The potency of succinylcholine in obese adolescents.

abstract：BACKGROUND:Severe exacerbation of chronic neuropathic pain often requires morphine in patients already treated with drugs such as tricyclic antidepressants, carbamazepine and gabapentin. However, it is unclear if a combination of these drugs intensifies the effects of morphine on the respiratory system and, if so, whet...

journal_title：Anesthesia and analgesia

authors： Kozer E,Levichek Z,Hoshino N,Kapur B,Leombruno J,Taguchi N,Garcia-Bournissen F,Koren G,Ito S

更新日期：2008-10-01 00:00:00

abstract：:A 6-year experience in the anesthetic management of 34 successful whole-lung lavages on 11 adult patients with pulmonary alveolar proteinosis is described. All patients were radiographically, physiologically, and symptomatically improved after the procedures. The anesthetic protocol for lung lavage includes: (1) unila...

journal_title：Anesthesia and analgesia

authors： Lippmann M,Mok MS

更新日期：1977-09-01 00:00:00

abstract：BACKGROUND:Sugammadex is a modified [gamma] cyclodextrin compound, which encapsulates rocuronium to provide for a rapid reversal of residual neuromuscular blockade. We tested the hypothesis that sugammadex would provide for a more rapid reversal of a moderately profound residual rocuronium-induced blockade than the com...

journal_title：Anesthesia and analgesia

authors： Sacan O,White PF,Tufanogullari B,Klein K

更新日期：2007-03-01 00:00:00

abstract：UNLABELLED:Rapacuronium (Org 9487) is a rapid-onset and short- to intermediate-acting muscle relaxant. Its 3-desacetyl metabolite, Org 9488, also exerts neuromuscular-blocking activity that may become apparent after prolonged maintenance of relaxation with rapacuronium. In this study, the pharmacokinetic behavior (n = ...

journal_title：Anesthesia and analgesia

authors： Schiere S,Proost JH,Schuringa M,Wierda JM

更新日期：1999-03-01 00:00:00

abstract：:Perioperative lung-protective ventilation (LPV) can reduce perioperative pulmonary morbidity. We hypothesized that modifying default anesthesia machine ventilator settings would increase the use of intraoperative LPV. Default tidal volume settings on our anesthesia machines were decreased from 600 to 400 mL, and defau...

journal_title：Anesthesia and analgesia

authors： Chiao SS,Colquhoun DA,Naik BI,Ma JZ,Nemergut EC,Durieux ME,Blank RS,Forkin KT

更新日期：2018-04-01 00:00:00

abstract：:The number of anesthesiology residents pursuing critical care medicine (CCM) fellowship training has been decreasing in recent years. A significant number of training positions remain unfilled each year. Possible causes of this decline were evaluated by surveying residents regarding their attitudes toward practice and...

journal_title：Anesthesia and analgesia

authors： Durbin CG Jr,McLafferty CL Jr

更新日期：1993-09-01 00:00:00

abstract：:Sodium nitroprusside-induced cyanide intoxication has been demonstrated in the laboratory animal and has been experienced clinically during induced hypotensive anesthesia. This is a care report of a successful resuscitation of a severe cardiovascular collapse secondary to suspected sodium nitroprusside-induced cyanide...

journal_title：Anesthesia and analgesia

authors： Perschau RA,Modell JH,Bright RW,Shirley PD

更新日期：1977-07-01 00:00:00

abstract：BACKGROUND:It has been shown that the combination of electroencephalogram (EEG) and auditory evoked potentials (AEP) allows a good separation of consciousness from unconsciousness. In the present study, we sought a combined EEG/AEP indicator that allows both separation of consciousness from unconsciousness and discrimi...

journal_title：Anesthesia and analgesia

authors： Horn B,Pilge S,Kochs EF,Stockmanns G,Hock A,Schneider G

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Some drugs used for sedation and anesthesia produce histopathologic central nervous system changes in juvenile animal models. These observations have raised concerns regarding the use of these drugs in pediatric patients. We summarized the findings in developing animals and describe the steps that the Food a...

journal_title：Anesthesia and analgesia

authors： Mellon RD,Simone AF,Rappaport BA

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Local anesthetics cause reversible block of pain and robustly inhibit TWIK-related K channel (TREK-1) currents. Before local anesthesia onset, injection of local anesthetics can cause unwanted transient pain. TREK-1 is an anesthetic-sensitive potassium channel that when inhibited produces pain. A disordered ...

