Changes in subcutaneous fat cell volume and insulin sensitivity after weight loss.

abstract：:Sixty-two subjects having either insulin-dependent or non-insulin-dependent diabetes completed a randomized, double-blind study comparing effects of aspartame or a placebo on blood glucose control. Twenty-nine subjects consumed 2.7 g aspartame per day for 18 wk, given as aspartame-containing capsules with meals, while...

journal_title：Diabetes care

authors： Nehrling JK,Kobe P,McLane MP,Olson RE,Kamath S,Horwitz DL

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVE:Age at onset of type 1 diabetes influences the risk of microvascular complications. However, the long-term risk of proliferative retinopathy within the wide spectrum of age at onset of type 1 diabetes is less well known. RESEARCH DESIGN AND METHODS:A sample of 1,117 consecutively recruited patients was drawn...

journal_title：Diabetes care

authors： Hietala K,Harjutsalo V,Forsblom C,Summanen P,Groop PH,FinnDiane Study Group.

更新日期：2010-06-01 00:00:00

abstract：:We have developed computer programs in compiled BASIC for the IBM-PC and compatible microcomputers for use by physicians, paramedical personnel, and/or patients to assist with self-monitoring of blood glucose (SMBG) and self-adjustment of insulin dosage. The programs can potentially assist with patient education and m...

journal_title：Diabetes care

authors： Pernick NL,Rodbard D

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVE:To compare lifestyle factors, cardiovascular risk factors, and coronary artery calcium (CAC) and abdominal aortic calcium (AAC) levels in Hispanic and non-Hispanic white (NHW) individuals with type 2 diabetes. RESEARCH DESIGN AND METHODS:We recently demonstrated in a small group of nonreferred, healthy, nond...

journal_title：Diabetes care

authors： Reaven PD,Sacks J,Investigators for the Veterans Affairs Cooperative Study of Glycemic Control and Complications in Diabetes Mellitus Type 2.

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:The use of thiazolidinedione (TZD) derivatives is associated with fluid retention, especially when combined with insulin. Because TZDs improve the metabolic effect of insulin, they may also reverse the blunted vascular response to insulin. We hypothesize that improvement of the action of insulin on vascular t...

journal_title：Diabetes care

authors： Rennings AJ,Smits P,Stewart MW,Tack CJ

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVE:Blood pressure control can reduce the risk of coronary heart disease (CHD) among diabetic patients; however, it is not known whether the lowest risk of CHD is among diabetic patients with the lowest blood pressure level. RESEARCH DESIGN AND METHODS:We performed a prospective cohort study (2000-2009) on diabe...

journal_title：Diabetes care

authors： Zhao W,Katzmarzyk PT,Horswell R,Wang Y,Li W,Johnson J,Heymsfield SB,Cefalu WT,Ryan DH,Hu G

更新日期：2013-10-01 00:00:00

abstract：:Significant data suggest that overt hyperglycemia, either observed with or without a prior diagnosis of diabetes, contributes to an increase in mortality and morbidity in hospitalized patients. In this regard, goal-directed insulin therapy has remained as the standard of care for achieving and maintaining glycemic con...

journal_title：Diabetes care

authors： Schwartz S,DeFronzo RA

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:The current study aimed to determine in the Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications cohort whether or not abnormal levels of markers of inflammation and endothelial dysfunction measured in samples collected at DCCT baseline were able to predict ...

journal_title：Diabetes care

authors： Lopes-Virella MF,Baker NL,Hunt KJ,Cleary PA,Klein R,Virella G,DCCT\/EDIC Research Group.

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:The impact of major affective disorders on the effectiveness of diabetes prevention programs at promoting health behaviors has not been established. We investigated whether depression modifies the effectiveness of two pragmatic diabetes prevention programs at promoting increased physical activity. RESEARCH D...

journal_title：Diabetes care

authors： Yates T,Gray LJ,Henson J,Edwardson CL,Khunti K,Davies MJ

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:To explore patients' and health professionals' experiences of initiating insulin as part of the Treating To Target in Type 2 Diabetes (4-T) randomized controlled trial. RESEARCH DESIGN AND METHODS:Interviews were conducted with 45 trial participants and 21 health professionals and thematically analyzed. RES...

journal_title：Diabetes care

authors： Jenkins N,Hallowell N,Farmer AJ,Holman RR,Lawton J

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:Type 2 diabetes is a heterogeneous disease in which both beta-cell dysfunction and insulin resistance are pathogenetic factors. Disproportionate hyperproinsulinemia (elevated proinsulin/insulin) is another abnormality in type 2 diabetes whose mechanism is unknown. Increased demand due to obesity and/or insuli...

