A randomized comparison between bifurcation and prebifurcation subparaneural popliteal sciatic nerve blocks.


BACKGROUND:In this prospective, randomized, observer-blinded trial, we compared ultrasound-guided subparaneural popliteal sciatic nerve blocks performed either at or proximal to the neural bifurcation (B). We hypothesized that the total anesthesia-related time (sum of performance and onset times) would be decreased with the prebifurcation (PB) technique. METHODS:Ultrasound-guided posterior popliteal sciatic nerve block was performed in 68 patients. All subjects received an identical volume (30 mL) and mix of local anesthetic agent (1% lidocaine-0.25% bupivacaine-5 µg/mL epinephrine). In the PB group, the local anesthetic solution was deposited at the level of the common sciatic trunk, just distal to the intersection between its circular and elliptical sonographic appearances, inside the paraneural sheath. In the B group, the injection was performed inside the sheath between the tibial and peroneal divisions. A blinded observer recorded the success rate (complete tibial and peroneal sensory block at 30 minutes) and onset time. The performance time, number of needle passes, and adverse events (paresthesia, neural edema) were also recorded. All subjects were contacted 7 days after the surgery to inquire about the presence of persistent numbness or motor deficit. RESULTS:Both techniques resulted in comparable success rates (85%-88%; 95% confidence interval [CI] of the intergroup difference, -14% to 19%) and required similar performance times (8.1 minutes; 95% CI of the difference, -1.65 to 1.71 minutes), onset times (15.0-17.7 minutes; 95% CI of the difference, -7.65 to 2.31 minutes), and total anesthesia-related times (23.4-26.0 minutes; 95% CI of the difference, -7.83 to 2.74 minutes). The number of needle passes and incidence of paresthesia (25%-34%) were also similar between the 2 groups. Sonographic neural swelling was detected in 2 and 3 subjects in the PB and B groups, respectively. In all 5 cases, the needle was carefully withdrawn and the injection completed uneventfully. Patient follow-up 1 week after the surgery revealed 2 patients with residual numbness. In both instances, the latter had resolved by 1 month. CONCLUSION:When local anesthetic is injected inside the paraneural sheath, B and PB posterior popliteal sciatic nerve blocks result in comparable success and total anesthesia-related times. However, in light of the 95% CIs, we cannot exclude the possibility that an intergroup difference of 19% and 7.83 minutes might have gone undetected for success rate and total time, respectively.


Anesth Analg


Anesthesia and analgesia


Tran DQ,González AP,Bernucci F,Pham K,Finlayson RJ




Has Abstract


2013-05-01 00:00:00














  • Dose-response of remifentanil for tracheal intubation in infants.

    abstract::To compare the dose-response of remifentanil for tracheal intubation in infants and children, 32 healthy full-term infants and 32 children were anesthetized with 10 mug/kg glycopyrrolate and 4.0 mg/kg propofol and administered 1 of 4 doses of remifentanil (1.25, 1.50, 1.75, or 2.00 microg/kg) to facilitate tracheal in...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Crawford MW,Hayes J,Tan JM

    更新日期:2005-06-01 00:00:00

  • A comparison of costs and efficacy of ondansetron and droperidol as prophylactic antiemetic therapy for elective outpatient gynecologic procedures.

    abstract::Ondansetron and droperidol are both effective prophylactic antiemetics for gynecologic outpatient procedures. However, increased drowsiness, delayed discharge, and postdischarge restlessness may occur with droperidol, and ondansetron is costly. In this prospective, randomized, double-blind, placebo-controlled study in...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Tang J,Watcha MF,White PF

    更新日期:1996-08-01 00:00:00

  • Hepatic circulation during surgical stress and anesthesia with halothane, isoflurane, or fentanyl.

    abstract::Hepatic blood flow and the oxygen supply/uptake relation were studied in 19 miniature pigs using labeled microspheres. Changes in hepatic arterial blood flow and portal blood flow, as well as total hepatic blood flow during halothane anesthesia were more closely associated with changes in mean arterial pressure (MAP) ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Gelman S,Dillard E,Bradley EL Jr

