Abstract:
PURPOSE:The study aimed to investigate clinical factors associating with occult lymph node micrometastases (pN1 disease) in a contemporary cohort of organ-confined prostate cancer (PCA) patients staged as cN0. MATERIALS AND METHODS:The study evaluated 184 consecutive patients. Associations of clinical factors with pN1 disease were assessed by multivariate logistic regression analysis. RESULTS:Lymph node invasion was detected in 33 cases (17.9%). Independent factors associating with pN1 status were prostate specific antigen (PSA; OR 1.054; p = 0.004), percentage of positive biopsy cores (PPC; OR 1.030; p = 0.013), and biopsy Gleason pattern (bGP) >4 + 3 (OR 3.666; p = 0.004). A clinical model predicting the risk of pN1 disease identified 4 prognostic groups of pN1 disease. CONCLUSIONS:In a contemporary cohort of PCA patients, lymph node invasion was detected in 17.9% of cases. An independent clinical disease showed that the risk of lymph node invasion was directly proportional to PPC and more stratification of the risk of pN1 disease was operated by PSA and BGP. The model allowed the stratification of the patient population in 4 groups and showed that the risk of lymph node invasion progressively increased as the risk group ranked from 1 to 4.
journal_name
Urol Intjournal_title
Urologia internationalisauthors
Porcaro AB,de Luyk N,Corsi P,Sebben M,Tafuri A,Mattevi D,Processali T,Cerruto MA,Brunelli M,Zecchini Antoniolli S,Siracusano S,Artibani Wdoi
10.1159/000458763subject
Has Abstractpub_date
2017-01-01 00:00:00pages
207-214issue
2eissn
0042-1138issn
1423-0399pii
000458763journal_volume
99pub_type
杂志文章abstract::In unilateral kidney disease, it has been suggested that the ipsilateral state could be estimated by measuring contralateral kidney size; thus, a contralateral increase should reflect an ipsilateral impairment and vice versa. This could easily be performed using ultrasound. In our experiments with partial obstruction ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282898
更新日期:1996-01-01 00:00:00
abstract::The spontaneous contractile force of muscle strips isolated from male rabbit urinary bladder dome [detrusor) and base (trigonal muscle) was dose dependently inhibited by isoproterenol, a non-specific beta-adrenoceptor agonist. The relaxant response to 10(-6) M isoproterenol in the detrusor muscle was completely blocke...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281650
更新日期:1990-01-01 00:00:00
abstract::Of 15 patients with primary aldosteronism, 7 had idiopathic adrenal hyperplasia (IHA) and 8 had aldosterone-producing adenoma (APA). In order to determine any renal problems involved in the treatment, the renal clearance of these patients was analyzed and the results compared with those obtained from 12 patients with ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281962
更新日期:1987-01-01 00:00:00
abstract:INTRODUCTION:To identify the risk factors, characteristics and prognosis of patients treated with docetaxel-based chemotherapy for peritoneal carcinomatosis due to metastatic castrate-resistant prostate cancer (mCRPC). METHODS:We retrospectively reviewed our series of mCRPC patients with peritoneal metastases treated ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000354396
更新日期:2014-01-01 00:00:00
abstract::The authors improved the Nélaton catheter with a pair of carbon fiber electrodes as previously published and also improved the Foley catheter with a pair of carbon fiber electrodes which are less painful and easier to use. We also have made efforts how to record the vesical electromyogram (EMG) simultaneously with cys...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280979
更新日期:1984-01-01 00:00:00
abstract::Using C3H/He JCr mice bearing the syngeneic MBT-2 bladder tumor, it was found that cyclophosphamide (CYC 100 mg/kg i.p.) treatment, 1 day before and 2 weeks after surgery, followed by postoperative autologous tumor vaccine immunization can be an effective adjuvant anticancer therapy. The short-term exogeneous addition...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282623
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVES:This meta-analysis was to assess solifenacin and tolterodine in patients with overactive bladder. METHODS:We searched PubMed, the Cochrane Library, EMBASE, CNKI, Wanfang, and ClinicalTrials.gov databases for randomized controlled trials (RCTs). The efficacy endpoint was daily micturition frequency, daily ur...
