Abstract:
:Using C3H/He JCr mice bearing the syngeneic MBT-2 bladder tumor, it was found that cyclophosphamide (CYC 100 mg/kg i.p.) treatment, 1 day before and 2 weeks after surgery, followed by postoperative autologous tumor vaccine immunization can be an effective adjuvant anticancer therapy. The short-term exogeneous addition of low dose Il-2 administration to the protocol provided no further benefit. Suppression of tumor growth was observed in a classical Winn assay when splenocytes were obtained on day 23 from mice receiving this effective adjuvant therapy with surgery on day 8. Splenocytes from tumor-bearing mice (TBM) treated with CYC were augmented in terms of their proliferative response to concanavalin A during the first 2 weeks after CYC treatment. Studies using 3-day TBM established that significant suppression of tumor growth and prolonged survivals were dependent upon CYC treatment being combined with tumor vaccine and/or interleukin-2; single agent treatments were ineffective.
journal_name
Urol Intjournal_title
Urologia internationalisauthors
Tzai TS,Lin JS,Chow NHdoi
10.1159/000282623subject
Has Abstractpub_date
1994-01-01 00:00:00pages
6-11issue
1eissn
0042-1138issn
1423-0399journal_volume
53pub_type
杂志文章abstract::Ischemia, induced by atherosclerosis, is a common cause of disorders in the elderly. Bladder dysfunction in older people may be caused by detrusor ischemia. We compared blood flow to the bladder and detrusor function in vivo and in vitro in young (6-month-old) and aged (24-month-old) male Sprague-Dawley rats. In both ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000030365
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVE:To analyze the correlation between the genotypic and phenotypic patterns of p53 in patients with transitional cell carcinoma (TCC) of the urinary bladder. MATERIALS AND METHODS:Cross-sectional study of 73 patients diagnosed with TCC. DNA was obtained from the tumor tissue to perform polymerase chain reaction...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000109717
更新日期:2007-01-01 00:00:00
abstract::420 patients were treated with transurethral, intravesical electrotherapy to improve the function of paralyzed urinary bladder. Normal conscious micturition control was obtained by 314 patients. This electrotherapy contrasts sharply in method and goal with all implanted pacemakers or inserted electric plugs. Nor does ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000279979
更新日期:1975-01-01 00:00:00
abstract:PURPOSE:The short-term effects of intravesical chemoimmunotherapy with epirubicin and bacillus Calmette-Guérin (BCG) administered repeatedly for prophylaxis of recurrence of superficial bladder cancer (pTa, pT1) were investigated in 24 patients aged a median of 70 years between March 1996 and February 1999, and were co...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000051005
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:This study aimed at comparing the urinary protein levels in calcium stone formers with those of healthy individuals. PATIENTS AND METHODS:From January 2002 until June 2004, 100 calcium stone formers (mean age 38.6 +/- 10.3 years), who had at least two episodes of calcium stone formation, were compared with 1...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000090882
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:Elevated serum C-reactive protein (CRP) level has been demonstrated to predict poorer survival of both localized and metastatic renal cell carcinoma. However, the prognostic value of intratumoral CRP expression has not been sufficiently studied. PATIENTS AND METHODS:In the present study, the expression of C...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000353401
更新日期:2014-01-01 00:00:00
abstract::A case of entrapped nephrostomy tube in a 61-year-old woman who underwent percutaneous nephrolithotomy and subsequent multiple ESWL for a left staghorn stone is presented. A nephrostomy track was created alongside the Malecot catheter and the overgrown tissue which was bridging the wings of the tube was incised with a...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000075973
更新日期:2004-01-01 00:00:00
abstract::The bladder pressure necessary to cause vesicoureteral reflux (VUR) was measured in 16 female rats. Under general anesthesia, the ureters were exposed via an abdominal incision and a pressure catheter was placed near the ureterovesical junction. Values of bladder distension and bladder pressure increase to cause VUR w...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281195
更新日期:1986-01-01 00:00:00
abstract:INTRODUCTION:Open radical cystectomy (ORC) is currently the standard treatment for muscle-invasive bladder cancer (MIBC) without metastasis, while many patients with MIBC are not always appropriate candidates due to multiple comorbidities. To evaluate the bladder-preservation strategy, we compared the results with thos...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000477912
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the safety and feasibility of percutaneous tract dilation by the one-stage method in preschool children. METHODS:Between April 2009 and February 2013, all preschool (<6 years) children who were candidates for percutaneous nephrolithotomy were enrolled in this prospective study. Patients were rand...
