Clinicopathologic spectrum of resected extraductal mass-forming intrahepatic cholangiocarcinoma.

abstract：BACKGROUND:Screening is effective in reducing the incidence and mortality of colorectal cancer. Rates of colorectal cancer test use continue to be low. METHODS:The authors analyzed data from the National Health Interview Survey concerning the use of the home-administered fecal occult blood test (FOBT) and sigmoidoscop...

journal_title：Cancer

authors： Seeff LC,Nadel MR,Klabunde CN,Thompson T,Shapiro JA,Vernon SW,Coates RJ

更新日期：2004-05-15 00:00:00

abstract：BACKGROUND:Aggressive treatment of early stage prostate carcinoma (PC) is limited primarily to two modalities: radical prostatectomy (RP) and external beam radiation therapy (RT). The authors conducted a population-based study of Detroit area men with localized PC to determine the outcome of bowel, urinary, and sexual ...

journal_title：Cancer

authors： Schwartz K,Bunner S,Bearer R,Severson RK

更新日期：2002-07-01 00:00:00

abstract：:Based on experience with three cases of endobronchial non-Hodgkin's lymphoma and a review of cases previously reported, two patterns of lymphomatous involvement of airways are described. The Type 1 pattern is characterized by diffuse submucosal infiltrates occurring in the presence of intra- and extrathoracic lymphoma...

journal_title：Cancer

authors： Rose RM,Grigas D,Strattemeir E,Harris NL,Linggood RM

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:Although systemic therapy for metastatic breast cancer (MBC) continues to evolve, there are scant data to guide physicians and patients when symptoms develop. In this article, the authors report the frequency and durability of palliative procedures performed in the setting of MBC. METHODS:From July 2002 to ...

journal_title：Cancer

authors： Morrogh M,Miner TJ,Park A,Jenckes A,Gonen M,Seidman A,Morrow M,Jaques DP,King TA

更新日期：2010-07-15 00:00:00

abstract：BACKGROUND:A phase 2 trial was carried out to assess the antineoplastic activity of 2 courses of cyclophosphamide-etoposide in relapsed osteosarcoma patients. METHODS:Twenty-six relapsed osteosarcoma patients with a median age of 18.5 years (8.3-47.1) were enrolled. Seven patients were in first relapse (27%), 11 in se...

journal_title：Cancer

authors： Berger M,Grignani G,Ferrari S,Biasin E,Brach del Prever A,Aliberti S,Saglio F,Aglietta M,Fagioli F

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Bortezomib is active in heavily pretreated multiple myeloma patients; the dose-limiting toxicity is peripheral neuropathy (PN). METHODS:The authors retrospectively reviewed the incidence, severity, and risk factors for PN in 78 patients who received bortezomib. The median age was 57 years (range, 33-80 year...

journal_title：Cancer

authors： Badros A,Goloubeva O,Dalal JS,Can I,Thompson J,Rapoport AP,Heyman M,Akpek G,Fenton RG

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:The effects of relaxin (RLX) on the human breast adenocarcinoma cell line MCF-7 have been evaluated. METHODS:The cells were maintained in culture with Dulbecco's modified Eagle's medium with 1% and 10% fetal calf serum. Highly purified porcine RLX was added at concentrations ranging between 10(-11) and 10(-...

journal_title：Cancer

authors： Bigazzi M,Brandi ML,Bani G,Sacchi TB

更新日期：1992-08-01 00:00:00

abstract：:Numerous examples exist of prognostic factors that have been conclusively established and that can segregate the target patient population into subgroups with vastly different outcomes. At the same time, we can expect, in the majority of trials being conducted, that if a new treatment turns out to be successful, it ge...

journal_title：Cancer

authors： Sather HN

更新日期：1986-07-15 00:00:00

abstract：BACKGROUND:The expression of a distinct alpha-3/4-monofucosylated polylactosaminoglycan epitope, which is detected by monoclonal antibody FW6, was investigated by comparative immunohistochemical analysis of colorectal tissue specimens exhibiting different grades of premalignant and malignant transformation. The presenc...

journal_title：Cancer

authors： Baldus SE,Vierbuchen M,Hanisch FG,Schwonzen M,Fischer R

更新日期：1995-09-15 00:00:00

abstract：BACKGROUND:Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) biopsy allows the detailed imaging and FNA not only of both intramural and extramural structures and lesions of the gastrointestinal (GI) tract but also of various intraabdominal organs. Thus, EUS-FNA biopsy offers a novel opportunity to evaluate ...

