Spontaneous eye blink rate in winter seasonal affective disorder.


:We investigated spontaneous eye-blink rates in 19 drug-free patients with winter seasonal affective disorder (SAD) and 18 normal control subjects. At baseline, there were no significant differences between the two groups (mean +/- SD blink rate: 15/minute +/- 8 vs. 15/minute +/- 7). Light therapy (10,000 lux: 1 hour each morning for 1 week) produced no significant change in mean (+/- SD) blink rates either in 10 SAD patients (13/minute +/- 8 vs. 10/minute +/- 7) or in 12 normal control subjects (15/minute +/- 6 vs. 14/minute +/- 6). A post hoc exploratory analysis of the effect of light therapy on premenopausal female subjects (5 patients and 9 control subjects) showed a significant decrease in mean (+/- SD) blink rate in the patients after treatment (17 +/- 6 vs. 12 +/- 8 compared with 15 +/- 7 vs. 16 +/- 5). These results do not support the idea that an elevated blink rate may be a general biological marker in SAD, but they suggest a possible link between light treatment and mechanisms that regulate blink rate in premenopausal SAD patients.


Psychiatry Res


Psychiatry research


Barbato G,Moul DE,Schwartz P,Rosenthal NE,Oren DA




Has Abstract


1993-04-01 00:00:00














  • Expressed Emotion and behaviourally controlling interactions in the daily life of dyads experiencing psychosis.

    abstract::While research using Experience Sampling Methodology (ESM) suggests that, in general, contact with relatives or friends may be protective for psychotic experiences, contact with high-Expressed Emotion (high-EE) relatives can have adverse consequences for patients. This study investigated whether contact with high-EE r...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Vasconcelos E Sa D,Wearden A,Hartley S,Emsley R,Barrowclough C

    更新日期:2016-11-30 00:00:00

  • What do childhood attention deficit/hyperactivity symptoms in depressed adults tell us about the bipolar spectrum?

    abstract:BACKGROUND:This study aims to establish if adult patients with major depressive disorder (MDD) and childhood Attention Deficit/Hyperactivity disorder (ADHD) symptoms would be more frequently within the bipolar spectrum than depressed patients without childhood ADHD. METHODS:This study was carried out in outpatients re...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Purper-Ouakil D,Porfirio MC,Le Strat Y,Falissard B,Gorwood P,Masi G

    更新日期:2017-03-01 00:00:00

  • Basal ganglia volume in adults with Down syndrome.

    abstract::This study was designed to determine the effects of aging on the volume of the basal ganglia in individuals with Down syndrome (DS) and to examine the relationship between basal ganglia volumes, neuropsychological test performance, and dementia status in this population. Subjects were 32 adults with DS. Basal ganglia ...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Aylward EH,Li Q,Habbak QR,Warren A,Pulsifer MB,Barta PE,Jerram M,Pearlson G

    更新日期:1997-05-16 00:00:00

  • Trait anxiety is associated with a decreased visual working memory capacity for faces.

    abstract::Recent work has suggested that anxiety restricts working memory capacity, which may underlie a wide range of cognitive symptoms in anxiety. However, previous literature on the anxiety-visual working memory association yielded mixed results, with some studies demonstrating an anxiety-related increase in visual working ...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Yao N,Chen S,Qian M

    更新日期:2018-12-01 00:00:00

  • What is the prevalence of autism spectrum disorder and ASD traits in psychosis? A systematic review.

    abstract::There is increasing evidence to suggest both a symptomatic overlap and a clinically significant degree of co-occurrence between Autism Spectrum Disorders (ASD) and psychotic disorders such as schizophrenia but the nature of such relationships remain unclear. We reviewed the literature reporting prevalence rates of Aut...

    journal_title:Psychiatry research

    pub_type: 杂志文章,评审


    authors: Kincaid DL,Doris M,Shannon C,Mulholland C

    更新日期:2017-04-01 00:00:00

  • Dexamethasone increases plasma HVA but not MHPG in normal humans.