journal_title：Diabetes care

authors： Røder ME,Dinesen B,Hartling SG,Houssa P,Vestergaard H,Sodoyez-Goffaux F,Binder C

更新日期：1999-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the role of metabolic control in the progression of diabetic retinopathy during pregnancy. RESEARCH DESIGN AND METHODS:We conducted a prospective cohort study of 155 diabetic women in the Diabetes in Early Pregnancy Study followed from the periconceptional period to 1 month postpartum. Fundus pho...

journal_title：Diabetes care

authors： Chew EY,Mills JL,Metzger BE,Remaley NA,Jovanovic-Peterson L,Knopp RH,Conley M,Rand L,Simpson JL,Holmes LB

更新日期：1995-05-01 00:00:00

abstract：:The American Diabetes Association (ADA) "Standards of Medical Care in Diabetes" includes ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Co...

journal_title：Diabetes care

authors： American Diabetes Association.

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:To determine whether impairments in neurocognitive functioning are detectable at type 1 diabetes diagnosis and associated with subsequent glycemic control. RESEARCH DESIGN AND METHODS:Children/adolescents (N = 147) aged 5-18 years completed neuropsychological testing during their inpatient hospitalization fo...

journal_title：Diabetes care

authors： Schwartz DD,Axelrad ME,Anderson BJ

更新日期：2014-09-01 00:00:00

abstract：:OBJECTIVE Cross-sectional and longitudinal associations among regimen distress (RD), self-management, and glycemic control were undertaken to explore mechanisms of operation among these variables. RESEARCH DESIGN AND METHODS In a behavioral randomized control trial (RCT) to reduce RD, 392 adults with type 2 diabetes w...

journal_title：Diabetes care

authors： Hessler D,Fisher L,Glasgow RE,Strycker LA,Dickinson LM,Arean PA,Masharani U

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To determine whether the severity of retinopathy is higher in a group of NIDDM patients with sBP greater than or equal to 140 mmHg compared with NIDDM patients with sBP less than 140 mmHg. RESEARCH DESIGN AND METHODS:Ophthalmoscopy and FAG were conducted among a group of NIDDM patients with either a sBP abov...

journal_title：Diabetes care

authors： Cignarelli M,De Cicco ML,Damato A,Paternostro A,Pagliarini S,Santoro S,Cardia L,De Pergola G,Giorgino R

更新日期：1992-08-01 00:00:00

abstract：OBJECTIVE:We aimed at developing and cross-validating a mathematical prediction model for an optimal basal insulin infusion pattern for children with type 1 diabetes on continuous subcutaneous insulin infusion therapy (CSII). RESEARCH DESIGN AND METHODS:We used the German/Austrian DPV-Wiss database for quality control...

journal_title：Diabetes care

authors： Holterhus PM,Bokelmann J,Riepe F,Heidtmann B,Wagner V,Rami-Merhar B,Kapellen T,Raile K,Quester W,Holl RW,German\/Austrian DPV-Initiative and the German Pediatric CSII Working Group.

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:The prevalence of type 2 diabetes is rising rapidly in low-income and middle-income countries (LMICs), but the factors driving this rapid increase are not well understood. Adult height, in particular shorter height, has been suggested to contribute to the pathophysiology and epidemiology of diabetes and may i...

journal_title：Diabetes care

authors： Teufel F,Geldsetzer P,Manne-Goehler J,Karlsson O,Koncz V,Deckert A,Theilmann M,Marcus ME,Ebert C,Seiglie JA,Agoudavi K,Andall-Brereton G,Gathecha G,Gurung MS,Guwatudde D,Houehanou C,Hwalla N,Kagaruki GB,Karki KB,Lab

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:Given the role of gut microbiota in regulating metabolism, probiotics administered during pregnancy might prevent gestational diabetes mellitus (GDM). This question has not previously been studied in high-risk overweight and obese pregnant women. We aimed to determine whether probiotics (Lactobacillus rhamnos...

journal_title：Diabetes care

authors： Callaway LK,McIntyre HD,Barrett HL,Foxcroft K,Tremellen A,Lingwood BE,Tobin JM,Wilkinson S,Kothari A,Morrison M,O'Rourke P,Pelecanos A,Dekker Nitert M

更新日期：2019-03-01 00:00:00

abstract：:To evaluate the development of autonomic neuropathy, 23 patients with a moderate (group A) and 18 patients with a long (group B) duration of diabetes and without symptoms of autonomic neuropathy were re-investigated 6 yr after the initial studies. Autonomic nerve function was evaluated from heart reactions to deep bre...

journal_title：Diabetes care

authors： Sundkvist G,Lilja B

更新日期：1985-03-01 00:00:00

abstract：OBJECTIVE:Sustained excess BMI increases the risk of type 1 diabetes (T1D) in autoantibody-positive relatives without diabetes of patients. We tested whether elevated BMI also accelerates the progression of islet autoimmunity before T1D diagnosis. RESEARCH DESIGN AND METHODS:We studied 706 single autoantibody-positive...

journal_title：Diabetes care

authors： Ferrara-Cook C,Geyer SM,Evans-Molina C,Libman IM,Becker DJ,Gitelman SE,Redondo MJ,Type 1 Diabetes TrialNet Study Group.

