Issues on early diagnosis and treatment of localized prostate cancer.

Abstract:

:Controversies abound in relation to the treatment of every stage of prostate cancer and its natural history. We critically evaluate the controversies and information that exist. An ongoing autopsy project at Wayne State University aims to: define the prevalence of incidental cancer in subjects between 20 and 70 years of age; study the potential difference between Caucasians and Blacks; and to analyze other associated histological lesions such as prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia. Initial results note that there was only a weak correlation between high-grade PIN and incidental carcinoma, both lesions started to present at an early age with a progressive increase after the seventh decade, and there was no racial difference observed among Caucasians and African-American males. These results pose several questions which need further explanation. Most studies use digitorectal examination, transrectal 7-MHz ultrasonography and prostate-specific antigen for the early diagnosis of prostate cancer, we attempt to determine the best and most economical combination presently available. In discussing the therapeutic options for patients with localized prostate cancer, we review our personal experience with surgery and radiotherapy.

journal_name

Urol Int

journal_title

Urologia internationalis

authors

Pontes JE

doi

10.1159/000282860

subject

Has Abstract

pub_date

1996-01-01 00:00:00

pages

1-5

eissn

0042-1138

issn

1423-0399

journal_volume

56 Suppl 1

pub_type

杂志文章,评审
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  • The impact of prior TURP on radical prostatectomy surgical margins: a multicenter analysis.

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  • Bladder carcinoma in patients less than 40 years of age.

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    doi:10.1159/000477912

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  • Plasmacytoma of the testis.

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    更新日期:1995-01-01 00:00:00

  • Cytogenetic study in 102 infertile men.

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    authors: Gündüz G,Lüleci G,Baykara M

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  • Recurrent, Giant Renal Angiomyolipoma Treated with Selective Arterial Embolization: A Case Report.

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  • Mini-invasive management of a rare complication of percutaneous stone treatment: entrapped nephrostomy tube.

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  • An Open-Label Pilot Study of Metformin as a Concomitant Therapy on Patients with Prostate Cancer Undergoing Androgen Deprivation Treatment.

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    journal_title:Urologia internationalis

    pub_type: 杂志文章,随机对照试验

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  • The Relationship between Acidic Urinary pH and Overactive Bladder; Alkalization of Urine Improves the Symptoms of Overactive Bladder.

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  • Pathological changes of traumatic dislocated testis.

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    journal_title:Urologia internationalis

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    doi:10.1159/000282830

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  • Is Endoscopic Vasectomy Just a Dream: An ex vivo Study on Feasibility and Reliability of Endoluminal Occlusion of Porcine Vas Deferens.

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    doi:10.1159/000144061

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    pub_type: 杂志文章

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    更新日期:1995-01-01 00:00:00

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    pub_type: 杂志文章

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    pub_type: 杂志文章

    doi:10.1159/000441041

    authors: Durner L,Bach C,El Howairis Mel F,Hakenberg OW,Buchholz N

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