Controversies in urinary iodine determinations.

abstract：OBJECTIVES:Measurement of serotonin concentrations in blood is considered to be important for the clinical studies of diseases involving vascular endothelial injury. We have developed a high-performance liquid chromatographic (HPLC) method for measurement of serotonin level in platelet-poor plasma (PPP). METHODS:Venou...

journal_title：Clinical biochemistry

authors： Hirowatari Y,Hara K,Kamihata H,Iwasaka T,Takahashi H

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVES:Coenzyme Q(10) (CoQ(10)) is an essential electron carrier in the mitochondrial respiratory chain and a strong antioxidant. Signs associated with skin alteration and mitochondrial dysfunction have been observed in patients with fibromyalgia (FM). The aim of this study was to analyze CoQ(10) levels, mitochondr...

journal_title：Clinical biochemistry

authors： Cordero MD,Moreno-Fernández AM,Carmona-López MI,Sánchez-Alcázar JA,Rodríguez AF,Navas P,de Miguel M

更新日期：2010-09-01 00:00:00

abstract：:We assessed the diagnostic value of four commercially available methods for determining pancreatic lipase (LPS) in serum (the turbidimetric procedure from Boehringer, two enzymatic approaches from Kodak and Poli, and an immunochemical assay) in a population of 46 hospitalized patients with acute abdominal pain. In 31 ...

journal_title：Clinical biochemistry

authors： Panteghini M,Pagani F,Bonora R,Alebardi O,Ceriotti F

更新日期：1991-12-01 00:00:00

abstract：OBJECTIVES:Increased free radical activity and lipid peroxidation may be implicated in the pathogenesis of preeclampsia. This study was initiated to assess antioxidant enzyme and trace metals's status in preeclampsia. DESIGN AND METHODS:The comparison was made between the pregnant women with or without preeclampsia an...

journal_title：Clinical biochemistry

authors： Ilhan N,Ilhan N,Simsek M

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVES:To ascertain whether or not the change in blood collection tubes for plasma glucose from fluoride/oxalate to citrate/fluoride/EDTA has had an effect upon the glucose results. METHODS:Plasma glucose results from fasting patients from 2007 to 2012 were extracted from the laboratory information system. The dat...

journal_title：Clinical biochemistry

authors： Norman M,Jones I

更新日期：2014-05-01 00:00:00

abstract：INTRODUCTION:Barricor™ Vacutainers® are a novel non-gel separator blood collection tube. These tubes enable faster pre-analytical processing which could reduce turnaround time and be beneficial in an acute care setting. We sought to evaluate the bias, stability, and integrity of plasma generated from these tubes compar...

journal_title：Clinical biochemistry

authors： Fournier JE,Northrup V,Clark C,Fraser J,Howlett M,Atkinson P,Shea JL

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Increased levels of circulating endostatin predicts cardiovascular morbidity and impaired kidney function in the general population. The utility of endostatin as a risk marker for mortality in the emergency department (ED) has not been reported. AIM:Our main aim was to study the association between plasma e...

journal_title：Clinical biochemistry

authors： Carlsson AC,Wessman T,Larsson A,Leijonberg G,Tofik R,Ärnlöv J,Melander O,Ruge T

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:To externally validate a clinical decision rule incorporating heart fatty acid binding protein (h-FABP), high-sensitivity troponin (hs-cTn) and electrocardiogram (ECG) for the detection of acute myocardial infarction (AMI) on presentation to the Emergency Department. We also investigated whether this clinical...

journal_title：Clinical biochemistry

authors： Van Hise CB,Greenslade JH,Parsonage W,Than M,Young J,Cullen L

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Vitamin D (25-OHD) physiological functions have been expanded beyond traditional bone health, increasing the importance of its estimation in Laboratory Medicine, which renders validation of available methods mandatory. AIMS AND METHODS:We evaluated some preanalytical and analytical aspects of 25-OHD determi...

journal_title：Clinical biochemistry

authors： Bianchi S,Maffei S,Prontera C,Battaglia D,Vassalle C

更新日期：2012-12-01 00:00:00

abstract：:We describe a fast and efficient method for the isolation of drugs from blood serum by use of the DU PONT PREP I Automated Sample Processor and octadecyl bonded phase columns. Drugs are selectively adsorbed onto C18 bonded phase and eluted with methanol. The recovered residue is essentially free of sample matrix chrom...

