A perimortem protocol for suspected genetic disease.

Abstract:

:A considerable portion of pediatric deaths represent disease with risk of recurrence in subsequent family members. Procedures to obtain samples of body fluids and tissues suitable for diagnosis of mendelian and chromosomal disorders are described. These procedures, the "perimortem protocol," are used in studying children who died of suspected but undiagnosed genetic disease.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Kronick JB,Scriver CR,Goodyer PR,Kaplan PB

subject

Has Abstract

pub_date

1983-06-01 00:00:00

pages

960-3

issue

6

eissn

0031-4005

issn

1098-4275

journal_volume

71

pub_type

杂志文章
  • Three-year follow-up of vaccine response in extremely preterm infants.

    abstract:OBJECTIVE:To assess whether the adequate antibody response observed in former extremely premature infants after the primary series of immunizations is sustained after the first booster vaccines. SUBJECTS AND METHODS:Sixteen former extremely premature (<29 weeks, <1000 g at birth) and 17 former full-term (>37 weeks) in...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.101.4.597

    authors: Khalak R,Pichichero ME,D'Angio CT

    更新日期:1998-04-01 00:00:00

  • A 2017 US Reference for Singleton Birth Weight Percentiles Using Obstetric Estimates of Gestation.

    abstract:OBJECTIVE:To provide an updated birth weight-for-gestational age (BW-for-GA) reference in the United States by using the most recent, nationally representative birth data with obstetric estimates of gestational age (GA). METHODS:We abstracted 3 285 552 singleton births between 22 and 42 weeks' gestation with nonmissin...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2019-0076

    authors: Aris IM,Kleinman KP,Belfort MB,Kaimal A,Oken E

    更新日期:2019-07-01 00:00:00

  • Comorbidities and Complications of Spinal Fusion for Scoliosis.

    abstract:BACKGROUND AND OBJECTIVES:General pediatricians and hospitalists are increasingly summoned to optimize the comorbid conditions of children with medical complexity (CMC) undergoing major surgery. We assessed the relationship between specific chronic conditions of CMC and hospital resource use with spinal fusion for scol...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.2016-2574

    authors: Berry JG,Glotzbecker M,Rodean J,Leahy I,Hall M,Ferrari L

    更新日期:2017-03-01 00:00:00

  • Wide variation in reference values for aluminum levels in children.

    abstract:BACKGROUND:Some parents are requesting aluminum testing in their children with developmental issues. Although aluminum can be measured in plasma, serum, or urine, there is scant scientific information about normal ranges. We sought to determine the basis for laboratory reference ranges and whether these ranges are appl...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2010-3481

    authors: Zeager M,Woolf AD,Goldman RH

    更新日期:2012-01-01 00:00:00

  • Insulin receptors in cystic fibrosis: increased receptor number and altered affinity.

    abstract::Patients with cystic fibrosis are known to have pancreatic disorganization with associated pancreatic exocrine insufficiency. Endocrine hormonal secretion is also affected but diminution in insulin secretion is rarely accompanied by overt diabetes. We studied seven patients with cystic fibrosis to determine their carb...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Lippe BM,Kaplan SA,Neufeld ND,Smith A,Scott M

    更新日期:1980-05-01 00:00:00

  • Validity of mass blood pressure screening in children.

    abstract::The validity of a mass blood pressure screening program carried out on Dallas high school students who were followed for at least 3 years is reported. Blood pressure results on initial screening in the tenth grade were related to outcome blood pressure status. The frequency of initial blood pressure elevation (systoli...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Fixler DE,Laird WP

    更新日期:1983-10-01 00:00:00

  • Adverse events after the use of benznidazole in infants and children with Chagas disease.