    更新日期:1987-10-01 00:00:00

  • Exhaled Propofol Concentrations Correlate With Plasma and Brain Tissue Concentrations in Rats.

    abstract:BACKGROUND:Propofol can be measured in exhaled gas. Exhaled and plasma propofol concentrations correlate well, but the relationship with tissue concentrations remains unknown. We thus evaluated the relationship between exhaled, plasma, and various tissue propofol concentrations. Because the drug acts in the brain, we f...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Müller-Wirtz LM,Maurer F,Brausch T,Kiefer D,Floss M,Doneit J,Volk T,Sessler DI,Fink T,Lehr T,Kreuer S

    更新日期:2021-01-01 00:00:00

  • Transesophageal echocardiography in myocardial revascularization: I. Accuracy of intraoperative real-time interpretation.

    abstract::Transesophageal echocardiography (TEE) is increasingly used intraoperatively as a monitor of ventricular function and volume. Despite its increasing use, whether data from TEE monitoring can be interpreted accurately on-line in real-time is unknown. We studied the performance of five community-based, full-time cardiac...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章


    authors: Bergquist BD,Leung JM,Bellows WH

    更新日期:1996-06-01 00:00:00

  • Noninfectious Fever in the Near-Term Pregnant Rat Induces Fetal Brain Inflammation: A Model for the Consequences of Epidural-Associated Maternal Fever.

    abstract:BACKGROUND:Women laboring with epidural analgesia experience fever much more frequently than do women who chose other forms of analgesia, and maternal intrapartum fever is associated with numerous adverse consequences, including brain injury in the fetus. We developed a model of noninfectious inflammatory fever in the ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Segal S,Pancaro C,Bonney I,Marchand JE

    更新日期:2017-12-01 00:00:00

  • The effects of pyrilamine and cimetidine on mRNA C-fos expression and nociceptive flinching behavior in rats.

    abstract:UNLABELLED:C-fos and Fos expression, frequently used as a neural nociceptive marker, is altered by many drugs. The effects of histamine receptor antagonists on c-fos messenger (m)RNA expression are unknown. We examined the effect of local and systemic administration of pyrilamine (H(1) receptor antagonist) and cimetidi...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Ashmawi HA,Chambergo FS,Araújo Palmeira CC,de Paula Posso I

    更新日期:2003-08-01 00:00:00

  • The effect of outpatient preoperative evaluation of hospital inpatients on cancellation of surgery and length of hospital stay.

    abstract:UNLABELLED:To evaluate the possible effects of outpatient preoperative evaluation (OPE) for new surgical patients who will be inpatients, we conducted an observational study at a university hospital in The Netherlands. Various outcomes before and after the introduction of an OPE clinic were compared. The study populati...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: van Klei WA,Moons KG,Rutten CL,Schuurhuis A,Knape JT,Kalkman CJ,Grobbee DE

    更新日期:2002-03-01 00:00:00

  • Comparative myocardial depression of sevoflurane, isoflurane, and halothane in cultured neonatal rat ventricular myocytes.

    abstract:UNLABELLED:In this study, we compared the direct myocardial depressant effects of sevoflurane, isoflurane, and halothane and determined whether an L-type Ca2+ channel agonist, Bay K 8644, could attenuate the myocardial depression induced by these anesthetics in cultured neonatal rat ventricular myocytes. Ventricular my...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Kanaya N,Kawana S,Tsuchida H,Miyamoto A,Ohshika H,Namiki A

    更新日期:1998-11-01 00:00:00

  • Improved clot formation by combined administration of activated factor VII (NovoSeven) and fibrinogen (Haemocomplettan P).

