Superior vena cava syndrome in childhood: report of ten cases and review of the literature.

Abstract:

:Experience with ten children with superior vena cava obstruction is reported. Five patients had non-Hodgkin's lymphoma, two had Hodgkin's disease, two had benign lesions, and one patient was suspected on clinical and radiologic basis to have a lymphoma. The clinical situation at presentation was often critical and required rapid treatment. Radiotherapy and/or chemotherapy were used initially as lymphoma was the most frequent cause of obstruction. Urgent thoracotomy was resorted to when treatment failed. Survival with no evidence of disease for more than 5 years was observed in three children: one had a cystic lymphangioma, another had a mediastinal abscess, and the third had a Hodgkin's lymphoma. Review of the literature from 1951 to 1976 revealed that only 24/150 children reported with superior vena cava obstruction syndrome had mediastinal tumors; the remainder developed the obstruction after surgical procedures on the heart or vena cava.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Issa PY,Brihi ER,Janin Y,Slim MS

subject

Has Abstract

pub_date

1983-03-01 00:00:00

pages

337-41

issue

3

eissn

0031-4005

issn

1098-4275

journal_volume

71

pub_type

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