    abstract:BACKGROUND:Chagas disease is caused by infection with Trypanosoma cruzi. In adults, treatment with benznidazole is associated with a high incidence of adverse drug reactions (ADRs). However, in infants and children, treatment with benznidazole seems associated with a lower incidence and decreased severity of ADRs, but ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2010-1172

    authors: Altcheh J,Moscatelli G,Moroni S,Garcia-Bournissen F,Freilij H

    更新日期:2011-01-01 00:00:00

  • Duration of poverty and child health in the Quebec Longitudinal Study of Child Development: longitudinal analysis of a birth cohort.

    abstract:OBJECTIVES:The objective of this study was to examine the relationship between duration of poverty and the health of preschool children in the Quebec Longitudinal Study of Child Development birth cohort. METHODS:Data from the Quebec Longitudinal Study of Child Development for 1950 children who were followed annually u...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2006-1750

    authors: Séguin L,Nikiéma B,Gauvin L,Zunzunegui MV,Xu Q

    更新日期:2007-05-01 00:00:00

  • Electronic prescribing in pediatrics: toward safer and more effective medication management.

    abstract::This policy statement identifies the potential value of electronic prescribing (e-prescribing) systems in improving quality and reducing harm in pediatric health care. On the basis of limited but positive pediatric data and on the basis of federal statutes that provide incentives for the use of e-prescribing systems, ...

    journal_title:Pediatrics

    pub_type: 杂志文章,实务指引

    doi:10.1542/peds.2013-0192

    authors: American Academy of Pediatrics Council on Clinical Information Technology Executive Committee, 2011–2012.

    更新日期:2013-04-01 00:00:00

  • Weight teasing and disordered eating behaviors in adolescents: longitudinal findings from Project EAT (Eating Among Teens).

    abstract:OBJECTIVE:To assess whether weight-related teasing predicts the development of binge eating, unhealthy weight control behaviors, and frequent dieting among male and female adolescents. METHODS:A prospective study was conducted with an ethnically and socioeconomically diverse sample of 2516 adolescents who completed su...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2005-1242

    authors: Haines J,Neumark-Sztainer D,Eisenberg ME,Hannan PJ

    更新日期:2006-02-01 00:00:00

  • Using a preprinted order sheet to reduce prescription errors in a pediatric emergency department: a randomized, controlled trial.

    abstract:OBJECTIVE:Medication errors are common among pediatric patients and in emergency departments (EDs). Such errors may lead to prolonged hospitalization, unnecessary diagnostic tests and treatments, and death. The objective of this study was to determine whether the use of a structured order sheet reduces the incidence of...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2004-2016

    authors: Kozer E,Scolnik D,MacPherson A,Rauchwerger D,Koren G

    更新日期:2005-12-01 00:00:00

  • Variability in head circumference growth rate during the first 2 years of life.

    abstract::The head circumference (HC) curves were plotted for a group of 415 healthy full-term babies over the first 2 years of life. Two hundred ten (51%) of the cohort demonstrated HC variability, defined as an HC acceleration or deceleration of at least 1 centile curve for at least 2 months. Of these, the deceleration patter...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Jaffe M,Tal Y,Hadad B,Tirosh E,Tamir A

    更新日期:1992-08-01 00:00:00

  • No change in the incidence of ampicillin-resistant, neonatal, early-onset sepsis over 18 years.

    abstract:OBJECTIVE:The objective of this study was to assess the effect of maternal antibiotic exposure on neonatal early-onset sepsis (EOS) rates over an 18-year period. METHODS:A review was performed of infant and maternal records for all culture- proven cases of EOS in infants delivered at the Brigham and Women's Hospital (...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2009-1573

    authors: Puopolo KM,Eichenwald EC

    更新日期:2010-05-01 00:00:00

  • Booster seat laws and fatalities in children 4 to 7 years of age.

    abstract:OBJECTIVE:To determine whether state booster seat laws were associated with decreased fatality rates in children 4 to 7 years of age in the United States. METHODS:Retrospective, longitudinal analysis of all motor vehicle occupant crashes involving children 4 to 7 years of age identified in the Fatality Analysis Report...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2012-1058

    authors: Mannix R,Fleegler E,Meehan WP 3rd,Schutzman SA,Hennelly K,Nigrovic L,Lee LK