    abstract:BACKGROUND:Recombinant activated factor VII (rFVIIa) is increasingly used for treating refractory bleeding after cardiac surgery. However, hemostasis also depends on coagulation factors, including fibrinogen, which stabilizes platelet plugs at sites of vascular injury. We compared the hemostatic effects of rFVIIa, fibr...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Tanaka KA,Taketomi T,Szlam F,Calatzis A,Levy JH

    更新日期:2008-03-01 00:00:00

  • Preoperative Salivary Cortisol AM/PM Ratio Predicts Early Postoperative Cognitive Dysfunction After Noncardiac Surgery in Elderly Patients.

    abstract:BACKGROUND:The diagnosis of postoperative cognitive dysfunction (POCD) requires complicated neuropsychological testing and is often delayed. Possible biomarkers for early detection or prediction are essential for the prevention and treatment of POCD. Preoperative screening of salivary cortisol levels may help to identi...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Han Y,Han L,Dong MM,Sun QC,Zhang ZF,Ding K,Zhang YD,Mannan A,Xu YF,Ou-Yang CL,Li ZY,Gao C,Cao JL

    更新日期:2019-02-01 00:00:00

  • A comparison of intranasal dexmedetomidine and oral midazolam for premedication in pediatric anesthesia: a double-blinded randomized controlled trial.

    abstract:BACKGROUND:Midazolam is the most commonly used premedication in children. It has been shown to be more effective than parental presence or placebo in reducing anxiety and improving compliance at induction of anesthesia. Clonidine, an alpha(2) agonist, has been suggested as an alternative. Dexmedetomidine is a more alph...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,随机对照试验


    authors: Yuen VM,Hui TW,Irwin MG,Yuen MK

    更新日期:2008-06-01 00:00:00

  • Comparison of Thrombelastography-Derived Fibrinogen Values at Rewarming and Following Cardiopulmonary Bypass in Cardiac Surgery Patients.

    abstract:BACKGROUND:The inflated costs and documented deleterious effects of excess perioperative transfusion have led to the investigation of targeted coagulation factor replacement strategies. One particular coagulation factor of interest is factor I (fibrinogen). Hypofibrinogenemia is typically tested for using time-consumin...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章


    authors: Fabbro M 2nd,Gutsche JT,Miano TA,Augoustides JG,Patel PA

    更新日期:2016-09-01 00:00:00

  • GABA(A) receptor blockade antagonizes the immobilizing action of propofol but not ketamine or isoflurane in a dose-related manner.

    abstract:UNLABELLED:The enhancing action of propofol on gamma-amino-n-butyric acid subtype A (GABA(A)) receptors purportedly underlies its anesthetic effects. However, a recent study found that a GABA(A) antagonist did not alter the capacity of propofol to depress the righting reflex. We examined whether the noncompetitive GABA...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Sonner JM,Zhang Y,Stabernack C,Abaigar W,Xing Y,Laster MJ

    更新日期:2003-03-01 00:00:00

  • The Efficacy of Eslicarbazepine Acetate in Models of Trigeminal, Neuropathic, and Visceral Pain: The Involvement of 5-HT1B/1D Serotonergic and CB1/CB2 Cannabinoid Receptors.

    abstract:BACKGROUND:Many clinical pain states that are difficult to treat share a common feature of sensitization of nociceptive pathways. Drugs that could normalize hyperexcitable neural activity (e.g., antiepileptic drugs) may be useful in relieving these pain states. Eslicarbazepine acetate (ESL) is a novel antiepileptic dru...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Tomić MA,Pecikoza UB,Micov AM,Stepanović-Petrović RM

    更新日期:2015-12-01 00:00:00

  • Reliability of the transient hyperemic response test in detecting changes in cerebral autoregulation induced by the graded variations in end-tidal carbon dioxide.

    abstract:UNLABELLED:The transient hyperemic response (THR) in the middle cerebral artery (MCA) after the release of brief compression of the ipsilateral common carotid artery has been used to study cerebral autoregulation. We conducted the present study to evaluate the reliability of THR to detect changes in cerebral autoregula...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Mahajan RP,Cavill G,Simpson EJ

