Abstract：
:Pregnancy is marked by a state of hypomagnesaemia but not much is known about the effects of maternal magnesium deprivation on the fetus. The aim of this study was therefore to measure magnesium concentrations in human myometrial and placental tissues and in different body fluids during pregnancy and at term, using atomic absorption spectrophotometry. The magnesium concentration in umbilical cord blood was higher than in the maternal blood, supporting the existence of an active magnesium transport system. There was also a difference between the magnesium concentration in the amniotic fluid and that in the umbilical cord blood. The magnesium content of myometrium increased from the 32nd week of pregnancy, reaching its maximum level at the 37th week of gestation. Later there was significant decrease in magnesium level until the end of pregnancy. The magnesium content of placental tissue did not change up to the 30th week of pregnancy; however, it then decreased continuously during the last trimester. The significant improvement experienced in certain pathological conditions of pregnancy treatment with magnesium supports the existence of a magnesium deficit induced by pregnancy and the need for magnesium supplementation.
journal_name
Magnes Resjournal_title
Magnesium researchauthors
Lukácsi L,Lintner F,Gimes G,Zsolnai B,Somogyi Jsubject
Has Abstractpub_date
1993-03-01 00:00:00pages
47-52issue
1eissn
0953-1424issn
1952-4021journal_volume
6pub_type
杂志文章abstract：OBJECTIVES:To examine the cross-sectional associations between serum magnesium (Mg) and hyperuricemia (HU). METHODS:2904 subjects were included in this study. HU was defined as uric acid ≥416 μmol/L for the male population and ≥360 μmol/L for the female population. A multivariable logistic analysis model was applied t...
journal_title：Magnesium research
pub_type： 杂志文章
doi：10.1684/mrh.2015.0384
更新日期：2015-06-01 00:00:00
abstract：BACKGROUND:Changes in plasma matrix metalloproteinase 9 (MMP-9) concentrations and parallel changes in brain magnesium homeostasis have not been examined in cardiac surgery patients. The purpose of the present study was to analyse these relationships in patients undergoing coronary artery bypass surgery (CABG) with ext...
journal_title：Magnesium research
pub_type： 杂志文章
doi：10.1684/mrh.2010.0219
更新日期：2010-12-01 00:00:00
abstract：:Although magnesium (Mg) contents are different between breast milk and formula, few studies have investigated the blood Mg level in breast fed or formula fed preterm infants. We examined the influence of feeding type on serum Mg and whole blood ionized Mg (iMg) levels in preterm infants soon after birth. We included 1...
journal_title：Magnesium research
pub_type： 杂志文章
doi：10.1684/mrh.2019.0444
更新日期：2018-11-01 00:00:00
abstract：:Increased white blood cell counts or leukocytosis have been observed primarily in young rats fed diets extremely low in Mg (< 60 ppm) and high in phosphorus (0.5 % P). We investigated the influence that acute and moderate Mg deficiencies have on blood leukocytes at high and low dietary phosphorus levels. For four week...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2006-06-01 00:00:00
abstract：UNLABELLED:Magnesium (Mg) plays an important role in lymphocyte function. Low blood concentration of Mg may result in intralymphocyte imbalance and in turn may be associated with intensified apoptosis of peripheral blood lymphocytes. Due to its multistage character; extracorporeal circulation (ECC) may augment Mg disor...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2005-12-01 00:00:00
abstract：:Complex fermentable carbohydrates, such as inulin-type fructans have been shown to improve Mg2+ absorption in the hindgut and body stores. The mechanisms for this are not well understood. The newly identified transient receptor potential melastatin 6 and 7 (TRPM6 and TRPM7) channels have been shown to function in acti...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2008-12-01 00:00:00
abstract：:Intracellular total Mg2+ and free Mg2+ are compartmentalized between cell organelles and within the cytosol. Different values of [Mg2+]i in the cytosol of the same cell type were measured by various investigators. A main reason for the differences is the uncertainty of the dissociation constants used for the Mg furapt...
