Clinical features and treatment prognosis of infertile males with robertsonian translocation.

Abstract:

BACKGROUND:The principle of treating male infertility in those with chromosomal aberrations should change according to progress in treatment modalities. METHODS:In this study, ten patients with Robertsonian translocation were assessed for their cytogenetic and clinical characteristics to establish guidelines for treating these patients. RESULTS:In 8 of 10 cases, chromosomes 13 and 14 were involved. In 4 of 10 cases (40%), their wives became pregnant, including two spontaneously. All newborns were without any deformities including one boy who was shown to have a normal karyotype. CONCLUSION:Infertility treatment of patients with Robertsonian translocation should be optimistically performed on the basis of proper informed consent.

journal_name

Urol Int

journal_title

Urologia internationalis

authors

Kondoh N,Matsumiya K,Nakamura Y,Koga M,Nishimura K,Kitamura M,Takeyama M,Okuyama A

doi

10.1159/000066122

subject

Has Abstract

pub_date

2002-01-01 00:00:00

pages

309-12

issue

4

eissn

0042-1138

issn

1423-0399

pii

66122

journal_volume

69

pub_type

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