journal_title：Cancer

authors： Jhala NC,Jhala D,Eloubeidi MA,Chhieng DC,Crowe DR,Roberson J,Eltoum I

更新日期：2004-10-25 00:00:00

abstract：:The radionuclide, gallium-67, accumulates in a wide variety of neoplastic and inflammatory lesions. Diffuse bilateral lung localization of 67Ga occurred in two cases of interstitial pneumonitis associated with bleomycin therapy. Clinical symptoms and laboratory evaluation of pulmonary status correlated with scintigrap...

journal_title：Cancer

authors： Richman SD,Levenson SM,Bunn PA,Flinn GS,Johnston GS,DeVita VT

更新日期：1975-12-01 00:00:00

abstract：:An astroblastoma in the cerebrum was investigated with the electron microscope. A distinctive feature of the tumor was the radial arrangement of astrocytic cells around the blood vessels. The blood vessels in the tumor commonly exhibited fenestrated endothelial cells. The endothelium was generally surrounded by lamell...

journal_title：Cancer

authors： Kubota T,Hirano A,Sato K,Yamamoto S

更新日期：1985-02-15 00:00:00

abstract：BACKGROUND:Activation of telomerase, a ribonucleoprotein enzyme complex that synthesizes telomere repeats, is associated with acquisition of unlimited cellular proliferation and is commonly detected in human cancer. Measurement of telomerase activity (TA) may provide important information as a diagnostic marker or a pr...

journal_title：Cancer

authors： Shoji Y,Yoshinaga K,Inoue A,Iwasaki A,Sugihara K

更新日期：2000-03-15 00:00:00

abstract：BACKGROUND:Radiotherapy (RT) plays a major role in the management of hemangiopericytomas (HAP). The present analysis evaluates the role of precision RT in the management of HAP of the central nervous system (CNS) and represents one of the largest series of HAP treated with RT that can be found in the literature. METHO...

journal_title：Cancer

authors： Combs SE,Thilmann C,Debus J,Schulz-Ertner D

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Screening over many years is required to optimize reductions in colorectal cancer (CRC) mortality. However, no prior trials have compared strategies for obtaining long-term adherence. METHODS:Systems of Support to Increase Colorectal Cancer Screening and Follow-Up was implemented in an integrated health car...

journal_title：Cancer

authors： Green BB,Anderson ML,Cook AJ,Chubak J,Fuller S,Meenan RT,Vernon SW

更新日期：2017-11-15 00:00:00

abstract：BACKGROUND:The objective of this study was to assess the rate and possible reasons for false-negative (FN) reflex human papillomavirus (HPV)-DNA tests. METHODS:The authors reviewed all ThinPrep cervical specimens that were submitted for reflex HPV-DNA testing using the Digene Hybrid Capture II (HC2) method from Januar...

journal_title：Cancer

authors： Eltoum IA,Chhieng DC,Crowe DR,Roberson J,Jin G,Broker TR

更新日期：2007-06-25 00:00:00

abstract：:A series of 108 prospectively collected human pancreata were evaluated histologically for the presence of acinar cell and ductal lesions. Foci of dysplastic acinar cells were present in 44% of the series. Some of the focal acinar cell abnormalities were similar to atypical acinar cell nodules which have been described...

journal_title：Cancer

authors： Longnecker DS,Shinozuka H,Dekker A

更新日期：1980-02-01 00:00:00

abstract：BACKGROUND:The staging system for non-small cell lung cancer (NSCLC) does not consider tumor burden or number of metastatic sites, although oligometastases are more favorable. METHODS:Using log-rank testing, the authors analyzed overall survival (OS) in 1284 patients newly presenting with metastatic NSCLC by number of...

journal_title：Cancer

authors： Oh Y,Taylor S,Bekele BN,Debnam JM,Allen PK,Suki D,Sawaya R,Komaki R,Stewart DJ,Karp DD

更新日期：2009-07-01 00:00:00

abstract：:This protocol study (SWOG-7431) combining adriamycin and methyl CCNU (MAD) for metastatic sarcomas was initially used on patients who were refractory to cytoxan, vincristine, and/or actinomycin-D. After the initial good results, the study was expanded to include any untreated patients with metastatic sarcoma. The init...

journal_title：Cancer

authors： Rivkin SE,Gottlieb JA,Thigpen T,El Mawla NG,Saiki J,Dixon DO

更新日期：1980-08-01 00:00:00

abstract：:Combined modality therapy consisting of CHOP-Bleo (cyclophosphamide, Adriamycin [doxorubicin], vincristine (Oncovin), prednisone, and bleomycin) and limited-field radiotherapy was given to 47 patients with Stage III and IIIE diffuse large cell lymphomas. Overall 5-year survival and disease-free survival figures are 64...

