Progesterone-mediated potentiation of spinal sufentanil in rats.

abstract：:In the past, it was common practice to use a high tidal volume (VT) during intraoperative ventilation, because this reduced the need for high oxygen fractions to compensate for the ventilation-perfusion mismatches due to atelectasis in a time when it was uncommon to use positive end-expiratory pressure (PEEP) in the o...

journal_title：Anesthesia and analgesia

authors： Hol L,Nijbroek SGLH,Schultz MJ

更新日期：2020-12-01 00:00:00

abstract：:Lidocaine and MgSO4 are often coadministered to patients with pregnancy-induced hypertension. This study examined whether MgSO4 alters the lidocaine-seizure threshold in the rat and, if so, whether systemic MgSO4 administration is as effective as intracerebroventricular MgSO4 infusion. In Experiment 1, rats were admin...

journal_title：Anesthesia and analgesia

authors： Kim YJ,McFarlane C,Warner DS,Baker MT,Choi WW,Dexter F

更新日期：1996-12-01 00:00:00

abstract：UNLABELLED:Clinical pathways are being introduced by hospitals to reduce costs and control unnecessary variation in care. We studied 766 inpatients to measure the impact of a perioperative clinical pathway for patients undergoing knee replacement surgery on hospital costs. One hundred twenty patients underwent knee rep...

journal_title：Anesthesia and analgesia

authors： Macario A,Horne M,Goodman S,Vitez T,Dexter F,Heinen R,Brown B

更新日期：1998-05-01 00:00:00

abstract：:The hemodynamic effects of esmolol were studied in 40 patients scheduled for elective coronary artery surgery to determine whether the administration of esmolol in chronically beta-blocked patients would result in additional attenuation of sympathetically mediated hemodynamic stress responses to noxious stimuli. Patie...

journal_title：Anesthesia and analgesia

authors： de Bruijn NP,Croughwell N,Reves JG

更新日期：1987-02-01 00:00:00

abstract：:The development of a technique for studying spinal dorsal horn electrophysiology in intact, awake, drug-free cats enables the study of spinal sites and mechanisms of action of anesthetic and analgesic agents in a system that more closely reflects normal physiology. Using this technique, we reevaluated the effect of ke...

journal_title：Anesthesia and analgesia

authors： Collins JG

更新日期：1986-11-01 00:00:00

abstract：:Fentanyl pharmacokinetics was compared in two groups of adult patients, one group (n = 5) aged less than 50 years, and one group (n = 4) aged greater than 60 years. Despite equivalent doses of fentanyl (10 microgram/kg IV), serum drug concentrations were significantly higher in the older patient group. This was reflec...

journal_title：Anesthesia and analgesia

authors： Bentley JB,Borel JD,Nenad RE Jr,Gillespie TJ

更新日期：1982-12-01 00:00:00

abstract：IMPLICATIONS:A low-dose (4 mg), low-volume (0.8 mL), low-flow (2 min) technique with hyperbaric bupivacaine toward the dependent side oriented injection and maintenance of the lateral decubitus position for 10 min produced selective spinal anesthesia with rapid recession of motor block and early discharge home. ...

journal_title：Anesthesia and analgesia

authors： Valanne JV,Korhonen AM,Jokela RM,Ravaska P,Korttila KK

更新日期：2001-12-01 00:00:00

abstract：UNLABELLED:We constructed a single-dose response curve for succinylcholine in 30 obese adolescents during thiopental-fentanyl anesthesia administration by using 100 microg/kg, 150 microg/kg, or 250 microg/kg IV. The maximal response (percent depression of neuromuscular function) of the adductor pollicis to supramaximal...

journal_title：Anesthesia and analgesia

authors： Rose JB,Theroux MC,Katz MS

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Three cases of drug-induced liver injury (DILI) have been reported after desflurane anesthesia. However, no previous reports have detected serum autoantibodies such as that reported with DILI from halothane or isoflurane. METHODS AND RESULTS:We describe the first documentation of cytochrome P450 2E1 IgG4 au...

journal_title：Anesthesia and analgesia

authors： Anderson JS,Rose NR,Martin JL,Eger EI,Njoku DB

更新日期：2007-06-01 00:00:00

abstract：UNLABELLED:Tropisetron is a 5-hydroxytryptamine subtype 3 receptor antagonist that is primarily used in the prevention of chemotherapy-induced nausea and vomiting. We evaluated the prophylactic effect of tropisetron on postoperative nausea and vomiting associated with epidural morphine. Dexamethasone and saline served ...

