Abstract:
INTRODUCTION:The percentage of positive prostate biopsy cores (%PBC) has been shown to be a prognostic factor in localized prostate cancer. We hypothesized that it would predict time to hormonal independence and survival in prostate cancer patients treated with androgen deprivation therapy (ADT). PATIENTS AND METHODS:We used clinical data from 403 men treated with ADT between 1980 and 1999 and focused on a subgroup of 220 patients treated with GnRH analogue. %PBC was defined as the number of positive biopsy cores multiplied by 100 and divided by the total number of biopsy cores. RESULTS:Median %PBC was 83.3% (16.7-100%). Mean follow-up was 57.4 months. Survival at 5 years in men with 83.3% PBC or less was 62.3, 89.1 and 82.6% for recurrence-free, specific and overall survival, respectively, significantly better than that of men with a %PBC of more than 83.3% (32.2, 74.7 and 67.7%, respectively; p < 0.004). Among the factors available in the pretreatment setting, namely age, clinical stage, PSA, Gleason score, bone scan and %PBC, the latter was independently associated with survival in multivariate analysis. CONCLUSIONS:%PBC may improve the ability to predict time to hormonal resistance and survival in patients treated with ADT for prostate cancer. This finding warrants further investigation.
journal_name
Urol Intjournal_title
Urologia internationalisauthors
Normand G,Celhay O,Briffaux R,Pirès C,Doré B,Fromont G,Irani Jdoi
10.1159/000230017subject
Has Abstractpub_date
2009-01-01 00:00:00pages
160-5issue
2eissn
0042-1138issn
1423-0399pii
000230017journal_volume
83pub_type
杂志文章abstract::Vesicovaginal fistula (VVF) is a quite rare complication of gynecological surgery. The first attempt to repair the fistulous tract offers the best opportunity for cure. We report the successful repair of VVF in 2 patients using a combined anterior vaginal approach and porcine dermal collagen grafting as interposition ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000176038
更新日期:2009-01-01 00:00:00
abstract::The present study was undertaken to analyze the changes in neuroendocrine cells of the human prostate induced by neoplasms and the effect of hormonal treatment. Samples of human prostate (n = 47) were obtained during surgery or removal of organs for transplantation. The cases analyzed represent normal prostates (n = 4...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000283051
更新日期:1997-01-01 00:00:00
abstract::The intracavernosal pressure changes induced by 3 vasodilating drugs, diazoxide, glyceryltrinitrate and verapamil were investigated during autologous extracorporeal penile blood perfusion in an experimental rabbit model. In order to separate the arterial and venous components the experiments were performed with both i...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282454
更新日期:1993-01-01 00:00:00
abstract::A 50-year-old man with hemophilia A presented with recurrent hematuria due to renal stone disease. He was receiving approximately 50,000 units of recombinant factor (rF) VIII concentrate every year due to hematuria. Between 1996 and 2002, his serum creatinine level increased from 0.7 to 1.2 ng/ml. In an effort to reso...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000100846
更新日期:2007-01-01 00:00:00
abstract:AIM:Since DNA damage-related apoptosis is raising concerns regarding abnormal spermatogenesis, we investigated the changes in γ-H2AX during testicular germ cell apoptotic responses in the varicocele model. MATERIALS AND METHODS:Varicocele was induced by partial ligation of the left renal vein and animals were sacrific...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000316356
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVES:To assess the role of color Doppler flow imaging (CDFI) in the evaluation of Chinese patients with erectile dysfunction (ED) and to explore the association between penile rigidity and hemodynamic parameters of CDFI. METHODS:Totally 74 ED patients with an age range of 22-69 (median age 47) were included in o...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000127350
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Open radical cystectomy (ORC) is the gold standard of treatment for muscle-invasive bladder cancer. Laparoscopic radical cystectomy (LRC) has emerged to provide an alternative. METHODS:Between 2006 and 2012, 155 patients who underwent LRC or ORC were compared (mean follow-up 53 months). RESULTS:The ORC gro...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000350237