    abstract::Several recent studies in animals and man indicate that corticosteroids may alter catecholaminergic activity in both the peripheral and central nervous systems. We administered 1 mg of the synthetic glucocorticoid, dexamethasone, to 12 drug-free healthy volunteers and measured plasma homovanillic acid (HVA) and 3-meth...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Wolkowitz OM,Sutton ME,Doran AR,Labarca R,Roy A,Thomas JW,Pickar D,Paul SM

    更新日期:1985-10-01 00:00:00

  • 123I-ADAM SPECT imaging of serotonin transporter binding in patients with night eating syndrome: a preliminary report.

    abstract::Night eating syndrome (NES) represents a delay in the circadian pattern of food intake, manifested by evening hyperphagia and/or nocturnal awakenings accompanied by ingestions of food. A neurobiological marker of NES has been implicated with the recently discovered therapeutic response to the selective serotonin reupt...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Lundgren JD,Newberg AB,Allison KC,Wintering NA,Ploessl K,Stunkard AJ

    更新日期:2008-04-15 00:00:00

  • County-level social factors and schizophrenia: A multilevel study of 1.9 million Chinese adults.

    abstract::There is little evidence on the association between area-level social factors and schizophrenia in China. This study aimed to investigate the relationship between county-level social factors and schizophrenia in Chinese adults aged 18 years old and above. We obtained data from the Second China National Sample Survey o...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Luo Y,Guo C,Zhang L,Pang L,Zhao X,Zheng X

    更新日期:2019-01-01 00:00:00

  • Association between cognitive performance and striatal dopamine binding is higher in timing and motor tasks in patients with schizophrenia.

    abstract::The basal ganglia have received increasing attention with regard to their role in time pacing, motor function and other components of cognition. The aim of this study was to test whether the finer the motor activity and/or time perception performance were, the higher the striatal dopamine D(2) binding would be. Single...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Yang YK,Yeh TL,Chiu NT,Lee IH,Chen PS,Lee LC,Jeffries KJ

    更新日期:2004-09-15 00:00:00

  • Lack of sex differences in striatal dopamine D2 receptor binding in drug-naive schizophrenic patients: an IBZM-SPECT study.

    abstract::Differences in antipsychotic treatment response, clinical course and outcome of schizophrenia could be related to gender-related cerebral differences in anatomy and function. The aim of the study was to assess sex differences in the striatal dopamine D2 receptor binding in 15 drug-naive schizophrenic patients (seven m...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Parellada E,Lomeña F,Catafau AM,Bernardo M,Font M,Fernández-Egea E,Pavía J,Gutierrez F

    更新日期:2004-01-15 00:00:00

  • A computer program for assessing interexaminer agreement when multiple ratings are made on a single subject.

    abstract::This report describes a computer program for applying a new statistical method for determining levels of agreement, or reliability, when multiple examiners evaluate a single subject. The statistics that are performed include the following: an overall level of agreement, expressed as a percentage, that takes into accou...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Cicchetti DV,Showalter D

    更新日期:1997-08-29 00:00:00

  • Gray matter density reduction in the insula in fire survivors with posttraumatic stress disorder: a voxel-based morphometric study.

    abstract::Voxel-based morphometry (VBM) is an objective whole-brain technique for characterizing regional cerebral volume and tissue concentration differences in structural magnetic resonance images. In the current study, we used VBM to examine possible cerebral gray matter abnormalities in patients with posttraumatic stress di...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Chen S,Xia W,Li L,Liu J,He Z,Zhang Z,Yan L,Zhang J,Hu D

    更新日期:2006-01-30 00:00:00

  • High Intensity Interval training (HIIT) for people with severe mental illness: A systematic review & meta-analysis of intervention studies- considering diverse approaches for mental and physical recovery.

    abstract::There is a mortality gap of 15 to 20 years for people with severe mental illness (SMI - psychotic spectrum, bipolar, major depressive disorders). Modifiable risk factors include inactivity and low cardiorespiratory fitness (CRF). Exercise can improve mental and physical outcomes; optimal type and intensity of exercise...

    journal_title:Psychiatry research

    pub_type: 杂志文章,meta分析


    authors: Korman N,Armour M,Chapman J,Rosenbaum S,Kisely S,Suetani S,Firth J,Siskind D

    更新日期:2020-02-01 00:00:00

  • Facial trustworthiness perception bias elevated in individuals with PTSD compared to trauma exposed controls.