journal_title：Magnesium research
pub_type： 杂志文章,评审
doi：
更新日期：2006-12-01 00:00:00
abstract：:The study was designed to investigate the role of magnesium (Mg) pretreatment on reduced glutathione (GSH) levels in kidney, liver and testis of mice intoxicated with cadmium (Cd). Animals were divided into four groups: I--controls, II--Cd group: mice intoxicated with Cd, III--Mg+Cd group: mice given Mg 1 h before Cd,...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2007-09-01 00:00:00
abstract：:Sodium bicarbonate is used to treat metabolic acidosis, or to induce metabolic alkalosis in sick neonates. The aim of this study was to quantify the decrease in serum concentration of ionized magnesium ([Mg2+]) when sodium bicarbonate is added to neonatal serum in vitro. Sodium bicarbonate was added to 30 cord serum s...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2004-06-01 00:00:00
abstract：PURPOSE:Critically evaluate the experimental evidence and clinical trial outcomes as the basis for use of magnesium (Mg) supplements as therapy for calcium oxalate nephrolithiasis. MATERIALS AND METHODS:Literature search of MedLine and Web of Science through January 2005; articles cited in papers found by searches. R...
journal_title：Magnesium research
pub_type： 杂志文章,评审
doi：
更新日期：2005-06-01 00:00:00
abstract：:Hypomagnesaemia has been reported among patients undergoing hemodialysis (HD). Recently, a possible correlation between serum magnesium (Mg) and C-reactive protein (CRP) has been stressed. This correlation has been attributed to cytokine production and oxidative stress processes. In this study we aimed to determine th...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2008-09-01 00:00:00
abstract：:We have recently demonstrated in the guinea pig that preventive dietary magnesium supplement can significantly reduce impulse noise induced hearing loss by on average 18 dB. The purpose of the present study was to examine whether magnesium might also have a therapeutic effect on noise trauma. Anesthetized guinea pigs ...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2002-03-01 00:00:00
abstract：:Epidemiological studies of populations living in areas of low magnesium (Mg) intake have consistently shown a higher cardiovascular morbidity. Several hypotheses have been advanced to explain the cardioprotective properties of magnesium. Few studies, however, have analysed the relation of magnesium to haemostasis. The...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：1996-10-01 00:00:00
abstract：:Magnesium deficiency has been linked with cardiac arrhythmias and sudden cardiac death. Antiarrhythmic effects of intravenous magnesium in the patients who are not hypomagnesaemic were mainly demonstrated in the patients with acquired long QT syndrome. Parenteral administration should be considered in this type of ven...
journal_title：Magnesium research
pub_type： 杂志文章,评审
doi：
更新日期：1994-06-01 00:00:00
abstract：:Ninety-five patients with acute myocardial infarction were followed up for 6 months to 3 years (mean 25.4 months) in a preliminary study to compare the effects of intravenous magnesium (49 patients) with that of intravenous propranolol (44 patients) given immediately after admission to the intensive care unit. There w...
journal_title：Magnesium research
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1994-12-01 00:00:00
abstract：:The present study was performed to show the molecular identity of functionally characterized Mg transport pathways in rumen epithelial cells (REC) and to investigate the effects of extracellular [Mg] changes on their expression and activity. By using RT- PCR, Western blot, flow cytometry and immunocytochemistry, TRPM7...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2008-06-01 00:00:00
abstract：:To investigate the effects of sex hormones on bone histomorphometry, and bone density (BMD), 10 week old ovariectomized (OVX), orchiectomized (ORX), and sham-operated (SHAM) rats fed a moderately magnesium-deficient fructose diet were studied. One third of the OVX and ORX rats were injected with beta-oestradiol-3-benz...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：1996-03-01 00:00:00
abstract：:Traumatic brain injury (TBI) confers a major burden to Western society and effective treatments are urgently required to improve the long-term deficits that inflict TBI survivors. Depletion of intracellular Mg(2+) is a well-known phenomenon occurring after TBI and is associated with poor neurological outcome. However,...
journal_title：Magnesium research
pub_type： 杂志文章,评审
doi：10.1684/mrh.2009.0189
更新日期：2009-12-01 00:00:00
abstract：:The current study assessed the neuroprotective efficacy of magnesium using a FAST-Mag trial treatment protocol alone, and in combination with mild hypothermia, in Sprague Dawley rats subjected to permanent, middle cerebral artery occlusion (MCAO). Treatment with magnesium (MgSO4.7H2O) consisted of an intravenous loadi...