更新日期：2020-03-01 00:00:00

abstract：:Urinary albumin excretion rate (radial immunodiffusion), glomerular filtration rate (GFR) (single-shot 51Cr-EDTA technique), and arterial blood pressure (BP) were measured in 12 juvenile-onset, insulin-dependent diabetic patients with persistent proteinuria (greater than 0.5 g/day) due to diabetic nephropathy. Mean ag...

journal_title：Diabetes care

authors： Parving HH,Andersen AR,Smidt UM,Friisberg B,Svendsen PA

更新日期：1981-07-01 00:00:00

abstract：OBJECTIVE:Our objective was to compare the performance of oral glucose tolerance tests (OGTTs) and multivariate models incorporating commonly available clinical variables in their ability to predict future cardiovascular disease (CVD). RESEARCH DESIGN AND METHODS:We randomly selected 2,662 Mexican-Americans and 1,595 ...

journal_title：Diabetes care

authors： Stern MP,Fatehi P,Williams K,Haffner SM

更新日期：2002-10-01 00:00:00

abstract：:A semiclosed loop, bedside insulin infusion system using a simple basal infusion algorithm consisting of a linear transition between two insulin delivery rates as blood glucose (BG) increases has been developed. A theoretical study using computer simulation has now been undertaken to examine the effect of BG sampling ...

journal_title：Diabetes care

authors： Furler SM,Kraegen EW,Smallwood RH,Chisholm DJ

更新日期：1985-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the relationship between renal function, ambulatory blood pressure (AMBP), and glycemic control in microalbuminuric IDDM patients compared with normoalbuminuric patients. RESEARCH DESIGN AND METHODS:Nineteen male patients (age 33 +/- 6 years) with slight microalbuminuria (UAE 20-70 micrograms/min...

journal_title：Diabetes care

authors： Poulsen PL,Juhl B,Ebbehøj E,Klein F,Christiansen C,Mogensen CE

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVE:To assess the relationship between subclinical cardiac dysfunction and aerobic exercise capacity (peak VO2) in adults with type 2 diabetes (T2D), a group at high risk of developing heart failure. RESEARCH DESIGN AND METHODS:Cross-sectional study. We prospectively enrolled a multiethnic cohort of asymptomatic...

journal_title：Diabetes care

authors： Gulsin GS,Henson J,Brady EM,Sargeant JA,Wilmot EG,Athithan L,Htike ZZ,Marsh AM,Biglands JD,Kellman P,Khunti K,Webb D,Davies MJ,Yates T,McCann GP

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:Obesity is associated with alterations in corticolimbic-striatal brain regions involved in food motivation and reward. Stress and the presence of food cues may each motivate eating and engage corticolimibic-striatal neurocircuitry. It is unknown how these factors interact to influence brain responses and whet...

journal_title：Diabetes care

authors： Jastreboff AM,Sinha R,Lacadie C,Small DM,Sherwin RS,Potenza MN

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to determine whether a strategy of aggressive cardiovascular risk management reduced the mortality associated with diabetic foot ulceration. RESEARCH DESIGN AND METHODS:After an initial audit of outcomes demonstrating a high mortality rate in 404 diabetic foot ulcer patients wit...

journal_title：Diabetes care

authors： Young MJ,McCardle JE,Randall LE,Barclay JI

更新日期：2008-11-01 00:00:00

abstract：:To investigate vascular responses in insulin-dependent diabetic patients both with and without retinopathy, we have assessed vasodilation by forearm transcutaneous pO2 measurement after 10 min of ischemia produced by a sphygmomanometer cuff. Diabetic patients with proliferative retinopathy had a delayed vasodilatory r...

journal_title：Diabetes care

authors： Haitas B,Barnes A,Shogry ME,Weindling M,Rolfe P,Turner RC

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:Glycemic control (HbA(1c) [A1C]) is strongly associated with microvascular disease in individuals with diabetes, but its relation to macrovascular disease and atherosclerosis is less clear. This study examines the relationship between A1C, carotid intima-media thickness (IMT), and traditional cardiovascular r...

journal_title：Diabetes care

authors： Selvin E,Coresh J,Golden SH,Boland LL,Brancati FL,Steffes MW,Atherosclerosis risk in communities study.

更新日期：2005-08-01 00:00:00