Effects of sodium pentobarbital, ketamine, halothane, and chloralose on brainstem auditory evoked responses.

abstract：UNLABELLED:Adhesion of polymorphonuclear neutrophils (PMN) to the coronary endothelium is a crucial step in the development of ischemic myocardial injury. We tested the possible effects of six widely used IV anesthetics on non- and postischemic coronary adhesion of PMN in isolated perfused guinea pig hearts. Hearts (n ...

journal_title：Anesthesia and analgesia

authors： Szekely A,Heindl B,Zahler S,Conzen PF,Becker BF

更新日期：2000-06-01 00:00:00

abstract：:Wound perfusion and oxygenation are important determinants of the development of postoperative wound infections. Supplemental fluid administration significantly increases tissue oxygenation in surrogate wounds in the subcutaneous tissue of the upper arm in perioperative surgical patients. We tested the hypothesis that...

journal_title：Anesthesia and analgesia

authors： Kabon B,Akça O,Taguchi A,Nagele A,Jebadurai R,Arkilic CF,Sharma N,Ahluwalia A,Galandiuk S,Fleshman J,Sessler DI,Kurz A

更新日期：2005-11-01 00:00:00

abstract：UNLABELLED:To evaluate the efficacy and acceptance of a new posterior subgluteus approach to the sciatic nerve, as compared with the classic posterior approach, 128 patients undergoing foot orthopedic procedures were randomly allocated to receive either the classic posterior sciatic nerve block (Group Labat, n = 64) or...

journal_title：Anesthesia and analgesia

authors： di Benedetto P,Bertini L,Casati A,Borghi B,Albertin A,Fanelli G

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:The therapeutic use of opioids has been associated with altered cognition and impaired psychomotor function. Several studies have demonstrated the impact of opioid therapy on psychomotor performance and cognition, but there are no data about the effect of long-term treatment with transdermal buprenorphine on...

journal_title：Anesthesia and analgesia

authors： Dagtekin O,Gerbershagen HJ,Wagner W,Petzke F,Radbruch L,Sabatowski R

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Among the various factors influencing the success rate, onset time, and duration of peripheral nerve blocks, the role of local anesthetics concentration remains uncertain. In this prospective, randomized, single-blinded study, we evaluated whether varying the dilution of a fixed dose of mepivacaine solution ...

journal_title：Anesthesia and analgesia

authors： Cappelleri G,Ambrosoli AL,Turconi S,Gemma M,Ricci EB,Cornaggia G

更新日期：2014-08-01 00:00:00

abstract：:Single channel recordings have shown that ketamine (Ket) decreases the open time of the nicotinic acetylcholine receptor channel (nAChR). The present experiments on simultaneous openings of the nAChRs of mouse myotubes investigate the interaction of Ket with the open as well as with the closed state of the channels. T...

journal_title：Anesthesia and analgesia

authors： Scheller M,Bufler J,Hertle I,Schneck HJ,Franke C,Kochs E

更新日期：1996-10-01 00:00:00

abstract：:The application of digital pressure above the injection site during interscalene block has been advocated to prevent cephalad spread of local anesthetic. In prior studies, radiographs taken immediately after interscalene injection of radiographic contrast have supported this concept. However, the clinical efficacy of ...

journal_title：Anesthesia and analgesia

authors： Urmey WF,Grossi P,Sharrock NE,Stanton J,Gloeggler PJ

更新日期：1996-08-01 00:00:00

abstract：UNLABELLED:We performed in vitro studies to investigate the potential interaction of benzodiazepines with cloned human opioid receptor subtypes. Midazolam, chlordiazepoxide, and diazepam directly displaced [(3)H]-diprenorphine binding from kappa and delta receptors, but not mu receptors, whereas flumazenil was inactive...

journal_title：Anesthesia and analgesia

authors： Cox RF,Collins MA

更新日期：2001-08-01 00:00:00

abstract：UNLABELLED:Carpal tunnel release is often performed as an outpatient procedure. We designed this retrospective study to assess the effect of different anesthesia techniques on intraoperative cardiovascular stability and discharge time. According to the anesthesia technique received, 62 consecutive patients were categor...

journal_title：Anesthesia and analgesia

authors： Gebhard RE,Al-Samsam T,Greger J,Khan A,Chelly JE

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:We have recently shown that levetiracetam, administered systemically, exerts an antihyperalgesic effect in a rat inflammatory pain model. In this study, we examined whether levetiracetam has local peripheral antihyperalgesic/anti-edematous effects in the same model of localized inflammation and whether opioi...

