Abstract:
BACKGROUND:Elevated serum C-reactive protein (CRP) level has been demonstrated to predict poorer survival of both localized and metastatic renal cell carcinoma. However, the prognostic value of intratumoral CRP expression has not been sufficiently studied. PATIENTS AND METHODS:In the present study, the expression of CRP was evaluated with immunohistochemical analysis in 127 patients who had undergone curative surgery for clear cell renal cell carcinoma. CRP staining was scored using the immunoreactivity score. An immunoreactivity score of 4 (median value) or lower was considered negative, a score higher than 4 was considered positive CRP expression. RESULTS:Univariate analysis revealed that Fuhrman grade, necrosis, vascular invasion, TNM stage and CRP expression were associated with tumor-specific survival. Multivariate analysis using the Cox proportional hazards regression method revealed only TNM stage as an independent predictor of tumor-specific survival (p = 0.001). A trend towards significance (p = 0.066) was observed with CRP expression, but it did not reach significance. Patients with a positive CRP score were 3.46 times more likely to die than patients with a negative CRP score. CONCLUSION:Our results suggest that the assessment of intratumoral CRP expression may be a useful tool for predicting the prognosis in patients with clear cell renal cell carcinoma.
journal_name
Urol Intjournal_title
Urologia internationalisauthors
Can C,Acikalin MF,Ozen A,Dundar Edoi
10.1159/000353401subject
Has Abstractpub_date
2014-01-01 00:00:00pages
270-5issue
3eissn
0042-1138issn
1423-0399pii
000353401journal_volume
92pub_type
杂志文章abstract::We report 2 cases of epidermoid cysts of the testis in Klinefelter's syndrome. The literature is reviewed and the relationship between Klinefelter's syndrome and epidermoid cyst of the testis is discussed. ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282003
更新日期:1987-01-01 00:00:00
abstract:OBJECTIVES:To investigate whether congenital renal vein anomalies are involved in the etiology of hematuria by analyzing abdominal multidetector computed tomography (MDCT) results. METHODS:Six hundred and eighty patients undergoing MDCT for various abdominal pathologies in whom possible causes of hematuria were exclud...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000365664
更新日期:2015-01-01 00:00:00
abstract::35 women, referred for simple total hysterectomy, were evaluated pre- and postoperatively for bladder suspension and urodynamic changes. Although all patients denied urological problems, more than half of the patients had some degree of stress and/or urge incontinence. 40% had radiological signs of bladder suspension ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281085
更新日期:1985-01-01 00:00:00
abstract::A case of entrapped nephrostomy tube in a 61-year-old woman who underwent percutaneous nephrolithotomy and subsequent multiple ESWL for a left staghorn stone is presented. A nephrostomy track was created alongside the Malecot catheter and the overgrown tissue which was bridging the wings of the tube was incised with a...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000075973
更新日期:2004-01-01 00:00:00
abstract::Splenic metastases of solid tumors are exceptional. We report the first case of an isolated splenic metastasis from prostate carcinoma, 5 years after radical prostatectomy. The splenic tumor was revealed by a pain and progressive increase in the serum prostate-specific antigen (PSA) level. Histology of the spleen show...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000096942
更新日期:2007-01-01 00:00:00
abstract:INTRODUCTION:Robot-assisted bladder diverticulectomy (RABD) through a technique for easier identification of diverticulum along with concomitant management of bladder outlet obstruction (BOO) utilizing a combination of transurethral prostatectomy (TUR-P) and photoselective vaporization of prostate (PVP) is presented. ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000443799
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:Activated nuclear factor-ĸB is associated with the pathogenesis of numerous malignancies, including renal cell carcinoma (RCC). This study aimed to clarify the influence of a common insertion/deletion polymorphism (-94 ins/del ATTG, rs28362491) in the NFKB1 promoter on RCC susceptibility. METHODS:We genotype...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000345630
更新日期:2013-01-01 00:00:00
