Abstract：
:The study was designed to investigate the role of magnesium (Mg) pretreatment on reduced glutathione (GSH) levels in kidney, liver and testis of mice intoxicated with cadmium (Cd). Animals were divided into four groups: I--controls, II--Cd group: mice intoxicated with Cd, III--Mg+Cd group: mice given Mg 1 h before Cd, and IV--Mg group: mice given only Mg. In acute time--response studies, the single oral dose of Cd was 20 mg Cd/kg b.w. and 40 mg Mg/kg b.w. GSH levels were determined after 4, 6, 12, 24, and 48 h. In subacute experiments, mice were given 10 mg Cd/kg b.w. orally every day and 20 mg Mg/kg b.w., and GSH content was determined in investigated organs after 1 and 2 weeks. Acute cadmium intoxication significantly decreased the GSH content in liver 4, 6 and 12 h after Cd administration and increased GSH in kidney after 12, 24 and 48 h, but did not cause significant GSH alterations in testis. Mg pretreatment reduced the observed changes of GSH content in kidney and liver. Subacute Cd intoxication induced diminished renal GSH levels compared with the controls while the increased GSH levels were observed in liver and testes after 2 weeks Cd treatment. Mg pretreatment was efficient in restoring renal and testis GSH levels towards the control group, but had no effect on hepatic GSH.
journal_name
Magnes Resjournal_title
Magnesium researchauthors
Djukić-Cosić D,Ninković M,Malicević Z,Matović V,Soldatović Dsubject
Has Abstractpub_date
2007-09-01 00:00:00pages
177-86issue
3eissn
0953-1424issn
1952-4021journal_volume
20pub_type
杂志文章abstract：:The complex pressure wave (blast) generated by some explosions causes pulmonary pathological changes which resemble the histological findings of the adult respiratory distress syndrome (ARDS). The development of indirect neurotrauma following experimental pulmonary blast injury has been shown previously. The purpose o...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：1995-09-01 00:00:00
abstract：UNLABELLED:Magnesium (Mg) plays an important role in lymphocyte function. Low blood concentration of Mg may result in intralymphocyte imbalance and in turn may be associated with intensified apoptosis of peripheral blood lymphocytes. Due to its multistage character; extracorporeal circulation (ECC) may augment Mg disor...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2005-12-01 00:00:00
abstract：:Drinking water (DW) is an important dietary source of magnesium. Israel has recently increased desalinated seawater (DSW) production for DW, but negligible magnesium content in DSW may pose a risk of hypomagnesemia and consequential adverse cardiovascular effects. Consecutive acute myocardial infarction (AMI) patients...
journal_title：Magnesium research
pub_type： 杂志文章
doi：10.1684/mrh.2019.0449
更新日期：2019-05-01 00:00:00
abstract：:The objective of this study was to examine the influence of the endothelium on the extracellular magnesium induced relaxation of basal tension in isolated aortas from both mineralocorticoid-salt (DOCA-salt) hypertensive and control normotensive Sprague Dawley male rats. After incubation in magnesium-free physiological...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：1992-12-01 00:00:00
abstract：:The goal of this review is to bring to the attention of the readership of Magnesium Research another facet of the importance of magnesium, i.e. magnesium-based biomaterials. A concise history of biomaterials and magnesium are thus presented. In addition, historical and current, clinical magnesium-based applications ar...
journal_title：Magnesium research
pub_type： 杂志文章,评审
doi：10.1684/mrh.2015.0375
更新日期：2014-10-01 00:00:00
abstract：:Serum and mononuclear cell magnesium content were determined in a cross-sectional study performed in four groups of hypertensive patients on chronic treatment with atenolol (n = 11), enalapril (n = 10), thiazide diuretics (n = 12), or enalapril + thiazides (n = 11). Our study shows that in patients treated with the th...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：1990-09-01 00:00:00
abstract：:The purpose of the research work was to study the influence of alpha-zearalenol on magnesium concentration in cellular subfractions of certain tissues of female rats and their progeny. Pregnant female rats received alpha-zearalenol at the doses of: 0.05, 0.5 or 1 mg x kg(-1) b.w. After delivery, brain, liver and kidne...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2003-06-01 00:00:00
abstract：:Our objective was to evaluate the effect of intravenous magnesium sulphate administration to patients with preterm labour on maternal serum and amniotic fluid IL-1beta, IL-6, IL-10 and TNFalpha concentrations. Thirty-six patients at 24-34 weeks of singleton gestation, who presented with contractions (> or = 8 in 60 mi...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2002-12-01 00:00:00
abstract：:The consequences of broad-scale alterations in magnesium (Mg2+) levels on learning and memory are poorly understood. We have recently demonstrated that adult male mice maintained on an Mg2+-deficient diet exhibit reduced conditional freezing behavior. The purpose of the present study was to determine if the detrimenta...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2007-03-01 00:00:00
abstract：:Adequate magnesium (Mg) levels play a vital role in membrane excitability, cell contractility and metabolism, being a key nutrient for sustaining appropriate muscular contraction and performance levels in athletes. Phase angle (PhA), assessed by bioimpedance analysis (BIA), has been reported to be positively associate...
