Characterization and significance of sulfonylurea receptors.

abstract：OBJECTIVE:To assess the prognostic role of ambulatory 24-h pulse pressure (PP) on various vascular events in relatively young type 2 diabetic subjects under 60 years of age. RESEARCH DESIGN AND METHODS:In this prospective study, 237 type 2 diabetic subjects without any history of vascular complications were analyzed. ...

journal_title：Diabetes care

authors： Nakano S,Konishi K,Furuya K,Uehara K,Nishizawa M,Nakagawa A,Kigoshi T,Uchida K

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:Physical activity is integral to the management of type 2 diabetes. Unfortunately, the majority of adults with type 2 diabetes do not regularly engage in physical activity. The purpose of this study was to assess physical activity behavior and its correlates (i.e., physical activity knowledge, barriers, and p...

journal_title：Diabetes care

authors： Hays LM,Clark DO

更新日期：1999-05-01 00:00:00

abstract：OBJECTIVE:Youth with type 1 diabetes face long-term risks of health complications of the disease. Little is known about patients' and parents' knowledge, acquisition of information, and family communication regarding these complications. This paper reports qualitative analyses of parental focus-group discussions of thi...

journal_title：Diabetes care

authors： Buckloh LM,Lochrie AS,Antal H,Milkes A,Canas JA,Hutchinson S,Wysocki T

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVE:To provide a description of the clinical characteristics that distinguish individuals who withhold insulin for weight control from those who do not. Some individuals with insulin-dependent diabetes mellitus (IDDM) control their weight by withholding insulin and purging excessive calories. This process places ...

journal_title：Diabetes care

authors： Biggs MM,Basco MR,Patterson G,Raskin P

更新日期：1994-10-01 00:00:00

abstract：:OBJECTIVE We tested whether average monthly glycemic burden (AMGB), a marker of hyperglycemia that is a function of the extent and duration that A1C exceeded 7%, indicated greater risk of cardiovascular disease (CVD) than traditional A1C measures. RESEARCH DESIGN AND METHODS Using a case-control design, we studied 2,4...

journal_title：Diabetes care

authors： Nichols GA,Rosales AG,Perrin NA,Fortmann SP

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to compare different outcome measures in the audit of management of diabetic foot ulcers RESEARCH DESIGN AND METHODS:Data collected prospectively in a consecutive cohort of patients referred to a specialist multidisciplinary foot care clinic between 1 January 2000 and 31 Decembe...

journal_title：Diabetes care

authors： Jeffcoate WJ,Chipchase SY,Ince P,Game FL

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVE:To evaluate to what extent the association between family history of diabetes and risk of type 2 diabetes can be explained by excess adiposity and lifestyle risk factors. RESEARCH DESIGN AND METHODS:We analyzed data from 73,227 women who participated in the Nurses' Health Study cohort. A family history of di...

journal_title：Diabetes care

authors： van 't Riet E,Dekker JM,Sun Q,Nijpels G,Hu FB,van Dam RM

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:To explore the nature of functional impairment in older people with diabetes. RESEARCH DESIGN AND METHODS:A population-based case-control study with detailed assessment of diabetes and functional status was undertaken. RESULTS:Altogether, 403 case subjects and 403 matched control subjects were studied (medi...

journal_title：Diabetes care

authors： Sinclair AJ,Conroy SP,Bayer AJ

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to compare measurements of glucose obtained via iontophoretic extraction with the GlucoWatch automatic glucose biographer (Cygnus, Inc., Redwood City, CA) with capillary blood glucose values that were determined 1) in a controlled outpatient clinic setting and 2) in a home settin...

journal_title：Diabetes care

authors： Garg SK,Potts RO,Ackerman NR,Fermi SJ,Tamada JA,Chase HP

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVE:Glycemic control (HbA(1c) [A1C]) is strongly associated with microvascular disease in individuals with diabetes, but its relation to macrovascular disease and atherosclerosis is less clear. This study examines the relationship between A1C, carotid intima-media thickness (IMT), and traditional cardiovascular r...

journal_title：Diabetes care

authors： Selvin E,Coresh J,Golden SH,Boland LL,Brancati FL,Steffes MW,Atherosclerosis risk in communities study.

