Local GABA(A) receptor blockade reverses isoflurane's suppressive effects on thalamic neurons in vivo.

abstract：BACKGROUND:Postoperative nausea (PON) is a common complication of anesthesia and surgery. Antiemetic medication for higher-risk patients may reduce but does not reliably prevent PON. We examined aromatherapy as a treatment for patients experiencing PON after ambulatory surgery. Our primary hypothesis was that in compar...

journal_title：Anesthesia and analgesia

authors： Hunt R,Dienemann J,Norton HJ,Hartley W,Hudgens A,Stern T,Divine G

更新日期：2013-09-01 00:00:00

abstract：:In this article, we describe the role of "clinical scenario" information to assure the safety of interoperable systems, as well as the system's ability to deliver the requisite clinical functionality to improve clinical care. Described are methods and rationale for capturing the clinical needs, workflow, hazards, and ...

journal_title：Anesthesia and analgesia

authors： Weininger S,Jaffe MB,Rausch T,Goldman JM

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Sedation protocols, including the use of sedation scales and regular sedation stops, help to reduce the length of mechanical ventilation and intensive care unit stay. Because clinical assessment of depth of sedation is labor-intensive, performed only intermittently, and interferes with sedation and sleep, pr...

journal_title：Anesthesia and analgesia

authors： Haenggi M,Ypparila-Wolters H,Buerki S,Schlauri R,Korhonen I,Takala J,Jakob SM

更新日期：2009-09-01 00:00:00

abstract：:Cimetidine blunts the increase in cerebral blood flow (CBF) normally observed during hypoxia. It is important, therefore, to know whether other H2-blockers also affect the cerebral circulation adaptation to hypoxia. Cerebral blood flow was measured in 24 awake dogs after an intravenous injection of either saline (cont...

journal_title：Anesthesia and analgesia

authors： Audibert G,Saunier C,Hartemann D,Bigard O,Haberer JP

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:Manikins are widely used in airway management training; however, simulation of realism and interpatient variability remains a challenge. We investigated whether cadavers embalmed with the novel Fix for Life (F4L) embalmment method are a suitable and realistic model for teaching 3 basic airway skills: facemas...

journal_title：Anesthesia and analgesia

authors： van Emden MW,Geurts JJ,Schober P,Schwarte LA

更新日期：2018-10-01 00:00:00

abstract：:Acute respiratory distress syndrome (ARDS) is a significant cause of morbidity and mortality in the intensive care unit (ICU) and is characterized by lung epithelial and endothelial cell injury, with increased permeability of the alveolar-capillary membrane, leading to pulmonary edema, severe hypoxia, and difficulty w...

journal_title：Anesthesia and analgesia

authors： Lee LK,Medzikovic L,Eghbali M,Eltzschig HK,Yuan X

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:The cellular mechanisms underlying the sedative effect of general anesthetics are not completely understood. Accumulating evidence indicates that the ventrolateral preoptic area (VLPO) of the hypothalamus plays a critical role. The VLPO contains 2 major types of neurons, the noradrenalin-inhibited GABAergic ...

journal_title：Anesthesia and analgesia

authors： Liu YW,Zuo W,Ye JH

更新日期：2013-08-01 00:00:00

abstract：:Computer-based measuring of the level of sedation and hypnosis is difficult and has proven to be challenging. The electroencephalogram (EEG) has been proposed as a potential method. Response entropy (RE) and state entropy (SE) are multifactor, dimensionless parameters of a new technology of EEG monitoring, and we inve...

journal_title：Anesthesia and analgesia

authors： Litscher G

更新日期：2006-06-01 00:00:00

abstract：:In in vitro pharmacological experiments, determination of effective concentration values for various anesthetics depends on understanding the exact concentration of the drugs dissolved in physiological solutions. Actual anesthetic concentration may differ from expectations because of drug adsorption, absorption or oth...

journal_title：Anesthesia and analgesia

authors： Suzuki T,Uchida I,Mashimo T

更新日期：2005-02-01 00:00:00

abstract：UNLABELLED:Reduction of the inflammatory reaction with the use of heparin coating has been found during and after cardiopulmonary bypass (CPB). The question remains whether this reduced reaction also decreases the magnitude of CPB-induced pulmonary dysfunction. We therefore evaluated the effects of a heparin-coated cir...