journal_title：Anesthesia and analgesia

authors： Pavel MA,Chung HW,Petersen EN,Hansen SB

更新日期：2019-10-01 00:00:00

abstract：:Because we have noticed dramatic hemodynamic responses in brain dead patients undergoing surgery for organ donation, we analyzed the anesthetic records of cadaver organ donors. Ten records contain complete data for heart rate, blood pressure, central venous pressure, and time of incision. Systolic pressure increased b...

journal_title：Anesthesia and analgesia

authors： Wetzel RC,Setzer N,Stiff JL,Rogers MC

更新日期：1985-02-01 00:00:00

abstract：:Ten volunteers were studied during six stages of propofol sedation, namely awake (no propofol), light sedation (small dose of propofol), deep sedation (large dose), deep sedation with stimulation of the ulnar nerve, then light sedation again (small dose), and awake (recovery). Light and deep sedation were defined in t...

journal_title：Anesthesia and analgesia

authors： Andrade J,Sapsford DJ,Jeevaratnum D,Pickworth AJ,Jones JG

更新日期：1996-12-01 00:00:00

abstract：:The Meyer-Overton hypothesis predicts that anesthetic potency correlates inversely with lipophilicity; e.g., MAC times the olive oil/gas partition coefficient equals a constant of approximately 1.82 +/- 0.56 atm (mean +/- sd) for conventional inhaled anesthetics. MAC is the minimum alveolar concentration of anesthetic...

journal_title：Anesthesia and analgesia

authors： Won A,Oh I,Liao M,Sonner JM,Harris RA,Laster MJ,Brosnan R,Trudell JR,Eger EI 2nd

更新日期：2006-05-01 00:00:00

abstract：:An in vitro model was used to determine the force required to pierce bovine dura with a range of new spinal needles and to measure the subsequent leakage rate of cerebrospinal fluid (CSF). A significantly greater force was required to pierce the dura with pencil-point style needles compared to Quincke needles of the s...

journal_title：Anesthesia and analgesia

authors： Westbrook JL,Uncles DR,Sitzman BT,Carrie LE

更新日期：1994-10-01 00:00:00

abstract：:Many in vitro effects of volatile anesthetics are known, but the mechanisms of action are still under debate. Because suppression of sensory perception is one of the major goals of general anesthesia, we studied the effects of isoflurane on the processing of somatosensory information in anesthetized rats. Local iontop...

journal_title：Anesthesia and analgesia

authors： Vahle-Hinz C,Detsch O,Siemers M,Kochs E,Bromm B

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:In this study we sought to determine and compare the minimum local anesthetic volumes (MLAV) and doses (MLAD) of two concentrations of bupivacaine for epidural pain relief in labor, and to quantify the effect on dose. METHODS:Eighty women were randomized in a double-blind manner to receive a first bolus of ...

journal_title：Anesthesia and analgesia

authors： Lyons GR,Kocarev MG,Wilson RC,Columb MO

更新日期：2007-02-01 00:00:00

abstract：:A parametric study was performed in cats comparing the effects on the brainstem auditory evoked response of four anesthetic agents used either in the operating room or the laboratory: sodium pentobarbital, ketamine, halothane, and chloralose. Each anesthetic agent was administered to each of four cats in varying seque...

journal_title：Anesthesia and analgesia

authors： Cohen MS,Britt RH

更新日期：1982-04-01 00:00:00

abstract：UNLABELLED:Previous investigations of the effects of potent opioid analgesics on the heart have concentrated on effects on contraction magnitude and time course, but little is known about their effects on cytosolic Ca(2+) regulation in cardiac tissue. In this study, we sought to assess the effects of alfentanil on cont...

journal_title：Anesthesia and analgesia

authors： Graham MD,Hopkins PM,Harrison SM

更新日期：2004-04-01 00:00:00

abstract：UNLABELLED:Brain dysfunction after cardiopulmonary bypass (CPB) is common, and it has been hypothesized that this injury might be due partly to activation of inflammatory processes in the brain. We measured juguloarterial gradients for interleukin-1beta, interleukin-6, and interleukin-8 (IL-8) as indices of local proin...

journal_title：Anesthesia and analgesia

authors： Nandate K,Vuylsteke A,Crosbie AE,Messahel S,Oduro-Dominah A,Menon DK

更新日期：1999-10-01 00:00:00

abstract：:This study was designed to measure the disappearance rate of indocyanine green (ICG) as an indicator of hepatic blood flow in elderly patients undergoing internal fixation of fractured neck of femur. All patients were aged 60-90 yr and were randomized to receive either spinal (n = 10) or isoflurane (n = 10) anesthesia...