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVE:To determine the occurrence of elevated fetal hemoglobin (HbF) among the diabetic population and determine the clinical situation of importance. RESEARCH DESIGN AND METHODS:A cross-sectional study was conducted. HbA1c and HbF were measured with high-performance liquid chromatography in 1,104 consecutive diab...

journal_title：Diabetes care

authors： Koskinen LK,Lahtela JT,Koivula TA

更新日期：1994-08-01 00:00:00

abstract：OBJECTIVE:To examine the prevalence of cardiovascular disease in diabetic patients as a function of apolipoprotein (apo) E polymorphism. RESEARCH DESIGN AND METHODS:The apo E phenotypes and plasma lipid, lipoprotein, and apo levels were determined for 517 Italian diabetic patients. The prevalence of cardiovascular dis...

journal_title：Diabetes care

authors： Boemi M,Sirolla C,Amadio L,Fumelli P,Pometta D,James RW

更新日期：1995-04-01 00:00:00

abstract：OBJECTIVE:To implement an educational program in 10 Latin American countries and to evaluate its effect on the clinical, biochemical, and therapeutic aspects as well as the economic cost of diabetes. RESEARCH DESIGN AND METHODS:Educators from each participating country were previously trained to implement the educatio...

journal_title：Diabetes care

authors： Gagliardino JJ,Etchegoyen G,PENDID-LA Research Group.

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVE:To determine whether biomarkers of inflammation and endothelial dysfunction are associated with the development of kidney dysfunction and the time frame of their association. RESEARCH DESIGN AND METHODS:Biomarkers were measured at four time points during 28 years of treatment and follow-up in patients with t...

journal_title：Diabetes care

authors： Baker NL,Hunt KJ,Stevens DR,Jarai G,Rosen GD,Klein RL,Virella G,Lopes-Virella MF,DCCT\/EDIC Research Group.

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:To test the effect of an automated system providing real-time estimates of HbA(1c), glucose variability, and risk for hypoglycemia. RESEARCH DESIGN AND METHODS:For 1 year, 120 adults with type 1 diabetes (69 female/51 male, age = 39.1 [14.3] years, duration of diabetes 20.3 [12.9] years, HbA(1c) = 8.0 [1.5])...

journal_title：Diabetes care

authors： Kovatchev BP,Mendosa P,Anderson S,Hawley JS,Ritterband LM,Gonder-Frederick L

更新日期：2011-02-01 00:00:00

abstract：:Metformin is and has been considered as first-line therapy for type 2 diabetes for over a quarter of a century. Like other biguanides, metformin can cause a lactic acidosis that is exceptionally rare but fatal. The likelihood of metformin-associated lactic acidosis is substantially higher in patients with kidney impai...

journal_title：Diabetes care

authors： Bakris GL,Molitch ME

更新日期：2016-07-01 00:00:00

abstract：:A preliminary study was performed to estimate the effect of biosynthetic human insulin (BHI) produced by the Eli Lilly Company in comparison with purified pork insulin (PPI) from the same manufacturer. Immunologic studies were done using an intradermal skin test with both insulins and in vitro studies binding with ser...

journal_title：Diabetes care

authors： Federlin K,Laube H,Velcovsky HG

更新日期：1981-03-01 00:00:00

abstract：:OBJECTIVE Using the clamp technique, youths with a clinical diagnosis of type 2 diabetes (CDx-type 2 diabetes) and positive pancreatic autoantibodies (Ab(+)) were shown to have severe impairment in insulin secretion and less insulin resistance than their peers with negative antibodies (Ab(-)). In this study, we invest...

journal_title：Diabetes care

authors： Tfayli H,Bacha F,Gungor N,Arslanian S

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:To assess the long-term cost-effectiveness of aspirin use among adults aged >or=40 years with newly diagnosed type 2 diabetes. RESEARCH DESIGN AND METHODS:We used a validated cost-effectiveness model of type 2 diabetes to assess the lifetime health and cost consequences of use or nonuse of aspirin. The model...

journal_title：Diabetes care

authors： Li R,Zhang P,Barker LE,Hoerger TJ

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:This study estimated the screening prevalence of prediabetes and diabetes using a lower BMI cutoff of 23 kg/m(2) in Asians in the U.S. using the National Health and Nutrition Examination Survey (NHANES) from 2011 to 2012. RESEARCH DESIGN AND METHODS:A cross-sectional analysis was conducted of non-Hispanic As...

journal_title：Diabetes care

authors： Hsia DS,Larrivee S,Cefalu WT,Johnson WD

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:Prevalence and prognostic impact of cardiovascular disease differ between patients with or without diabetes. We aimed to explore differences in the prevalence and prognosis of myocardial ischemia by automated quantification of total perfusion deficit (TPD) among patients with and without diabetes. RESEARCH D...

journal_title：Diabetes care

authors： Han D,Rozanski A,Gransar H,Sharir T,Einstein AJ,Fish MB,Ruddy TD,Kaufmann PA,Sinusas AJ,Miller EJ,Bateman TM,Dorbala S,Di Carli M,Liang JX,Hu LH,Germano G,Dey D,Berman DS,Slomka PJ