journal_title：Anesthesia and analgesia

authors： Wang JJ,Tzeng JI,Ho ST,Chen JY,Chu CC,So EC

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Local anesthetics cause reversible block of pain and robustly inhibit TWIK-related K channel (TREK-1) currents. Before local anesthesia onset, injection of local anesthetics can cause unwanted transient pain. TREK-1 is an anesthetic-sensitive potassium channel that when inhibited produces pain. A disordered ...

journal_title：Anesthesia and analgesia

authors： Pavel MA,Chung HW,Petersen EN,Hansen SB

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Sigma (sigma)-receptor agonists attenuate brain injury after experimental focal cerebral ischemia in several species. We tested the hypothesis that the potent, prototypical sigma(1)-receptor agonist, 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP), protects neurons by a mechanism involving the antiapoptotic pro...

journal_title：Anesthesia and analgesia

authors： Yang S,Bhardwaj A,Cheng J,Alkayed NJ,Hurn PD,Kirsch JR

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Previous animal and human studies suggested that nicotine might have an antinociceptive effect. We hypothesized that the preoperative application of a 7 mg nicotine patch would result in reduced postoperative analgesic requirements in patients undergoing radical retropubic prostatectomy (RRP) under general a...

journal_title：Anesthesia and analgesia

authors： Habib AS,White WD,El Gasim MA,Saleh G,Polascik TJ,Moul JW,Gan TJ

更新日期：2008-09-01 00:00:00

abstract：UNLABELLED:The Valsalva maneuver in the awake patient and the ventilation maneuver in the tracheally intubated anesthetized patient are two provocation methods to detect a patent foramen ovale (PFO) by means of contrast transesophageal echocardiography. In 60 patients undergoing posterior fossa surgery, a contrast agen...

journal_title：Anesthesia and analgesia

authors： Greim CA,Trautner H,Krämer K,Zimmermann P,Apfel CC,Roewer N

更新日期：2001-05-01 00:00:00

abstract：UNLABELLED:We compared three ventilators-Servo 900C (Siemens Medical Systems, Danvers, MA), Aestiva 3000 (Datex-Ohmeda, Madison, WI), and NAD 6000 (North American Dräger, Telford, PA)-set to deliver pressure control ventilation using an infant test lung model. Ventilator settings were selected to test "near-maximum" se...

journal_title：Anesthesia and analgesia

authors： Stayer SA,Bent ST,Skjonsby BS,Frolov A,Andropoulos DB

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Heart rate variability might predict arrhythmias after coronary artery bypass grafting. METHODS:Off-line processing of 10-min electrocardiogram recordings of consecutive patients provided R-R intervals for time domain, frequency domain, Poincaré, and point correlation analyses and subsequent association wit...

journal_title：Anesthesia and analgesia

authors： Chamchad D,Djaiani G,Jung HJ,Nakhamchik L,Carroll J,Horrow JC

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Implementing Bayesian methods in a model-based closed-loop system requires the integration of a standard response model with a patient-specific response model. This process makes use of specific modeling weights, called Bayesian variances, which determine how the specific model can deviate from the standard ...

journal_title：Anesthesia and analgesia

authors： De Smet T,Struys MM,Greenwald S,Mortier EP,Shafer SL

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Intrathecal neostigmine not only produces analgesia but also severe nausea. In contrast, epidural neostigmine enhances opioid and local anesthetic analgesia without causing nausea. Previous studies examined only single epidural neostigmine bolus administration and did not assess the efficacy of continuous ep...

journal_title：Anesthesia and analgesia

authors： Ross VH,Pan PH,Owen MD,Seid MH,Harris L,Clyne B,Voltaire M,Eisenach JC

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Spinal cord monitoring is associated with a significantly lower rate of neurologic deficits after deformity surgery, and has been shown to have predictive value in cervical, thoracic, and lumbar surgery. Lower extremity motor evoked potentials (MEPs) are particularly sensitive to anesthetics and physiologic ...

journal_title：Anesthesia and analgesia

authors： Deiner SG,Kwatra SG,Lin HM,Weisz DJ

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:There have been numerous studies published on the ProSeal laryngeal mask airway (PLMA). However, few have investigated its utility in a large practice setting. We sought to gather comprehensive data about the characteristics, efficacy, and safety of its use by a representative group of anesthesiologists work...

journal_title：Anesthesia and analgesia

authors： Goldmann K,Hechtfischer C,Malik A,Kussin A,Freisburger C

更新日期：2008-12-01 00:00:00

abstract：:We report a case of a 75-yr-old female patient in whom motor deficits and paresthesias occurred after lumbar epidural analgesia. These symptoms were eventually found to be due to a tethered cord syndrome. An epidural catheter was inserted for analgesia after colon surgery. The postoperative course was characterized by...

