Maximizing prediction probability PK as an alternative semiparametric approach to estimate the plasma effect-site equilibration rate constant ke0.

abstract：BACKGROUND:Sugammadex is a modified [gamma] cyclodextrin compound, which encapsulates rocuronium to provide for a rapid reversal of residual neuromuscular blockade. We tested the hypothesis that sugammadex would provide for a more rapid reversal of a moderately profound residual rocuronium-induced blockade than the com...

journal_title：Anesthesia and analgesia

authors： Sacan O,White PF,Tufanogullari B,Klein K

更新日期：2007-03-01 00:00:00

abstract：:To quantify the effects of succinylcholine at the laryngeal adductor muscles and the adductor pollicis, 17 adult patients were studied during propofol-fentanyl anesthesia. Train-of-four stimulation was applied to the ulnar nerve at the wrist and the recurrent laryngeal nerve at the notch of the thyroid cartilage. Lary...

journal_title：Anesthesia and analgesia

authors： Meistelman C,Plaud B,Donati F

更新日期：1991-09-01 00:00:00

abstract：:After Fontan repair in children, we performed a prospective, open-label study to evaluate the effect of amrinone on pulmonary vascular resistance (PVRI). Eight patients who underwent the Fontan repair had baseline arterial pressure, left atrial pressure, central venous pressure, and cardiac output measured postoperati...

journal_title：Anesthesia and analgesia

authors： Sorensen GK,Ramamoorthy C,Lynn AM,French J,Stevenson JG

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:The diagnosis of myocardial infarction (MI) after noncardiac surgery has traditionally relied on using relatively insensitive contemporary cardiac troponin (cTn) assays. We hypothesized that using a recently introduced novel high-sensitivity cTnT (hscTnT) assay would increase the detection rate of perioperat...

journal_title：Anesthesia and analgesia

authors： Brown JC,Samaha E,Rao S,Helwani MA,Duma A,Brown F,Gage BF,Miller JP,Jaffe AS,Apple FS,Scott MG,Nagele P

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:The switch from International Classification of Diseases, Ninth Revision, Clinical Modification to International Classification of Diseases, Tenth Revision, Procedure Coding System (ICD-10-PCS) for coding of inpatient procedures in the United States increased the number of procedural codes more than 19-fold,...

journal_title：Anesthesia and analgesia

authors： Epstein RH,Dexter F,O'Neill L

更新日期：2019-06-01 00:00:00

abstract：:Both clonidine, an alpha(2) agonist, and morphine, an opioid agonist, provide enhanced patient analgesia after arthroscopic knee surgery when administered via the intraarticular (IA) route. Clonidine potentiates morphine analgesia in the animal model. We designed this study to determine whether clonidine or morphine r...

journal_title：Anesthesia and analgesia

authors： Joshi W,Reuben SS,Kilaru PR,Sklar J,Maciolek H

更新日期：2000-05-01 00:00:00

abstract：:A double-blind study comparing four narcotic analgesics of different potencies, meperidine, morphine, fentanyl, and sufentanil, was performed on consenting patients undergoing general or orthopedic surgery under balanced anesthesia. Blood pressure, measured through an indwelling arterial catheter, was recorded continu...

journal_title：Anesthesia and analgesia

authors： Flacke JW,Bloor BC,Kripke BJ,Flacke WE,Warneck CM,Van Etten AP,Wong DH,Katz RL

更新日期：1985-09-01 00:00:00

abstract：BACKGROUND:Infusion of lipid emulsion has been shown to reverse lipophilic drug-induced cardiovascular collapse in laboratory models and humans. The effect of high dose lipid in nondrug-induced cardiac arrest is, however, uncertain. In a rabbit model of asphyxial pulseless electrical activity (PEA) we compared lipid au...

journal_title：Anesthesia and analgesia

authors： Harvey M,Cave G,Kazemi A

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:The goal of this study was to determine a set of timing, shape, and statistical features available through noninvasive monitoring of maternal electrocardiogram and photoplethysmography that identifies preeclamptic patients. METHODS:Pregnant women admitted to Labor and Delivery were monitored with pulse oxim...

journal_title：Anesthesia and analgesia

authors： Euliano TY,Michalopoulos K,Singh S,Gregg AR,Del Rio M,Vasilopoulos T,Johnson AM,Onkala A,Darmanjian S,Euliano NR,Ho M

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:The vitalHEAT vH(2) (Dynatherm Medical, Inc., Fremont, California) system transfers heat through a single extremity using a combination of conductive heat (circulating warm water within soft fluid pads) with mild vacuum, which improves both vasodilation and contact between the heating element and the skin su...