journal_title：Clinical biochemistry

authors： Repique EV,Sacks HJ,Farber SJ

更新日期：1981-08-01 00:00:00

abstract：:Comparison of the turbidimetric immunoassay of haptoglobin with a reference method (the RID technique with appropriate correction for phenotype) clearly showed the turbidimetric assay to be phenotype-dependent. Correction factors for the three main phenotypes were calculated and reference values determined. The observ...

journal_title：Clinical biochemistry

authors： van Rijn HJ,van der Wilt W,Stroes JW,Schrijver J

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:Vitamin D-binding protein (DBP) is the main systemic transporter of 1.25(OH)2D3 and is essential for its cellular endocytosis. There are two known polymorphisms in exon 11 of the DBP gene resulting in amino acid variants: GAT-->GAG substitution replaces aspartic acid by glutamic acid in codon 416; and ACG-->...

journal_title：Clinical biochemistry

authors： Ongagna JC,Pinget M,Belcourt A

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVES:Homologous recombination is a frequent phenomenon in multigene families and as such it occurs several times in both the alpha- and beta-like globin gene families. In numerous occasions, genetic recombination has been previously implicated as a major mechanism that drives mutagenesis in the human globin gene ...

journal_title：Clinical biochemistry

authors： Borg J,Georgitsi M,Aleporou-Marinou V,Kollia P,Patrinos GP

更新日期：2009-12-01 00:00:00

abstract：:1. When a malignant growth is developing in a patient, one often observes in the serum an increased activity of serum enzymes due to necrosis and increased membrane permeability caused by the altered metabolism of malignant cells. Conversely, I considered it interesting to check the enzymes of the malate-aspartate sh...

journal_title：Clinical biochemistry

authors： Nyandieka HS

更新日期：1977-08-01 00:00:00

abstract：:High-sensitivity cardiac troponin (hs-cTn) assays have been used clinically by thousands of physicians in many countries throughout the world since their clinical introduction seven years ago. In the early diagnosis of myocardial infarction (MI), beyond doubt the most important indication of hs-cTn assays, these simpl...

journal_title：Clinical biochemistry

authors： Twerenbold R,Boeddinghaus J,Nestelberger T,Wildi K,Rubini Gimenez M,Badertscher P,Mueller C

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVES:Salivary analysis is a noninvasive alternative that may be more acceptable to patients, especially children. As such, it has the potential for incorporation into comprehensive, dynamic investigations of metabolic dysfunctions - a significant advancement over a single time point serum analysis. In this study,...

journal_title：Clinical biochemistry

authors： Chiu SK,Collier CP,Clark AF,Wynn-Edwards KE

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVES:The plasma apolipoprotein B (apo B) concentrations have been considered to be a more accurate representation of atherogenic particles and it has been proposed that the formula LDL-C (mmol/L) = 0.41TC - 0.32TG + 1.70apo B - 0.27 is reliable for the estimation of LDL-C (Clin Chem 1997; 43: 808-15). We undertoo...

journal_title：Clinical biochemistry

authors： Bairaktari E,Hatzidimou K,Tzallas C,Vini M,Katsaraki A,Tselepis A,Elisaf M,Tsolas O

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVES:The aim of the present study was to establish the range of chitotriosidase (CT) activity in normal individuals, patients with Gaucher disease (GD) and Niemann-Pick disease (NPD), types A or B. The kinetics of CT in these three groups was also investigated. DESIGN AND METHODS:CT activity, as well as Km, Vmax...

journal_title：Clinical biochemistry

authors： Wajner A,Michelin K,Burin MG,Pires RF,Pereira ML,Giugliani R,Coelho JC

更新日期：2004-10-01 00:00:00

abstract：INTRODUCTION:Gaucher disease (GD) is caused by a deficiency of β-glucosidase (GCase), leading to accumulation of glucosylceramide (GlcC) and glucosylsphingosine (Lyso-Gb1). Lyso-Gb1 is a reliable biomarker for GD. OBJECTIVES:This study aims to develop a simple, effective and accurate method for the screening and diagn...

journal_title：Clinical biochemistry

authors： Tang C,Jia X,Tang F,Liu S,Jiang X,Zhao X,Sheng H,Peng M,Liu L,Huang Y

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:The aldosterone/renin ratio (ARR) is recommended to screen for primary aldosteronism (PA) in hypertension. We estimated fully automated chemiluminescence immunoassays (CLIA) for plasma aldosterone concentrations (PAC) and plasma direct renin concentrations (PRC) and investigated their reference intervals in ...

