Does minimizing neuroleptic dosage influence hyponatremia?

Abstract:

:Neuroleptic dosage was reduced by 10% every 2 weeks in five male hyponatremic polydipsic patients with schizophrenia. Mean dose fell from 1980 +/- 1289 to 631 +/- 135 chlorpromazine equivalents/day over a mean of 12.2 weeks until behavioral relapse occurred. During this time, serum sodium did not vary from baseline levels (132.9 +/- 4.9 mEq/1), suggesting that minimizing neuroleptic dose does not alter the severity of hyponatremia in these patients.

journal_name

Psychiatry Res

journal_title

Psychiatry research

authors

Canuso CM,Goldman MB

doi

10.1016/0165-1781(96)02793-x

subject

Has Abstract

pub_date

1996-07-31 00:00:00

pages

227-9

issue

2-3

eissn

0165-1781

issn

1872-7123

pii

0165-1781(96)02793-X

journal_volume

63

pub_type

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