journal_title：Anesthesia and analgesia

authors： Ruetzler K,Kovaci B,Güloglu E,Kabon B,Fleischmann E,Kurz A,Mascha E,Dietz D,Remzi F,Sessler DI

更新日期：2011-03-01 00:00:00

abstract：:Mitral valve replacement is frequently complicated by a low cardiac output syndrome and elevated pulmonary arterial pressures. In the present study, we used dobutamine to increase cardiac index and measured the pulmonary hemodynamic effects in 10 patients with increased pulmonary vascular tone following mitral valve r...

journal_title：Anesthesia and analgesia

authors： Schwenzer KJ,Miller ED Jr

更新日期：1989-04-01 00:00:00

abstract：:In this prospective randomized, double-blind study, we investigated the effect of ondansetron on the lidocaine subarachnoid block. Fifty-four male patients scheduled for transurethral surgery under subarachnoid anesthesia received oral ondansetron 4 mg the evening before surgery and 4 mg IV 15 min before subarachnoid ...

journal_title：Anesthesia and analgesia

authors： Fassoulaki A,Melemeni A,Zotou M,Sarantopoulos C

更新日期：2005-06-01 00:00:00

abstract：:A study of the effects of halothane on the cyclic 3',5'-adenosine monophosphate (cAMP) system in human platelets was undertaken since cAMP has been implicated in the regulation of the process of platelet aggregation and this anesthetic has been reported to decrease platelet aggregation and, in other tissues, to increa...

journal_title：Anesthesia and analgesia

authors： Walter F,Vulliemoz Y,Verosky Y,Triner L

更新日期：1980-11-01 00:00:00

abstract：:Qualitative arterial waveform analysis has been in existence for millennia; quantitative arterial waveform analysis techniques, which can be traced back to Euler's work in the 18th century, have not been widely used by anesthesiologists and other clinicians. This is likely attributable, in part, to the widespread use ...

journal_title：Anesthesia and analgesia

authors： Thiele RH,Durieux ME

更新日期：2011-10-01 00:00:00

abstract：:The application of digital pressure above the injection site during interscalene block has been advocated to prevent cephalad spread of local anesthetic. In prior studies, radiographs taken immediately after interscalene injection of radiographic contrast have supported this concept. However, the clinical efficacy of ...

journal_title：Anesthesia and analgesia

authors： Urmey WF,Grossi P,Sharrock NE,Stanton J,Gloeggler PJ

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:When temporary arterial occlusion of the parent artery is difficult for anatomical reasons, or when inadvertent aneurysmal rupture occurs during surgical dissection, adenosine administration can be used to produce flow arrest and brief, profound systemic hypotension that can facilitate intracranial aneurysm ...

journal_title：Anesthesia and analgesia

authors： Bebawy JF,Zeeni C,Sharma S,Kim ES,DeWood MS,Hemmer LB,Ramaiah VK,Bendok BR,Koht A,Gupta DK

更新日期：2013-11-01 00:00:00

abstract：:It remains questionable whether local anesthetics can interact with membrane lipids at clinically relevant concentrations to show the difference between enantiomers. We compared the effects of bupivacaine stereoisomers on biomimetic membranes containing cardiolipin and cholesterol. Bupivacaine interacted with the memb...

journal_title：Anesthesia and analgesia

authors： Tsuchiya H,Mizogami M

更新日期：2012-02-01 00:00:00

abstract：:A response algorithm consists of a logical sequence of maneuvers to be performed in response to a specific condition. With the advent of alarm-equipped monitors that alert anesthesiologists to the presence of potentially hazardous clinical conditions, a need has arisen to develop the corresponding alarm-oriented respo...

journal_title：Anesthesia and analgesia

authors： Raphael DT,Weller RS,Doran DJ

更新日期：1988-09-01 00:00:00

abstract：:Hemodynamic responses to physostigmine were evaluated in eight patients with coma due to overdose with mainly anticholinergic drugs (AC) and in five patients with coma due to overdose with nonanticholinergic drugs (NAC). After correction of hypovolemia, but before administration of physostigmine, AC patients had signi...

journal_title：Anesthesia and analgesia

authors： Nilsson E,Meretoja OA,Neuvonen P

更新日期：1983-10-01 00:00:00

abstract：:Quantitative Sensory Testing (QST) is a psycho-physiological test used to identify dysfunction of individual nerve fiber types. In the present study, we investigated whether selective nerve fiber dysfunction, as assessed by QST, correlates with the effectiveness of epidural steroid injections (ESI) in patients with lu...