journal_title：Anesthesia and analgesia

authors： Stepanović-Petrović RM,Micov AM,Tomić MA,Ugrešić ND

更新日期：2012-12-01 00:00:00

abstract：INTRODUCTION:Decompression illness (DCI) is caused by bubble formation in the blood or tissues after a reduction in ambient pressure. Clinically, DCI may range from a trivial illness to paralysis, loss of consciousness, cardiovascular collapse, and death. Recompression is the universally accepted standard for the treat...

journal_title：Anesthesia and analgesia

authors： Bennett MH,Lehm JP,Mitchell SJ,Wasiak J

更新日期：2010-09-01 00:00:00

abstract：:In this review, we summarize the clinical implications of residual neuromuscular block. Data suggest that residual neuromuscular block is a common complication in the postanesthesia care unit, with approximately 40% of patients exhibiting a train-of-four ratio <0.9. Volunteer studies have demonstrated that small degre...

journal_title：Anesthesia and analgesia

authors： Murphy GS,Brull SJ

更新日期：2010-07-01 00:00:00

abstract：:The purpose of these experiments was to analyze the cerebrovascular and cerebral metabolic effects of midazolam, a short-acting water-soluble benzodiazepine, and to investigate its interaction with alcohol in rats. A benzodiazepine antagonist, 3-carbo-t-butoxy-beta-carboline (beta-CCT), was used to test the role of th...

journal_title：Anesthesia and analgesia

authors： Van Gorder PN,Hoffman WE,Baughman V,Albrecht RF,Miletich DJ,Guzman F,Cook JM

更新日期：1985-02-01 00:00:00

abstract：BACKGROUND:Paravertebral analgesia is useful for breast surgery. Patient controlled analgesia by IV or epidural routes is well established for delivering postoperative analgesia. Our objective was to apply patient control to paravertebral analgesia and evaluate the efficacy and tolerability of two distinct dosing regim...

journal_title：Anesthesia and analgesia

authors： McElwain J,Freir NM,Burlacu CL,Moriarty DC,Sessler DI,Buggy DJ

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Long-term exposure to opiates induces tolerance to the analgesic effect. The neurobiological mechanism of this phenomenon is not completely clear. In this study, we evaluated the effects of central administration of minocycline (a tetracycline derivative) and riluzole (an antiglutamatergic drug) on morphine-...

journal_title：Anesthesia and analgesia

authors： Habibi-Asl B,Hassanzadeh K,Charkhpour M

更新日期：2009-09-01 00:00:00

abstract：UNLABELLED:In this retrospective cohort study, we compared adverse cardiac outcomes after noncardiac surgery among patients with prior percutaneous transluminal coronary angioplasty (PTCA), patients with nonrevascularized coronary artery disease (CAD), and normal controls. Inpatient hospital discharge abstracts from al...

journal_title：Anesthesia and analgesia

authors： Posner KL,Van Norman GA,Chan V

更新日期：1999-09-01 00:00:00

abstract：:With the recent rapid adoption of electronic medical records (EMRs), studies reporting results based on EMR data have become increasingly common. While analyzing data extracted from our EMR for a retrospective study, we identified various types of erroneous data entries. This report investigates the root causes of the...

journal_title：Anesthesia and analgesia

authors： Baier AW,Snyder DJ,Leahy IC,Patak LS,Brustowicz RM

更新日期：2017-09-01 00:00:00

abstract：:In vitro experiments using guinea pig tracheal smooth muscle were performed to compare the relaxant properties of procaine, lidocaine, and ketamine following contracture induced by histamine. Procaine produced a spasmolytic effect in a dose-related manner. In the doses tested, relaxation induced by procaine was more p...

journal_title：Anesthesia and analgesia

authors： Wanna HT,Gergis SD

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:Every facility that performs cases on holidays has in some way decided on its operating room (OR) and anesthesia staffing for holidays. Previous studies have not examined how best to calculate appropriate holiday staffing. METHODS:We analyzed weekend and holiday data from a university hospital. RESULTS:The...

journal_title：Anesthesia and analgesia

authors： Dexter F,Epstein RH

更新日期：2006-12-01 00:00:00

abstract：:Drug dosages, length of stay (LOS), and incidence of psychological side effects of fentanyl and nalbuphine were compared in a randomized, double-blind study using unpremedicated female day-surgery patients undergoing diagnostic laparoscopy. Patients received either fentanyl 1.5 micrograms/kg (F group; n = 142), low-do...