    abstract::Posttraumatic stress disorder (PTSD) research has focused largely on fear processing. However, interpersonal trauma exposure can also impact interpersonal functioning and the perception of the trustworthiness of others. The present study examined facial perceptions of fearfulness and trustworthiness in individuals wit...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Fertuck EA,Tsoi F,Grinband J,Ruglass L,Melara R,Hien DA

    更新日期:2016-03-30 00:00:00

  • Early ERP components to emotional facial expressions in young adult victims of childhood maltreatment.

    abstract::The ability to appropriately recognize the facial expression of emotions is essential for the development of adaptive functioning. Studies suggest that maltreated children are hypersensitive to expression of anger. However, the neural mechanism of emotional face processing in young adults with a history of childhood m...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Fang J,Wang S,Liu J,Gong J

    更新日期:2019-05-01 00:00:00

  • The use of narrative sampling in the assessment of social cognition: the Narrative of Emotions Task (NET).

    abstract::Social cognitive deficits in schizophrenia are well documented and related to functional outcome. Current social cognition measures are often not psychometrically validated, too heterogeneous for standardization, and focus principally on one domain of social cognition rather than the simultaneous activation of multipl...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Buck B,Ludwig K,Meyer PS,Penn DL

    更新日期:2014-07-30 00:00:00

  • Effects of venlafaxine versus lithium monotherapy on quality of life in bipolar II major depressive disorder: Findings from a double-blind randomized controlled trial.

    abstract::Bipolar disorder is associated with decreased quality of life, especially during depressive episodes. There are few studies that have examined whether quality of life improves following pharmacological treatments of bipolar depression. In this exploratory study, we examined the effects of antidepressant versus mood st...

    journal_title:Psychiatry research

    pub_type: 杂志文章,随机对照试验


    authors: Lorenzo-Luaces L,Amsterdam JD

    更新日期:2018-01-01 00:00:00

  • Motor mechanisms in schizophrenic patients with tardive dyskinesia.

    abstract::A specific aspect of the motor output of patients with tardive dyskinesia was investigated with an experimental procedure referenced in force control function (i.e., the maintenance of sustained force output). We hypothesized that response output (button press) at a given level would be significantly altered when prec...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Vrtunski PB,Alphs LD,Meltzer HY

    更新日期:1994-10-01 00:00:00

  • Internalized stigma among psychiatric outpatients: Associations with quality of life, functioning, hope and self-esteem.

    abstract::This study aimed to: (i) determine the prevalence, socio-demographic and clinical correlates of internalized stigma and (ii) explore the association between internalized stigma and quality of life, general functioning, hope and self-esteem, among a multi-ethnic Asian population of patients with mental disorders. This ...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Picco L,Pang S,Lau YW,Jeyagurunathan A,Satghare P,Abdin E,Vaingankar JA,Lim S,Poh CL,Chong SA,Subramaniam M

    更新日期:2016-12-30 00:00:00

  • Neural responses to emotional stimuli in comorbid borderline personality disorder and bipolar depression.

    abstract::Borderline personality disorder (BPD) is a severe clinical condition characterised by different maladaptive traits such as impulsivity and affective lability. Mood and emotion dysregulation are core features of affective disorders. Indeed patients affected by mood disorder (MD) have a significantly higher prevalence o...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Radaelli D,Poletti S,Dallaspezia S,Colombo C,Smeraldi E,Benedetti F

    更新日期:2012-07-30 00:00:00

  • Life and treatment goals of individuals hospitalized for first-episode nonaffective psychosis.

    abstract::First-episode psychosis typically emerges during late adolescence or young adulthood, interrupting achievement of crucial educational, occupational, and social milestones. Recovery-oriented approaches to treatment may be particularly applicable to this critical phase of the illness, but more research is needed on the ...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Ramsay CE,Broussard B,Goulding SM,Cristofaro S,Hall D,Kaslow NJ,Killackey E,Penn D,Compton MT

    更新日期:2011-10-30 00:00:00

  • Neurological soft signs in Chinese adolescents with antisocial personality traits.