journal_title:Urologia internationalis
pub_type: 杂志文章,meta分析
doi:10.1159/000497311
更新日期:2019-01-01 00:00:00
abstract:INTRODUCTION:Virtual reality (VR) simulation has been known to shorten learning curves. The aim of this research was to determine whether VR transurethral bladder tumor resection (TURBT) with and without photodynamic diagnostic (PDD) can improve endourological skills in novice and trained endoscopists. MATERIALS AND M...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000328218
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:The last decade has seen the emergence of a variety of supine positions for carrying out percutaneous nephrolithotomy (PCNL). These positions all differ with regard to ease of puncture under image guidance, operative field availability, ability to make and dilate multiple tracts and ease of combining retrogr...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000341430
更新日期:2012-01-01 00:00:00
abstract::We report 2 cases of epidermoid cysts of the testis in Klinefelter's syndrome. The literature is reviewed and the relationship between Klinefelter's syndrome and epidermoid cyst of the testis is discussed. ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282003
更新日期:1987-01-01 00:00:00
abstract:OBJECTIVE:In spite of readily available evidence-based guidelines on urolithiasis treatment, practical applications of treatments vary from country to country, or even within countries. The choice of treatment depends not only on the evidence, but often on general non-medical decision factors such as infrastructure, ex...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000441041
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Fournier's gangrene (FG) is a very aggressive necrotizing fasciitis involving subcutaneous fat and skin of scrotal and perineal regions. Vacuum-assisted closure (VAC) is a well-known method used to treat complex wounds. The authors for the first time enhance a multimodal strategy to treat the FG using VAC, r...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000218532
更新日期:2009-01-01 00:00:00
abstract:INTRODUCTION:Partial unilateral ureteral obstruction (PUUO) is the type of obstruction that is most often encountered in pediatric clinical practice. The majority of our knowledge on PUUO has been derived from experimental studies and the effects of PUUO on the kidney have still been a source of continual investigation...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000111736
更新日期:2008-01-01 00:00:00
abstract:AIMS:To investigate the effect of sildenafil on uroflowmetry values of patients with lower urinary tract symptoms (LUTS) suggestive of benign prostatic enlargement (BPE). METHODS:Thirty-eight consecutive patients and 15 control subjects without voiding symptoms were enrolled in the study. All patients underwent uroflo...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000112611
更新日期:2008-01-01 00:00:00
abstract::We report on the familial occurrence of congenital bulbar urethral stricture in 2 brothers. Embryological mechanisms are briefly discussed and the literature reviewed. ...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000281795
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:To investigate patients' opinions on the degree of pain during shock wave lithotripsy, and the need for analgesics in patients with urinary stone. METHODS:A prospective questionnaire study involving subjective pain assessment during and just after shock wave lithotripsy was performed in consecutive patients ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000082710
更新日期:2005-01-01 00:00:00
abstract::We report the case of a 70-year-old man who received sunitinib treatment for brain metastatic clear cell renal cell carcinoma. After 6 months of treatment, brain MRI showed complete disappearance of two brain metastases. To the best of our knowledge, this is the first reported case of multifocal brain metastases in re...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000251193
更新日期:2009-01-01 00:00:00
abstract:INTRODUCTION:This study assesses the differences in the presentations, complications and metabolic abnormalities of children with renal calyceal microlithiasis (RCM) and overt urolithiasis in different pediatric ages. MATERIALS AND METHODS:A total of 465 children with urolithiasis were investigated retrospectively. Pa...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000441126
更新日期:2016-01-01 00:00:00
abstract::In a 3-year study, silicone rubber prostheses were implanted in 6 minipigs as ureteric replacement. A Dacron velour cuff was applied for the proximal anastomosis and a disc of the same material implanted into the bladder wall to anchor the prosthesis distally. The silicone tube incorporated a metal spiral to prevent k...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280953
更新日期:1984-01-01 00:00:00
abstract::The rate of recurrence after internal urethrotomy a.m. Sachse was studied in a prospective, consecutive, randomized series of 43 patients using short-term (1 day) and long-term (14 days) postoperative catheter treatment. No significant difference was found between the two groups according to voiding interview, flowmet...
