Rheumatoid factors.

abstract：:Food allergy has a dramatic impact on a child's (and their family's) quality of life and places a major financial burden on the community. It has been hypothesized that the increase in food allergy may relate to the concordant rise in prevalence of vitamin D insufficiency. More recently a second hypothesis has implica...

journal_title：Clinical biochemistry

authors： Zakariaeeabkoo R,Allen KJ,Koplin JJ,Vuillermin P,Greaves RF

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVES:Define performance characteristics of the Stratus CS cardiac troponin I (cTnI) assay in routine practice. METHODS:Imprecision at low cTnI values was assessed according to NCCLS EP5-A. Linearity was assessed by regression analysis; the reference interval was determined in 345 healthy individuals. Minimum det...

journal_title：Clinical biochemistry

authors： Christenson RH,Cervelli DR,Bauer RS,Gordon M

更新日期：2004-08-01 00:00:00

abstract：:Iodine deficiency (ID) is associated with increased prevalence of goiter, increased risk for neurodevelopmental disorders, and is the world's leading cause of intellectual deficits. Iodine nutritional status of a population is assessed by measurements of urinary iodine concentrations which are also used to define, ind...

journal_title：Clinical biochemistry

authors： Soldin OP

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVES:The aims of the study were to test the susceptibility of THP-1 macrophages to develop oxidative stress and to deploy antioxidant defense mechanisms that insure the balance between the pro- and antioxidant molecules. DESIGN AND METHODS:Differentiated THP-1 were incubated in the presence or absence of iron-as...

journal_title：Clinical biochemistry

authors： Marcil V,Lavoie JC,Emonnot L,Seidman E,Levy E

更新日期：2011-07-01 00:00:00

abstract：:A method is described for xylose determination on the Ciba-Corning 550 Express that utilizes the slower enzymatic action of glucose dehydrogenase (GDH) on D-xylose, after prior removal of glucose. Glucose oxidase is added to serum or urine and incubated for 120 min at 37 degrees C. After incubation, a perchloric acid ...

journal_title：Clinical biochemistry

authors： Mori L

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND AND AIM:TGF-β1 has been previously reported to be involved in the pathogenesis of atherosclerosis. The aim of the present study was to assess whether functional gene polymorphisms of TGF-β1 and its key receptor TGF-β receptor type II (TGFBR2) contribute as risk factors to the onset and severity of atheroscle...

journal_title：Clinical biochemistry

authors： Yang M,Zhu M,Tang L,Zhu H,Lu Y,Xu B,Jiang J,Chen X

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVES:Salivary analysis is a noninvasive alternative that may be more acceptable to patients, especially children. As such, it has the potential for incorporation into comprehensive, dynamic investigations of metabolic dysfunctions - a significant advancement over a single time point serum analysis. In this study,...

journal_title：Clinical biochemistry

authors： Chiu SK,Collier CP,Clark AF,Wynn-Edwards KE

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVES:Measurements of myoglobin and creatine kinase (CK)-MB isoforms have been suggested to be sensitive tests for the early diagnosis of myocardial infarction (MI). We have investigated the utility of myoglobin, creatine kinase (CK)-MB isoforms and creatine kinase MB mass (CK-MBm) in early diagnosis of MI using c...

journal_title：Clinical biochemistry

authors： Penttilä K,Koukkunen H,Halinen M,Rantanen T,Pyörälä K,Punnonen K,Penttilä I

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVES:We have previously identified three minor immunophilins of molecular weights 37 kDa, 14 kDa, and 5-8 kDa capable of binding tacrolimus and sirolimus. DESIGN AND METHODS:When tested against pure preparations of five sirolimus metabolites, the 14 kDa protein had almost no cross-reactivity, the 37 kDa protein ...

journal_title：Clinical biochemistry

authors： Davis DL,Murthy JN,Gallant-Haidner H,Yatscoff RW,Soldin SJ

更新日期：2000-02-01 00:00:00

abstract：:This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. ...

journal_title：Clinical biochemistry

authors： Delvin EE

更新日期：2006-04-27 00:00:00

abstract：BACKGROUND:While investigating estrogen response element (ERE) binding properties of human estrogen receptor-α (hERα) in breast cancer cytosols, other ERE-binding proteins (ERE-BP) were observed. DESIGN AND METHODS:Recognition properties of ERE-BP were evaluated by electrophoretic mobility shift assays (EMSA) with ERE...

