Abstract:
:The efficacy, adverse reactions, and long-term effects of intestinal lavage treatment with a balanced electrolyte solution (Golytely) was evaluated in patients with cystic fibrosis and distal intestinal obstruction syndrome. Twenty-two patients with cystic fibrosis (mean age 21.8 years, range 14 to 34 years, 15 boys or men) who sought medical attention because of abdominal pain and a mass in the right iliac fossa received Golytely, 5.6 +/- 1.9 L (mean +/- 1 SD), either orally (n = 14) or via nasogastric tube (n = 8) during 5.6 +/- 2.4 hours. No serious side effects occurred. Serum electrolyte values remained within normal limits. Body weight did not change significantly. Minor adverse reactions included bloating (n = 12), nausea (n = 8), vomiting (n = 1), and chills (n = 3). All but one patient reported impressive relief of symptoms and remained pain free for an average of 3 months (range 1 to 19 months). Symptoms of abdominal pain and radiologic signs of fecal impaction assessed before and after lavage both decreased significantly (P less than .0001). During follow-up (mean 15.2 months, range 4 to 26 months), 11 patients required a total of 38 (range one to nine) additional doses of Golytely. Seven patients drank the solution at home (21 treatments); only two patients chose a nasogastric tube. In ten patients with symptoms of recurrent distal intestinal obstruction syndrome prior to institution of therapy, duration of hospitalization was significantly reduced by this treatment (5.1 +/- 7.6 v 2.3 +/- 6.3 hospital days per annum, P less than .02).(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Pediatricsjournal_title
Pediatricsauthors
Koletzko S,Stringer DA,Cleghorn GJ,Durie PRsubject
Has Abstractpub_date
1989-05-01 00:00:00pages
727-33issue
5eissn
0031-4005issn
1098-4275journal_volume
83pub_type
杂志文章相关文献
PEDIATRICS文献大全abstract:OBJECTIVE:The optimal treatment of neonatal hyperglycemia is unclear. The aim of this trial was to determine whether tight glycemic control with insulin improves growth in hyperglycemic preterm infants, without increasing the incidence of hypoglycemia. METHODS:Randomized, controlled, nonblinded trial of 88 infants bor...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2011-2470
更新日期:2012-04-01 00:00:00
abstract::Because of a persistently elevated caffeine half-life observed in a breast-fed infant during caffeine maintenance therapy, we conducted this prospective longitudinal study in two groups of infants (five exclusively breast-fed and 12 formula-fed). After 46 weeks' postconceptional age, all five breast-fed infants had a ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1987-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:An increase in the incidence of systemic candidiasis (SC) followed a change in skin care for extremely low birth weight (ELBW) infants in our neonatal intensive care unit (NICU). We sought to determine whether the use of topical petrolatum ointment (TPO) for skin care of ELBW infants was associ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.105.5.1041
更新日期:2000-05-01 00:00:00
abstract:OBJECTIVE:The goal of this study was to determine if congenital human herpesvirus-6 (HHV-6) infection influences early neurodevelopment. METHODS:We enrolled 57 newborns with HHV-6 congenital infection and 242 control newborns without congenital infection into a prospective, double-blind study with 4 visits between 4 a...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2014-0886
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to compare the frequency of risk behaviors and to measure the extent of co-occurrence of these behaviors in chronically ill and healthy adolescents. METHODS:Data were drawn from the 2002 Swiss Multicenter Adolescent Survey on Health database, a nationally representative survey...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2008-1479
更新日期:2008-11-01 00:00:00
abstract:OBJECTIVE:For preventing nosocomial influenza infections and to facilitate prompt antiviral therapy, an accessible, rapid diagnostic method for influenzavirus is needed. We evaluated the performance of a lateral-flow immunoassay (QuickVue Influenza Test) completed at the bedside of hospitalized children during the infl...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.110.1.83
更新日期:2002-07-01 00:00:00
abstract:OBJECTIVES:Early nasal continuous positive airway pressure (ENCPAP) has recently emerged in neonatal units as an acceptable alternative to routine intubation and mandatory ventilation. The risks and benefits of ENCPAP have yet to be established. In this study, we aimed to examine variables that influenced the decision ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2004-2493
更新日期:2005-06-01 00:00:00