    更新日期:1998-10-01 00:00:00

  • Clinical uses of the Bonfils Retromolar Intubation Fiberscope: a review.

    abstract::The Bonfils Retromolar Intubation Fiberscope is a rigid, straight fiberoptic device with a 40-degree curved tip, which facilitates targeted intubation. Bonfils, using a retromolar approach to intubate tracheas of children with Pierre Robin syndrome, was first described in 1983. After an initial steep learning curve, t...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,评审


    authors: Thong SY,Wong TG

    更新日期:2012-10-01 00:00:00

  • Barbiturate-benzodiazepine interactions at the gamma-aminobutyric acidA receptor in rat cerebral cortical synaptoneurosomes.

    abstract::Combinations of benzodiazepines (midazolam and diazepam) with barbiturates (pentobarbital and phenobarbital) exhibit synergistic (supra-additive) hypnotic interactions in rats. Because both benzodiazepines and barbiturates interact with the gamma-aminobutyric acidA (GABAA) receptor complex, we have tested the hypothes...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: DeLorey TM,Kissin I,Brown P,Brown GB

    更新日期:1993-09-01 00:00:00

  • A comparison of two epidural alpha 2-agonists, guanfacine and clonidine, in regard to duration of antinociception, and ventilatory and hemodynamic effects in goats.

    abstract::Epidural clonidine produces analgesia in humans with acute and chronic pain. Its use is limited because of short-lasting analgesia, hemodynamic depression, sedation, and respiratory depression. Intrathecal guanfacine has a longer duration of action than intrathecal clonidine. The present study compares these two drugs...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Smith BD,Baudendistel LJ,Gibbons JJ,Schweiss JF

    更新日期:1992-05-01 00:00:00

  • Differential changes of alveolar gas concentrations during anesthetic induction of a patient with an absent right pulmonary artery.

    abstract::A 38-yr-old man with congenital right pulmonary artery agenesis, whose right lung was perfused with collateral systemic arterial blood, presented for right pneumonectomy. Because of a likely difference in gas exchange between the two lungs, we sampled end-tidal gases from each lung individually, as well as from the co...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Jiang Y,Wain JC,Chang AW,Zapol WM,Xie Z

    更新日期:2006-08-01 00:00:00

  • Capturing Essential Information to Achieve Safe Interoperability.

    abstract::In this article, we describe the role of "clinical scenario" information to assure the safety of interoperable systems, as well as the system's ability to deliver the requisite clinical functionality to improve clinical care. Described are methods and rationale for capturing the clinical needs, workflow, hazards, and ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Weininger S,Jaffe MB,Rausch T,Goldman JM

    更新日期:2017-01-01 00:00:00

  • American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Patient-Reported Outcomes in an Enhanced Recovery Pathway.

    abstract::Patient-reported outcomes (PROs) are measures of health status that come directly from the patient. PROs are an underutilized tool in the perioperative setting. Enhanced recovery pathways (ERPs) have primarily focused on traditional measures of health care quality such as complications and hospital length of stay. The...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,评审


    authors: Abola RE,Bennett-Guerrero E,Kent ML,Feldman LS,Fiore JF Jr,Shaw AD,Thacker JKM,Gan TJ,Miller TE,Hedrick TL,McEvoy MD,Mythen MG,Bergamaschi R,Gupta R,Holubar SD,Senagore AJ,Wischmeyer PE,Carli F,Evans DC,Guilbert S,

    更新日期:2018-06-01 00:00:00

  • Takuo Aoyagi: discovery of pulse oximetry.

    abstract::In the 1930s and 1940s, photo cells permitted German, English, and American physiologists to construct ear oximeters with red and infrared light, requiring calibration. In 1940 Squire recognized that changes of red and infrared light transmission caused by pneumatic tissue compression permitted saturation to be comput...

    journal_title:Anesthesia and analgesia

    pub_type: 传,历史文章,杂志文章


    authors: Severinghaus JW

    更新日期:2007-12-01 00:00:00

  • Exposure to sevoflurane and nitrous oxide during four different methods of anesthetic induction.