journal_title：Anesthesia and analgesia

authors： de Vroege R,van Oeveren W,van Klarenbosch J,Stooker W,Huybregts MA,Hack CE,van Barneveld L,Eijsman L,Wildevuur CR

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:Volatile inhaled anesthetics exert a differential protective effect against bronchospasm development after cholinergic stimulation. However, their ability to inhibit the adverse respiratory consequences of an anaphylactic reaction after exposure to an allergen has not been characterized. We therefore compare...

journal_title：Anesthesia and analgesia

authors： Lele E,Petak F,Carnesecchi S,Virag K,Argiroffo CB,Habre W

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Risk of intraoperative hypothermia is relatively high in middle-aged and elderly patients undergoing curative resection of esophageal cancer, which may cause myocardial ischemia during the early postoperative period. The objective of this study was to compare aggressive or standard body temperature managemen...

journal_title：Anesthesia and analgesia

authors： Zhang Z,Xu M,Wu D,Zhang X,Wu J

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Various different interventions can be used to reduce surgical blood loss; however, there is no "gold standard" for accurately measuring the volume of perioperative blood loss, and this makes it difficult to assess the efficacy of these interventions. METHODS:We used data from a previous multicenter double-...

journal_title：Anesthesia and analgesia

authors： Lopez-Picado A,Albinarrate A,Barrachina B

更新日期：2017-07-01 00:00:00

abstract：UNLABELLED:We evaluated in a qualitative systematic review the effect of N-methyl-D-aspartate (NMDA) receptor antagonists on reducing postoperative pain and analgesic consumption beyond the clinical duration of action of the target drug (preventive analgesia). Randomized trials examining the use of an NMDA antagonist i...

journal_title：Anesthesia and analgesia

authors： McCartney CJ,Sinha A,Katz J

更新日期：2004-05-01 00:00:00

abstract：:In vitro experiments using guinea pig tracheal smooth muscle were performed to compare the relaxant properties of procaine, lidocaine, and ketamine following contracture induced by histamine. Procaine produced a spasmolytic effect in a dose-related manner. In the doses tested, relaxation induced by procaine was more p...

journal_title：Anesthesia and analgesia

authors： Wanna HT,Gergis SD

更新日期：1978-01-01 00:00:00

abstract：:Animal studies suggest that increased circulating estrogen and progesterone, and activation of the endorphin system cause prenancy-induced antinociceptive effects. Human studies have provided inconsistent results and have often lacked a nonpregnant control group. In this study, we compared sensitivity to experimental ...

journal_title：Anesthesia and analgesia

authors： Carvalho B,Angst MS,Fuller AJ,Lin E,Mathusamy AD,Riley ET

更新日期：2006-11-01 00:00:00

abstract：:We studied the effect of intravenous (IV) thiamylal or ketamine on the increases in serum myoglobin, creatine kinase (CK), and potassium induced by succinylcholine under halothane anesthesia. Ninety patients were divided into three groups. In Group O, succinylcholine (1.0 mg/kg) was administered after an the inhaled i...

journal_title：Anesthesia and analgesia

authors： Noguchi I,Sankawa H,Andou M

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:The diagnosis of myocardial infarction (MI) after noncardiac surgery has traditionally relied on using relatively insensitive contemporary cardiac troponin (cTn) assays. We hypothesized that using a recently introduced novel high-sensitivity cTnT (hscTnT) assay would increase the detection rate of perioperat...

journal_title：Anesthesia and analgesia

authors： Brown JC,Samaha E,Rao S,Helwani MA,Duma A,Brown F,Gage BF,Miller JP,Jaffe AS,Apple FS,Scott MG,Nagele P

更新日期：2017-11-01 00:00:00

abstract：:The relative safety of epidural catheter placement with subsequent heparinization has been well documented. However, what is the risk of neurologic sequelae in such patients who receive warfarin perioperatively? This study retrospectively evaluates the risk of spinal hematoma in patients receiving postoperative epidur...

journal_title：Anesthesia and analgesia

authors： Horlocker TT,Wedel DJ,Schlichting JL

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:Anesthesia care has been provided by diverse health professionals worldwide, but little is known about anesthesiologists' views about this. Using a survey, we sought the opinions of a group of Brazilian anesthesiologists regarding nitrous oxide/oxygen and oral minimal/moderate sedation performed by dentists....