abstract:CONTEXT:The prevalence of neural tube defects is reduced in populations of women who receive folic acid supplementation. Since 1998, grain products in the United States have been fortified with folic acid. Fortification may have additional benefits by reducing the national prevalence of newborn hospitalizations for oth...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2005-2784
更新日期:2006-09-01 00:00:00
abstract::Three infants with infant botulism are presented to illustrate how atypical, early, and severe features may obscure or delay diagnosis. Two boys aged 6 weeks and 20 days, respectively, presented with rapid deterioration after brief periods of poor feeding, one with an apparent life-threatening event at home and the ot...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2005-0297
更新日期:2005-09-01 00:00:00
abstract:OBJECTIVE:To build predictive models of severe adverse outcome at various times in the course of neonatal bacterial meningitis. STUDY DESIGN:Retrospective cohort study with follow-up to a minimum age of 1 year of term and near-term infants, admitted between 1979 and 1998 to a regional tertiary care center. Predictors ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.106.3.477
更新日期:2000-09-01 00:00:00
abstract::Suspension and expulsion from school are used to punish students, alert parents, and protect other students and school staff. Unintended consequences of these practices require more attention from health care professionals. Suspension and expulsion may exacerbate academic deterioration, and when students are provided ...
journal_title:Pediatrics
pub_type: 指南,杂志文章,实务指引
doi:10.1542/peds.112.5.1206
更新日期:2003-11-01 00:00:00
abstract::Ultrasound has become a useful tool in the workup of pediatric patients because of the highly convenient, cost-effective, and safe nature of the examination. With rapid advancements in anatomic and functional ultrasound techniques over the recent years, the diagnostic and interventional utility of ultrasound has risen...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2018-2609
更新日期:2019-03-01 00:00:00
abstract::Premature male infants have a higher incidence of respiratory distress syndrome (RDS) than female infants (male/female = 1.7:1.) With the demonstration that antenatal use of betamethasone significantly reduces the incidence of RDS, a proportional reduction or possibly a complete elimination of the discrepancy between ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1981-05-01 00:00:00
abstract:OBJECTIVES:To determine hepatitis B virus (HBV) carrier and infection rates and HBV epidemiology in Honolulu students. DESIGN:Cross-sectional survey. SETTING:Honolulu public elementary, intermediate, and high schools. PATIENTS:A volunteer sample of 4936 students from 43 Honolulu schools. MAIN OUTCOME MEASURES:HBV c...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1993-10-01 00:00:00
abstract::Motor vehicle-related trauma is the leading cause of death in children in the United States. All states have pediatric restraint requirements for passenger vehicles to help prevent these deaths and injuries. Only a few states, however, possess safety laws or restrictions for passengers who ride in the back of pickup t...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1990-11-01 00:00:00
abstract::As part of a multicenter collaborative study, M-mode echocardiograms were obtained shortly after birth on 3,559 premature infants with birth weight less than or equal to 1,750 g. Of these infants, 1,496 did not develop a cardiac murmur or other signs of a "hemodynamically significant" patent ductus arteriosus (PDA). E...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1983-12-01 00:00:00
abstract:OBJECTIVE:Health-e-Access, a telemedicine service providing care for acute illnesses in children, has delivered >6500 telemedicine visits from 10 primary care practices in Rochester, New York, by using telemedicine access at 22 child care and school sites. The goal was to assess the hypotheses that children served by H...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2008-2698
更新日期:2009-06-01 00:00:00
abstract::To determine the long-term effects of therapeutic pulmonary irradiation and treatment with actinomycin D during a period of lung growth, 12 patients treated for Wilms' tumor metastatic to the lung and 8 patients treated for Wilms' tumor with no evidence of pulmonary metastases were studied 7 to 14 years after their in...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1975-04-01 00:00:00
abstract::Cariogenicity of seven commonly prescribed liquid medications was studied. Sucrose content of the medications ranged from 0 to 70 gm/100 ml. Initial pH and buffering capacity were measured and found to vary widely among the medications. Intraoral microbial plaque pH changes were determined at intervals for 30 minutes ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1981-09-01 00:00:00