journal_title：Anesthesia and analgesia

authors： Darling JR,Murray JM,Hainsworth AM,Trinick TR

更新日期：1994-04-01 00:00:00

abstract：:Although convective warming therapy is effective in preventing hypothermia in anesthetized patients, little is known concerning the potential risks of its use. Hence, this balanced cross-over study was designed to determine if the use of convective warming therapy increased the risk of wound contamination. For 4 h, ei...

journal_title：Anesthesia and analgesia

authors： Zink RS,Iaizzo PA

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Manikins are widely used in airway management training; however, simulation of realism and interpatient variability remains a challenge. We investigated whether cadavers embalmed with the novel Fix for Life (F4L) embalmment method are a suitable and realistic model for teaching 3 basic airway skills: facemas...

journal_title：Anesthesia and analgesia

authors： van Emden MW,Geurts JJ,Schober P,Schwarte LA

更新日期：2018-10-01 00:00:00

abstract：:The epidural administration of morphine and fentanyl delay the regression of sensory anesthesia in postoperative patients receiving epidural bupivacaine. This study was performed to determine any differential effects of two lipid-soluble opioids upon regression of sensory anesthesia during coadministration with epidur...

journal_title：Anesthesia and analgesia

authors： Ferrante FM,Fanciullo GJ,Grichnik KP,Vaisman J,Sacks GM,Concepcion MA

更新日期：1993-12-01 00:00:00

abstract：UNLABELLED:There is concern that the environment in which consent for anesthesia research is sought may be coercive. We therefore designed this study to determine the factors that parents consider in consenting to their child's participation in clinical anesthesia research. The study sample consisted of 246 parents who...

journal_title：Anesthesia and analgesia

authors： Tait AR,Voepel-Lewis T,Siewert M,Malviya S

更新日期：1998-01-01 00:00:00

abstract：UNLABELLED:We investigated the effect of epidural local anesthetic blockade on urinary substance P levels in five patients suffering from painful flare-ups of interstitial cystitis. Urine was collected in 24-h intervals commencing at the onset of an epidural bolus of 0.25% bupivacaine followed by maintenance epidural i...

journal_title：Anesthesia and analgesia

authors： Sukiennik A,Carr DB,Bonney I,Marchand JE,Wurm H,Sant GR

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Although the bronchodilatory actions of volatile anesthetics, such as halothane, isoflurane, and sevoflurane, have been well documented in previous studies, the properties of desflurane remain controversial. The aim of this study was to investigate the effects of desflurane at different concentrations and du...

journal_title：Anesthesia and analgesia

authors： Zhou J,Iwasaki S,Yamakage M

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Cardiac surgery for carcinoid heart disease is complicated by hemodynamic instability secondary to carcinoid crises, cardiovascular dysfunction, and blood loss. The safety of vasopressors and the benefit of aprotinin during concomitant octreotide administration are uncertain. METHODS:We reviewed the effects...

journal_title：Anesthesia and analgesia

authors： Weingarten TN,Abel MD,Connolly HM,Schroeder DR,Schaff HV

更新日期：2007-11-01 00:00:00

abstract：:This study was undertaken to compare desflurane with propofol anesthesia in outpatients undergoing peripheral orthopedic surgery. Data were combined from two institutions participating in a multicenter study. Ninety-one patients, ASA physical status I or II, were each randomly assigned to one of four groups. After adm...

journal_title：Anesthesia and analgesia

authors： Rapp SE,Conahan TJ,Pavlin DJ,Levy WJ,Hautman B,Lecky J,Luke J,Nessly ML

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:In this prospective, randomized, observer-blinded trial, we compared ultrasound-guided subparaneural popliteal sciatic nerve blocks performed either at or proximal to the neural bifurcation (B). We hypothesized that the total anesthesia-related time (sum of performance and onset times) would be decreased wit...

journal_title：Anesthesia and analgesia

authors： Tran DQ,González AP,Bernucci F,Pham K,Finlayson RJ

更新日期：2013-05-01 00:00:00

abstract：:We measured arterial plasma concentrations of lidocaine by enzyme immunoassay when 10 ml of 2% lidocaine without epinephrine was injected into the cervical, thoracic, or lumbar epidural spaces in 30 patients. There was no difference in the time courses of plasma levels of lidocaine. Peak concentrations were achieved 1...

journal_title：Anesthesia and analgesia

authors： Mayumi T,Dohi S,Takahashi T

更新日期：1983-06-01 00:00:00