journal_title：Anesthesia and analgesia

authors： Costa PS,Valadao WJ Jr,Costa LR

更新日期：2010-01-01 00:00:00

abstract：:Direct thrombin inhibitors are heparin alternatives for anticoagulation during cardiopulmonary bypass in patients with heparin-induced thrombocytopenia. We report a case of a large thrombus forming in the venous reservoir while using bivalirudin. We suggest that blood stasis associated with the full venous reservoir m...

journal_title：Anesthesia and analgesia

authors： Wong JK,Tian Y,Shuttleworth P,Caffarelli AD,Reitz BA,Mora-Mangano CT

更新日期：2010-09-01 00:00:00

abstract：:We obtained data on lecture practices from 100 of the 110 university-affiliated anesthesiology residency programs certified in the United States in 1988. Of these residency programs, 36% had a majority of their lectures before the operating room schedule began, 57% had no lectures at all in this early time slot, and 7...

journal_title：Anesthesia and analgesia

authors： Landers DF,Becker GL,Newland MC,Peters KR

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to determine whether mechanically ventilated trauma patients with a positive urine drug screen (UDS) for cocaine and/or amphetamines have different opioid analgesic and sedative requirements compared with similar patients with a negative drug screen for these stimulants. METHOD...

journal_title：Anesthesia and analgesia

authors： Kram B,Kram SJ,Sharpe ML,James ML,Kuchibhatla M,Shapiro ML

更新日期：2017-03-01 00:00:00

abstract：:One of the most prevalent symptoms after major surgery is pain. When postoperative pain treatment is unsatisfactory, it can lead to poor surgical recovery, decreased quality of life, and increased health care costs. Current analgesics, single or in combination, have limited efficacy due to low potency, limited duratio...

journal_title：Anesthesia and analgesia

authors： Cata JP,Gorur A,Yuan X,Berg NK,Sood AK,Eltzschig HK

更新日期：2020-06-01 00:00:00

abstract：:The importance of timely administration of antibiotics for prophylaxis of surgical site infections has led to pressure on anesthesiologists to administer antibiotics. We present a survey of members of the American Association of Clinical Directors designed to evaluate the role of the anesthesiologist in the selection ...

journal_title：Anesthesia and analgesia

authors： Warters RD,Szmuk P,Pivalizza EG,Gebhard RE,Katz J,Ezri T,American Association of Clinical Directors.

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:The k(e)(0) value is the first order rate constant determining the equilibration of drugs between plasma or end-tidal concentration and effect-site (e.g., brain) concentration. Parametric and semiparametric approaches have been used for estimating individual k(e)(0) values and describing the drug-response cu...

journal_title：Anesthesia and analgesia

authors： Ellerkmann RK,Bruhn J,Soehle M,Kehrer M,Hoeft A,Kreuer S

更新日期：2009-11-01 00:00:00

abstract：:To further investigate possible prolongation of the frequency-corrected QT interval (QTc interval) after administration of droperidol (DRO), we studied 40 surgical patients who were randomly assigned to one of three groups, receiving an intravenous (IV) injection of either 0.1 mg/kg (Group 1, n = 10), 0.175 mg/kg (Gro...

journal_title：Anesthesia and analgesia

authors： Lischke V,Behne M,Doelken P,Schledt U,Probst S,Vettermann J

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Tardiness from scheduled start times is a common source of frustration for both operating room (OR) personnel and patients. Factors that influence tardiness were quantified in a companion paper and have been used to develop interventions that have the potential for reducing tardiness. METHODS:Data from two ...

journal_title：Anesthesia and analgesia

authors： Wachtel RE,Dexter F

更新日期：2009-06-01 00:00:00

abstract：:Continuous positive airway pressure (CPAP) of 5 and 10 cm H2O applied to the nonventilated lung is effective in improving arterial oxygenation during one-lung ventilation (1-LV). The effectiveness of lower levels of CPAP on improving oxygenation, however, has not been reported, possibly because of limitations of previ...

journal_title：Anesthesia and analgesia

authors： Hogue CW Jr

更新日期：1994-08-01 00:00:00

abstract：:A new single injection procedure, the fascia iliaca compartment block, is described for blocking the femoral, lateral cutaneous, and obturator nerves. The technique consists of injecting a local anesthetic immediately behind the fascia iliaca at the union of the lateral with the two medial thirds of the inguinal ligam...

journal_title：Anesthesia and analgesia

authors： Dalens B,Vanneuville G,Tanguy A

更新日期：1989-12-01 00:00:00