abstract::A review of hospital admissions of patients with status asthmaticus at the Childrens Hospital of Los Angeles showed a marked increase in admissions in recent years. Asthma mortality did not increase. Patients tended to be young, boys, and black as compared with patients admitted to a general hospital. Interviews with ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1989-07-01 00:00:00
abstract:OBJECTIVE:To determine if there is a relationship between diabetes outcome as measured by HbA1C and the number of multidisciplinary clinic visits per year in children and youth with diabetes. RESEARCH DESIGN AND METHODS:The number of clinic visits per year, the mean HbA1C (by DCA 2000, Miles, Tarrytown, NY), type of i...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.103.5.948
更新日期:1999-05-01 00:00:00
abstract:OBJECTIVE:To assess 1) knowledge of neural tube defect (NTD) prevention by folic acid, 2) frequency of intake of multivitamins and folate- and folic acid-fortified food, and 3) factors associated with knowledge and prevention practices among sexually active minority adolescent and young adult women. METHODS:Young mino...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.112.3.536
更新日期:2003-09-01 00:00:00
abstract::Most family members who are evaluated as kidney donors for children have high reactivity in a mixed lymphocyte culture test and are thus excluded from donation. Fifty children, most of whom had highly reactive mixed lymphocyte cultures with their donors, were challenged with three blood transfusions from their donors ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1985-09-01 00:00:00
abstract:OBJECTIVE:Because of case reports describing hypoxemia on withdrawal of inhaled nitric oxide (I-NO), we prospectively examined this safety issue in newborns with persistent pulmonary hypertension who were classified as treatment successes or failures during a course of I-NO therapy. METHODS:Randomized, placebo-control...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1542/peds.104.2.231
更新日期:1999-08-01 00:00:00
abstract::For centuries, many physicians and parents assumed that it was ethically justifiable to lie to a dying child. The reasoning was clear. Because the lie would likely eliminate or prevent a concrete harm (the child's fear), and the lie is about a harm that is unavoidable anyway, a lie appeared to be the morally desirable...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2014-1394D
更新日期:2014-10-01 00:00:00
abstract::Despite the absence of a clear-cut rationale for their use, corticosteroids are widely employed in the treatment of dengue shock syndrome. Previous comparative therapeutic trials have yielded contradictory results. Resolution of this therapeutic controversy has been attempted with a double-blind evaluation of the clin...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1982-01-01 00:00:00
abstract:BACKGROUND:Adolescent men who have sex with men (AMSM) have a high rate of HIV diagnoses. An estimated 14.5% of HIV infections in the United States are undiagnosed; but among 13- to 24-year-olds, the rate is 51.4%. We describe HIV testing rates and identifies salient individual, family, school, and health care influenc...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2019-2322
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Transitions from the hospital to home can be difficult for patients and families. Family-informed characterization of this vulnerable period may facilitate the identification of interventions to improve transitions home. Our objective was to develop a comprehensive understanding of hospital-to-...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2015-2098
更新日期:2015-12-01 00:00:00
abstract::A number of pediatric collaborative improvement networks have demonstrated improved care and outcomes for children. Regionally, Cincinnati Children's Hospital Medical Center Physician Hospital Organization has sustained key asthma processes, substantially increased the percentage of their asthma population receiving "...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2012-3786F
更新日期:2013-06-01 00:00:00
abstract:CONTEXT:In the last few years, there has been an increasing amount of research showing the concurrent and long-term consequences of bullying and being bullied by peers. OBJECTIVE. We performed a meta-analysis to quantify the association between involvement in bullying and psychosomatic complaints in the school-aged pop...
journal_title:Pediatrics
pub_type: 杂志文章,meta分析
doi:10.1542/peds.2008-1215
更新日期:2009-03-01 00:00:00