journal_title：Anesthesia and analgesia

authors： Jetzek-Zader M,Peterschulte G,Ludwig U,Lipfert P

更新日期：2004-07-01 00:00:00

abstract：:We assessed the effect of small clonidine doses on anxiolysis, analgesia, and hemodynamic stability in patients undergoing abdominal hysterectomy. A total of 61 patients, ASA status I-II, were randomly assigned to receive either oral clonidine 100 microg (n = 29) or placebo (n = 32) before surgery and 24 h after surge...

journal_title：Anesthesia and analgesia

authors： Hidalgo MP,Auzani JA,Rumpel LC,Moreira NL Jr,Cursino AW,Caumo W

更新日期：2005-03-01 00:00:00

abstract：UNLABELLED:We evaluated the timing effect of a 10-mg IV administration of dexamethasone on its efficacy as a prophylactic antiemetic on postoperative nausea and vomiting (PONV). One hundred twenty women (n = 40 in each of three groups) undergoing abdominal total hysterectomy under general anesthesia were enrolled in th...

journal_title：Anesthesia and analgesia

authors： Wang JJ,Ho ST,Tzeng JI,Tang CS

更新日期：2000-07-01 00:00:00

abstract：:Ketamine has many neuromuscular effects in vitro. Its neuromuscular effects in vivo have been controversial and inconsistent. To systematically examine its neuromuscular effects over a wide dose range and its interaction with all popular nondepolarizing neuromuscular relaxants, the effects of ketamine 2, 5, and 10 mg/...

journal_title：Anesthesia and analgesia

authors： Tsai SK,Lee C

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Tissue factor pathway inhibitor (TFPI) is a 40-kDa, endogenous protein that inhibits tissue factor (TF)-initiated coagulation by bonding with activated factor X (FXa). The TFPI/FXa complex then subsequently binds with TF/activated factor VII (FVIIa) complex, ultimately inhibiting thrombin generation. Heparin...

journal_title：Anesthesia and analgesia

authors： Audu P,Nielsen VG,Armstead V,Powell G,Kim J,Kim L,Mehta M

更新日期：2006-10-01 00:00:00

abstract：:With the increased use of intraoperative transesophageal echocardiography, patent foramen ovale (PFO) has become a common finding during heart surgery. This finding presents a difficult dilemma for cardiac surgeons, since the impact of intraoperatively diagnosed PFOs on postoperative outcome is unknown. Changes in the...

journal_title：Anesthesia and analgesia

authors： Sukernik MR,Bennett-Guerrero E

更新日期：2007-09-01 00:00:00

abstract：UNLABELLED:Isoflurane reduces myocardial infarct size during early reperfusion by activating phosphatidylinositol-3-kinase (PI3K) signaling. We tested the hypothesis that this cardioprotection against reperfusion injury is enhanced by morphine and that a decrease in apoptosis plays a role in preservation of myocardial ...

journal_title：Anesthesia and analgesia

authors： Weihrauch D,Krolikowski JG,Bienengraeber M,Kersten JR,Warltier DC,Pagel PS

更新日期：2005-10-01 00:00:00

abstract：UNLABELLED:Hypothermia after induction of general anesthesia results largely from core-to-peripheral redistribution of body heat. Both central inhibition of tonic thermoregulatory vasoconstriction in arteriovenous shunts and anesthetic-induced arteriolar and venous dilation contribute to this redistribution. Ketamine, ...

journal_title：Anesthesia and analgesia

authors： Ikeda T,Kazama T,Sessler DI,Toriyama S,Niwa K,Shimada C,Sato S

更新日期：2001-10-01 00:00:00

abstract：:The tandem pore domain K channel family mediates background K currents present in excitable cells. Currents passed by certain members of the family are enhanced by volatile anesthetics, thus suggesting a novel mechanism of anesthesia. The newest member of the family, termed TRESK (TWIK [tandem pore domain weak inward ...

journal_title：Anesthesia and analgesia

authors： Liu C,Au JD,Zou HL,Cotten JF,Yost CS

更新日期：2004-12-01 00:00:00

abstract：UNLABELLED:We designed this study to assess the efficacy of dolasetron compared with clonidine and placebo in prophylaxis of postanesthetic shivering. We included 90 patients undergoing elective abdominal or urologic surgery. The patients were randomly assigned to one three groups (each group n = 30) using a double-bli...

journal_title：Anesthesia and analgesia

authors： Piper SN,Röhm KD,Maleck WH,Fent MT,Suttner SW,Boldt J

更新日期：2002-01-01 00:00:00