    abstract::The current study was designed to explore the specific relationship between neurologic soft signs (NSSs) and characteristics of antisocial personality traits in adolescents, and to investigate particular NSSs linked to certain brain regions in adolescents with antisocial personality traits. The research was conducted ...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Wang X,Cai L,Li L,Yang Y,Yao S,Zhu X

    更新日期:2016-09-30 00:00:00

  • Psychotic symptoms in COVID-19 patients. A retrospective descriptive study.

    abstract::Psychotic symptoms have been related to other coronavirus infections. We conducted a single-centre retrospective and observational study to describe new-onset psychotic episodes in COVID-19 patients. Ten patients infected by the novel coronavirus with psychotic symptoms and no previous history of psychosis were identi...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Parra A,Juanes A,Losada CP,Álvarez-Sesmero S,Santana VD,Martí I,Urricelqui J,Rentero D

    更新日期:2020-09-01 00:00:00

  • Differential suicide risk factors in rural middle and high school students.

    abstract::Few studies have examined risk factors associated with suicidal ideation and attempts among younger adolescents compared to their high-school aged counterparts. To gain a better understanding of unique risk factors associated with suicidal ideation and attempts among middle-school aged students, the current study empl...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Lear MK,Perry KM,Stacy SE,Canen EL,Hime SJ,Pepper CM

    更新日期:2020-02-01 00:00:00

  • Short-term heart rate variability in older patients with newly diagnosed depression.

    abstract::Dysfunction of the autonomic nervous system has been considered to be a risk factor for major depressive disorder (MDD) and cardiovascular disease (CVD). The aim of this study was to evaluate short-term heart rate variability (HRV) in elderly patients with newly diagnosed MDD. Thirty MDD patients over 60 years old new...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Ha JH,Park S,Yoon D,Kim B

    更新日期:2015-04-30 00:00:00

  • Gender differences in schizophrenia: A multicentric study from three Latin-America countries.

    abstract::This study was aimed to explore clinical differences between women and men with schizophrenia (SZ) in Latin-America. It was conducted in public mental health centers in Bolivia, Peru and Chile. Two hundred forty-seven SZ patients participated in the study, 83 (33.6%) were women and 115 (46.6%) were Aymara. Compared to...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Caqueo-Urízar A,Fond G,Urzúa A,Boyer L

    更新日期:2018-08-01 00:00:00

  • Cavum septum pellucidum in pediatric traumatic brain injury.

    abstract::The cavum septum pellucidum (CSP) is a fluid-filled cavity in the thin midline structure of the septum pellucidum. The CSP has been linked to several neurodevelopmental disorders, but it also occurs as a result of head injury. The aims were to assess the presence and characterization of the CSP in youth with traumatic...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Silk T,Beare R,Crossley L,Rogers K,Emsell L,Catroppa C,Beauchamp M,Anderson V

    更新日期:2013-09-30 00:00:00

  • Application of the seven-factor model of personality to early childhood.

    abstract::The seven-factor model of personality developed by Cloninger and colleagues describes personality as a function of developmental aspects of character superimposed on heritable dimensions of temperament. The objective of this study was to determine whether this model could be applied to early childhood. We tested a pre...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Constantino JN,Cloninger CR,Clarke AR,Hashemi B,Przybeck T

    更新日期:2002-04-15 00:00:00

  • First-night effect in the chronic fatigue syndrome.

    abstract::Since the magnitude of the first-night effect has been shown to be a function of medical conditions and of settings in which polysomnographies are performed, it is essential to evaluate the habituation phenomenon in each case in order to determine the optimal recording methodology. A first-night effect was evidenced i...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Le Bon O,Minner P,Van Moorsel C,Hoffmann G,Gallego S,Lambrecht L,Pelc I,Linkowski P

    更新日期:2003-09-30 00:00:00

  • Dimensional assessment of posttraumatic stress disorder in DSM-5.

    abstract::The present paper describes the development of the National Stressful Events Survey for PTSD-Short Scale (NSESSS-PTSD), a new self-report scale for PTSD that is brief (9 items), free of copyright restrictions, and consistent with DSM-5 diagnostic criteria. Study 1 describes the development of the NSESSS-PTSD scale ite...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: LeBeau R,Mischel E,Resnick H,Kilpatrick D,Friedman M,Craske M

    更新日期:2014-08-15 00:00:00