    abstract:UNLABELLED:The National Institute for Occupational Safety and Health-recommended exposure levels for nitrous oxide exposure are 25 ppm as a time-weighted average over the time of exposure. The exposure limit for halogenated anesthetics (without concomitant nitrous oxide exposure) is 2 ppm. Inhaled sevoflurane provides ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Hoerauf KH,Wallner T,Akça O,Taslimi R,Sessler DI

    更新日期:1999-04-01 00:00:00

  • Preemptive and Preventive Pain Psychoeducation and Its Potential Application as a Multimodal Perioperative Pain Control Option: A Systematic Review.

    abstract::The common treatment for postoperative pain is prescription opioids. Yet, these drugs have limited effect in preventing chronic pain from surgical intervention and have in part contributed to the opioid epidemic. Recently, preemptive analgesia and multimodal analgesia have been proposed with widely gained acceptance i...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Horn A,Kaneshiro K,Tsui BCH

    更新日期:2020-03-01 00:00:00

  • The feasibility of patient-controlled paravertebral analgesia for major breast cancer surgery: a prospective, randomized, double-blind comparison of two regimens.

    abstract:BACKGROUND:Paravertebral analgesia is useful for breast surgery. Patient controlled analgesia by IV or epidural routes is well established for delivering postoperative analgesia. Our objective was to apply patient control to paravertebral analgesia and evaluate the efficacy and tolerability of two distinct dosing regim...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,随机对照试验


    authors: McElwain J,Freir NM,Burlacu CL,Moriarty DC,Sessler DI,Buggy DJ

    更新日期:2008-08-01 00:00:00

  • Altered response to formalin by L5 spinal nerve ligation in rats: a behavioral and molecular study.

    abstract:BACKGROUND:The status of neuropathic pain alters the responsiveness to formalin injection in rats. However, the mechanism by which this alteration occurs is unknown. METHODS:We used immunocytochemistry to examine the expression of brain-derived neurotrophic factor (BDNF) and calcitonin gene-related peptide (CGRP) in t...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Kaku R,Yokoyama M,Kobayashi H,Matsuoka Y,Sato T,Mizobuchi S,Itano Y,Morita K

    更新日期:2007-04-01 00:00:00

  • Dexamethasone added to lidocaine prolongs axillary brachial plexus blockade.

    abstract::Different additives have been used to prolong regional blockade. We designed a prospective, randomized, double-blind study to evaluate the effect of dexamethasone added to lidocaine on the onset and duration of axillary brachial plexus block. Sixty patients scheduled for elective hand and forearm surgery under axillar...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,随机对照试验


    authors: Movafegh A,Razazian M,Hajimaohamadi F,Meysamie A

    更新日期:2006-01-01 00:00:00

  • Bisulfite-containing propofol: is it a cost-effective alternative to Diprivan for induction of anesthesia?

    abstract:UNLABELLED:Propofol (Diprivan(TM); AstraZeneca, Wilmington, DE) is a commonly used drug for the induction of general anesthesia in the ambulatory setting. With the availability of a new bisulfite-containing generic formulation of propofol, questions have arisen regarding its cost effectiveness and safety compared with ...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Shao X,Li H,White PF,Klein KW,Kulstad C,Owens A

    更新日期:2000-10-01 00:00:00

  • Effects of patient age, pH of cerebrospinal fluid, and vasopressors on onset and duration of spinal anesthesia.

    abstract::Two hundred twenty-two spinal anesthesias were administered with 10 mg. of tetracaine and 1 ml. of 10 percent dextrose to investigate the effects of vasopressors, patients age, and pH of cerebrospinal fluid on the onset and duration of spinal anesthesia. Neither the differences in overall age, cerebrospinal fluid pH, ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Park WY,Balingit PE,Macnamara TE

    更新日期:1975-07-01 00:00:00