journal_title:Urologia internationalis
pub_type: 杂志文章,随机对照试验
doi:10.1159/000356327
更新日期:2014-01-01 00:00:00
abstract::Adherence of human prostate carcinoma (PC 3, DU 145), bladder (647 V, J 82) carcinoma and melanoma (RPMI-8252) cell lines to plastic and bovine endothelial monolayers (BEM) was tested in the presence of 0.5, 1, 5, 10, 20 IU of low-molecular-weight heparin (LMWH), unfractionated heparin (UFH) or saline as a control. Cu...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282848
更新日期:1996-01-01 00:00:00
abstract::We report on the familial occurrence of congenital bulbar urethral stricture in 2 brothers. Embryological mechanisms are briefly discussed and the literature reviewed. ...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000281795
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:The aim of this prospective study was to examine the ability of the Snap-Gauge band to differentiate organic from psychogenic erectile dysfunction (ED). PATIENTS AND METHODS:Nocturnal penile tumescence testing was performed on 12 patients using a Snap-Gauge band and RigiScan Plus. A total of 29 nightly exami...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000071103
更新日期:2003-01-01 00:00:00
abstract:INTRODUCTION:We reviewed our experiences in performing cytoreductive metastatectomy before initiating systemic immunochemotherapy and tried to investigate potential prognostic factors for such an approach. PATIENTS AND METHODS:A retrospective analysis of 57 patients who received interleukin-2, interferon-alpha, and 5-...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000091630
更新日期:2006-01-01 00:00:00
abstract::A case of malignant peripheral nerve sheath tumor of the bladder in a 57-year-old man with multiple neurofibromatosis type 1 is presented. The patient had a recent history of a transurethrally resected bladder ganglioneuroma. A probable histogenetic association between these two extremely rare neoplasms is proposed. ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000065568
更新日期:2002-01-01 00:00:00
abstract::We report a case of clitoral hypertrophy of unknown origin. A 3-year-old girl showed clitoral hypertrophy at birth. Biochemical analysis of peripheral blood and endocrinological examinations were normal. Other virilizing symptoms were not recognized. Clitoroplasty was carried out, and the clitoris has not enlarged 20 ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000030385
更新日期:1999-01-01 00:00:00
abstract:PURPOSE:The study aimed to investigate clinical factors associating with occult lymph node micrometastases (pN1 disease) in a contemporary cohort of organ-confined prostate cancer (PCA) patients staged as cN0. MATERIALS AND METHODS:The study evaluated 184 consecutive patients. Associations of clinical factors with pN1...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000458763
更新日期:2017-01-01 00:00:00
abstract:INTRODUCTION:In order to accurately assess the extent of chronic pelvic pain syndrome (CPPS) and to objectively measure symptoms for natural history studies and to assess the outcome parameters for clinical trials, the National Institutes of Health (NIH) Chronic Prostatitis Collaborative Research Network developed and ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000094814
更新日期:2006-01-01 00:00:00
abstract::Laparoscopic partial nephrectomy (LPN) is increasingly becoming a definitive therapeutic option for the treatment of small (less than 4 cm) and select moderate-sized (less than 7 cm) renal tumors. Postoperative hemorrhage and urine leak are the most pertinent complications after nephron-sparing surgery, open or laparo...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000331905
更新日期:2011-01-01 00:00:00
abstract::A new device for the simultaneous in vivo measurement of pressure and developed force in the ureter is introduced. The 5-French catheter was cystoscopically inserted into the ureters of 12 dogs under anesthesia. The forms of the peristaltic waves for pressure and force show considerable differences. A basal force anal...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282119
更新日期:1991-01-01 00:00:00