    更新日期:2012-12-01 00:00:00

  • One-Year Language Outcomes in Toddlers With Language Delays: An RCT Follow-up.

    abstract:OBJECTIVES:The current study is a 1-year follow-up analysis of data from a randomized controlled trial of Enhanced Milieu Teaching (EMT) for toddlers with language delays. Outcomes and predictors of child language and parent intervention implementation were examined 6 and 12 months after the end of the intervention. M...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2016-3646

    authors: Hampton LH,Kaiser AP,Roberts MY

    更新日期:2017-11-01 00:00:00

  • Prolonged episodes of hypoxemia in preterm infants undetectable by cardiorespiratory monitors.

    abstract:OBJECTIVE:To determine whether episodes of prolonged hypoxemia occur without prolonged apneic pauses (> or = 20 seconds) and without bradycardia (pulse rate, < or = 100 beats per minute) in apparently well preterm infants. METHODS:Long-term recordings of arterial oxygen saturation as measured by pulse oximetry (SpO2),...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Poets CF,Stebbens VA,Richard D,Southall DP

    更新日期:1995-06-01 00:00:00

  • Fatal and nonfatal farm injuries to children and adolescents in the United States.

    abstract::Agriculture is the second most dangerous occupation in the United States, and unlike other occupations, children make up a significant portion of the work force. This study presents national data on the morbidity and mortality due to farm injuries to children and adolescents less than or equal to 19 years of age. Data...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Rivara FP

    更新日期:1985-10-01 00:00:00

  • Media literacy education for elementary school substance use prevention: study of media detective.

    abstract:OBJECTIVES:Media Detective is a 10-lesson elementary school substance use prevention program developed on the basis of the message interpretation processing model designed to increase children's critical thinking skills about media messages and reduce intent to use tobacco and alcohol products. The purpose of this stud...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1542/peds.2010-0068

    authors: Kupersmidt JB,Scull TM,Austin EW

    更新日期:2010-09-01 00:00:00

  • Reevaluation of outpatients with Streptococcus pneumoniae bacteremia.

    abstract:BACKGROUND:The reevaluation process for outpatients recalled for Streptococcus pneumoniae bacteremia has not been standardized. Children who return ill or with new serious focal infections require admission and parenteral antibiotic therapy. Limited data exist to guide the follow-up management of those patients identif...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.105.3.502

    authors: Bachur R,Harper MB

    更新日期:2000-03-01 00:00:00

  • Determination of timing of brain injury in preterm infants with periventricular leukomalacia with serial neonatal electroencephalography.

    abstract:OBJECTIVE:The aim of this study was to determine the timing of brain injury in infants with periventricular leukomalacia (PVL) with serial electroencephalography (EEG) recordings during the neonatal period. PATIENTS AND METHODS:We evaluated 172 preterm infants having a gestational age <33 weeks and weighing <2000 g. I...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.104.5.1077

    authors: Hayakawa F,Okumura A,Kato T,Kuno K,Watanabe K

    更新日期:1999-11-01 00:00:00

  • Health literacy and child health outcomes: a systematic review of the literature.

    abstract:OBJECTIVES:To review the relationship between parent and child literacy and child health outcomes and interventions designed to improve child health outcomes for children or parents with low literacy skills. METHODS:We searched Medline and the Cumulative Index to Nursing and Allied Health Literature (CINAHL) for artic...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2009-1162B

    authors: DeWalt DA,Hink A

    更新日期:2009-11-01 00:00:00

  • School food environments and policies in US public schools.

