Late recurrence of a prostatic adenocarcinoma as a solitary splenic metastasis.

Abstract:

:Splenic metastases of solid tumors are exceptional. We report the first case of an isolated splenic metastasis from prostate carcinoma, 5 years after radical prostatectomy. The splenic tumor was revealed by a pain and progressive increase in the serum prostate-specific antigen (PSA) level. Histology of the spleen showed an adenocarcinoma immunostained with cytokeratin and PSA markers. The patient remained asymptomatic and his serum PSA level was within normal limits 17 months after the splenectomy. This case suggests that splenic metastasis might be the result of the growth of an early blood-borne micrometastasis within the spleen after a period of clinical latency.

journal_name

Urol Int

journal_title

Urologia internationalis

authors

Compérat E,Azzouzi AR,Chartier-Kastler E,Ménégaux F,Capron F,Richard F,Charlotte F

doi

10.1159/000096942

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

86-8

issue

1

eissn

0042-1138

issn

1423-0399

pii

000096942

journal_volume

78

pub_type

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