Abstract：
:We have studied fasting plasma tryptophan (TRP) levels and tryptophan/large neutral amino acid (TRP/LNAA) ratios in 12 patients with obsessive-compulsive disorder (OCD) and 12 patients with OCD and a coexisting current diagnosis of major depressive disorder (OCD-MDD). Assessments were made at baseline and after 6 weeks of treatment with fluvoxamine. OCD-MDD patients had significantly lower baseline TRP levels and TRP/LNAA ratios than OCD patients. After 6 weeks of fluvoxamine treatment, OCD-MDD patients had significant increases in plasma TRP and TRP/LNAA ratio, whereas OCD patients had non-significant decreases. Our data suggest that a major depressive syndrome could be a state variable affecting the changes in plasma TRP and TRP/LNAA ratio in OCD patients.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Bellodi L,Erzegovesi S,Bianchi L,Lucini V,Conca R,Lucca Adoi
10.1016/s0165-1781(96)02961-7subject
Has Abstractpub_date
1997-03-03 00:00:00pages
9-15issue
1eissn
0165-1781issn
1872-7123pii
S0165178196029617journal_volume
69pub_type
杂志文章abstract：:Panic disorder (PD) and social phobia (SP) share many clinical, demographic and biological characteristics. To investigate the relationships between the two disorders, the responses to inhalation of a 35% carbon-dioxide (CO2) and 65% oxygen (O2) gas mixture were assessed. Sixteen patients with PD, 16 patients with SP,...
journal_title：Psychiatry research
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0165-1781(97)00038-3
更新日期：1997-06-16 00:00:00
abstract：:Depressive disorders are common, heterogeneous conditions involving physical and psychological symptoms, and substantial impairment in quality of life (QoL). However, relationships between depressive symptoms and QoL are poorly understood, and little research has directly compared relationships between subtypes of dep...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2020.113049
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2013.07.036
更新日期：2014-01-30 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2009.03.010
更新日期：2009-10-30 00:00:00
abstract：:There is a considerable literature linking aspects of experienced parenting to later personality disorders. Because dimensionally measured personality disorders are associated with variations in normal personality traits, it is important to understand the contribution of parenting experienced in childhood to later nor...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0165-1781(02)00128-2
更新日期：2002-08-05 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.psychres.2007.04.001
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journal_title：Psychiatry research
pub_type： 杂志文章,评审
doi：10.1016/j.psychres.2014.12.005
更新日期：2015-02-28 00:00:00
abstract：:Abnormalities of both the spontaneous and the stimulated release of growth hormone (GH) have been described in patients with endogenous depression. In this study, six unmedicated male patients with endogenous depression (ICD 296.1/3) were compared with six age-matched healthy men. Levels of GH were determined at 15-mi...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(93)90080-z
更新日期：1993-06-01 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2007.10.003
更新日期：2008-04-15 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(93)90114-v
更新日期：1993-07-01 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章,meta分析,评审
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更新日期：2018-01-01 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2008.06.012
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journal_title：Psychiatry research
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.psychres.2008.03.016
更新日期：2009-07-30 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2017.12.060
更新日期：2018-03-01 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2008.10.023
更新日期：2009-12-30 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0165-1781(98)00055-9
更新日期：1998-08-17 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2014.08.054
更新日期：2014-09-04 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2010.12.016
更新日期：2011-10-30 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2004.01.007
更新日期：2004-11-15 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：
更新日期：1992-11-01 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2015.06.010
更新日期：2015-08-30 00:00:00
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journal_title：Psychiatry research
pub_type： 临床试验,杂志文章
doi：10.1016/j.psychres.2009.09.003
更新日期：2011-02-28 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2004.12.015
更新日期：2008-01-15 00:00:00
abstract：:Several lines of evidence suggest that lactate metabolism may be altered in panic disorder. We recently reported exaggerated increases in serum lactate in panic patients following hyperventilation during glucose infusion. In the current study, lactate metabolism was stimulated by hyperventilation following glucose ing...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(91)90020-p
更新日期：1991-09-01 00:00:00
abstract：:The objectives of the present study were to describe the prescribing patterns for psychosocial therapies in routine clinical practice and to assess the impact of psychoeducation on symptoms and social autonomy of patients with schizophrenia. We used data from the nationwide French ESPASS observational cohort study inc...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2016.10.048
更新日期：2017-01-01 00:00:00
abstract：:There is growing concern over the potential for increased suicide risk in vulnerable populations as the COVID-19 pandemic unfolds. To contextualize this risk during the first weeks of the nationwide lockdown efforts, we had 1,013 U.S. adults complete questionnaires assessing worries over COVID-19, insomnia severity, a...
journal_title：Psychiatry research
pub_type： 信件
doi：10.1016/j.psychres.2020.113134
更新日期：2020-08-01 00:00:00
abstract：:Neuropsychological performance was examined in a sample of 100 children between the ages of 6 and 18 years who met DSM-III-R criteria for Tourette's syndrome. Neuropsychological test scores were converted to age-corrected t scores based on published normative data. Ratings of Tourette's symptoms were also obtained. Th...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(90)90150-4
更新日期：1990-07-01 00:00:00
abstract：:Chronic imipramine administration decreases the density of serotonin S2 and beta-adrenergic receptors. The mode of action is not clear but might be assumed to be a result of imipramine interacting with its high affinity binding sites on presynaptic serotonin neurons. To investigate this possibility and the role of the...
journal_title：Psychiatry research
pub_type： 杂志文章
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更新日期：1983-07-01 00:00:00
abstract：:The current study was a systematic review examining probable posttraumatic stress disorder (PTSD) in first responders following man-made mass violence. A systematic literature search yielded 20 studies that fit the inclusion criteria. The prevalence rates of probable PTSD across all 20 studies ranged from 1.3% to 22.0...
journal_title：Psychiatry research
pub_type： 杂志文章,评审
doi：10.1016/j.psychres.2015.06.015
更新日期：2015-09-30 00:00:00
abstract：:Objective measures of experimentally induced aggressiveness were evaluated in heroin-dependent patients (HDP), 15 receiving buprenorphine (BUP) and 15 receiving methadone (METH) treatment. HDP were randomly assigned to BUP and METH groups. Fifteen healthy subjects (CONT) were included in the study as controls. During ...
journal_title：Psychiatry research
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.psychres.2006.02.013
更新日期：2007-01-15 00:00:00