abstract:INTRODUCTION:Augmentation cystoplasty is an effective approach to the detrusor hyperreflexia which is refractory to conservative treatment. Sporadic data have been published in patients with progressive diseases such as multiple sclerosis (MS). MATERIALS AND METHODS:Augmentation ileocystoplasty (Goodwin 'cup-patch') w...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000067708
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:To investigate the reliability of the physician-assisted International Index of Erectile Function (IIEF). PATIENTS AND METHODS:374 patients who applied to our clinic with erectile dysfunction problems were asked to complete the IIEF questionnaire; 225 patients who visited the clinic again within 1-3 days com...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000335432
更新日期:2012-01-01 00:00:00
abstract:INTRODUCTION:Micropapillary carcinoma (MPC) of the bladder is a rare and aggressive histologic variant of urothelial carcinoma (UC). At the time of presentation, most MPC are muscle invasive with frequent vascular invasion (VI). Our series explores protein expression of markers known to be indicators of poor clinical o...
journal_title:Urologia internationalis
pub_type: 杂志文章,多中心研究
doi:10.1159/000209364
更新日期:2009-01-01 00:00:00
abstract::Modern LDR brachytherapy has drastically reduced rectal toxicity and decreased the occurrence of rectourethral fistulas to <0.5% of patients. Therefore, symptoms of late-onset sequelae are often ignored initially. These fistulas cause severe patient morbidity and require interdisciplinary treatment. We report on the o...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000209374
更新日期:2009-01-01 00:00:00
abstract::The overnight (12 h) urinary excretion of glycosaminoglycans, citrate, magnesium, calcium and uric acid were measured in 82 normal subjects and 63 outpatients who had formed at least one urinary stone. No significant difference could be found between the two groups of unselected subjects with respect to any of the uri...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281493
更新日期:1989-01-01 00:00:00
abstract:OBJECTIVE:Laparoscopic nephroureterectomy (LNU) offers a superior morbidity profile compared with open nephroureterectomy (ONU) in treating upper urinary tract urothelial cell carcinoma. Evidence of oncological equivalence between LNU and ONU is limited. We compare operative and oncological outcomes for LNU and ONU usi...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000364833
更新日期:2015-01-01 00:00:00
abstract::The first case of barium granuloma involving urinary bladder is reported. Surgical removal was the treatment of choice. Histological diagnosis was foreign body granuloma with xanthomatous inflammation. The foreign body was identified as barium by analytical electron microscopy. ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281516
更新日期:1989-01-01 00:00:00
abstract::Metastatic renal cell carcinoma (mRCC) is a difficult to treat malignancy and currently Sunitinib is a standard of care first-line therapy. A new metastasis during the treatment is considered a sign of drug failure and alternative therapeutic methods should be tried. Here, we report 2 cases of newly diagnosed isolated...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000321908
更新日期:2011-01-01 00:00:00
abstract:AIM:To evaluate outcomes of laparoscopic adrenalectomy (LA) and laparoendoscopic single-site surgery (LESS) for adrenal masses in the light of changing laparoscopic surgical techniques. MATERIALS AND METHODS:Seventy-three patients were analyzed retrospectively. There were 2 groups; group 1 included patients who had co...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000351959
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:To establish the bacterial flora of the perineum before and after antiseptic preparation in male urology patients. PATIENTS/METHODS:Adult male patients undergoing cystoscopic procedures were studied. Three sets of swab specimens, labelled A, B and C, were taken from the perineum in the theatre. Specimen A wa...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000167837
更新日期:2008-01-01 00:00:00