Regulation of expression of the LFA-1 and p150,95 leukocyte integrins: involvement of the CD11a and CD11c gene promoters.

abstract：:Infectious bursal disesase is a highly contagious, wide spread immunosuppressive chicken disease caused by the Infectious Bursal Disease Virus (IBDV). IBDV is a two segmented double-strand RNA virus, member of the Birnaviridae family. In order to study the interaction between IBDV and the immune system, chickens were ...

journal_title：Immunobiology

authors： Carballeda JM,Zoth SC,Gómez E,Gravisaco MJ,Berinstein A

更新日期：2011-09-01 00:00:00

abstract：:Trypanosoma cruzi is a real challenge to the host's immune system, because it requires strong humoral and cellular immune response to remove circulating trypomastigote forms, and to prevent the replication of amastigote forms in tissues, involving many regulator and effector components. This protozoan is responsible f...

journal_title：Immunobiology

authors： Basso B,Marini V

更新日期：2015-03-01 00:00:00

abstract：:Phagocytosis Inhibitory Factor (PIF), a small (< 3000 D) molecule, was partially purified from human red blood cell membranes. This factor inhibits latex phagocytosis by monocytic cells. PIF is not toxic under the experimental conditions employed and the phagocytosis inhibitory activity is reversible since removal of ...

journal_title：Immunobiology

authors： Baranyi L,Baranji K,Yoshida T,Okada N,Okada H

更新日期：1994-12-01 00:00:00

abstract：:Suppressor monocytes, Concanavalin A(ConA)-induced suppressor T cells, and short-lived suppressor lymphocytes have been describe in humans. The present study was performed to evaluate spontaneous suppression in a test system similar to that employed for the demonstration of ConA-induced suppressor cells: Lymphocytes w...

journal_title：Immunobiology

authors： Gattringer C,Huber H,Michlmayr G,Braunsteiner H

更新日期：1981-01-01 00:00:00

abstract：:Atypical hemolytic uremic syndrome (aHUS) is caused mainly by complement dysregulation. Although various defects in the complement system explaining pathophysiology have been described in recent years, the etiology still remains unclear in about thirty percent of cases. In exploring other causes, similar to anti- comp...

journal_title：Immunobiology

authors： Govindarajan S,Rawat A,Ramachandran R,Hans R,Dawman L,Tiewsoh K

更新日期：2020-09-01 00:00:00

abstract：:Lymphocytes from spleen, thymus and lymph nodes from individual young adult (3--4 months) and aged (26--30 months) NMRI mice were stimulated with the mitogens Con A, PHA and LPS. 24 hours later, the number of cell with increased RNA-content (G1 cells) was determined by cytofluorometry. In parallel the 3H-thymidine inc...

journal_title：Immunobiology

authors： Joncourt F,Bettens F,Kristensen F,de Weck AL

更新日期：1981-06-01 00:00:00

abstract：:Gaucher disease (GD) is associated with upregulation of CD1d and MHC-class II expression by monocytes. While the physiological impact of CD1d upregulation remains uncertain, it has been proposed that MHC-class II upregulation is associated with inflammation. Hereby, we show that the decrease in MHC-class II expression...

journal_title：Immunobiology

authors： Balreira A,Cavallari M,Sá Miranda MC,Arosa FA

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:The soluble form of the haptoglobin-hemoglobin (Hp-Hb) scavenger receptor (sCD163) is a specific plasma/serum marker for macrophage activity. Here, we have characterized molecular forms in serum and investigated a role of sCD163 as a binder of Hp-Hb complexes. METHODS:The sCD163 species in serum (from 50 he...

journal_title：Immunobiology

authors： Møller HJ,Nielsen MJ,Maniecki MB,Madsen M,Moestrup SK

更新日期：2010-05-01 00:00:00

abstract：:Prior work demonstrated that a splice variant of SCN5A, a voltage-gated sodium channel gene, acts as a cytoplasmic sensor for viral dsRNA in human macrophages. Expression of this channel also polarizes macrophages to an anti-inflammatory phenotype in vitro and in vivo. Here we utilized global expression analysis of sp...

journal_title：Immunobiology

authors： White CR,Dungan M,Carrithers MD

更新日期：2019-01-01 00:00:00

abstract：:The supernatant from cultures of T cell clones derived from (BALB/c----C3H/He) chimeras suppresses BALB/c anti-C3H/He or BALB/c anti-C57BL/6 MLRs. When we studied the alloantigen specificity of the suppressor activity in culture supernatant, we observed three types of the suppressor activity (i.e., the suppressor acti...

journal_title：Immunobiology

authors： Imamura M,Fujimoto H,Fukuhara T,Kobayashi M,Hashino S,Kasai M,Sakurada K,Miyazaki T

