endothelin 1 (ET-1) and von Willebrand factor (vWF) were assessed in patients with type 2 diabetes and dyslipidemia and in patients with hypercholesterolemia. RESEARCH DESIGN AND METHODS:In this case-control study, plasma ET-and vWF levels were measured by enzyme-linked immunosorbent assa...

journal_title：Diabetes care

authors： Seligman BG,Biolo A,Polanczyk CA,Gross JL,Clausell N

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of flexible intensive insulin therapy (FIIT) and an automated bolus calculator (ABC) in a Danish type 1 diabetes population treated with multiple daily injections. Furthermore, to test the feasibility of teaching FIIT in a 3-h structured course. RESEARCH DESIGN AND METHODS:The Bolus...

journal_title：Diabetes care

authors： Schmidt S,Meldgaard M,Serifovski N,Storm C,Christensen TM,Gade-Rasmussen B,Nørgaard K

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:It is still controversial whether sirolimus-eluting stent (SES) and paclitaxel-eluting stent (PES) are equally effective in patients with diabetes. In these patients, multiple individual variables may be responsible for neointimal hyperplasia, thus making difficult the comparison of the two drug-eluting stent...

journal_title：Diabetes care

authors： Tomai F,Reimers B,De Luca L,Galassi AR,Gaspardone A,Ghini AS,Ferrero V,Favero L,Gioffrè G,Prati F,Tamburino C,Ribichini F

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the relationship between preoperative A1C and clinical outcomes in individuals with diabetes mellitus undergoing noncardiac surgery. RESEARCH DESIGN AND METHODS:Data were obtained from the National Surgical Quality Improvement Program database and the Research Patient Data Registry of the Brigham...

journal_title：Diabetes care

authors： Underwood P,Askari R,Hurwitz S,Chamarthi B,Garg R

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:The impact of major affective disorders on the effectiveness of diabetes prevention programs at promoting health behaviors has not been established. We investigated whether depression modifies the effectiveness of two pragmatic diabetes prevention programs at promoting increased physical activity. RESEARCH D...

journal_title：Diabetes care

authors： Yates T,Gray LJ,Henson J,Edwardson CL,Khunti K,Davies MJ

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:To examine the association of renal function in diabetic patients with apolipoprotein (apo) E polymorphism. RESEARCH DESIGN AND METHODS:Apo E genotypes, lipid and lipoprotein serum levels, creatinine clearance (CCr), and excretion of marker proteins were determined in German type 1 (IDDM; n = 162) and type 2...

journal_title：Diabetes care

authors： Werle E,Fiehn W,Hasslacher C

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVE:To study the influence of position changes on 24-h ambulatory blood pressure (ABP) in normotensive or mildly hypertensive normoalbuminuric patients with type 1 diabetes. RESEARCH DESIGN AND METHODS:A cross-sectional evaluation of patients was staged according to the duration of diabetes (DD) and the presence...

journal_title：Diabetes care

authors： Benhamou PY,Mouret S,Quesada JL,Boizel R,Baguet JP,Halimi S,Mallion JM

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of metformin on glycemic control, insulin resistance, and risk factors for cardiovascular disease in NIDDM subjects from two ethnic groups (Caucasian and Asian) with different risks of cardiovascular disease. RESEARCH DESIGN AND METHODS:A total of 27 subjects with NIDDM (17 Caucasi...

journal_title：Diabetes care

authors： Nagi DK,Yudkin JS

更新日期：1993-04-01 00:00:00

abstract：OBJECTIVE:To summarize the efficacy of metformin in reducing BMI and cardiometabolic risk in obese children and adolescents without diabetes. RESEARCH DESIGN AND METHODS:We performed a systematic review and meta-analysis of randomized controlled trials (RCTs). Double-blind RCTs of > or =6 months duration in obese subj...

journal_title：Diabetes care

authors： Park MH,Kinra S,Ward KJ,White B,Viner RM

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:To evaluate the utility of a semipermeable polymeric membrane dressing for the treatment of chronic diabetic foot ulcers. RESEARCH DESIGN AND METHODS:Nineteen subjects with either insulin-dependent diabetes mellitus (IDDM) or non-insulin-dependent diabetes mellitus (NIDDM) and foot ulcers were randomly assig...

journal_title：Diabetes care

authors： Blackman JD,Senseng D,Quinn L,Mazzone T

更新日期：1994-04-01 00:00:00

abstract：OBJECTIVE:High-deductible health plans (HDHPs) are now the predominant commercial health insurance benefit in the U.S. We sought to determine the effects of HDHPs on emergency department and hospital care, adverse outcomes, and total health care expenditures among patients with diabetes. RESEARCH DESIGN AND METHODS:We...

journal_title：Diabetes care

authors： Wharam JF,Zhang F,Eggleston EM,Lu CY,Soumerai SB,Ross-Degnan D

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:This study was performed to evaluate whether an additional dose of NPH insulin at lunchtime might overcome the deleterious effects of waning basal insulinemia on pre-dinner and evening glucose values during insulin lispro intensive therapy with once daily basal insulin at night. RESEARCH DESIGN AND METHODS:T...

journal_title：Diabetes care

authors： Stades AM,Hoekstra JB,van den Tweel I,Erkelens DW,Holleman F,STABILITY Study Group.

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVE:To determine whether low-glycemic index (GI) diets have clinical utility in overweight patients with non-insulin-dependent diabetes mellitus (NIDDM). RESEARCH DESIGN AND METHODS:Six patients with NIDDM were studied on both high- and low-GI diets of 6-wk duration with metabolic diets with a randomized crossov...

journal_title：Diabetes care

authors： Wolever TM,Jenkins DJ,Vuksan V,Jenkins AL,Wong GS,Josse RG

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVE:1) To examine trends in the use of diabetes medications and 2) to determine whether physicians individualize diabetes treatment as recommended by the American Diabetes Association (ADA). RESEARCH DESIGN AND METHODS:We conducted a retrospective, cross-sectional analysis of 2003-2016 National Health and Nutrit...

journal_title：Diabetes care

authors： Le P,Chaitoff A,Misra-Hebert AD,Ye W,Herman WH,Rothberg MB

更新日期：2020-06-01 00:00:00

abstract：OBJECTIVE:We investigated the effect of glimepiride, a third-generation sulfonylurea hypoglycemic agent, on insulin resistance in elderly patients with type 2 diabetes, in connection with plasma adiponectin and 8-epi-prostagrandin F2alpha (8-epi-PGF2alpha), an oxidative stress marker. RESEARCH DESIGN AND METHODS:A tot...

journal_title：Diabetes care

authors： Tsunekawa T,Hayashi T,Suzuki Y,Matsui-Hirai H,Kano H,Fukatsu A,Nomura N,Miyazaki A,Iguchi A

更新日期：2003-02-01 00:00:00