journal_title:Urologia internationalis
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000280991
更新日期:1984-01-01 00:00:00
abstract:OBJECTIVE:This randomized controlled study compared a novel transparent urinary tract simulator with the traditional opaque urinary tract simulator as an aid for efficiently teaching urological surgical procedures. METHODS:Senior medical students were tested on their understanding of urological theory before and after...
journal_title:Urologia internationalis
pub_type: 杂志文章,随机对照试验
doi:10.1159/000375129
更新日期:2015-01-01 00:00:00
abstract::We report the first case of aspergillus mycotic aneurysm as a sequel to concomitant prostatic and renal aspergillosis. The patient had undergone left nephrectomy and transurethral resection of prostate for aspergillus infection one year ago. He again presented with LUTS and backache and clinical examination showed vis...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000056561
更新日期:2001-01-01 00:00:00
abstract::From April 1978 to September 1993, the Department of Urology of Giessen Medical School used laser urethrotomy as standard endoscopic treatment in benign urethral strictures. In this period, 900 urethrotomies were performed in 450 patients. The majority of strictures treated were iatrogenic (65%), located in the poster...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282774
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVE:The aim of the present study was to assess the occurrence of ectopic remnants of adrenal cortex tissue encountered in pediatric patients who underwent groin surgical explorations. MATERIALS AND METHODS:We studied 1,862 patients with groin surgical explorations during a period of 12 consecutive years (1995-20...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000151411
更新日期:2008-01-01 00:00:00
abstract::The ability of three compounds, all similar in chemical structure to citric acid, to decrease calcium crystalluria has been measured. The measurements were made in normal human urine at 37 degrees C and compared with the crystal-decreasing power of citric acid when measured in the same way and in the same urine sample...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282875
更新日期:1996-01-01 00:00:00
abstract:OBJECTIVE:The study aimed to document the types of meatal occlusive disease (MOD) in adult males in terms of its clinical presentation, management and prognosis. MATERIAL AND METHODS:Eighty-six adult males with MOD were assessed during the study period. The patients were divided into Group 1, having meatal opening tha...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000446221
更新日期:2016-01-01 00:00:00
abstract::Curative treatment of bladder cancer is limited to superficial tumors (Ta-T2). Advanced stages (T3a + T3b) can be treated only palliatively even when confined to the bladder (N0, M0). Nevertheless the differentiation between curable and incurable tumors is difficult. The classification of patients into the two differe...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281064
更新日期:1985-01-01 00:00:00
abstract::Upper urinary tract dynamics was evaluated using diuresis renography during full and empty reservoir in 14 patients (11 men, 3 women, 13-70 years old) with intestinal urinary reservoir or intestinal bladder augmentation. Types of operation were Mainz pouch urinary diversion 5, Mainz neobladder to urethra, 5, Kock pouc...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282528
更新日期:1993-01-01 00:00:00
abstract:AIM:To examine the hypothesis that the risk of high-grade bladder cancer can be predicted using noninvasively obtained data. PATIENTS AND METHODS:We retrospectively analyzed the database of 431 patients that had transurethral resection of first-time bladder tumors between June 1998 and December 2009. Pre-operative par...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000328635
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVES:To develop risk predictive models of postpartum stress urinary incontinence (SUI) for both primiparous and multiparous women. MATERIALS AND METHODS:From July 2016 to July 2017, 815 singleton pregnant women without incontinence before pregnancy who were 18 years or older and admitted to 2 hospitals in Shenzh...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000508416
更新日期:2020-01-01 00:00:00