journal_title：Clinical biochemistry

authors： Deng L,Xiong Z,Li H,Lei X,Cheng L

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVES:We evaluated the effects of lifestyle modification (LM) on lipid profile, oxidative stress and serum-stimulated human coronary artery endothelial cell (HCAEC) viability in coronary artery disease (CAD) patients after 6months. DESIGN AND METHODS:Thirty patients with CAD were randomly assigned to LM intervent...

journal_title：Clinical biochemistry

authors： Srimahachota S,Wunsuwan R,Siritantikorn A,Boonla C,Chaiwongkarjohn S,Tosukhowong P

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the potential diagnostic value of apolipoprotein E (ApoE) measurements in pediatric patients with invasive bacterial infections. DESIGN AND METHOD:A total of 185 pediatric patients were enrolled in this study, including 94 patients with confirmable infections and 91 patients without confirmable i...

journal_title：Clinical biochemistry

authors： Wang C,Wang Y,Wang A,Fu P,Yang Y

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVE:Direct measurement of chemical constituents in complex biologic matrices without the use of analyte specific reagents could be a step forward toward the simplification of clinical biochemistry. Problems related to reagents such as production errors, improper handling, and lot-to-lot variations would be elimin...

journal_title：Clinical biochemistry

authors： Jessen TE,Höskuldsson AT,Bjerrum PJ,Verder H,Sørensen L,Bratholm PS,Christensen B,Jensen LS,Jensen MA

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVES:We undertook the present study to investigate the possible relation between total antioxidant capacity (TAC) and tumor marker (TM) values in serum samples of patients with and without gastrointestinal tract and prostate tumors. DESIGN AND METHODS:We measured the TAC using trolox equivalent antioxidant capac...

journal_title：Clinical biochemistry

authors： López Vélez M,Martínez Martínez F

更新日期：2011-09-01 00:00:00

abstract：:Steroids play an important role in sperm production and quality. These hormones have been extensively studied in blood, but poorly investigated in semen. The purpose of our study was to evaluate the relationship between sperm quality and steroid profiles in blood and semen in a small cohort of young Swiss men. Another...

journal_title：Clinical biochemistry

authors： Zufferey F,Rahban R,Garcia A,Gagnebin Y,Boccard J,Tonoli D,Jeanneret F,Stettler E,Senn A,Nef S,Rudaz S,Rossier MF

更新日期：2018-12-01 00:00:00

abstract：:Thyroxine binding protein characteristics were defined in 6 normal subjects, 4 with thyroxine binding globulin (TBG) deficiency, 3 with TBG increase, one with hyperthyroxinemic dysalbuminemia, 7 with severe non-thyroidal illness, and 3 with chronic renal failure. Free thyroxine was measured by Sephadex partition in pl...

journal_title：Clinical biochemistry

authors： Keane PM,Walker WH,Thornton G,Rodbard D

更新日期：1986-02-01 00:00:00

abstract：OBJECTIVES:To examine the diagnostic validity of bone alkaline phosphatase (BAP) in serum (a marker of bone formation) and of urinary excretion of pyridinium cross-links (PYR) (a marker of bone resorption) for detection of bone metastases. DESIGN AND METHODS:Two heterogeneous immunoassays were employed for determinati...

journal_title：Clinical biochemistry

authors： Withold W,Georgescu G,Khakzad H,Vosberg H,Mueller-Gaertner HW,Reinauer H

更新日期：1995-10-01 00:00:00

abstract：:The toxicity of carbon monoxide has been recognized for long throughout history and is unquestionably the leading cause of unintentional poisoning deaths in the Western countries. The severity of poisoning is dependent upon environmental and human factor. The leading pathophysiological mechanism resides in the ability...

journal_title：Clinical biochemistry

authors： Lippi G,Rastelli G,Meschi T,Borghi L,Cervellin G

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVES:Hepatic overproduction of apolipoprotein B (apoB)-containing lipoproteins appears to be a common cause of hyperlipoproteinemia in humans. Patients with overproduction states secrete denser cholesterol ester-rich lipoprotein particles which are highly atherogenic. The formation of apoB particles involves a ve...

journal_title：Clinical biochemistry

authors： Adeli K,Mohammadi A,Macri J

更新日期：1995-04-01 00:00:00

abstract：OBJECTIVES:Stable isotope dilution coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS) is the sensitive method for screening for various inherited metabolic disorders using dried blood spots (DBSs). We present a method for LC-MS/MS determination of succinyladenosine (SAdo) and succinylaminoimidazole ...

journal_title：Clinical biochemistry

authors： Zikanova M,Krijt J,Skopova V,Krijt M,Baresova V,Kmoch S

更新日期：2015-01-01 00:00:00