更新日期：1988-04-01 00:00:00

abstract：:Monoclonal mouse anti-Thy-1.2 antibody of IgG3 isotype (MTA) inhibits in a significant and long-term manner the regional graft-versus-host reaction (GVHR) when administered to donors as well as to recipients. The process of sensitization in the reaction of delayed type hypersensitivity to SRBC (DTH) is, on the other h...

journal_title：Immunobiology

authors： Sůla K,Sobotková E,Svobodová M,Nouza K

更新日期：1988-07-01 00:00:00

abstract：:There is extensive evidence for the critical role of reactive oxygen species (ROS) and nitric oxide (NO) produced by phagocytes in development of inflammatory processes and pathogenesis of numerous diseases, including rheumatoid arthritis (RA). Apart from their function as mediators of inflammation and tissue damage, ...

journal_title：Immunobiology

authors： Miletić T,Kovacević-Jovanović V,Vujić V,Stanojević S,Mitić K,Lazarević-Macanović M,Dimitrijević M

更新日期：2007-01-01 00:00:00

abstract：:Peritoneal as well as peripheral blood, but not spleen macrophages inhibit natural killer (NK) cell activity directed against adherent growing target cells. Inhibition was observed with macrophages (Mø): spleen cell ratios as low as 0.01:1. It was independent from the activation status of Mø and was not MHC restricted...

journal_title：Immunobiology

authors： Zöller M,Matzku S

更新日期：1982-12-01 00:00:00

abstract：:Several, and not necessarily alternative, pathogenic mechanisms have been suggested to sustain the thrombophilic diathesis of the anti-phospholipid syndrome. Among them, interference of anti-phospholipid antibodies with cell acting in the coagulation cascade likely plays a major role. Anti-phospholipid antibodies have...

journal_title：Immunobiology

authors： Riboldi P,Gerosa M,Raschi E,Testoni C,Meroni PL

更新日期：2003-01-01 00:00:00

abstract：:A modified immunoperoxidase assay on microscope slides (IPSA) was adopted as a screening procedure for hybridoma supernatants with specificity for human lymphocyte subpopulations. The method proved to be suitable for testing a large number of hybridomas with a minimum of cells and reagents. In addition, the slide-tech...

journal_title：Immunobiology

authors： Morich FJ,Momburg F,Moldenhauer G,Hartmann KU,Bross KJ

更新日期：1983-03-01 00:00:00

abstract：:P2X7 receptor activation is involved in a number of pro-inflammatory responses in macrophages and other immune cells. Their expression can be positively modulated with lipopolysaccharide (LPS) and TNFalpha, reinforcing their role during inflammation. We investigated the effect of substances capable of recruiting macro...

journal_title：Immunobiology

authors： Marques da Silva C,Miranda Rodrigues L,Passos da Silva Gomes A,Mantuano Barradas M,Sarmento Vieira F,Persechini PM,Coutinho-Silva R

更新日期：2008-01-01 00:00:00

abstract：PROBLEM:NK lymphocytes play critical yet poorly defined role in implantation and during development in early pregnancy. METHODS OF STUDY:Recently, we showed that the proportion of NK that expressed CD69⁺ after incubation with K562 (CD69(stim)) cells reflected the NK population excitation potential. In the present stud...

journal_title：Immunobiology

authors： Dons'koi BV,Chernyshov VP,Sirenko VY,Strelko GV,Osypchuk DV

更新日期：2014-03-01 00:00:00

abstract：:Cytokines play critical roles in the pathogenesis of Behçet's disease (BD). They mediated many of the effectors and regulatory functions of immune and inflammatory responses. Many studies have linked Interleukin-6 (IL-6) and Interleukin-10 (IL-10) pathologically to BD. Thus, this study aimed to investigate the associa...

journal_title：Immunobiology

authors： Talaat RM,Ashour ME,Bassyouni IH,Raouf AA

更新日期：2014-08-01 00:00:00

abstract：:We hypothesized that anti-citrullinated protein antibodies (ACPAs) could affect the expression of miRNAs in monocytes and contribute to the inflammatory responses in rheumatoid arthritis (RA). The expression profiles of 270 human miRNAs, co-cultured with ACPAs or human immunoglobulin G (IgG), were analyzed using real-...

journal_title：Immunobiology

authors： Lai NS,Yu HC,Yu CL,Koo M,Huang HB,Lu MC

更新日期：2015-12-01 00:00:00

abstract：:Complement component C6 is a part of the lytic membrane attack complex formed during complement activation. Animal modeling to define the role of C5a vs. C5b-9 in human disease has used rodents deficient in C6, yet the molecular basis for the deficiencies has not been ascertained. Oligonucleotides derived from a 493 b...