journal_title：Anesthesia and analgesia

authors： Garfield JM,Garfield FB,Philip BK,Earls F,Roaf E

更新日期：1987-12-01 00:00:00

abstract：:This study was undertaken to compare desflurane with propofol anesthesia in outpatients undergoing peripheral orthopedic surgery. Data were combined from two institutions participating in a multicenter study. Ninety-one patients, ASA physical status I or II, were each randomly assigned to one of four groups. After adm...

journal_title：Anesthesia and analgesia

authors： Rapp SE,Conahan TJ,Pavlin DJ,Levy WJ,Hautman B,Lecky J,Luke J,Nessly ML

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:Modulation of γ-aminobutyric acid type A receptors (GABAARs) by general anesthetics may contribute to their ability to produce amnesia. Receptors containing α5 subunits, which mediate tonic and slow synaptic inhibition, are co-localized with β3 and γ2 subunits in dendritic layers of the hippocampus and are s...

journal_title：Anesthesia and analgesia

authors： Burkat PM,Lor C,Perouansky M,Pearce RA

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:The cellular mechanisms underlying the sedative effect of general anesthetics are not completely understood. Accumulating evidence indicates that the ventrolateral preoptic area (VLPO) of the hypothalamus plays a critical role. The VLPO contains 2 major types of neurons, the noradrenalin-inhibited GABAergic ...

journal_title：Anesthesia and analgesia

authors： Liu YW,Zuo W,Ye JH

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:The status of neuropathic pain alters the responsiveness to formalin injection in rats. However, the mechanism by which this alteration occurs is unknown. METHODS:We used immunocytochemistry to examine the expression of brain-derived neurotrophic factor (BDNF) and calcitonin gene-related peptide (CGRP) in t...

journal_title：Anesthesia and analgesia

authors： Kaku R,Yokoyama M,Kobayashi H,Matsuoka Y,Sato T,Mizobuchi S,Itano Y,Morita K

更新日期：2007-04-01 00:00:00

abstract：:In a laboratory experiment, the expected analgesic action of 33% nitrous oxide was reversed by creating the expectancy of heightened awareness of bodily sensations. Pain threshold and tolerance of electrical tooth-pulp stimulation were significantly reduced. Results from a control study gave us a basis for comparison ...

journal_title：Anesthesia and analgesia

authors： Dworkin SF,Chen AC,LeResche L,Clark DW

更新日期：1983-12-01 00:00:00

abstract：:Changes in cardiac output in response to augmenting cardiac contractility, preload, and heart rate during enflurane anesthesia were examined in 12 open-chested dogs. Cardiac contractility was assessed by the slope of the end-systolic pressure-volume relation (Emax). Dobutamine (3, 6, and 9 micrograms.kg-1.min-1) was a...

journal_title：Anesthesia and analgesia

authors： Sato M,Hoka S,Arimura H,Ono K,Yoshitake J

更新日期：1991-11-01 00:00:00

abstract：:We investigated the characteristics of hypoxemic fetoplacental vasoconstriction (HFPV) in the dual perfused, single isolated human placental cotyledon. Fetal arterial blood pressures (FAP) were measured in four cotyledons (Group 1) equilibrated with 21% oxygen (O2), 5% carbon dioxide (CO2), and nitrogen (N2) [control]...

journal_title：Anesthesia and analgesia

authors： Ramasubramanian R,Johnson RF,Downing JW,Minzter BH,Paschall RL

更新日期：2006-08-01 00:00:00

abstract：:Sevoflurane appears to have several properties that make it an attractive alternative to the currently available anesthetics for outpatient anesthesia. The relative low solubility of sevoflurane, as well as an impressive lack of airway irritation, makes it a very useful anesthetic for inhalation induction of anesthesi...

journal_title：Anesthesia and analgesia

authors： Smith I,Nathanson MH,White PF

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:Intrathecal drug delivery is an efficient method to administer therapeutic molecules to the central nervous system. However, even with identical drug dosage and administration mode, the extent of drug distribution in vivo is highly variable and difficult to control. Different cerebrospinal fluid (CSF) pulsat...

journal_title：Anesthesia and analgesia

authors： Hsu Y,Hettiarachchi HD,Zhu DC,Linninger AA

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Percutaneous cricothyroidotomy may be a life-saving procedure in cannot intubate-cannot ventilate situations. In this study we compared the insertion times of a new indicator-guided cricothyroidotomy device and a wire-guided device in mannequins. METHODS:This study was a crossover trial comparing the insert...

journal_title：Anesthesia and analgesia

authors： Assmann NM,Wong DT,Morales E

更新日期：2007-07-01 00:00:00