Abstract：
:Coelomic fluid from the earthworm Lumbricus terrestris is known to contain immunoactive cells and molecules involved in immune defense. To assess the ability of such molecules to form precipitating complexes with anti-human immunoglobulins, radial immunodiffusion experiments were conducted. Anti-human IgG, anti-human IgA, and anti-human IgM were the three immunoglobulins examined. Earthworm coelomic fluid was found to contain molecules that bind anti-IgA and anti-IgG. No precipitation reactions were observed with anti-IgM. Earthworm coelomic fluid diluted 1:8 still formed precipitating complexes with anti-IgA and anti-IgG. Elucidation of the earthworm binding site on anti-IgG and anti-IgA could make earthworm coelomic fluid a valuable reagent in immunological, chemical and biological research.
journal_name
Immunol Lettjournal_title
Immunology lettersauthors
Eyambe GSdoi
10.1016/0165-2478(93)90081-csubject
Has Abstractpub_date
1993-02-01 00:00:00pages
135-9issue
2eissn
0165-2478issn
1879-0542pii
0165-2478(93)90081-Cjournal_volume
35pub_type
杂志文章abstract：:The question is still unresolved whether in insulin-dependent (type I) diabetes T-lymphocytes mediate an autoimmune response towards pancreatic islets. We now present direct evidence in an animal model for autoimmune T-lymphocytes with specificity for islet antigens. Mice of strain C57BL/6 were immunized repeatedly wi...
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更新日期：2015-12-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2012-03-30 00:00:00
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journal_title：Immunology letters
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更新日期：1997-06-01 00:00:00
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更新日期：1989-09-01 00:00:00
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journal_title：Immunology letters
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更新日期：1992-01-01 00:00:00
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journal_title：Immunology letters
pub_type： 杂志文章
doi：10.1016/0165-2478(84)90011-7
更新日期：1984-01-01 00:00:00
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journal_title：Immunology letters
pub_type： 杂志文章
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更新日期：2010-02-16 00:00:00
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journal_title：Immunology letters
pub_type： 杂志文章
doi：10.1016/0165-2478(96)02600-4
更新日期：1996-10-01 00:00:00
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journal_title：Immunology letters
pub_type： 杂志文章
doi：10.1016/0165-2478(94)90086-8
更新日期：1994-10-01 00:00:00
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journal_title：Immunology letters
pub_type： 杂志文章
doi：10.1016/0165-2478(93)90104-a
更新日期：1993-06-01 00:00:00
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journal_title：Immunology letters
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更新日期：2020-04-01 00:00:00
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journal_title：Immunology letters
pub_type： 杂志文章
doi：10.1016/j.imlet.2013.12.003
更新日期：2014-03-01 00:00:00
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journal_title：Immunology letters
pub_type： 杂志文章
doi：10.1016/s0165-2478(98)00061-3
更新日期：1998-09-01 00:00:00
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journal_title：Immunology letters
pub_type： 杂志文章
doi：10.1016/0165-2478(96)02550-3
更新日期：1996-06-01 00:00:00
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journal_title：Immunology letters
pub_type： 杂志文章
doi：10.1016/j.imlet.2005.05.013
更新日期：2005-11-15 00:00:00
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journal_title：Immunology letters
pub_type： 杂志文章,评审
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更新日期：2010-03-10 00:00:00
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journal_title：Immunology letters
pub_type： 杂志文章
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更新日期：2014-05-01 00:00:00
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journal_title：Immunology letters
pub_type： 杂志文章
doi：10.1016/0165-2478(85)90114-2
更新日期：1985-01-01 00:00:00
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更新日期：2007-02-15 00:00:00
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journal_title：Immunology letters
pub_type： 杂志文章
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更新日期：1999-08-03 00:00:00
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journal_title：Immunology letters
pub_type： 杂志文章
doi：10.1016/j.imlet.2006.11.007
更新日期：2007-02-15 00:00:00
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journal_title：Immunology letters
pub_type： 杂志文章
doi：10.1016/s0165-2478(98)00002-9
更新日期：1998-04-01 00:00:00
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journal_title：Immunology letters
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更新日期：2020-12-01 00:00:00
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journal_title：Immunology letters
pub_type： 杂志文章
doi：10.1016/j.imlet.2009.06.002
更新日期：2009-08-15 00:00:00
abstract：:Both the sporozoites and the erythrocytic stages can modulate the hepatic phase by cytokines, notably IFN-gamma, TNF and IL-6, either directly or as a result of a cascade of events, and by MHC-restricted and antibody-dependent cell-mediated cytotoxicity. The role played by CD8+ T cells in inducing protective immunity ...
journal_title：Immunology letters
pub_type： 杂志文章,评审
doi：10.1016/0165-2478(90)90093-6
更新日期：1990-08-01 00:00:00
