Abstract:
OBJECTIVES:To determine hepatitis B virus (HBV) carrier and infection rates and HBV epidemiology in Honolulu students. DESIGN:Cross-sectional survey. SETTING:Honolulu public elementary, intermediate, and high schools. PATIENTS:A volunteer sample of 4936 students from 43 Honolulu schools. MAIN OUTCOME MEASURES:HBV carrier rate (presence of hepatitis B surface antigen) and infection rate (presence of either hepatitis B surface antigen, antibody to hepatitis B surface antigen, antibody to hepatitis B core antigen, or any combinations of these) by school grade, ethnicity, and place of birth. RESULTS:Eighty-three (1.68%) students were identified as HBV carriers, and a total of 353 (7.15%) students had serologic evidence of infection. Infection rates increased from elementary school age to high school age, more so in Asian/Pacific Island-born students. The prevalence of infection was higher in Asian/Pacific Island-born students than in those born in the United States. The majority of infected Hawaiian-born students were first-generation Asian/Pacific Island Americans. CONCLUSIONS:Horizontal transmission of HBV occurs in Honolulu school-age children. HBV immunization of all infants in Hawaii, not just those born to carrier mothers, is necessary to reduce HBV transmission in Hawaii.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Pon EW,Ren H,Margolis H,Zhao Z,Schatz GC,Diwan Asubject
Has Abstractpub_date
1993-10-01 00:00:00pages
574-8issue
4eissn
0031-4005issn
1098-4275journal_volume
92pub_type
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