journal_title：Clinical biochemistry

authors： Kruer TL,Cummins TD,Powell DW,Wittliff JL

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVES:The newly developed glomerular filtration rate (GFR)-estimating equations developed by the CKD-EPI Collaboration and Feng et al. (2013) that are based on standardized serum cystatin C (ScysC), combined/not combined with serum creatinine (Scr), require further validation in China. We compared the performance ...

journal_title：Clinical biochemistry

authors： Guo X,Qin Y,Zheng K,Gong M,Wu J,Shou W,Cheng X,Xia L,Xu E,Li X,Qiu L

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVES:Osteoprotegerin (OPG) is a regulator of bone and vascular homeostasis and acts as a decoy receptor for proapoptotic TNF-related apoptosis-inducing ligand (TRAIL). DESIGN AND METHODS:We assessed pericardial and serum levels of OPG and TRAIL in pericardial effusions (PE) of malignant (mPE, n=24) or non-malign...

journal_title：Clinical biochemistry

authors： Karatolios K,Pankuweit S,Goettsch C,Hofbauer LC,Timmesfeld N,Al-Fakhri N,Maisch B,Schoppet M

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:According to the prevailing theory about the genetic background to lactose intolerance, there are three genotypes but only two adult physiological phenotypes: lactase persistence in individuals with the CT and TT genotypes and lactase non-persistence in individuals with the CC genotype. However, analysis of ...

journal_title：Clinical biochemistry

authors： Dzialanski Z,Barany M,Engfeldt P,Magnuson A,Olsson LA,Nilsson TK

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVES:To evaluate the association between plasma lipids and insulin and variation in the genes for apolipoproteins (APO) E (CfoI), B (insertion/deletion), C1 (HpaI), and C3 (C-482T, C3238G) in a population-based Czech Slavonic study. DESIGN AND METHODS:In 131 men and 154 women, polymorphisms were investigated usi...

journal_title：Clinical biochemistry

authors： Hubacek JA,Waterworth DM,Poledne R,Pitha J,Skodová Z,Humphries SE,Talmud PJ

更新日期：2001-03-01 00:00:00

abstract：:Mycophenolate mofetil is widely used in combination with either cyclosporine or tacrolimus for rejection prophylaxis in renal and heart transplant patients. Although not monitored routinely nearly to the degree that other agents such as cyclosporine or tacrolimus, there is an expanding body of experimental evidence fo...

journal_title：Clinical biochemistry

authors： Shaw LM,Korecka M,DeNofrio D,Brayman KL

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVES:Blood sampling/handling alters matrix metalloproteinases (MMP) and tissue inhibitors of metalloproteinases (TIMP) expression. The aim of this study is to evaluate the effects of high molecular weight heparin on MMP and TIMP expression in blood. DESIGN AND METHODS:We analyzed by gelatin zymography and ELISA ...

journal_title：Clinical biochemistry

authors： Mannello F,Jung K,Tonti GA,Canestrari F

更新日期：2008-12-01 00:00:00

abstract：:Fourteen antirheumatoid drugs were tested for their effects on the in vitro hyaluronidase activity of normal human serum. Four drugs produced significant changes in enzyme activity. Different results were obtained with ovine testicular hyaluronidase when diluted with either saline or inactivated human serum. No increa...

journal_title：Clinical biochemistry

authors： Salkie ML,Hannah CL,McNeil EM

更新日期：1976-08-01 00:00:00

abstract：OBJECTIVES:Effects of treatment with dehydroepiandrosterone (DHEA) on oxidative energy metabolism in rat liver and brain mitochondria were examined. DESIGN AND METHODS:Young adult rats were administered DHEA (0.1, 0.2, 1.0 or 2.0 mg/kg body weight) by subcutaneous route for 7 consecutive days. RESULTS:DHEA treatment ...

journal_title：Clinical biochemistry

authors： Patel MA,Katyare SS

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVES:Oxidative stress plays a role in the pathogenesis in patients with HCV infection. The objective of this study was to evaluate oxidant and antioxidant biomarkers in patients with HCV. DESIGN AND METHODS:Serum malonaldehyde (MDA) and nitric oxide (NO) levels and the activities of myeloperoxidase (MPO), aryles...

journal_title：Clinical biochemistry

authors： Ali EM,Shehata HH,Ali-Labib R,Esmail Zahra LM

更新日期：2009-09-01 00:00:00

abstract：:We describe a simple direct extraction method for the gas-liquid chromatography determination of serum valproic acid. The working range for the assay is 2-180 mg/L and our within-run precision was 5.8 and 4.3% at the 40 and 90 mg/L concentrations respectively. Hemolyzed and lipemic sera as well as samples from patient...