    abstract:OBJECTIVE:The purpose of this study was to describe school food environments and policies in US public schools and how they vary according to school characteristics. METHODS:We analyzed cross-sectional data from the third School Nutrition and Dietary Assessment study by using a nationally representative sample of 395 ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2007-2814

    authors: Finkelstein DM,Hill EL,Whitaker RC

    更新日期:2008-07-01 00:00:00

  • Osteomyelitis and sepsis: severe complications of fetal monitoring.

    abstract::Sophisticated modern methods of fetal monitoring during labor have improved the prognosis for high-risk infants, but the possible adverse side effects have not yet been fully documented. One infant with osteomyelitis and one with streptococcal sepsis are reported. In the future, greater attention should be paid to suc...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Overturf GD,Balfour G

    更新日期:1975-02-01 00:00:00

  • Sweet syndrome associated with G-CSF treatment in a child with glycogen storage disease type Ib.

    abstract::Acute febrile neutrophilic dermatosis (Sweet syndrome) is rare in children and is regularly associated with underlying malignancies or inflammtory diseases. A 5-year-old girl with glycogen storage disease type Ib, neutropenia, and recurrent infections developed characteristic skin eruption of Sweet syndrome after 2 ye...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Garty BZ,Levy I,Nitzan M,Barak Y

    更新日期:1996-03-01 00:00:00

  • Elevated lead levels in children with nonorganic failure to thrive.

    abstract::Every child with failure to thrive has at least one organic medical disease: malnutrition. It is well documented that lead and other heavy metals are absorbed more readily in the presence of both malnutrition and iron deficiency anemia. Malnutrition and lead exposure tend to be found in the same population groups. Fur...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Bithoney WG

    更新日期:1986-11-01 00:00:00

  • Adenovirus meningoencephalitis.

    abstract::Central nervous system manifestations in association with adenovirus infections have rarely been documented. In this report, four children, ages 4, 5, 6, and 10 years, with adenoviral meningoencephalitis are described. Adenoviruses were recovered from CSF specimens in all four patients. ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Kelsey DS

    更新日期:1978-02-01 00:00:00

  • Annual summary of vital statistics--1982.

    abstract::Data for this article, as in previous reports, are drawn principally from the Monthly Vital Statistics Report, published by the National Center for Health Statistics. The international data come from the Demographic Yearbook and the quarterly Population and Vital Statistics Report, both published by the Statistical Of...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Wegman ME

    更新日期:1983-12-01 00:00:00

  • Dopamine versus epinephrine for cardiovascular support in low birth weight infants: analysis of systemic effects and neonatal clinical outcomes.

    abstract:BACKGROUND:Early postnatal adaptation to transitional circulation in low birth weight infants frequently is associated with low blood pressure and decreased blood flow to organs. Catecholamines have been used widely as treatment, despite remarkably little empirical evidence on the effects of vasopressor/inotropic suppo...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2005-2108

    authors: Valverde E,Pellicer A,Madero R,Elorza D,Quero J,Cabañas F

    更新日期:2006-06-01 00:00:00

  • Asthma morbidity after the short-term use of ibuprofen in children.

    abstract:OBJECTIVE:To test the hypothesis that short-term use of ibuprofen increases asthma morbidity in children. METHODS:A randomized, double-blind, acetaminophen-controlled clinical trial was conducted. Children who had asthma and a febrile illness were randomly assigned to receive either acetaminophen suspension or ibuprof...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1542/peds.109.2.e20

    authors: Lesko SM,Louik C,Vezina RM,Mitchell AA

    更新日期:2002-02-01 00:00:00

  • Predictors of Medication Continuity in Children With ADHD.

    abstract:OBJECTIVES:To identify predictors of attention-deficit/hyperactivity disorder (ADHD) medication continuity, hypothesizing greater continuity among children with (1) greater child acceptance of treatment, (2) parent belief in longer time course for ADHD, (3) positive differential between parent-perceived need for and co...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2017-2580

    authors: Brinkman WB,Sucharew H,Majcher JH,Epstein JN

    更新日期:2018-06-01 00:00:00