Abstract:
:Patients with phagocyte defects frequently develop bacterial or fungal pneumonias, but they are not considered to be at increased risk for viral infections. We describe 3 patients with known phagocyte immunodeficiencies who developed lower respiratory tract infections (LRTI) caused by respiratory syncytial virus (RSV). All 3 patients had dense pneumonias as indicated by computed tomography scan of the lungs and RSV was recovered. We conclude that RSV can present as a dense pneumonia in patients with phagocyte defects. Along with common pathogens causing LRTI, RSV should be considered in the differential diagnosis. Viral cultures as well as rapid antigen detection assays for respiratory viruses should be included in the evaluation of LRTI in patients with phagocyte defects. respiratory syncytial virus, phagocyte, immunodeficiency, pneumonia.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Uzel G,Premkumar A,Malech HL,Holland SMdoi
10.1542/peds.106.4.835subject
Has Abstractpub_date
2000-10-01 00:00:00pages
835-7issue
4eissn
0031-4005issn
1098-4275journal_volume
106pub_type
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