journal_title：Clinical biochemistry

authors： Leroux M,Budnik D,Hall K,Irvine-Meek J,Otten N,Seshia S

更新日期：1981-04-01 00:00:00

abstract：OBJECTIVES:An increase in oxidative stress may contribute to the development of oxidative protein damage in the aging rat skeletal muscle. Our aim was to reveal protein carbonyl (PCO), advanced oxidation protein products (AOPP), a novel marker of oxidative stress, and protein thiol (P-SH) levels as markers of protein o...

journal_title：Clinical biochemistry

authors： Cakatay U,Telci A,Kayali R,Tekeli F,Akçay T,Sivas A

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:The aldosterone/renin ratio (ARR) is recommended to screen for primary aldosteronism (PA) in hypertension. We estimated fully automated chemiluminescence immunoassays (CLIA) for plasma aldosterone concentrations (PAC) and plasma direct renin concentrations (PRC) and investigated their reference intervals in ...

journal_title：Clinical biochemistry

authors： Deng L,Xiong Z,Li H,Lei X,Cheng L

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Elevations of serum cardiac troponin T (cTnT) have been described in patients with end stage chronic kidney disease (CKD) although the mechanism is unknown, whether from increased production or decreased clearance. Less is known about cTnT in short term changes in renal function and in lesser degrees of rena...

journal_title：Clinical biochemistry

authors： Chung JZ,Dallas Jones GR

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVE:To establish a ELISA assay to measure release of type 1-phospholipase A2 propeptide from activated granulocytes. Human type 1-prophospholipase A2 (1-proPLA2) is biosynthesized and stored as inactive zymogen. Activation involves tryptic-like cleavage at the N-terminus, with equimolar release of the heptapeptid...

journal_title：Clinical biochemistry

authors： Rae D,Sumar N,Beechey-Newman N,Gudgeon M,Hermon-Taylor J

更新日期：1995-02-01 00:00:00

abstract：OBJECTIVES:Coenzyme Q(10) (CoQ(10)) is an essential electron carrier in the mitochondrial respiratory chain and a strong antioxidant. Signs associated with skin alteration and mitochondrial dysfunction have been observed in patients with fibromyalgia (FM). The aim of this study was to analyze CoQ(10) levels, mitochondr...

journal_title：Clinical biochemistry

authors： Cordero MD,Moreno-Fernández AM,Carmona-López MI,Sánchez-Alcázar JA,Rodríguez AF,Navas P,de Miguel M

更新日期：2010-09-01 00:00:00

abstract：:We report a sensitive and specific method for the determination of AY-25,712 concentrations in rat, dog and human serum by liquid chromatography with UV detection. The detection limit is 25 ng/mL, based on 2 mL of serum or plasma. The method has been validated in human volunteers receiving single oral doses of AY-25,7...

journal_title：Clinical biochemistry

authors： Gonzalez R,Thibeault D

更新日期：1983-08-01 00:00:00

abstract：CONTEXT:Knee arthroplasty surgery is significant trauma, leading to an activated immune system causing inflammation and oxidative stress. Many current biomarkers are invasive, costly, and often slow to analyse, limiting their use for rapid inflammatory measurements. OBJECTIVES:We have examined the use of urinary neopt...

journal_title：Clinical biochemistry

authors： Baxter-Parker G,Roffe L,Cross S,Frampton C,Hooper GJ,Gieseg SP

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVES:This study explored the relationship between oxidative stress biomarkers and stability of carotid plaque. We decided to analyze the broad range of parameters describing oxidative stress in patients with carotid stenosis. DESIGN AND METHODS:124 consecutive patients undergoing carotid endarterectomy were enro...

journal_title：Clinical biochemistry

authors： Rozalski R,Migdalski A,Gackowski D,Guz J,Siomek A,Foksinski M,Szpila A,Zarakowska E,Majer M,Jawien A,Olinski R

更新日期：2013-08-01 00:00:00

abstract：:An ion-exchange chromatographic procedure is described which facilitates the determination of beta-chain aminoterminal modified glycated hemoglobin. The procedure includes an erythrocyte lysis reagent which eliminates the labile aldimine component (pre-A1c) and a two-stage elution step which separates HbA, 1a + b from...

journal_title：Clinical biochemistry

authors： Jaynes PK,Willis MC,Chou PP

更新日期：1985-02-01 00:00:00