abstract::Urinoma as a presenting sign of carcinoma of the bladder, as occurred in this case, is rare. Aspiration of the cystic mass under sonography and chemistry of the fluid confirmed the diagnosis. The inferior extension of the urinoma on CT scan confirmed the gradual fading of Gerota's fascia into the retroperitoneum. Abdo...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281044
更新日期:1985-01-01 00:00:00
abstract:INTRODUCTION:Etiology of serum anti-p53 antibodies in bladder cancer patients is still unknown. In this study we evaluated the relationship between serum anti-p53 antibodies and microvessel density in bladder cancer patients. MATERIALS AND METHODS:Seventy-six patients with transitional cell carcinoma of the urinary bl...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000080831
更新日期:2004-01-01 00:00:00
abstract::On reviewing the literature most authors were found to have used needle electrodes for recording muscle potentials of pelvic floor muscles. We used for the first time a vaginal tampon electrode to record potentials of musculus levator ani in females and the same electrode to record potentials of the external anal sphi...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000280033
更新日期:1976-01-01 00:00:00
abstract::Regenerative medicine, tissue engineering and biomedical research give hope to many patients who need bio-implants. Tissue engineering applications have already been developed based on bioreactors. Physiological ureter implants, however, do not still function sufficiently, as they represent tubular hollow structures w...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000368419
更新日期:2015-01-01 00:00:00
abstract::We report a rare case of Budd-Chiari syndrome (BCS) as a postoperative complication after bilateral nephrectomy in a kidney transplant recipient with polycystic liver and kidneys. Contrast-enhanced computed tomography of the abdomen showed a narrowed inferior vena cava, compressed by the polycystic liver that moved do...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000504514
更新日期:2020-01-01 00:00:00
abstract::A 50-year-old man with hemophilia A presented with recurrent hematuria due to renal stone disease. He was receiving approximately 50,000 units of recombinant factor (rF) VIII concentrate every year due to hematuria. Between 1996 and 2002, his serum creatinine level increased from 0.7 to 1.2 ng/ml. In an effort to reso...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000100846
更新日期:2007-01-01 00:00:00
abstract:AIM:The aim of this study was to compare the postoperative analgesic effectiveness of the 2 block types. We also aimed to evaluate the effect of these block types on the postoperative complications and parental satisfaction. MATERIALS AND METHODS:This prospective observational study was conducted between April and Jul...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000509173
更新日期:2020-01-01 00:00:00
abstract::A case of spontaneous, partial, unilateral thrombosis of the corpus cavernosum is described. A 35-year-old white male presented with a painful mass in the perineum without priapism. Diagnostic evaluation with sonography and magnetic resonance imaging revealed a thrombosis in the left posterior corporal body. Treatment...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000030246
更新日期:1998-01-01 00:00:00
abstract::Prostate volume in multiparametric MRI (mpMRI) is of clinical importance. For 3-Tesla mpMRI without endorectal coil, there is no distinctive standard for volume calculation. We tested the accuracy of the ellipsoid formula with planimetric volume measurements as reference and investigated the correlation of gland volum...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000448593
更新日期:2017-01-01 00:00:00
abstract::The overnight (12 h) urinary excretion of glycosaminoglycans, citrate, magnesium, calcium and uric acid were measured in 82 normal subjects and 63 outpatients who had formed at least one urinary stone. No significant difference could be found between the two groups of unselected subjects with respect to any of the uri...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281493
更新日期:1989-01-01 00:00:00
abstract::The present study was undertaken to analyze the changes in neuroendocrine cells of the human prostate induced by neoplasms and the effect of hormonal treatment. Samples of human prostate (n = 47) were obtained during surgery or removal of organs for transplantation. The cases analyzed represent normal prostates (n = 4...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000283051
更新日期:1997-01-01 00:00:00
abstract::The bladder pressure necessary to cause vesicoureteral reflux (VUR) was measured in 16 female rats. Under general anesthesia, the ureters were exposed via an abdominal incision and a pressure catheter was placed near the ureterovesical junction. Values of bladder distension and bladder pressure increase to cause VUR w...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281195