journal_title：Anesthesia and analgesia

authors： Schiff E,Eisenberg E

更新日期：2003-09-01 00:00:00

abstract：:To investigate the possible role of atrial and brain natriuretic peptides (ANP and BNP) in the renal effects of mechanical ventilation with positive end-expiratory pressure (PEEP), we measured changes in plasma ANP and BNP levels during PEEP in patients undergoing subtotal esophagectomy. Application of 15 cm of H2O PE...

journal_title：Anesthesia and analgesia

authors： Shirakami G,Magaribuchi T,Shingu K,Suga S,Tamai S,Nakao K,Mori K

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Sigma (sigma)-receptor agonists attenuate brain injury after experimental focal cerebral ischemia in several species. We tested the hypothesis that the potent, prototypical sigma(1)-receptor agonist, 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP), protects neurons by a mechanism involving the antiapoptotic pro...

journal_title：Anesthesia and analgesia

authors： Yang S,Bhardwaj A,Cheng J,Alkayed NJ,Hurn PD,Kirsch JR

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:Through the Australian and New Zealand Haemostasis Registry, we report on the Australian and New Zealand experience with recombinant activated factor VII (rFVIIa) in obstetric patients. METHODS:The role of rFVIIa for off-label indications, including trauma, cardiac surgery, and severe postpartum hemorrhage, ...

journal_title：Anesthesia and analgesia

authors： Phillips LE,McLintock C,Pollock W,Gatt S,Popham P,Jankelowitz G,Ogle R,Cameron PA,Australian and New Zealand Haemostasis Registry.

更新日期：2009-12-01 00:00:00

abstract：:In a laboratory experiment, the expected analgesic action of 33% nitrous oxide was reversed by creating the expectancy of heightened awareness of bodily sensations. Pain threshold and tolerance of electrical tooth-pulp stimulation were significantly reduced. Results from a control study gave us a basis for comparison ...

journal_title：Anesthesia and analgesia

authors： Dworkin SF,Chen AC,LeResche L,Clark DW

更新日期：1983-12-01 00:00:00

abstract：:We studied 60 children undergoing elective surgery to evaluate the effect of interactions between vecuronium and isoflurane or halothane on the potency and duration of neuromuscular blockade, as measured by electromyography. Vecuronium was first administered by a logarithm-based cumulative method (14, 22, 35, 56, 89 m...

journal_title：Anesthesia and analgesia

authors： Pittet JF,Melis A,Rouge JC,Morel DR,Gemperle G,Tassonyi E

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Visual estimation and gravimetric methods are commonly used to quantify the volume of blood loss during cesarean delivery (CD). However, the correlation between blood loss and post-CD hemoglobin (Hb) is poorly studied, and it is unclear whether the correlation varies according to how blood loss is measured. ...

journal_title：Anesthesia and analgesia

authors： Fedoruk K,Seligman KM,Carvalho B,Butwick AJ

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Perioperative respiratory adverse events (PRAEs) account for the major cause of morbidity and mortality in children undergoing general anesthesia. In our institutional clinical practice, we suspected that African American children experienced untoward respiratory events more frequently than other racial grou...

journal_title：Anesthesia and analgesia

authors： Tariq S,Syed M,Martin T,Zhang X,Schmitz M

更新日期：2018-07-01 00:00:00

abstract：:The brain is one of the most metabolically active organs in the body. The brain's high energy demand associated with wakefulness persists during rapid eye movement sleep, and even during non-rapid eye movement sleep, cerebral oxygen consumption is only reduced by 20%. The active bioenergetic state parallels metabolic ...

journal_title：Anesthesia and analgesia

authors： Benveniste H,Heerdt PM,Fontes M,Rothman DL,Volkow ND

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Gabapentin is an adjuvant analgesic and may enhance the spread of subarachnoid block. We investigated the effects of pretreatment with gabapentin on subarachnoid block characteristics and hemodynamics. METHODS:Seventy patients undergoing transurethral procedures under subarachnoid anesthesia with 2.2 mL of ...

journal_title：Anesthesia and analgesia

authors： Fassoulaki A,Chatziara V,Melemeni A,Zotou M,Sarantopoulos C

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Hypotension remains a frequent complication of spinal anesthesia, increasing the risk of nausea and vomiting, altered mental status, and aspiration. The aim of this systematic review and meta-analysis was to determine whether 5-hydroxytryptamine3 (5-HT3) receptor antagonists, administered before the initiati...

journal_title：Anesthesia and analgesia

authors： Heesen M,Klimek M,Hoeks SE,Rossaint R

更新日期：2016-10-01 00:00:00