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:The bladder is the most common affected site in urinary tract endometriosis, being diagnosed during gynecologic follow-up. The surgical urological treatment might lead to good results. STUDY OBJECTIVE:To define the state of the art in the diagnosis and treatment of bladder endometriosis. METHODS:We perform...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000339519
更新日期:2012-01-01 00:00:00
abstract::Urethral diverticula are pouches opening into the urethral canal that may be either acquired or congenital. Diverticula of the female urethra are fairly common. However, diverticula of the male urethra are relatively uncommon abnormalities. Clinical manifestation is frequently described with irritative and/or obstruct...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000346321
更新日期:2013-01-01 00:00:00
abstract:PURPOSE:The purpose of this study was to determine whether periurethral injection of allogenic mesenchymal stem cells (MSCs) could increase the leak point pressure (LPP) in a rat model of stress urinary incontinence. MATERIALS AND METHODS:Female Sprague-Dawley rats (230-240 g, n = 30) were divided into 3 groups: sham ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000317322
更新日期:2011-01-01 00:00:00
abstract:INTRODUCTION:To demonstrate the relationship between testicular microlithiasis and testicular tumor development. PATIENTS AND METHODS:Between January 1996 and March 2004, bilateral testicular microlithiasis was found in 40 of the 5,263 patients who underwent scrotal ultrasonography yielding a prevalence of 0.76%. Of t...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000083279
更新日期:2005-01-01 00:00:00
abstract:AIM:To evaluate the efficacy of a new sclerotization technique with pure ethanol in the treatment of symptomatic renal cysts. PATIENTS AND METHODS:Fourteen patients having renal cysts with a meant diameter of 10 (range 5-15) cm were treated. Our technique includes: ultrasound-guided percutaneous puncture with an 18-ga...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000071846
更新日期:2003-01-01 00:00:00
abstract::Two patients treated with chronic dialysis and renal transplantation developed acute hemorrhage from a native kidney. Bilateral native nephrectomy demonstrated acquired cystic disease and adenocarcinoma in each of the four kidneys. The etiology of acquired cystic kidney disease (ACKD) is unclear and its incidence incr...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000030222
更新日期:1998-01-01 00:00:00
abstract::To evaluate the fragility of Ca-oxalate monohydrate stones in terms of high energy shock wave effectivity, we measured the glycosaminoglycan (GAG) content of the organic stone matrix of 35 patients who had undergone extracorporeal shock wave lithotripsy (ESWL) treatment for renal pelvic stones. The patients were class...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282944
更新日期:1997-01-01 00:00:00
abstract:AIMS:To investigate the effect of sildenafil on uroflowmetry values of patients with lower urinary tract symptoms (LUTS) suggestive of benign prostatic enlargement (BPE). METHODS:Thirty-eight consecutive patients and 15 control subjects without voiding symptoms were enrolled in the study. All patients underwent uroflo...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000112611
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:The flexible ureterorenoscope (URS) and associated devices have developed rapidly. However, despite its therapeutic benefits, URS may be associated with some complications. To the best of our knowledge, there are no studies discussing the complications of flexURS during the learning curve. METHODS:A retrosp...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000368617
更新日期:2015-01-01 00:00:00
abstract::We studied the impact of antireflux surgery on bladder compliance, which was an important clinical parameter in terms of urinary incontinence and upper tract deterioration, in 20 myelodysplastics (group A). For control groups, 31 myelodysplastic children with or without reflux who were conservatively treated (group B)...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282253
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVES:To introduce our modified retroperitoneoscopic living-donor nephrectomy (RPLDN) techniques and estimate the learning curve. METHODS:We retrospectively evaluated 121 consecutive donors who underwent modified RPLDN performed by a single surgeon. While the surgeon controlled the renal vessels, one hand was ins...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000493765
更新日期:2018-01-01 00:00:00
abstract::By transforming uroflowmetrograms from curves of flow rate versus time into curves of flow rate versus instantaneous bladder volume, additional information about the variation of the flow rate during voiding is obtained. These curves show that, within a certain volume range, the maximum flow rate is more or less indep...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280157