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:Given the transient nature of exercise-induced improvements in insulin sensitivity, it has been speculated that daily exercise is preferred to maximize the benefits of exercise for glycemic control. The current study investigates the impact of daily exercise versus exercise performed every other day on glycem...

journal_title：Diabetes care

authors： van Dijk JW,Tummers K,Stehouwer CD,Hartgens F,van Loon LJ

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:To investigate the efficacy and safety of prandial Technosphere inhaled insulin (TI), an inhaled insulin with a distinct time action profile, in insulin-naïve type 2 diabetes (T2D) inadequately controlled on oral antidiabetes agents (OADs). RESEARCH DESIGN AND METHODS:Subjects with T2D with HbA1c levels ≥7.5...

journal_title：Diabetes care

authors： Rosenstock J,Franco D,Korpachev V,Shumel B,Ma Y,Baughman R,Amin N,McGill JB,Affinity 2 Study Group.

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:Alterations of pancreatic β-cell cholesterol content may contribute to β-cell dysfunction. Two important determinants of intracellular cholesterol content are the ATP-binding cassette (ABC) transporters A1 (ABCA1) and -G1 (ABCG1). Whether genetic variation in ABCA1 and ABCG1 predicts risk of type 2 diabetes i...

journal_title：Diabetes care

authors： Schou J,Tybjærg-Hansen A,Møller HJ,Nordestgaard BG,Frikke-Schmidt R

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:To determine whether, reflecting trends in other chronic complications, incident hospitalization for diabetes-related foot ulcer (DFU) has declined over recent decades in type 2 diabetes. RESEARCH DESIGN AND METHODS:Participants with type 2 diabetes from the community-based Fremantle Diabetes Study phases I ...

journal_title：Diabetes care

authors： Hamilton EJ,Davis WA,Siru R,Baba M,Norman PE,Davis TME

更新日期：2021-01-13 00:00:00

abstract：OBJECTIVE:To quantify age-related variability of insulin needs during day and night closed-loop insulin delivery. RESEARCH DESIGN AND METHODS:We retrospectively analyzed data from hybrid closed-loop studies involving young children (1-6 years old, n = 20), children (7-12 years, n = 21), adolescents (13-17 years, n = 1...

journal_title：Diabetes care

authors： Dovc K,Boughton C,Tauschmann M,Thabit H,Bally L,Allen JM,Acerini CL,Arnolds S,de Beaufort C,Bergenstal RM,Campbell F,Criego A,Dunger DB,Elleri D,Evans ML,Fröhlich-Reiterer E,Hofer S,Kapellen T,Leelarathna L,Pieber T

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:To determine whether impairments in neurocognitive functioning are detectable at type 1 diabetes diagnosis and associated with subsequent glycemic control. RESEARCH DESIGN AND METHODS:Children/adolescents (N = 147) aged 5-18 years completed neuropsychological testing during their inpatient hospitalization fo...

journal_title：Diabetes care

authors： Schwartz DD,Axelrad ME,Anderson BJ

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:To determine the characteristics that influence glycemic control among insulin-using adults with type 2 diabetes. RESEARCH DESIGN AND METHODS:We studied all 1,333 eligible members of a large not-for-profit health maintenance organization who responded to a 1997 survey. We tested associations among demographi...

journal_title：Diabetes care

authors： Nichols GA,Hillier TA,Javor K,Brown JB

更新日期：2000-03-01 00:00:00

abstract：OBJECTIVE:To compare the effect of morning and bedtime NPH insulin combined with daytime sulfonylurea on glycemic control in non-insulin-dependent diabetes mellitus (NIDDM) patients no longer responding to treatment with sulfonylureas alone. RESEARCH DESIGN AND METHODS:Twenty-four NIDDM patients who fulfilled these cr...

journal_title：Diabetes care

authors： Groop LC,Widén E,Ekstrand A,Saloranta C,Franssila-Kallunki A,Schalin-Jäntti C,Eriksson JG

更新日期：1992-07-01 00:00:00

abstract：OBJECTIVE:Treatment guidelines for diabetes have become increasingly stringent as most research shows that more aggressive intervention reduces the risks for complications. Community data on the effect of these interventions are lacking. RESEARCH DESIGN AND METHODS:Changes in the pharmacologic treatment of diabetes, b...

journal_title：Diabetes care

authors： Looker HC,Krakoff J,Andre V,Kobus K,Nelson RG,Knowler WC,Hanson RL

更新日期：2010-11-01 00:00:00