journal_title：Magnesium research
pub_type： 杂志文章
doi：10.1684/mrh.2013.0340
更新日期：2013-04-01 00:00:00
abstract：:In therapy it is known that the combination of vitamin B6 and magnesium is beneficial in the treatment of several forms of primary magnesium deficiency. The purpose of the present study was to investigate the effect of complex magnesium supplementation containing mineral bishofit solution (MgCl2 x 6H2O) and pyridoxine...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2002-12-01 00:00:00
abstract：:The interaction of magnesium ions with biomolecular species is fundamental to the regulation of many biological processes. A mathematical technique to investigate such interactions is described. The concept of a pseudo-formation curve is discussed and the relevance and applicability of such constructions to the study ...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：1992-06-01 00:00:00
abstract：:The aim of the present study was to determine the effect of an aerobic training on plasma and red blood cells' levels of magnesium, copper, selenium and zinc and on some oxidative stress parameters in a Down syndrome (DS) sample population. Sixteen young male adults with DS participated in the protocol. Among them, ei...
journal_title：Magnesium research
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1997-03-01 00:00:00
abstract：:Dependency on extracellular calcium influx in contractile response to noradrenaline has been investigated in the thoracic aorta isolated from dietary magnesium (Mg) deficient rats. Adult male Wistar rats were fed with a Mg deficient diet (0.001% Mg) for 30 days, together with control groups (0.07% Mg). The contractile...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：1989-09-01 00:00:00
abstract：:Adequate magnesium (Mg) levels play a vital role in membrane excitability, cell contractility and metabolism, being a key nutrient for sustaining appropriate muscular contraction and performance levels in athletes. Phase angle (PhA), assessed by bioimpedance analysis (BIA), has been reported to be positively associate...
journal_title：Magnesium research
pub_type： 杂志文章
doi：10.1684/mrh.2015.0389
更新日期：2015-07-01 00:00:00
abstract：:More and more studies are accumulating about COVID-19. Some aspects of the pathogenesis of the disease recall events occurring in Mg deficiency, such as a drop of T cells, increased plasma concentration of inflammatory cytokines, and endothelial dysfunction. We hypothesize that a low Mg status, which is rather common,...
journal_title：Magnesium research
pub_type： 杂志文章
doi：10.1684/mrh.2020.0465
更新日期：2020-05-01 00:00:00
abstract：:A common use for high doses of oral magnesium salts is to produce a laxative effect to treat constipation. In the intestinal lumen the poorly absorbable magnesium ions (and other ions such as sulphate) exert an osmotic effect and cause water to be retained in the intestinal lumen. This increases the fluidity of the in...
journal_title：Magnesium research
pub_type： 杂志文章,评审
doi：
更新日期：1996-06-01 00:00:00
abstract：:A tight coupling between ionic currents, intracellular Ca2+ homeostasis, cytosolic [ADP] and deltaG of ATP hydrolysis underlies the regulation of cardiac cell function. As more experimental detail on the biochemistry and biophysics of these complex processes and their interactions accumulates, the intuitive interpreta...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2008-03-01 00:00:00
abstract：:Ageing constitutes a risk factor for magnesium deficit. Primary magnesium deficit originates from two aetiological mechanisms: deficiency and depletion. Primary magnesium deficiency is due to insufficient magnesium intake. Dietary amounts of magnesium are marginal in the whole population whatever the age. Nutritional ...
journal_title：Magnesium research
pub_type： 杂志文章,评审
doi：
更新日期：1993-12-01 00:00:00
abstract：:We evaluated the effects of oral magnesium supplementation on plasma lipid concentrations in patients with non-insulin-dependent diabetes mellitus. Twenty-six persons with non-insulin-dependent diabetes mellitus received 4.5 g magnesium pidolate/d for one month, and 17 persons received placebo. Before and at the end o...
journal_title：Magnesium research
pub_type： 临床试验,杂志文章
doi：
更新日期：1994-03-01 00:00:00
abstract：:Idiopathic mitral valve prolapse (IMVP) is a widespread disease. IMVP may be latent, but most patients describe a great variety of symptoms. The clinical pictures of IMVP and of latent tetany are superimposed with regard to Mg deficit. IMVP appears as a late complication of latent tetany due to magnesium deficit (LTMD...
journal_title：Magnesium research
pub_type： 杂志文章,评审
doi：
更新日期：1988-12-01 00:00:00
