Optic neuropathy in children with Lyme disease.

Abstract:

:Involvement of the optic nerve, either because of inflammation or increased intracranial pressure, is a rare manifestation of Lyme disease. Of the 4 children reported here with optic nerve abnormalities, 2 had decreased vision months after disease onset attributable to optic neuritis, and 1 had headache and diplopia early in the infection because of increased intracranial pressure associated with Lyme meningitis. In these 3 children, optic nerve involvement responded well to intravenous ceftriaxone therapy. The fourth child had headache and visual loss attributable to increased intracranial pressure and perhaps also to optic neuritis. Despite treatment with ceftriaxone and steroids, he had persistent increased intracranial pressure leading to permanent bilateral blindness. Clinicians should be aware that neuro-ophthalmologic involvement of Lyme disease may have significant consequences. If increased intracranial pressure persists despite antibiotic therapy, measures must be taken quickly to reduce the pressure.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Rothermel H,Hedges TR 3rd,Steere AC

doi

10.1542/peds.108.2.477

subject

Has Abstract

pub_date

2001-08-01 00:00:00

pages

477-81

issue

2

eissn

0031-4005

issn

1098-4275

journal_volume

108

pub_type

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