Pressure evaluation of the antireflux ability of the rat ureterovesical junction.

Abstract:

:The bladder pressure necessary to cause vesicoureteral reflux (VUR) was measured in 16 female rats. Under general anesthesia, the ureters were exposed via an abdominal incision and a pressure catheter was placed near the ureterovesical junction. Values of bladder distension and bladder pressure increase to cause VUR were obtained by injecting isotonic saline in one ureter until VUR in the opposite ureter was detected as a sudden pressure increase. After 5 min the same procedure was done on the contralateral side. This procedure was repeated eight times in each rat with a 15-min intermission. The bladder pressure at which VUR occurred was measured through a ureteral catheter. Two groups were studied: G1, control, and G2, administration of intravenous metoclopramide (0.007 mg/100 g body weight) four times.

journal_name

Urol Int

journal_title

Urologia internationalis

authors

Vercesi LA,Constantinou CE

doi

10.1159/000281195

subject

Has Abstract

pub_date

1986-01-01 00:00:00

pages

192-5

issue

3

eissn

0042-1138

issn

1423-0399

journal_volume

41

pub_type

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