journal_title：Magnesium research
pub_type： 杂志文章
doi：10.1684/mrh.2015.0389
更新日期：2015-07-01 00:00:00
abstract：:Magnesium (Mg) deficiency strongly affects muscle performance. In judo, many athletes often undergo impressive weight changes associated with severe dehydration. Common practices used by athletes to achieve a target weight can lead to Mg deficit. This study aimed to understand the impact of Mg changes on strength from...
journal_title：Magnesium research
pub_type： 杂志文章
doi：10.1684/mrh.2010.0217
更新日期：2010-09-01 00:00:00
abstract：:Age-related human neurodegenerative diseases are a major social and medical problem. It is therefore logical to take into consideration every theory with an overall approach to neurodegenerative diseases. This environmental proposal relies mainly on data concerning the Western Pacific amyotrophic lateral sclerosis-Par...
journal_title：Magnesium research
pub_type： 杂志文章,评审
doi：
更新日期：1997-12-01 00:00:00
abstract：:46 children, aged 2-6 years, with decreased magnesium concentrations in hair, were studied. Magnesium supplementation consisted of Asmag preparation for 3 months and multivitamin Multi-tabs preparation (containing magnesium, but without calcium) for the following 4 months. Control studies were performed again after 7 ...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2001-03-01 00:00:00
abstract：:We have recently demonstrated in the guinea pig that preventive dietary magnesium supplement can significantly reduce impulse noise induced hearing loss by on average 18 dB. The purpose of the present study was to examine whether magnesium might also have a therapeutic effect on noise trauma. Anesthetized guinea pigs ...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2002-03-01 00:00:00
abstract：:Magnesium (Mg) and nickel (Ni) are biologically active elements in higher animals. Recent studies in vivo as well as in vitro point to interactions of Ni and Mg; non-immunological roles of these elements are reviewed here. Ni and Mg play roles in some of the same enzyme and endocrine systems, body and cell structures,...
journal_title：Magnesium research
pub_type： 杂志文章,评审
doi：
更新日期：1992-09-01 00:00:00
abstract：:Photosynthetic capacity of chloroplasts is regulated by stromal pH. The pH of the stroma must be maintained higher than external pH during illumination in order to optimize photosynthetic carbon reduction cycle activity. Stromal pH is affected by K+/H+ counterexchange across the chloroplast envelope. Magnesium ion ext...
journal_title：Magnesium research
pub_type： 杂志文章,评审
doi：
更新日期：1993-09-01 00:00:00
abstract：:There is an important functional link between magnesium and calciotropic hormones. PTH stimulates magnesium reabsorption in the renal tubule, absorption in the gut and release of the ion from bone. Magnesium on the other hand is essential for the normal function of the parathyroid glands, metabolism of vitamin D and a...
journal_title：Magnesium research
pub_type： 杂志文章,评审
doi：
更新日期：1995-03-01 00:00:00
abstract：:More and more studies are accumulating about COVID-19. Some aspects of the pathogenesis of the disease recall events occurring in Mg deficiency, such as a drop of T cells, increased plasma concentration of inflammatory cytokines, and endothelial dysfunction. We hypothesize that a low Mg status, which is rather common,...