journal_title：Immunobiology

authors： Bhole D,Stahl GL

更新日期：2004-01-01 00:00:00

abstract：:Ficolins are a group of proteins containing both a collagen-like domain and a fibrinogen-like domain and are found in varying tissues. Ficolins present in sera have a lectin activity toward N-acetylglucosamine through their fibrinogen-like domains. The domain organizations between ficolins and mannose-binding lectin (...

journal_title：Immunobiology

authors： Matsushita M,Fujita T

更新日期：2002-09-01 00:00:00

abstract：:The goal of our work was to titer the IgG, IgM and IgA in Pentaglobin® (a preparation enriched in IgM), targeting specific surface antigens of Gram-positive and Gram-negative bacteria as well as a C. albicans strain. Lipopolysaccharides from Gram-negative bacteria, peptidoglycan and lipoteichoic acid from the other mi...

journal_title：Immunobiology

authors： Stracquadanio S,Lo Verde F,Cialfi A,Zega A,Stefani S,Cafiso V

更新日期：2020-03-01 00:00:00

abstract：:Previous work has shown that purified rat macrophages lack both accessory activity for T lymphocyte responses to mitogens and stimulatory activity in a mixed leukocyte reaction, in marked contrast to the potent activity of dendritic cells. This study was designed to re-evaluate macrophages as accessory cells by treati...

journal_title：Immunobiology

authors： Bowers WE,Ruhoff MS,Goodell EM,Stoltenborg JK

更新日期：1988-02-01 00:00:00

abstract：:Shigella spp. are known to penetrate the colonic epithelial cells causing shigellosis, which results in production of convalescent antibodies against porin, the surface exposed major outer membrane protein. Porin has been categorized as primarily TLR2-ligand and here we validated its signaling procedure in colonic INT...

journal_title：Immunobiology

authors： Mukherjee S,Sinha D,Ghosh AK,Biswas T

更新日期：2014-05-01 00:00:00

abstract：:Dendritic cells (DC) are efficient antigen presenting cells with the ability to activate naïve T cells. Murine DC represent a heterogeneous population that can be subdivided into distinct subsets, including the conventional DC (cDC) which are either CD4(-)CD8(-) (DN), CD4(+)CD8(-) (CD4+) or CD4(-)CD8(+) (CD8+) subsets...

journal_title：Immunobiology

authors： Proietto AI,O'Keeffe M,Gartlan K,Wright MD,Shortman K,Wu L,Lahoud MH

更新日期：2004-01-01 00:00:00

abstract：:The recent purification and cloning of T cell-derived growth factors, should lead to rapid progress in delineating their role in the generation of accessory cells and the regulation of their function. The techniques that have allowed detailed in vitro studies of the T-dependent mast cells, should be generally applicab...

journal_title：Immunobiology

authors： Schrader JW,Clark-Lewis I,Wong GH

更新日期：1984-12-01 00:00:00

abstract：:In a subgroup of CVID T cell abnormalities have been reported. Peripheral blood T lymphocytes from patients with common variable immunodeficiency (CVID) and blood donors were examined for expression of CD8alpha, CD8beta and CD28. In CVID, three CD8+ T cells could be defined: CD8beta(high)CD28+ (expressing CD8beta at a...

journal_title：Immunobiology

authors： Werwitzke S,Drescher B,Schmidt RE,Witte T

更新日期：2000-08-01 00:00:00

abstract：:In contrast to murine spleen M phi, resident peritoneal M phi from health mice express very little Forssman glycolipid antigen (Fo). The following experiments suggest that Fo expression by peritoneal M phi may be associated with inflammation. Balb/c and CBA/J mice were given inflammatory stimuli by i.p. injection of l...

journal_title：Immunobiology

authors： von Kleist R,Schmitt E,Westermann J,Mühlradt PF

更新日期：1990-06-01 00:00:00

abstract：:Gut microbiota and probiotic strains play an important role in oral tolerance by modulating regulatory and effector cell components of the immune system. We have previously described the ability of Lactobacilli to influence both the innate and adaptive immunity to wheat gluten, a food antigen, in mouse. In this study,...

journal_title：Immunobiology

authors： Ogita T,Bergamo P,Maurano F,D'Arienzo R,Mazzarella G,Bozzella G,Luongo D,Sashihara T,Suzuki T,Tanabe S,Rossi M

更新日期：2015-06-01 00:00:00

abstract：:Culture supernatants (CS) from Hodgkin derived cell lines have previously been shown to contain colony stimulating activity (CSF) for human cord blood cells, fetal bone marrow and fetal liver cells. In this study 3-day CS from four Hodgkin lines (L428, L538, L540, L591) and two sublines (L428KS, L428KSA) were examined...

journal_title：Immunobiology

authors： Kortmann C,Burrichter H,Monner D,Jahn G,Diehl V,Peter HH

更新日期：1984-05-01 00:00:00