更新日期:1977-01-01 00:00:00
abstract::We report the first case of aspergillus mycotic aneurysm as a sequel to concomitant prostatic and renal aspergillosis. The patient had undergone left nephrectomy and transurethral resection of prostate for aspergillus infection one year ago. He again presented with LUTS and backache and clinical examination showed vis...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000056561
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:In spite of readily available evidence-based guidelines on urolithiasis treatment, practical applications of treatments vary from country to country, or even within countries. The choice of treatment depends not only on the evidence, but often on general non-medical decision factors such as infrastructure, ex...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000441041
更新日期:2016-01-01 00:00:00
abstract::Transrectal ultrasonography was performed in 46 patients with hemospermia. Abnormal findings in the prostate and seminal vesicles, including prostatic stones, benign prostatic hyperplasia, prostatitis, and dilatation and calculi of the seminal vesicles, were observed in 34 patients (73.9%). However, no malignant lesio...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282655
更新日期:1994-01-01 00:00:00
abstract::Between January 1985 and October 1991, 54 patients with calculi in a solitary kidney were treated by ESWL using the Dornier HM-3 lithotriptor. The mean age of the patients was 53.9 years (range 24-77 years). In 51.9% of the cases the stones measured > 1 cm in diameter, in 42.6% between 0.4 and 1 cm, and in 5.5% < 0.4 ...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000282591
更新日期:1994-01-01 00:00:00
abstract::At the Institute of Urology, University of Padova, 125 patients with multifocal superficial bladder cancer underwent treatment with intravesical Mitomycin C (MMC; 1 weekly instillation of 40 mg for 8 consecutive weeks) between January 1982 and December 1988. Eighty-four patients had multifocal papillary tumors (stages...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282320
更新日期:1992-01-01 00:00:00
abstract:INTRODUCTION:We aimed to evaluate the effects of hyperbaric oxygen therapy (HBOT) on erectile function in patients who had no cavernosal or urethral injury by using International Index of Erectile Function (IIEF) questionnaire. MATERIALS AND METHODS:The male patients who were treated by HBOT for several diseases betwe...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000490356
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:The aim of this work was to verify the tolerability and the preliminary clinical results of intensive intravesical instillations of a mitomycin C (MMC) regimen. PATIENTS AND METHODS:From September 2007 to November 2009, 40 consecutive evaluable patients with pathologically confirmed intermediate-risk non-mus...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000315492
更新日期:2010-01-01 00:00:00
abstract::Primary penile carcinoma is one of the rarest male genital tract tumors. We rarely encounter this malignancy in Turkey because circumcision is routinely performed as a part of the Islamic tradition. Despite the medical paradox that the penis is rarely affected by metastases, approximately 300 cases have been reported ...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000090872
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE:To investigate the diagnostic value of the nuclear matrix protein 22 (NMP22) test in comparison to urine cytology for the detection of upper tract urothelial carcinoma. PATIENTS AND METHODS:Patients with transitional cell carcinoma of the upper urinary tract (n = 34) and patients with renal calculosis (n = 2...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000330246
更新日期:2011-01-01 00:00:00
abstract::Adenosine triphosphate (ATP) and adenosine diphosphate (ADP) have been correlated with traditional semen parameters such as forward motility and sperm count. ATP and ADP were determined by a bioluminescence assay using the luciferin-luciferase reaction. Short boiling of the ejaculate was performed to inactivate phosph...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282361
更新日期:1992-01-01 00:00:00
abstract:INTRODUCTION:We aimed to evaluate the predictive factors in a holistic manner for ureterorenoscopy (URS) outcomes in proximal ureteral stones by a multicenter study. MATERIALS AND METHODS:The data of patients who underwent URS for proximal ureteral stones between the years 2015 and 2018 in eight centers were recorded ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000504790
更新日期:2020-01-01 00:00:00