journal_title：Cancer

authors： Velasquez W,Fuller LM,Oh KK,Hagemeister FB,Sullivan JA,Manning JT,Shullenberger CC

更新日期：1984-04-01 00:00:00

abstract：BACKGROUND:Parathyroid hormone-related protein (PTHrP) is the predominant cause of humoral hypercalcemia of malignancy (HHM). METHODS:Using a PTHrP-specific monoclonal antibody (MoAb), 4B3, the authors investigated the immunohistochemical localization of PTHrP in formalin-fixed and paraffin-embedded sections of normal...

journal_title：Cancer

authors： Gotoh A,Kitazawa S,Mizuno Y,Takenaka A,Arakawa S,Matsumoto O,Kitazawa R,Fujimori T,Maeda S,Kamidono S

更新日期：1993-05-01 00:00:00

abstract：:Although cancer often is referred to as "a disease of the genes," it is indisputable that the (epi)genetic properties of individual cancer cells are highly variable, even within the same tumor. Hence, preexisting resistant clones will emerge and proliferate after therapeutic selection that targets sensitive clones. He...

journal_title：Cancer

authors： Napel S,Mu W,Jardim-Perassi BV,Aerts HJWL,Gillies RJ

更新日期：2018-12-15 00:00:00

abstract：:The development of resistance to purine analogs defines a poor-risk subset of patients with chronic lymphocytic leukemia (CLL). Although in recent years chemoimmunotherapeutic combinations such as fludarabine, cyclophosphamide, and rituximab have induced response rates of 95% in previously untreated patients and incre...

journal_title：Cancer

authors： Tsimberidou AM,Keating MJ

更新日期：2009-07-01 00:00:00

abstract：:Although the existence of subclinical Pneumocystis carinii infection in pediatric patients with solid tumors or hematologic malignancies has been documented, similar data are lacking in adults. In addition, data are needed to define the epidemiology of this agent in adult malignancies to assess the validity of the met...

journal_title：Cancer

authors： Robert NJ,Pifer LL,Niell HB,Woods DR,Neely CL,Miller JH,Churchill H

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND:Interleukin-18 (IL-18) is a novel immunoregulatory cytokine that was known previously as interferon-gamma-inducing factor. IL-18 levels can be used as a serum indicator for monitoring the clinical course of patients with hematologic malignancies and gastric carcinoma. Nitric oxide (NO) is a pleiotropic molec...

journal_title：Cancer

authors： Günel N,Coşkun U,Sancak B,Günel U,Hasdemir O,Bozkurt S

更新日期：2002-08-01 00:00:00

abstract：:An analysis of patterns of relapse from complete remission in patients with non-Hodgkin's lymphoma treated with combination chemotherapy has demonstrated differences between histologic subgroups. Patients with diffuse histiocytic lymphoma who achieved a histologically proven complete remission after 6 months of treatm...

journal_title：Cancer

authors： Schein PS,Chabner BA,Canellos GP,Young RC,DeVita VT Jr

更新日期：1975-02-01 00:00:00

abstract：:In recent years, an increased understanding of T-cell-regulatory mechanisms has led to the development of a novel class of immune-checkpoint inhibitors that have robust clinical activity against a broad array of malignancies-even those that historically were not believed to be sensitive to immune therapy. With this, t...

journal_title：Cancer

authors： Salama AK,Postow MA,Salama JK

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:To evaluate the prevalence and significance of abnormal ovarian findings in asymptomatic postmenopausal women, screening for ovarian cancer with color Doppler ultrasound was performed. METHODS:One thousand three hundred sixty-four asymptomatic women aged 56-61 years (mean, 59 years) were examined by color D...

journal_title：Cancer

authors： Vuento MH,Pirhonen JP,Mäkinen JI,Laippala PJ,Grönroos M,Salmi TA

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:The reliability of cytologic criteria to classify nonproliferative breast lesions (NPBL) is still debated. Sampling error and heterogeneity of breast lesions complicates the histologic correlation of fine-needle aspiration results further. METHODS:To provide optimal cytohistologic correlation, two smears (o...

journal_title：Cancer

authors： Sidawy MK,Tabbara SO,Bryan JA,Poprocky LA,Frost AR

更新日期：2001-04-25 00:00:00

abstract：BACKGROUND:A national data source for identifying patients with cancer enrolled in Medicaid is needed to evaluate cancer care for low-income, publicly insured patients. In this study, a population-based data set of patients diagnosed with cancer and enrolled in Medicaid was created and evaluated. The objective was to c...

journal_title：Cancer

authors： Bradley CJ,Stevens JL,Enewold L,Warren JL

更新日期：2021-01-15 00:00:00