更新日期:1986-01-01 00:00:00
abstract::An unusual case of metastatic carcinoma of prostate, which presented as a huge abdominal mass and responded extremely well to endocrine therapy, is presented. The literature is reviewed. ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281205
更新日期:1986-01-01 00:00:00
abstract::A rare case of abscess of the corpus cavernosum is described. Culture of the abscess yielded beta-hemolytic streptococcus. Ultrasound scan and cavernosography confirmed the physical examination findings of involvement of the corpus cavernosum. The patient was treated successfully by percutaneous ultrasound-guided aspi...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282373
更新日期:1992-01-01 00:00:00
abstract::The alpha-adrenergic innervation of the functional urethra is a well-known fact, while beta-adrenergic influence is rather unknown until now. We studied the influence of beta-stimulating and beta-blocking agents on the human urethra by the urethral pressure profile (UPP). A decrease of the UPP under orciprenaline sulf...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280224
更新日期:1978-01-01 00:00:00
abstract::A technical evaluation of the Exeter recording nappy has been carried out with particular reference to (a) linearity, (b) reproducibility of calibration, (c) the effect of variation in the position of moistened zones produced by consecutive leakages and (d) the effect of variation in the electrical conductivity of the...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280034
更新日期:1976-01-01 00:00:00
abstract::We report on a unique-sized large leiomyoma of the bladder wall in a male patient. After open surgical intervention all symptoms resolved spontaneously and no relapse occurred within a 3-year follow-up period. In conclusion, for symptomatic leiomyoma of the bladder surgical intervention should be considered as an earl...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000030317
更新日期:1998-01-01 00:00:00
abstract::Multiple oral doses of alpha-difluoromethyl-ornithine (alpha-DFMO), 18-24 g/day for up to 2 months, were administered to 2 patients with invasive and metastatic carcinoma of the bladder and to 3 patients with metastatic renal cancer in an open study. The moderate antigrowth effect of alpha-DFMO in these patients was c...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280403
更新日期:1981-01-01 00:00:00
abstract::A medium that had been conditioned by PC-3 cells stimulated the calcification of a human osteoblastic cell line, Tak-10, in a nonmitogenic culture. The calcification of the osteoblasts was stimulated maximally at a 25% concentration of the conditioned medium. Calcification activity was markedly enhanced by the additio...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282291
更新日期:1992-01-01 00:00:00
abstract::Controversies abound in relation to the treatment of every stage of prostate cancer and its natural history. We critically evaluate the controversies and information that exist. An ongoing autopsy project at Wayne State University aims to: define the prevalence of incidental cancer in subjects between 20 and 70 years ...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000282860
更新日期:1996-01-01 00:00:00
abstract::A partial urethral obstruction was induced in female rats. After 6 weeks, detrusor weight had increased eightfold and collagen concentration had decreased to about 40% compared to controls. Due to the weight gain, the total amount of detrusor collagen had increased more than threefold. Removal of the obstruction led t...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282230
更新日期:1991-01-01 00:00:00
abstract::We present a new modified in vitro culture assay for primary human renal cell carcinoma similar to the 'soft agar clonogenic assay'. However, the carrying out and expense of metrology are more simplified, allowing tumor-specific chemotherapeutic drug sensitivity testing under easier conditions. Twelve different sample...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281178
更新日期:1986-01-01 00:00:00
abstract::We examined a 46-year-old male patient with idiopathic myelofibrosis diagnosed 28 months earlier. After chemotherapy and irradiation, CT showed nonnodular, soft tissue masses in the renal hilum, pelvicaliceal system, perirenal and periureteral spaces. Ultrasound-guided biopsy showed extramedullary hematopoiesis (EMH)....
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000087809
更新日期:2005-01-01 00:00:00