journal_title：Magnesium research
pub_type： 杂志文章
doi：10.1684/mrh.2020.0465
更新日期：2020-05-01 00:00:00
abstract：:Hypomagnesaemia has been reported among patients undergoing hemodialysis (HD). Recently, a possible correlation between serum magnesium (Mg) and C-reactive protein (CRP) has been stressed. This correlation has been attributed to cytokine production and oxidative stress processes. In this study we aimed to determine th...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2008-09-01 00:00:00
abstract：:Lipid and protein peroxidations were investigated in female patients with magnesium deficit (MD), fibromyalgia (FM) and age matched controls: malondialdehyde and protein carbonyls (PC), as well as serum, leucocyte and erythrocyte magnesium (EMg) were assessed in 20 controls, 25 FM and 16 MD patients. MDA are unchanged...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：1996-12-01 00:00:00
abstract：:Lactating rats fed a 0.055% Mg diet transferred 5.5 +/- SEM 0.3 mg per day of Mg into milk but remained in a slightly positive Mg balance by increasing both food consumption and fractional intestinal Mg absorption. Urinary Mg excretion increased continually during the course of lactation to values double those of non-...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：1989-12-01 00:00:00
abstract：:In therapy it is known that the combination of vitamin B6 and magnesium is beneficial in the treatment of several forms of primary magnesium deficiency. The purpose of the present study was to investigate the effect of complex magnesium supplementation containing mineral bishofit solution (MgCl2 x 6H2O) and pyridoxine...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2002-12-01 00:00:00
abstract：:Traumatic brain injury (TBI) confers a major burden to Western society and effective treatments are urgently required to improve the long-term deficits that inflict TBI survivors. Depletion of intracellular Mg(2+) is a well-known phenomenon occurring after TBI and is associated with poor neurological outcome. However,...
journal_title：Magnesium research
pub_type： 杂志文章,评审
doi：10.1684/mrh.2009.0189
更新日期：2009-12-01 00:00:00
abstract：:We studied the voltage dependence of the inhibitory effects of the Ca2+ antagonist Mg2+, compared to nifedipine, on the transsarcolemmal Ca2+ uptake into primary monolayers of smooth muscle cells obtained from pig coronary arteries. The cellular Ca incorporation was analyzed by liquid scintillation. Depolarization was...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：1997-06-01 00:00:00
abstract：INTRODUCTION:The present study investigated associations between environmental exposure to magnesium (Mg) and the levels of oxidative stress parameters and selected cytokines, and the antioxidant defense system in the seminal plasma of fertile males. MATERIALS AND METHODS:The study population consisted of 57 healthy, ...
journal_title：Magnesium research
pub_type： 杂志文章
doi：10.1684/mrh.2015.0377
更新日期：2015-01-01 00:00:00
abstract：UNLABELLED:Comprehensive analytical review of 44 human studies in 43 publications of oral Magnesium (Mg) therapy for hypertension (HT) shows Mg supplements may enhance the blood-pressure (BP) lowering effect of anti-hypertensive medications (medications) in Stage 1 HT subjects. 9 studies conducted on subjects treated w...
journal_title：Magnesium research
pub_type： 杂志文章
doi：10.1684/mrh.2010.0198
更新日期：2010-03-01 00:00:00
abstract：:Competitive divalent (magnesium and calcium) or monovalent (potassium, lithium and sodium) ion exchange and its influence on a membrane potential formation was studied at biological ligands (BL) such as adenosine triphosphate (ATP), asparagine (Asn) and glutamine (Gln) sites. The sites are dispersed electrochemically ...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2009-03-01 00:00:00
abstract：:Audiogenic seizures triggered by an acoustic stimulus of determined frequency and amplitude have been described in many laboratory animals in many circumstances including magnesium deficiency. This model, recently validated, was used, in DBA/2 mice, to study the preventive neuroprotective effect of 6 wavelengths of th...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2003-03-01 00:00:00
abstract：:Electrolyte abnormalities are a frequent and potentially hazardous complication in the treatment of patients with congestive heart failure. Medical treatment with diuretics and/or digitalis, as well as neurohumoral activation most likely initiated by the compromised cardiac function, contributes to this alteration. Th...
journal_title：Magnesium research
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1992-03-01 00:00:00
abstract：:Ageing is associated with a general decline in physiological functions. Amongst the different aspects of body deterioration, cognitive impairments, and particularly defects in learning and memory, represent one of the most frequent features in the elderly. However, a great variability exists among aged subjects. Clini...
journal_title：Magnesium research
pub_type： 杂志文章,评审
doi：
更新日期：2006-09-01 00:00:00
